• Title/Summary/Keyword: Safety Performance

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Evaluation of Image for Phantom according to Normalization, Well Counter Correction in PET-CT (PET-CT Normalization, Well Counter Correction에 따른 팬텀을 이용한 영상 평가)

  • Choong-Woon Lee;Yeon-Wook You;Jong-Woon Mun;Yun-Cheol Kim
    • The Korean Journal of Nuclear Medicine Technology
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    • v.27 no.1
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    • pp.47-54
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    • 2023
  • Purpose PET-CT imaging require an appropriate quality assurance system to achieve high efficiency and reliability. Quality control is essential for improving the quality of care and patient safety. Currently, there are performance evaluation methods of UN2-1994 and UN2-2001 proposed by NEMA and IEC for PET-CT image evaluation. In this study, we compare phantom images with the same experiments before and after PET-CT 3D normalization and well counter correction and evaluate the usefulness of quality control. Materials and methods Discovery 690 (General Electric Healthcare, USA) PET-CT equiptment was used to perform 3D normalization and well counter correction as recommended by GE Healthcare. Based on the recovery coefficients for the six spheres of the NEMA IEC Body Phantom recommended by the EARL. 20kBq/㎖ of 18F was injected into the sphere of the phantom and 2kBq/㎖ of 18F was injected into the body of phantom. PET-CT scan was performed with a radioacitivity ratio of 10:1. Images were reconstructed by appliying TOF+PSF+TOF, OSEM+PSF, OSEM and Gaussian filter 4.0, 4.5, 5.0, 5.5, 6.0, 6,5 mm with matrix size 128×128, slice thickness 3.75 mm, iteration 2, subset 16 conditions. The PET image was attenuation corrected using the CT images and analyzed using software program AW 4.7 (General Electric Healthcare, USA). The ROI was set to fit 6 spheres in the CT image, RC (Recovery Coefficient) was measured after fusion of PET and CT. Statistical analysis was performed wilcoxon signed rank test using R. Results Overall, after the quality control items were performed, the recovery coefficient of the phantom image increased and measured. Recovery coefficient according to the image reconstruction increased in the order TOF+PSF, TOF, OSEM+PSF, before and after quality control, RCmax increased by OSEM 0.13, OSEM+PSF 0.16, TOF 0.16, TOF+PSF 0.15 and RCmean increased by OSEM 0.09, OSEM+PSF 0.09, TOF 0.106, TOF+PSF 0.10. Both groups showed a statistically significant difference in Wilcoxon signed rank test results (P value<0.001). Conclusion PET-CT system require quality assurance to achieve high efficiency and reliability. Standardized intervals and procedures should be followed for quality control. We hope that this study will be a good opportunity to think about the importance of quality control in PET-CT

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Numerical study on conjugate heat transfer in a liquid-metal-cooled pipe based on a four-equation turbulent heat transfer model

  • Xian-Wen Li;Xing-Kang Su;Long Gu;Xiang-Yang Wang;Da-Jun Fan
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1802-1813
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    • 2023
  • Conjugate heat transfer between liquid metal and solid is a common phenomenon in a liquid-metal-cooled fast reactor's fuel assembly and heat exchanger, dramatically affecting the reactor's safety and economy. Therefore, comprehensively studying the sophisticated conjugate heat transfer in a liquid-metal-cooled fast reactor is profound. However, it has been evidenced that the traditional Simple Gradient Diffusion Hypothesis (SGDH), assuming a constant turbulent Prandtl number (Prt,, usually 0.85 - 1.0), is inappropriate in the Computational Fluid Dynamics (CFD) simulations of liquid metal. In recent decades, numerous studies have been performed on the four-equation model, which is expected to improve the precision of liquid metal's CFD simulations but has not been introduced into the conjugate heat transfer calculation between liquid metal and solid. Consequently, a four-equation model, consisting of the Abe k - ε turbulence model and the Manservisi k𝜃 - ε𝜃 heat transfer model, is applied to study the conjugate heat transfer concerning liquid metal in the present work. To verify the numerical validity of the four-equation model used in the conjugate heat transfer simulations, we reproduce Johnson's experiments of the liquid lead-bismuth-cooled turbulent pipe flow using the four-equation model and the traditional SGDH model. The simulation results obtained with different models are compared with the available experimental data, revealing that the relative errors of the local Nusselt number and mean heat transfer coefficient obtained with the four-equation model are considerably reduced compared with the SGDH model. Then, the thermal-hydraulic characteristics of liquid metal turbulent pipe flow obtained with the four-equation model are analyzed. Moreover, the impact of the turbulence model used in the four-equation model on overall simulation performance is investigated. At last, the effectiveness of the four-equation model in the CFD simulations of liquid sodium conjugate heat transfer is assessed. This paper mainly proves that it is feasible to use the four-equation model in the study of liquid metal conjugate heat transfer and provides a reference for the research of conjugate heat transfer in a liquid-metal-cooled fast reactor.

Oxaliplatin and Leucovorin Plus Fluorouracil Combination Chemotherapy as a First-line versus Salvage Treatment in HER2-negative Advanced Gastric Cancer Patients

  • Hee Seok Moon;Jae Ho Park;Ju Seok Kim;Sun Hyung Kang;Jae Kyu Seong;Hyun Yong Jeong
    • Journal of Digestive Cancer Research
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    • v.6 no.1
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    • pp.25-31
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    • 2018
  • Background: In Korea, stomach cancer is the second most common malignancy and the third leading cause of cancer-related deaths. the time of diagnosis is very important for treatment so early detection and surgery are currently considered the mainstay of treatment, when diagnosed advanced with tumor extension through the gastric wall and direct extension into other organs, with metastatic involvement. Recently, new drugs, drug combinations, and multimodal approaches have been used to treat this disease and In cancers over expressing or amplifying HER2, the combination of cisplatin-fluoropyrimidine-trastuzumab is considered to be the treatment of reference. but At present, the choice of treatment schedule for HER2-negative tumors is based on the medical institution's preferences and adverse effects profile. The aim of this study was to evaluate the effectiveness and safety of using FOLFOX regimen as a first-line therapy or a salvage therapy in the patients with HER2-negative advanced or metastatic gastric cancer. Methods: We retrospective reviewed the patient medical record from March 2012 to July 2017. This study evaluated 113 patients. Sixty-eight patients were treated with the FOLFOX regimen for the first time (first-line group) and 45 patients were treated with the FOLFOX regimen as a second (35 patients) or third (10 patients) chemotherapy (salvage group). Results: In the first-line group, the response rate was 54.9%. In the salvage therapy group, the response rate was 24.4% and The difference was statistically significant (p=0.205). The median TTP of the first-line group was 10.7 months (95% confidence interval [95% CI], 7.8-13.7 months) and that of salvage line group was 6.1 months (95% CI, 3.8-8.4 months). The median OS of the first-line group was 15.8 months (95% CI, 12.7-18.9 months) and that of the salvage therapy group was 10.2 months (95% CI, 8.2-11.9 months). drug toxicity was similar andtolerable between two groups. Conclusion: In patients with unresctable metastatic gastric cancer, after failing to respond to first-line therapy, most patients have no alternative other than second-line therapy because the disease is highly progressive. if the performance status of the patient is good enough to be eligible to treatments beyond best supportive care. FOLFOX regimen can be a considerable therapeutic option for salvage treatment.

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Kidney Tumor Segmentation through Semi-supervised Learning Based on Mean Teacher Using Kidney Local Guided Map in Abdominal CT Images (복부 CT 영상에서 신장 로컬 가이드 맵을 활용한 평균-교사 모델 기반의 준지도학습을 통한 신장 종양 분할)

  • Heeyoung Jeong;Hyeonjin Kim;Helen Hong
    • Journal of the Korea Computer Graphics Society
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    • v.29 no.5
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    • pp.21-30
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    • 2023
  • Accurate segmentation of the kidney tumor is necessary to identify shape, location and safety margin of tumor in abdominal CT images for surgical planning before renal partial nephrectomy. However, kidney tumor segmentation is challenging task due to the various sizes and locations of the tumor for each patient and signal intensity similarity to surrounding organs such as intestine and spleen. In this paper, we propose a semi-supervised learning-based mean teacher network that utilizes both labeled and unlabeled data using a kidney local guided map including kidney local information to segment small-sized kidney tumors occurring at various locations in the kidney, and analyze the performance according to the kidney tumor size. As a result of the study, the proposed method showed an F1-score of 75.24% by considering local information of the kidney using a kidney local guide map to locate the tumor existing around the kidney. In particular, under-segmentation of small-sized tumors which are difficult to segment was improved, and showed a 13.9%p higher F1-score even though it used a smaller amount of labeled data than nnU-Net.

Investigation of Microstructure and Ionic Conductivity of Li1.5Al0.5Ti1.5(PO4)3 Ceramic Solid Electrolytes by B2O3 Incorporation (Li1.5Al0.5Ti1.5(PO4)3 세라믹 고체전해질의 B2O3 첨가에 따른 미세구조 및 이온전도도에 대한 연구)

  • Min-Jae Kwon;Hyeon Il Han;Seulgi Shin;Sang-Mo Koo;Weon Ho Shin
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.36 no.6
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    • pp.627-632
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    • 2023
  • Lithium-ion batteries are widely used in various applications, including electric vehicles and portable electronics, due to their high energy density and long cycle life. The performance of lithium-ion batteries can be improved by using solid electrolytes, in terms of higher safety, stability, and energy density. Li1.5Al0.5Ti1.5(PO4)3 (LATP) is a promising solid electrolyte for all-solid-state lithium batteries due to its high ionic conductivity and excellent stability. However, the ionic conductivity of LATP needs to be improved for commercializing all-solid-state lithium battery systems. In this study, we investigate the microstructures and ionic conductivities of LATP by incorporating B2O3 glass ceramics. The smaller grain size and narrow size distribution were obtained after the introduction of B2O3 in LATP, which is attributed to the B2O3 glass on grain boundaries of LATP. Moreover, higher ionic conductivity can be obtained after B2O3 incorporation, where the optimal composition is 0.1 wt% B2O3 incorporated LATP and the ionic conductivity reaches 8.8×10-5 S/cm, more than 3 times higher value than pristine LATP. More research could be followed for having higher ionic conductivity and density by optimizing the processing conditions. This facile approach for establishing higher ionic conductivity in LATP solid electrolytes could accelerate the commercialization of all-solid-state lithium batteries.

A Study on the Performance of Ni Catalysts in Biogas Steam Reforming: Impact of Supports and Precipitation Agent Injection Rates (바이오가스 수증기 개질 반응용 Ni 촉매 성능 연구: 지지체 및 침전제 주입 속도에 따른 영향)

  • Ji-Hyeon Gong;Min-Ju Kim;Kyung-Won Jeon;Won-Jun Jang
    • Clean Technology
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    • v.29 no.4
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    • pp.327-332
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    • 2023
  • This study investigated synthesis gas production via steam reforming of biogas. Ni-Al2O3 and Ni-CeO2 catalysts were synthesized using the co-precipitation method, with controlled precipitation agent injection rates. Catalytic performances were tested at various temperatures, with a gas composition ratio of CH4:CO2:H2O = 1:0.67:3 and a gas hourly space velocity (GHSV) of 647,000 mL h-1 gcat-1. The rate of precipitation agent injection influenced the characteristics of the catalysts depending on the type of support used. As the temperature increased, both the CO2 reforming of methane and the reverse water gas shift reactions occurred. The Ni-Al2O3 catalyst, synthesized with a single injection of the precipitation agent, exhibited the best catalytic activity under conditions with sufficient steam supply among the prepared catalysts, due to its high Ni dispersion.

Exploratory Study on Enhancing Cyber Security for Busan Port Container Terminals (부산항 컨테이너 터미널 사이버 보안 강화를 위한 탐색적 연구)

  • Do-Yeon Ha;Yul-Seong Kim
    • Journal of Navigation and Port Research
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    • v.47 no.6
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    • pp.437-447
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    • 2023
  • By actively adopting technologies from the Fourth Industrial Revolution, the port industry is trending toward new types of ports, such as automated and smart ports. However, behind the development of these ports, there is an increasing risk of cyber security incidents and threats within ports and container terminals, including information leakage through cargo handling equipment and ransomware attacks leading to disruptions in terminal operations. Despite the necessity of research to enhance cyber security within ports, there is a lack of such studies in the domestic context. This study focuses on Busan Port, a representative port in South Korea that actively incorporates technology from the Fourth Industrial Revolution, in order to discover variables for improving cyber security in container terminals. The research results categorized factors for enhancing cyber security in Busan Port's container terminals into network construction and policy support, standardization of education and personnel training, and legal and regulatory factors. Subsequently, multiple regression analysis was conducted based on these factors, leading to the identification of detailed factors for securing and enhancing safety, reliability, performance, and satisfaction in Busan Port's container terminals. The significance of this study lies in providing direction for enhancing cyber security in Busan Port's container terminals and addressing the increasing incidents of cyber security attacks within ports and container terminals.

Text Mining-Based Analysis of Hyundai Automobile Consumer Satisfaction and Dissatisfaction Factors in the Chinese Market: A Comparison with Other Brands (텍스트 마이닝을 이용한 현대 자동차 중국시장 소비자의 만족 및 불만족 요인 분석 연구: 다른 브랜드와의 비교)

  • Cui Ran;Inyong Nam
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.1
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    • pp.539-549
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    • 2024
  • This study employed text mining techniques like frequency analysis, word clouds, and LDA topic modeling to assess consumer satisfaction and dissatisfaction with Hyundai Motor Company in the Chinese market, compared to brands such as Toyota, Volkswagen, Buick, and Geely. Focusing on compact vehicles from these brands between 2021 and 2023, this study analyzed customer reviews. The results indicated Hyundai Avante's positive factors, including a long wheelbase. However, it also highlighted dissatisfaction aspects like Manipulate, engine performance, trunk space, chassis and suspension, safety features, quantity and brand of audio speakers, music membership service, separation band, screen reflection, CarLife, and map services. Addressing these issues could significantly enhance Hyundai's competitiveness in the Chinese market. Previous studies mainly focused on literature research and surveys, which only revealed consumer perceptions limited to the variables set by the researchers. This study, through text mining and comparing various car brands, aims to gain a deeper understanding of market trends and consumer preferences, providing useful information for marketing strategies of Hyundai and other brands in the Chinese market.

Impact of an Instrumental Daily Living Activities Occupational Therapy Program for Adults With Developmental Disabilities on Their Daily Living Activities and Quality of Life (성인 발달장애인 대상 수단적 일상생활활동 작업치료 프로그램이 일상생활활동 및 삶의 질에 미치는 영향)

  • Jeong, Eun-Hwa
    • Therapeutic Science for Rehabilitation
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    • v.13 no.2
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    • pp.85-94
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    • 2024
  • Objective : This study aimed to determine the impact of an instrumental daily living activity program for adults with developmental disabilities on their daily living activities and quality of life (QOL). Methods : This study used a single-group pre-test-post-test experimental design. Participants comprised 17 adults with developmental disabilities from the Welfare Center for the Disabled. This program consisted of 10 sessions, including pre- and post-assessments, pertaining to training and education on grocery shopping, meal preparation and cleaning, home management, safety, and emergency management. The evaluation tools used in this study were the Quality of Life Questionnaire, Korean version of the Life Space Assessment (K-LSA), and Korean version of the Instrumental Activities of Daily Living (K-IADL). Results : There was a statistically significant difference in the QOL and K-IADL scores before and after the instrumental activities of daily living occupational therapy program, and there was no statistically significant difference in the K-LSA scores. Conclusion : This study confirmed that implementing an IADL program for adults with developmental disabilities had a positive impact on performance and QOL. For adults with developmental disabilities to participate in daily life and society, interventions for work participation, including training in activities of daily living, must be expanded.

Field Applicability Evaluation Experiment for Ultra-high Strength (130MPa) Concrete (초고강도(130MPa) 콘크리트의 현장적용성 평가에 관한 실험)

  • Choonhwan Cho
    • Journal of the Society of Disaster Information
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    • v.20 no.1
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    • pp.20-31
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    • 2024
  • Purpose: Research and development of high-strength concrete enables high-rise buildings and reduces the self-weight of the structure by reducing the cross-section, thereby reducing the thickness of beams and slabs to build more floors. A large effective space can be secured and the amount of reinforcement and concrete used to designate the base surface can be reduced. Method: In terms of field construction and quality, the effect of reducing the occurrence of drying shrinkage can be confirmed by studying the combination of low water bonding ratio and minimizing bleeding on the concrete surface. Result: The ease of site construction was confirmed due to the high self-charging property due to the increased fluidity by using high-performance water reducing agents, and the advantage of shortening the time to remove the formwork by expressing the early strength of concrete was confirmed. These experimental results show that the field application of ultra-high-strength concrete with a design standard strength of 100 MPa or higher can be expanded in high-rise buildings. Through this study, we experimented and evaluated whether ultra-high-strength concrete with a strength of 130 MPa or higher, considering the applicability of high-rise buildings with more than 120 floors in Korea, could be applied in the field. Conclusion: This study found the optimal mixing ratio studied by various methods of indoor basic experiments to confirm the applicability of ultra-high strength, produced 130MPa ultra-high strength concrete at a ready-mixed concrete factory similar to the real size, and tested the applicability of concrete to the fluidity and strength expression and hydration heat.