• Title/Summary/Keyword: Safe-site

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Sutureless Gastroduodenostomy (무봉합 위십이지장 문합술)

  • Lee, Jong-In;Kim, Jin-Young;Jeong, Jin-Ho
    • Journal of Gastric Cancer
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    • v.2 no.1
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    • pp.29-32
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    • 2002
  • A gastroduodenostomy is the most physiological reconstruction after a distal gastrectomy. However, a gastroduodenostomy with either sutures or staples has many complications. These include bleeding, leakage and stenosis. A sutureless gastroduodenostomy with a biofragmentable anastomosis ring (BAR) in was used adenocarcinoma patients to prevent these complications from 1999. A BAR is composed of polyglycolic acid and Barium sulfate to allow for X-ray visualization. Hardy in first introduced the BAR in 1985. Since then, it has been used in an anastomosis of the colon or small bowel surgery but its use in a gastroduodenostomy is the first trial in the world. A 70 year male patient, old who received a subtotal gastrectomy (Billroth I), underwent a A sutureless gastroduodenostomy with a BAR. The gastroduodenostomy with the BAR was watertight and maintained the initial burst strength in the gastrografin X-ray study performed at the postoperative 1 week. The BAR began to fragment 3 weeks after the operation and disappeared from the digestive tract completely. The diameter of the anastomosis site was sufficient for passed foods. No other secondary changes from remained foreign bodies were found in the endoscopic examination. In a second operation to treat a primary hepatoma, there was no adhesive changes around the gastroduodenostomy site. In conclusion, a sutureless gastroduodenostomy with BAR is a safe, easy and efficient reconstructive method after a distal gastrectomy.

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Feasibility of Management Plan in Electric Power Structure using Close-Range Photogrammetry (근거리사진측량방법을 이용한 전력구조물의 유지관리방안)

  • 김감래;김명배
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.13 no.2
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    • pp.219-228
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    • 1995
  • The facilities of electric power plant which were constructed in and after the 1960's are superannuated in these days. We are expanding them applying an incressary to secure a safe plan for them. In this study, for a feasibility of management plan in electric power structure, a RC test prame was manufactured for monitoring and calculation of variation using close range photogrammetry. On the basis of this data, monitoring and calculating of variation in soil wall building site were carried out. Also a survey and analysis of a influence which occured to a structure near by exactitude site. All of these afford data for a management plan in electric power structure.

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Design and Implementation of LPF to reduce EMI from 2.5Gbps SDH system (2.5Gbps SDH 시스템 전자파 감소용 저역통과필터 설계 및 제작)

  • 이성원;김영범
    • Journal of the Institute of Convergence Signal Processing
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    • v.3 no.2
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    • pp.45-52
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    • 2002
  • EMI(Electromagnetic Interface) is a measure of electomagnetic radiation from equipment in the range of 10KHz to 3GHz, and can cause unexpected reactions of electronics/electrical equipment. In this study, for safe and stable communication operation, a STGU(System Timing Genetation Unit), which is a 2.5Gbps SDH System and a major EMI source, was employed to simulate electromagnetic interface. In On-Site test, the power of fundamental frequency of EMI of interest and its harmonics were measured. Also, a low pass filter at cut-off frequency of 2GHz was specifically designed to minimize the effect of EMI between electronic components. When the low pass filter was implemented within the STGU, the power of EMI decreased more than 20dBm. Finally, when TIE and MTIE, two important quality measure in synchronous reference clcok, was assessed, ITU-T G8l3 requirements are satisfied.

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Feasibility Study of the Combustible Gab Control System Following a LOCA (냉각재 상실사고시 가연성 가스제거 계통의 타당성 조사)

  • Hyung Won Lee;Chang Sun Kang
    • Nuclear Engineering and Technology
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    • v.16 no.4
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    • pp.217-223
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    • 1984
  • The feasibility of not employing recombiners rather using the postaccident Purge system alone to control hydrogen concentration in the containment following a LOCA, is analyzed in this paper. For this study, the hydrogen concentration in the containment, hydrogen removal through the purge system, and additional off-site dose due to hydrogen purge were calculated. The economic justification of a hydrogen recombiner system (2 recombiners) was also investigated by using the cost benefit concept. As a result, the purge system is sufficient to maintain the hydrogen concentration at a safe level without hydrogen recombiners, and it meets the dose limit requirements set forth in 10 CFR part 100. A hydrogen recombiner system would be justified based on cost-benefit concept for common use in a site with 4 units or more.

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Study on the Mechanism of P-glycoprotein Inhibitory Activity of Silymarin in Human Breast Cancer Cell

  • Kwon, Young-Joo;Jung, Ho-Jin;Lee, Hwa-Jeong
    • Journal of Pharmaceutical Investigation
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    • v.36 no.5
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    • pp.315-320
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    • 2006
  • Silymarin showed P-glycoprptein(P-gp) inhibitory activity as much as verapamil, a well-known P-gp inhibitor, by decreasing $IC_{50}$ value of daunomycin(DNM)($16.0{\pm}0.7{\mu}M$), increasing the DNM accumulation($224.9{\pm}3.2%$), and decreasing DNM efflux($58.5{\pm}6.7%$), concurrently. In this study, we clarified the mechanism of action of silymarin for P-gp inhibitory function. First, silymarin may bind to the ATP-binding site and thus, prevent ATP hydrolysis. Second, the P-gp inhibitory activity of silymarin is not related to changing the cellular P-gp level. Third, the cytotoxicity of silymarin was increased in the presence of verapamil, reflecting that silymarin is a competent P-gp substrate against verapamil in the P-gp-overexpressed adriamycin-resistant MCF-7 breast cancer(MCF-7/ADR) cells. Conclusively, silymarin had the P-gp inhibitory activity through the action of competent binding to the P-gp substrate-binding site. Therefore, silymarin can be a good candidate for safe and effective MDR reversing agent in clinical chemotherapy by administering concomitantly with anticancer drugs.

A case histories on the detection of weak zone using electrical resistivity and EM surveys in planned tunnel construction site (터널 건설 예정지구에서의 전기비저항 탐사와 전자탐사의 적용을 통한 연약대 탐지에 대한 사례 연구)

  • 권형석;송윤호;이명종;정호준;오세영;김기석
    • Proceedings of the Korean Geotechical Society Conference
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    • 2002.03a
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    • pp.63-70
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    • 2002
  • In tunnel construction, the information on the rock quality and the location of fault or fracture are crucial for economical design of support pattern and for safe construction of the tunnel. The grade of rock is commonly estimated through the observation with the naked eye of recovered cores in drilling or from physical parameters obtained by their laboratory test. Since drilling cost is quite expensive and terrains of planned sites for tunnel construction are rough in many cases, however, only limited information could be provided by core drilling Electrical resistivity and EM surveys may be a clue to get over this difficulty. Thus we have investigated electrical resistivity and EM field data providing regional Information of the rock Quality and delineating fault and fracture over a rough terrain. In this paper, we present some case histories using electrical resistivity and EM survey for the site investigation of tunnel construction. Through electrical resistivity and EM survey, the range and depth of coal seam was clearly estimated, cavities were detected in limestone area, and weak zones such as joint, fault and fracture have been delineated.

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Cre-Lox: A Tool for Removal of Marker Genes to Make GM Foods Safe

  • Zargar, Sajad M.;Mushtaq, Roohi;Joshi, Manisha;Prasad, D. Theertha;Bhat, Nazir Ahmad;Agrawal, Ganesh Kumar;Rakwal, Randeep
    • Journal of Crop Science and Biotechnology
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    • v.10 no.2
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    • pp.73-78
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    • 2007
  • The green revolution has significantly helped in increasing the food production. So far, various breeding methods have been exploited, besides them recombination DNA technology provides another approach for increasing the food production. By means of this technology the losses in food production incurred by various biotic and abiotic stresses can be effectively controlled. In most of the transgenic studies scientists have used antibiotic resistant genes as markers for easy selection of transformants but there are risks involved in use of GM foods. To make such foods safer and environment friendly we have discussed a novel strategy i.e. Cre-lox which involves site specific recombination. By means of Cre-lox the marker genes can be specifically removed once the selection of transformants is over. In addition, this strategy can be used to module the hybrid chromosomes, avoid gene silencing and incorporate single copy of a transgene for its higher expression.

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Current treatment and disposal practices for medical wastes in Bujumbura, Burundi

  • Niyongabo, Edouard;Jang, Yong-Chul;Kang, Daeseok;Sung, Kijune
    • Environmental Engineering Research
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    • v.24 no.2
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    • pp.211-219
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    • 2019
  • Since improper management practices of solid medical waste (SMW) could potentially result in serious health risks and environmental problems, it is very important to properly treat and dispose of the medical wastes. In this study, current practices of SMW management from storage to final disposal stage in 12 health care facilities (HCFs) of Burundi were investigated using the official government reports. The results showed that 75% and 92% of HCFs used uncovered wheelbarrows and trucks for on-site or off-site SMW transportation, respectively, indicating that most transportation equipment and waste workers are not safely protected. The results also showed that 92.8% of SMW (15,736.4 ton) from all 12 HCFs were inappropriately disposed of through uncontrolled land disposal and incineration. If pharmaceutical wastes and discarded medical plastics (29.5% of SMW) can be separated and treated properly, the treatment costs can be reduced and resource savings can be achieved. Raising awareness of healthcare workers and general public about potential health effects arising from improper SMW management, sufficient financial and human resources for the treatment facilities (especially incinerators), and effective regulations and guidelines for transportation and treatment of SWM are some of the major tasks for safe and sustainable medical waste management in Burundi.

A Comparative Study on the Deployment Characteristics of Korean and Foreign Mobile Hospitals Responding to Disasters (국내외 재난대응 이동형 병원의 배치특성 비교분석 연구)

  • Yang, Minkyu;Suh, Sangwook;Lee, Young
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.25 no.1
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    • pp.29-40
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    • 2019
  • Purpose: The purpose of this study is to analyze the deployment characteristics of korean and foreign mobile hospitals and to draw out the advantages and disadvantages based on the movement of patients. Methods: The arrangement and user movement lines of foreign mobile hospitals which were actually utilized, and the arrangements and user movement lines of korean mobile hospitals are compared and analyzed. Based on the results of the comparative analysis, we suggest the optimal placement of mobile hospital in Korea. Results: The recently developed Korean mobile hospitals have made many improvements. However, there is no practical use case for the mobile hospital in Korea, so it is necessary to establish the basis for the mobile hospital development site and the site access considerations. In addition, there is no detailed analysis of the movement of the administrators other than the medical staff, and it is considered that research on safe waste disposal is further needed. Implications: It is highly likely to be used as a basic data to find out the combination method of mobile hospitals that can efficiently deal with disasters through the arrangement and movement analysis of mobile hospitals in Korea and abroad.

Evaluation of Present Status from Health Technology Assessment(HTA) through case analysis in dentistry (치의학분야 사례분석을 통한 신의료기술평가 현황 평가)

  • Son, Gi Tae;Yang, Seung-Min
    • The Journal of the Korean dental association
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    • v.57 no.6
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    • pp.316-324
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    • 2019
  • The new medical technology assessment system has a basic goal of protecting the public's health rights and promoting the development of the new medical technology with safe and effective medical technology that has been scientifically proven. The purpose of this study is to contribute to the activation of the new medical technology evaluation system by analyzing the application cases of the dental field after the implementation of the new medical technology evaluation system and proposing an efficient approach to approach the new medical technology evaluation system. The number of related literature and medical technology evaluation results are not significant in dental applications, the number of cases and the length of follow-up period of the relevant medical technology adopted as the new medical technology was far higher. As the speed of medical technology development increases, medical technology is expected to develop in the dental field as well. To introduce the medical technology to the clinical site, access to the correct direction of evidence is required to collect and objectify data at the medical site in order to prepare a literary basis for the medical technology.

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