• 제목/요약/키워드: Safe and health

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Endocrine Disruption Potentials of Bisphenol A Alternatives - Are Bisphenol A Alternatives Safe from Endocrine Disruption?

  • Ji, Kyunghee;Choi, Kyungho
    • 한국환경보건학회지
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    • 제39권1호
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    • pp.1-18
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    • 2013
  • Objectives: Although a great body of knowledge is available on the toxicity of bisphenol A (BPA), little is known about that of BPA alternatives, such as bisphenol analogues (BPs) or $Tritan^{TM}$ copolyesters. This review provides a summary of the available information on the toxicity of BPs and three components of $Tritan^{TM}$, with a special focus on endocrine disruption. Methods: We collected from the literature a battery of in vitro and in vivo assay data developed to assess endocrine disruption of four BPs (bisphenol AF, B, F, and S) and three major components of $Tritan^{TM}$ ((di-methylterephthalate (DMT), 1,4-cyclohexanedimethanol (CHDM), and 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD)). Results: Several alternative compounds were identified as possessing comparable or even greater endocrinedisrupting effects than BPA in in vitro and in vivo studies. Conclusions: Potential endocrine disruption of BPA alternatives requires further studies on health consequences in experimental animals and in humans following longer term exposure.

산업안전보건관리비 계상기준 개선방안 연구 (A Study on Improving the Occupational Safety and Health Management Cost Calculation Standards)

  • 안방율;송태석
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2020년도 봄 학술논문 발표대회
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    • pp.169-170
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    • 2020
  • Occupational Safety and Health Management Cost, used to protect workers in Korean construction worksites and to create safe working environments, is a legally managed expense item. As this cost item is grounded on the Occupational Safety and Health Act, it is always implemented. However, because there is a ceiling on its rates, insufficient amounts of Safety Management Costs are often allocated to worksites, with the money not being used to areas essential to worker safety. As such, the current study raises the need to develop a set of standards to enable some items under the Occupational Safety and Health Management Costs-appropriated under the rate of indirect costs-to be appropriated as direct construction costs. As a preliminary step in this effort, the current study will provide basic data that can be used to create construction cost calculation standards for items that can be calculated as direct construction costs.

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A call for action from workers, local residents, and consumers: a safe society from toxic chemicals

  • Kim, Shinbum;Im, Sanghyuk;Choi, Youngeun;Park, Soomi;Hyun, Jaesoon;Lee, Kyung Seok;Lee, Sunimm;Lee, Sung-nan;Seo, Jeongri;Kim, Ju Hee;Na, Hyunsun;Kim, Minsun;Korean Society for Environmental Health and Toxicology;Korean Society for Occupational and Environmental Medicine;Korean Industrial Hygiene Association;Korean Academic Society of Occupational Health Nursing;Association of Physicians for Humanism;Korean Pharmacists for Democratic Society;Korean Dentists for Democratic Society and the Association of Korea Doctors for Health Rights
    • Environmental Analysis Health and Toxicology
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    • 제31권
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    • pp.20.1-20.7
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    • 2016

Phytochemicals That Act on Synaptic Plasticity as Potential Prophylaxis against Stress-Induced Depressive Disorder

  • Soojung, Yoon;Hamid, Iqbal;Sun Mi, Kim;Mirim, Jin
    • Biomolecules & Therapeutics
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    • 제31권2호
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    • pp.148-160
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    • 2023
  • Depression is a neuropsychiatric disorder associated with persistent stress and disruption of neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses and reduced size of the hippocampus and prefrontal cortex. These alterations are associated with neural dysfunction, including mood disturbances, cognitive impairment, and behavioral changes. Synaptic plasticity is the fundamental function of neural networks in response to various stimuli and acts by reorganizing neuronal structure, function, and connections from the molecular to the behavioral level. In this review, we describe the alterations in synaptic plasticity as underlying pathological mechanisms for depression in animal models and humans. We further elaborate on the significance of phytochemicals as bioactive agents that can positively modulate stress-induced, aberrant synaptic activity. Bioactive agents, including flavonoids, terpenes, saponins, and lignans, have been reported to upregulate brain-derived neurotrophic factor expression and release, suppress neuronal loss, and activate the relevant signaling pathways, including TrkB, ERK, Akt, and mTOR pathways, resulting in increased spine maturation and synaptic numbers in the neuronal cells and in the brains of stressed animals. In clinical trials, phytochemical usage is regarded as safe and well-tolerated for suppressing stress-related parameters in patients with depression. Thus, intake of phytochemicals with safe and active effects on synaptic plasticity may be a strategy for preventing neuronal damage and alleviating depression in a stressful life.

Production of clothes for beach volleyball players: Safe against ultraviolet radiation damage

  • He Huang
    • Geomechanics and Engineering
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    • 제32권6호
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    • pp.627-637
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    • 2023
  • Volleyball is an international sport with many fans. This sport has made significant progress in schools and clubs. Volleyball is suitable for all age groups and can be used in different environments. It has many social and physical benefits. During the game provides special physical training for the players and is considered one of the most exciting games. Another type of volleyball is beach volleyball, a beach sport and one of the Olympic sports held on the sand with the same rules as volleyball. This sport is usually played in coastal areas, especially with wide sandy beaches. Because this sport is played in open spaces, the players stay in this space for a long time and are exposed to dangerous ultraviolet radiation. It is a wavelength of light in the range of electromagnetic waves with a wavelength between 10 and 400 nm. This wavelength is shorter than visible light and more protracted than X-ray. Ultraviolet (UV) rays are naturally present in sunlight and include about 10% of all waves emitted from the sun's surface. Prolonged exposure to ultraviolet light causes acute and chronic damage to the skin and vision and even destroys the entire immune system. Different covers of the earth's surface reflect different amounts of UV rays. For example, snow cover, sand, and seawater surface reflect this radiation. Therefore, the health of volleyball players is in danger due to this harmful radiation. This work aims to introduce a type of clothing made of nanoparticles that can repel ultraviolet rays and protect beach volleyball players whose health is at risk from this radiation.

Occupational Health and Safety and Organizational Commitment: Evidence from the Ghanaian Mining Industry

  • Amponsah-Tawiah, Kwesi;Mensah, Justice
    • Safety and Health at Work
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    • 제7권3호
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    • pp.225-230
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    • 2016
  • Background: This study seeks to examine the relationship and impact of occupational health and safety on employees' organizational commitment in Ghana's mining industry. The study explores occupational health and safety and the different dimensions of organizational commitment. Methods: A cross-sectional survey design was used for this study. The respondents were selected based on simple random sampling. Out of 400 questionnaires administered, 370 were returned (77.3% male and 22.7% female) and used for the study. Correlation and multiple regression analysis were used to determine the relationship and impact between the variables. Results: The findings of this study revealed positive and significant relationship between occupational health and safety management, and affective, normative, and continuance commitment. Additionally, the results revealed the significant impact of occupational health and safety on affective, normative, and continuance commitment. Conclusion: Management within the mining sector of Ghana must recognize the fact that workers who feel healthy and safe in the performance of their duties, develop emotional attachment and have a sense of obligation to their organization and are most likely committed to the organization. Employees do not just become committed to the organization; rather, they expect management to first think about their health and safety needs by instituting good and sound policy measures. Thus, management should invest in the protection of employees' health and safety in organizations.

임신부에서 약물의 안전사용을 위한 연구의 필요성 (Necessity of Research for Safe Drug use in Pregnant Women)

  • 한정열;조금준;오정미
    • 한국모자보건학회지
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    • 제21권3호
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    • pp.159-165
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    • 2017
  • The thalidomide tragedy in the 1960s has resulted in a perpetuation of a certain perception amongst physicians and pregnant women that the use of medication during pregnancy is a potential teratogen. Consequently, physicians hesitate in prescribing medication to pregnant women. In addition, pregnant women often refuse medication despite therapeutic necessity because of this existing perception. Recently there have been frequent adverse pregnancy outcomes related to the recurrence of chronic diseases, such as hypertension and diabetes, following pregnancy in older women. And there are lots of unnecessary termination of pregnancy due to the of information of medication exposed to medication following over 50% of unintended pregnancy. In light of this, better dissemination of information regarding the safe usage of medication for pregnant women is required. This would not only be cost-effective in terms of medical expenditure, but also prove beneficial for the treatment of diseases. In addition, Korea needs to adapt to the increasing changes of the international information system regarding supporting the safe usage of medication during pregnancy. An example of this is shown by the recent changes to the labeling of medication by the United States Food and Drug Administration. The new labeling includes information on the risk of usage, rather than just an arbitrary alphabetic classification of B, C, D, or X. Furthermore, this information is limited in Korea because of the lack of research, which in turn is due to several limitations on ethics and methodology, as well as present regulations on the research of pregnant women. From this, we can learn that government support is critical for the establishment of research so that we can alter the perception that all medication is harmful to pregnant women.

Knowledge on Sudden Unexplained Infant Death-related Safe Sleep Practices and Infant Cardiopulmonary Resuscitation in Pediatric Nurses

  • Cho, Jung Ae;Sohn, Min;Lee, Sangmi;Ahn, Young Mee
    • Child Health Nursing Research
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    • 제26권4호
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    • pp.454-462
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    • 2020
  • Purpose: Sudden unexplained infant death (SUID) is a major contributor to infant mortality, and pediatric nurses have the responsibility to educate parents on SUID-reducing strategies. This study was conducted to measure pediatric nurses' knowledge of SUID-related safe sleep practices (K-SSSP) and infant cardiopulmonary resuscitation (K-ICPR). Methods: In total, 136 pediatric nurses were administered a survey including K-SSSP (13 items), K-ICPR (5 items), confidence in K-SSSP education (1 item; 5 points), and other factors relating to SUID experiences or education. Results: The correct answer rates of the K-SSSP and K-ICPR were 62.6% and 62.5%, retrospectively. The mean score for confidence in K-SSSP education was 2.6±0.9. Only 18 nurses (13.2%) responded that they educated parents on the content of the K-SSSP, while 76 nurses had received education on SUID. Positive relationships were observed between K-SSSP scores and higher education, between K-ICPR scores and having own child(ren) and clinical experience, and between confidence in K-SSSP education and higher education or having one's own child(ren). Nurses caring for newborns performed more SUID education than nurses working in other units. Conclusion: There is a profound need to implement a systemic educational program on SUID and strategies to reduce SUID for pediatric nurses.

최대실험안전틈새(MESG)와 폭발압력의 상관관계에 대한 연구 (A Study on the Correlation of MESG and Explosion Pressure)

  • 황경용;신운철;이택기
    • 한국가스학회지
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    • 제20권1호
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    • pp.29-39
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    • 2016
  • 폭발성 가스가 존재하는 위험장소에서 사용하는 전기기기는 폭발성 가스의 점화원이 되지 않도록 설계되어야 한다. 내압방폭 구조의 설계는 전기 스파크를 발생시키는 부품을 가진 용기가 내부에서 가스나 증기의 폭발시 최대 압력에 견디고 내부 화염이 외부 가스나 증기 폭발로 전파되지 않도록 설계되어야 한다. 이 논문은 화염 틈새를 통해 외부로 분사되는 연소 생성물의 분사가 외부 가스나 증기를 점화시킬 정도의 온도나 에너지를 가질 수 없도록 하는 MESG(Maximum Experimental Safe Gap)의 중요한 물리적인 메커니즘에 대해 설명하였다. IEC 60079-20-1:2010 기준에 의해 프로판과 아세틸렌의 MESG를 실험하여 MESG 값을 측정하고 가스폭발시의 최대 폭발압력을 측정하였다. 결과로는 최소 MESG가 측정될 때 가스의 농도는 화학당량 농도보다 높고 폭발압력은 최소 MESG에서 가장 높게 나타났다.

지역사회 중·소규모 치과의료기관 인증 평가지표 개발 (Development of Evaluation Indicators for the Accreditation of Small-Sized Dental Hospitals within Local Communities)

  • 권수진;배성권
    • 보건의료산업학회지
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    • 제9권4호
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    • pp.1-12
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    • 2015
  • Objectives : The aim of this research was to develop evaluation indicators that ensure safe services and enhance the quality of small-sized dental hospitals within local communities to prepare for the dental hospital accreditation system. Methods : Materials and data from a total of 460 respondents were analyzed after quality improvement indicators were formed by surveying experts and studying documents in Korea and abroad, and by conducting a survey from August 21, 2013 to September 30, 2013 for validation purposes. Results : Based on the results of factor analysis. all measured items appeared to be statistically significant with a factor loading score of at least 0.5, and the correlation between the factors all appeared to be high as well. The goodness-of-fit for the model also appeared to be within the recommended acceptance level. Thus, the proposed evaluation indicators for dental hospital accreditation developed in this study consisted of a total of seven major category factors and a total of 91 detailed items. Conclusions : Furthermore, the results suggest that the evaluation indicators can be used to improve the quality and to ensure the safe services of dental hospitals in local communities.