• 한국식품저장유통학회지
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• 제31권1호
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• pp.1-14
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• 2024

The utilization of coatings composed of bio-based materials in the processing and preservation of meat presents an environmentally conscious, secure, cost-effective, and superior method for prolonging the storage life of meat while also preserving its nutritional value. In this study, changes in physical, chemical, and microbiological characteristics of freshly cut beef coated with distilled water (control) and keratin-starch composites (K-S) functionalized with 0.0-, 0.2-, 0.6-, and 1.0-mL avocado peel polyphenolic-rich extract (APPPE) kept at 4℃ for 12 days were evaluated periodically at 3-day interval using standard techniques. Keratin was extracted from waste feathers, while starch was obtained from ginger rhizomes. Following a 12-day storage period, beef coated with APPPE-enriched K-S composites exhibited a significant (p<0.05) improvement in shelf life by minimizing deteriorative changes in pH and color (as determined by metmyoglobin level) in addition to inhibiting oxidative changes in lipids (as determined by TBARS level) and proteins (protein carbonyl level) in comparison to control and K-S composite without APPPE. Furthermore, microbial growth was significantly (p<0.05) suppressed in meat coated with K-S composite functionalized with APE at 0.6 and 1.0 mL compared to the control. The study suggested that APPPE-enriched K-S composite could offer an eco-friendly and safe food preservation technique for fresh meat.

• 한국산학기술학회논문지
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• 제18권7호
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• pp.193-199
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• 2017

본 연구의 목적은 노인의 낙상두려움, 일상생활수행능력, 삶의 질 정도를 낙상경험유무, 만성질환유무, 거주지역별로 비교분석하여 결과를 지역노인의 삶의 질을 증진시키기 위한 낙상방지 프로그램의 개발에 기초자료를 제공하고자 함이다. 본 연구는 J시의 시내 경로당 4곳과 농촌지역 주민 센터 4곳에서 지역 노인 185명을 대상으로 2016년 8월 15일부터 2016년 9월 17일까지 시행 되었다. 본 연구의 결과를 보면 낙상경험유무별 낙상두려움, 일상생활수행능력, 삶의 질 비교분석 결과 모든 항목에서 통계적으로 유의한 차이가 없었고, 만성질환유무별 낙상두려움, 일상생활수행능력, 삶의 질 비교에서는 낙상 두려움과 삶의 질에서 통계적으로 유의한 차이를 보였다. 그리고 거주지역별 낙상두려움, 일상생활수행능력, 삶의 질 비교에서는 일상생활수행능력 및 삶의 질에서 통계적으로 유의한 차이를 보였다. 낙상두려움, 일상생활수행능력, 삶의 질 간의 상관관계를 보면 낙상두려움은 일상생활수행능력과 유의하게 음의 상관관계를 보이고 있고(r=-.386, p<.000), 일상생활수행능력과 삶의 질과의 관계는 유의하게 양의 상관관계가 있음을 확인하였다(r=.513, p<.000). 따라서 노인의 낙상두려움을 낮추기 위한 안전한 환경을 마련이 중요함을 인식하여 환경개선교육 프로그램의 개발이 필요하고 노인들의 일상생활에서 낙상관련 필수적인 정보들을 얻을 수 있는 시스템 개발이 되어야하며, 일상생활수행능력을 높일 수 있는 프로그램을 삶의 질이 증진될 수 있음을 알 수 있다.

• 한국임상약학회지
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• 제23권2호
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• pp.123-128
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• 2013

Purpose: The aim of study was to investigate the racial or ethnic differences in FDA-approved medications. Methods: Data on racial-based differences of drugs in PDR (Physician's Desk Reference) were analyzed by searching with keywords, "ETHNIC" and "RACE". Results: There were descriptions related to "ETHNIC" in product directions of 53 cases and "RACE" in 266 cases in 2010 PDR. After excluding 30 cases of duplicates, 289 cases were shown of which 28 cases were verified to demonstrate racial or ethnic differences. Drug category showing the higher racial or ethnic differences was cardiovascular drugs (7), followed by alimentary tract and metabolism drugs (6), nervous system drugs (5), and antineoplastic and immunomodulating agents (3). Pharmacokinetic differences between race and ethnicity were observed most frequently; differences in AUC or Cmax showed in 15 drugs and clearance differences in 7 drugs. Conclusions: This study identified the racial differences in medication usage in PDR. Therefore, the results can contribute to safe use of medication in real clinical settings in regards to the racial or ethnic differences.

• 동아시아식생활학회지
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• 제11권4호
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• pp.268-273
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• 2001

This study was performed to investigate the effects of HBM(Healthy Body Maker) on the weight loss and serum cholesterol level of rats. Twenty male Sprague-Dawley rats weighing 200$\pm$5g were grouped into 2. Rats were raised for 6 weeks with diet containing 0% and 5% of HBM. 1. There were no clinical signs for all the experimental period(6 weeks) in 0% and 5% groups. 2. At 3 and 6 weeks. body weight of 5% HBM group was significantly lower than that of control group. respectively(p<0.05, p<0.01). 3. At 4 weeks. the level of MCHC of 5% HBM group was significantly higher than that of control group(p<0.01) And at 6 weeks the level of RBC and Hct of 5% HBM group were significantly higher than those of control group(p<0.05) 4. At 6 weeks. the level of serum cholesterol of 5% HBM group was significantly lower than that of control group. 5. Absolute liver weight of 5% HBM group was significantly lower than that of control group(p<0.05). 6. Minor subaceous sickness of liver cell in the control group appeared but no symptom of liver cell in 5% HBM group. It is concluded that HBM was a safe and effective diet food which aided in inducing weight loss in rat without any observed harmful clinical side effects.

• 환경위생공학
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• 제10권1호
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• pp.106-125
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• 1995

Recently, in accordance with elevation of life style and economics, the public demand became increasingly concerned about drinking water quality. Without an adequate supply of safe water, healthy and comfortable life could not exist. Therefore, the purpose of this study is to provide the guidelines and the basic informations to enable supply of clean, tasty and healthy drinking water acceptable for various demands. We analyzed the quality of tap water, mineral water, purified tap water using home tap water purifier. And we researched on the sense of the public complaint over the tap water. We proposed several items relating to the comfortableness of water quality and the target value. Also we presented a case of water supply system for purity and the points at problem The items and target value are as follows 1. turbidity : not more than 1 degree 2. dry residue : $30~200{\;}mg/{\ell}$ 3. hardness : $10~100mg/{\ell}$ 4. free carbon dioxide : not more than $20mg/{\ell}$ 5. $KMnO_{4}$ consumption not more than $3mg/{\ell}$ 6. odor threshold not abnormal 7. residual chlorine : not more than $0.4mg/{\ell}$ 8. water temperature' not more than $20^{\circ}C$ 9. manganese : not more than $0.01mg/{\ell}$ 10. iron : not more than $0.02mg/{\ell}$ 11. aluminum : not more than $0.1mg/{\ell}$

• 한국자동차공학회논문집
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• 제22권6호
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• pp.68-74
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• 2014

This study analyzes structural stress and fatigue about three types of automotive wheels. As maximum equivalent stresses at 1, 2 and 3 types become lower than the yield stress of material and deformations become minute, theses types are thought be safe on durability. Type 2 model has the most fatigue life among three kinds of types and the rest of models with fatigue lives are shown in the order of type 1 and 3. As the most fatigue frequency of type 2 model happens at the state of average stress and amplitude stress on the stress range narrower than type 1 or 3, type 2 model becomes most stable. In case of type 2 with the state near the average stress of 0 MPa and the amplitude stress of 300MPa, the possibility of maximum damage becomes 30%. This stress state can be shown as the most damage possibility. These study results can be effectively utilized with the design on automotive wheel by anticipating and investigating prevention and durability against its damage.

• 한국학교보건학회지
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• 제26권2호
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• pp.104-113
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• 2013

Purpose: The aim of this study was to investigate prevalence and ecological characteristics of excessive television viewing among elementary school students in Seoul. Methods: Secondary data, representative sample of 11,082 subjects in Seoul was used. After prevalence of the excessive television viewing was identified by using factor analysis, 6 main factors explaining the ecological indicators was founded. After identifying prevalence of the excessive television viewing, by using factor analysis, we found 6 main factors explaining the ecological indicators. After categorizing factors into socio-psychological and lifestyle characteristics, we were investigated the odds ratio of excessive television viewing per characteristics by using multiple logistic regression. Results: The prevalence of excessive television viewing was 29.7% among the elementary school student in Seoul. The prevalence were higher in male, higher grade, and non-South of the Han River. Socio-psychological indicators which expressed excessive television viewing were annoying or bullying, scolding from teacher, depressed mode, thought for a runaway from home, an experience of diet, and negative body image. Life style indicators were a lower intake of fruit and vegetables, a higher intake of Ramyun and soft drink, a worse life style of hand washing, and wearing safety equipment. Conclusion: Lifestyle of television viewing was the comprehensive results from family, school, and society rather than a personal preference. Therefore, it is necessary to educate the hazard of excessive television viewing, to reenforce the students' health competence, to activate a safe leisure program as an alternate of television viewing, and to develop a recommendation.

• 한국인공지능학회지
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• 제4권1호
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• pp.8-10
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• 2016

These days, citizens have a lot of ways to get access to IT. In the past, they tended to neglect IT that was thought to be difficult. But, currently, everyone can manufacture and get access not only software but also hardware when he has an idea. Arduino is used. Rinnai had recently released new product named Smart Sensor Range. Safe consumer who gave priority to the safety made new trend gave attention to fire prevention and smart sensor range. The ones who buy gas range prefer safety to economic advantage and/or fire power. The safety system does not always prevent fire accident. This study makes design and produces alarm that perceives temperature of pot when boiling. Not only temperature sensor but also alarm sensor was used to make alarm of boiling water and to give convenient living life. The arduino can be used at practical life to make products for various kinds of people. The invention can give convenience to housewives at kitchen, children and many persons making use of gas range. Another function can be added to develop. This arduino can develop a lot of products by using the study and other designs.

• The Korean Journal of Physiology and Pharmacology
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• 제22권1호
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• pp.53-61
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• 2018

Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent. In this study, we investigated the effect of ethyl linoleate on the melanogenesis and the mechanism underlying its action on melanogenesis in B16F10 murine melanoma cells. Our results revealed that ethyl linoleate significantly inhibited melanin content and intracellular tyrosinase activity in ${\alpha}$-MSH-induced B16F10 cells, but it did not directly inhibit activity of mushroom tyrosinase. Ethyl linoleate inhibited the expression of microphthalmia-associated transcription factor (MITF), tyrosinase, and tyrosinase related protein 1 (TRP1) in governing melanin pigment synthesis. We observed that ethyl linoleate inhibited phosphorylation of Akt and glycogen synthase kinase $3{\beta}$ ($GSK3{\beta}$) and reduced the level of ${\beta}-catenin$, suggesting that ethyl linoleate inhibits melanogenesis through $Akt/GSK3{\beta}/{\beta}-catenin$ signal pathway. Therefore, we propose that ethyl linoleate may be useful as a safe whitening agent in cosmetic and a potential therapeutic agent for reducing skin hyperpigmentation in clinics.

• Journal of Chest Surgery
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• 제24권3호
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• pp.253-260
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• 1991

The adequacy of anticoagulation with heparin during cardiopulmonary bypass, and precise neutralization with protamine at the conclusion of cardiopulmonary bypass, were important. In sixty children undergoing cardiopulmonary bypass, ACT and heparin dose-response curve were studied. Total dose of heparin before bypass were 2.80$\pm$0.74 mg/kg and the amount of protamine administered after bypass were 3.0$\pm$1.23 mg/kg. So protamine: heparin ratio was 1.07: l.c After administration of protamine which dose is calculated with heparin dose-response curve, ACTs were returned to normal range[mean 114.8 $\pm$13 second]. The heparin sensitivity and its half-life do not have relationship with age, weight, height, surface area and urine amount during operation. And there are too much individual variations in heparin sensitivity and its half-life. So conventional heparin protocols can overestimate or underestimate the amount of heparin and protamine. Heparin dose-response curve makes it possible to maintain anticoagulation in a safe range during bypass with adequate amount of heparin individually. At the conclusion of bypass, this curve can be used to predict the precise amount of protamine amount of protamine needed for neutralization of the heparin. But heparin dose-response curve to be used clinically, further studies will be needed about relationship between ACT and heparin level in the high range, influence of hemodilution and hypothermia to ACT and discrepancy between true adequate amount of protamine and calculated amount by heparin dose-response curve.