• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.4
• /
• pp.2301-2305
• /
• 2016

Background: The early detection of anthracycline- induced cardiotoxicity is very important since it might be useful in prevention of cardiac decompensation. This study was designed with the intent of assessing the usefulness of cardiac troponin T (cTnT) and NT- Pro BNP estimation in early prediction of anthracycline induced cardiotoxicity. Materials and Methods: In this prospective study histologically proven breast cancer patients who were scheduled to receive anthracycline containing combination chemotherapy as a part of multimodality treatment were enrolled. Baseline cardiac evaluation was performed by echocardiography (ECHO) and biomarkers like cardiac troponin T (cTnT) and N terminal- pro brain natriuretic peptide (NT- Pro BNP). All patients underwent cTnT and NT- Pro BNP estimation within 24 hours of each cycle of chemotherapy and were followed up after 6 months of initiation of chemotherapy. Any changes in follow up ECHO were compared to ECHO at baseline and cTnT and NT- Pro BNP levels after each cycle of anthracycline-based chemotherapy. Results: Initial data were obtained for 33 patients. Mean change in left ventricular diastolic diameter (LVDD) within 6 months was $0.154{\pm}0.433cms$ (p value=0.049). Seven out of 33 patients had an increase in biomarker cTnT levels (p value=0.5). A significant change in baseline and follow up LVDD was observed in patients with raised cTnT levels (p value=0.026) whereas no change was seen in ejection fraction (EF) and left atrial diameters (LAD) within 6 months of chemotherapy. NT- Pro BNP levels increased in significant number of patients (p value ${\leq}0.0001$) but no statistically significant change was observed in the ECHO parameters within 6 months. Conclusions: Functional monitoring is a poorly effective method in early estimation of anthracycline induced cardiac dysfunction. Estimation of biomarkers after chemotherapy may allow stratification of patients in various risk groups, thereby opening window for interventional strategies in order to prevent permanent damage to the myocardium.

• Journal of Distribution Science
• /
• v.17 no.4
• /
• pp.77-85
• /
• 2019

Purpose - Statistics of Traditional Market is the only source of information on traditional markets, shopping street, and underground shopping street. The government conducts a survey of traditional market conditions every year to look at the current status of traditional markets and provide effective support. Therefore, this study examines the necessity and validity of updating about the Survey Population of Traditional Market Research design, data, and methodology - This study investigated the necessity of updating about the Survey Population of Traditional Market through literature review. Therefore this study examined the necessity of the current population based on the review of the population related to the sample design, methods, and the sampling frame. Next, we examined the change patterns of the population and the sample by dividing the population and sample of the current survey of the traditional market survey into the market unit, the store unit within the market, and finally the individual store unit. Results - As a result, the population of traditional market changes about 4~6%. Next, the analysis of the store unit in the market shows that the number of stores is very variable even though the market is continuously included in the survey target. Finally, as a result of examining the characteristics of individual stores, the stores with less than one year were more than 6% of the total surveyed stores based on the traditional market. These results are generally inconsistent with the idea that stores in traditional markets will operate for a long time in one place. Next, we proposed the establishment of a management system, applying Citizen Generated Data, and circulation survey. Additionally, this study proposes to change the stratification variables at the regional level rather than the market unit. Conclusions - Therefore, in this study, it is suggested that a current population of traditional market is needed updating, and that a population survey should be updated at least four years. In addition, a system for investigating traditional markets and districts was established and a circulation survey was proposed for efficient use of budgets. Based on these research results and policy suggestions, the future research directions are suggested.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.33 no.3
• /
• pp.230-237
• /
• 2000

An ecological study of the benthic macrofauna was carried out using a modified van Veen grab in September 1997, in Namdaechon estuary, Yangyang, Korea. A total of 17 macro-invertebrates was collected and examined from eleven stations in the study area, including 3,795 individuals and 738.63 g wet weight. Arthropods, annelids and molluscs were most abundant and occupied more than $95{\%}$ of the total number of species, individuals and biomass. Namdaechon estuary in Yangyang was very poor in macrobenthic biodiversity, and numerically dominated and characterized by the polychaetes Heteromastus filiformis, Hediste japonica, Eteone longa, an unidentified oligochaete Oligochaeta sp., a corbulid bivalve Corbicula japonica, and an estuarine isopod Cyathura higoensis. Species composition, species dominance, density, and species evenness were compared among stations. The macrofaunal azoic zone appeared in the bottom of 7 m in depth nearby the artificial bank to catch the salmons to return to the livers for spawning. It probably resulted from the oxygen depletion following strong stratification in summer, which can cause major effect on the ecological conditions and then finally kill bottom macro-invertebrates in this area. Moreover, some opportunistic species thrived in nearby another station and this is of vital importance in terms of the ecological succession in a benthic polluted area.

• Journal of Korean Neurosurgical Society
• /
• v.63 no.6
• /
• pp.827-833
• /
• 2020

Objective : Spine surgery is associated with higher morbidity and mortality rates in elderly patients. The modified Frailty Index (mFI) is an evaluation tool to determine the frailty of an individual and how preoperative status may impact postoperative survival and outcomes. This study aimed to determine the usefulness of mFI in predicting postoperative complications in patients aged ≥75 years undergoing surgery with instrumentation. Methods : We retrospectively reviewed the perioperative course of 137 patients who underwent thoracolumbar-instrumentation spine surgery between 2011 and 2016. The preoperative risk factors were the 11 variables of the mFI, as well as body mass index (kg/㎠), preoperative hemoglobin, platelet, albumin, creatinine, anesthesia time, operation time, estimated blood loss, and transfusion amount. The 60-day occurrences of complication rates were used for outcome assessment. Results : Major complications after spinal instrumentation surgery occurred in 34 of 138 patients (24.6%). The mean mFI score was 0.18±0.12. When we divided patients into a pre-frail group (mFI, 0.09-0.18; n=94) and a frail group (mFI ≥0.27; n=44), only the rate of sepsis was statistically higher in the frail group than in the pre-frail group. There were significantly more major complications in patients with low albumin levels or in patients with infection or who had experienced trauma. The mFI was a more useful predictor of postoperative complications than the American Society of Anesthesiologists physical status score. Conclusion : The mFI can successfully predict postoperative morbidity and mortality in patients aged ≥75 years undergoing spine surgery. The mFI improves perioperative risk stratification that provides important information to assist in the preoperative counselling of patients and their families.

• Journal of Korean Society of Forest Science
• /
• v.87 no.3
• /
• pp.445-458
• /
• 1998

The present study focused on the vegetation structure and dynamics of Betula davurica forest were to provide the information for management, distribution and utilization of B. davurica forest in Mt. Chiri national park, southern Korea. The layer structure of B. davurica forest were consist of tree layer(18 species), middle layer(29 species), shrub layer(43 species) and herb layer(68 species). According to the importance value of stratification of layers, In tree layer, B. davurica dominant the highest value of 123.97%, Alnus hirsuta 49.04., Castanea crenata 25.58%, Quercus serrata 25.02%, Stewartia koreana 14.49%, in middle layer were B. davurica 70.81%, Q. serrata 37.74%, Fraxinus rhynchophylla 25.35% Lindera erythrocarpa 24.52%, S. koreana 18.86%, shrub layer were Sasa borealis 28.28%, L. erythrocarpa 24.94%, Rhus trichocarpa, 20.42%, Stephanandra incisa 19.90% and herb layer Schizandra chinensis 18.51%, Aster scaber 12.26%. Disporum smilacinum 10.63% etc, respectively. Results of chi-square test statistics based on presence-absence parameters, the positively associated species pair were Quercus variablis - Q. acutissima, Stewartia koreana - Symplocos paniculata, Acer pseudo-sieboldianum - Quercus mongolica. And covariation was calculated based on quantitative measure of density. The results showed that the association and covariation values among species not agreed with each other. The frequency distribution of DBH Betula davurica species showed reverse J-shaped, therefore it's seems to retrain as a dominant species. When predicting succession in Betula davurica forest, it is seedling and saplings were not richness, succession was governed by competition of hardwood species of subtree and tree layer.

• Korean Journal of Microbiology
• /
• v.50 no.3
• /
• pp.191-200
• /
• 2014

Gas hydrates play a significant role in the global carbon cycle and climate change because methane, a greenhouse gas, can be released from the dissociation of gas hydrate. Anaerobic oxidation of methane (AOM) is an important process that consumes more than 90% of the methane released into the hydrosphere and atmosphere. In this study, the microbial community associated with the methane gas hydrate sediment in the Ulleung basin, East Sea of Korea (UBGH) was analyzed by phylogenetic analysis of the mcrA and 16S rRNA gene libraries. A vertical stratification of the dominating anaerobic methane oxidizer (ANME)-1 group was observed at the surface and the sulfate methane transition zone (SMTZ). The ANME-2c group was found to be dominant in the high methane layer. The archaea of marine benthic group B, which is commonly observed in the AOM region, accounted for more than 50% of the identifications in all sediments. Nitrate reducing bacteria were predominant at SMTZ (Halomonas: 56.5%) and high methane layer (Achromobacter: 52.6%), while sulfate reducing bacteria were not found in UBGH sediments. These results suggest that the AOM process may be carried out by a syntrophic consortium of ANME and nitrate reducing bacteria in the gas hydrates of the Ulleung Basin of the East Sea.

• Journal of Korean Society of Forest Science
• /
• v.82 no.3
• /
• pp.227-234
• /
• 1993

This study was carried out to seek for a most effective hastening method of seed germination by Pon-Pon treatment and asexual multiplication method by cutting in Zanthozylum piperitum. The results obtained in this study were as follows : 1. Cold moist stratification under the ground accompanied with Pon-Pon treatment was shown 74.3% of seed germination, which was the most effective one among pretreatment methods with significance at 1% level. 2. Height growth was shown continuous growth pattern and the maximum growth was shown during the period 1 July to 31 July, which corresponds 40.3% of total annual growth. 3. Although no noticeable difference among the kind of plant growth regulator in the rooting rate, there was difference among concentrations with significance at 1% level. 4. In the case of number of primary roots and T/R rate of rooted cuttings, treatment of plant growth regulators was significantly superior to control. 5. T/R rate in rooted cuttings was a high negative correlation (r=-0.7164) with the number of primary roots.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.24 no.6
• /
• pp.390-399
• /
• 2012

This research observed the cross section current of 7 survey lines in Seokmo Channel of Gyeonggi bay with a lot of freshwater inflow and S-shaped for 13 hours during flood season and neap tide. We indicated the distribution of the current velocity by comprehending the speed and direction of the current velocity of each line during maximum flood, ebb tide and observed the distribution of salinity. Moreover, in order to understand what lateral momentum causes the lateral flow in each survey line, we practiced the momentum analysis through the observation data. As a result, the lateral baroclinic pressure gradient force and vertical friction of the Seokmo channel during neap tide were the strongest, and this is why the flow by the distribution of salinity and stratification most often occurs. In north of the Seokmo channel, where have wide intertidal and a lot of freshwater inflow, the secondary circulation is caused by balance of lateral baroclinic pressure gradient force and other forces, and the vertical friction was strong in the lines with small depth. On the other hand, in the southern part of the Seokmo channel where the water is deep and the waterway is curved, the advective acceleration and centrifugal force become stronger by the geographical causes during ebb and the influence of fresh water. Therefore, the lateral flow in the Seokmo channel was caused by the distribution of the momentum that differs by location, depth, curve, etc.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.17
• /
• pp.135-142
• /
• 1974

A study on the metabolism of the chemical companents of endosperm and enbryonic othans of ginseng seeds during their germination were inverstigated and the results of the changes in the contents of nitrogen conponds, carbohydrates, lipids and phosphorus conpounds are summarized as follow; 1. When a seeding grows to 5cm the fresh weight of the embryonic organ incerases 13 times compared with that of its ripened embryo veore germination and its dry weight increases 4.5 times. On the other hand, about 65% of the dry weight of the endosperm is lost. 2. During germinarion the total nitrogen content of a sedding (endosperm+embryonic organ) decreases and when the seeding grows to 5cm there is a loss of 10% of total nitrogen content. At this time, soluble nitrogen content amounts to 40~50% of the total nitrogen, a comparatively high content. 3. When theseeding grows to 5cm, the total phosphorus content decreases by 15%. During the germination period 70~75% of the total phosphorus is distributed in the embryonic orang and 25% of it is in endosperm.In the embryonic organ 35~50% of the acid soluble phosphorus is inorganic phosphorus and in the endisperm, 20~25% of the acid soluble phosphorus is inorganic phosphorus,75~80% of the organic phosphorus is contained in the endosperm. 4.One the seedling grew to 2~3cm, carbohydrates such as soluble sugars,reducong sugars,nonreducong sugars, and crude starch interconverted remarkably. 5.After stratification (just before germination) the lipid content of the endosperm is about 54% of the total weight and lipid content of the embryo is about 61%. During germination 6.81mg of the fat contained in the endosperm per seed decreases to 4.13mg while the change of fat content in the embryonic organ is not so great.

• The Journal of the Korea Contents Association
• /
• v.15 no.12
• /
• pp.61-72
• /
• 2015

The capitalistic resistance movement attempted in most modern art areas was carried out through a complete convergence of the art and skill, which was the new formation of the symbolic boundary. Although this resistance movement was aimed at restoring artisan art through the revival of tbe work of handicraftsmen, it consequently caused the stratification of the art and became a de-artisan art excluding the autonomous labor. Hereupon, this study would focus on Bauhaus which attempted to dismantle the symbolic boundary through the convergence of the technology and art which actively used the condition the great industry brought only as an effort for the restoration of artisan labor, and would examine the actor-network of Bauhaus. Therefore, this study would examine the Bauhaus' artistic trend, the 16C Renaissance art promotion movement, and the 19C art crafts movement in the network-oriented relation, and would analyze the Bauhaus' ideological source which expressed design democracy through the bridging role of and analyze the artisan art and the mechanism that had the new technology fused. Furthermore, the convergence possibility of the 'collaboration spirit' being embodied as a philosophy of the democracy in the design continues with the tremendous influence of the new technology.