• World Technopolis Review
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• 제2권1호
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• pp.32-42
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• 2013

Science and Technology Park (STP) is perceived to be a vehicle in promoting innovation-based economic growth within the framework of regional and national innovation systems. STP is a tool to encourage regional innovation and competitiveness in increasing contribution of science and technology in economic development. STP can also be a leading sector in creating conducive environment for local community's technopreneurship. In relation to the vision outlined in the 2025 Indonesian Master Plan of Acceleration and Expansion of Indonesia's Economic (MP3EI), STP is stated to be an important element in creating innovation within the framework of Special Economic Zone among six Economic Corridors. Hence, the government of Indonesia continues to encourage the development of STPs in Indonesia by involving local governments, universities, business players and stakeholders surround the area. Ultimately, STP is a platform in developing National Innovation System (NIS) and Regional Innovation System (RIS).

• BMB Reports
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• 제40권3호
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• pp.341-348
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• 2007

Herpesvirus saimiri (HVS), a member of the $\delta$-herpesvirus family, encodes an oncoprotein called Saimiri Transforming Protein (STP) which is required for lymphoma induction in non-human primates. Previous study has shown that STP-C, an oncoprotein of HVS, activates NF-$\kappa$B signaling pathway. However, the detailed mechanism of STP-Cmediated NF-$\kappa$B activation has not been reported yet. We first report that STP-C interacts with TRAF6 protein in vivo and in vitro and further investigation shows that $Glu_{12}$ residue of STP-C is critical for binding to TRAF6. Introduction of ubiquitin together with STP-C augments NF-$\kappa$B activity compared to that of STP-C expression alone. STP-C expression further induces ubiquitination of endogenous TRAF6. In addition, either a deubiquitination enzyme, CYLD or a dominant negative E2-conjugation enzyme reduced NF-$\kappa$B activity in spite of the presence of STP-C, supporting that the interaction between STP-C and TRAF6 induces ubiquitination of TRAF6. NF-$\kappa$B activation by STP-C through the ubiquitinated TRAF6 causes the increased production of IL-8, an inflammatory chemokine and the enhanced expression of costimulatory molecule ICAM, which might ultimately contribute cellular transformation by the exposure of HVS-infected cells with inflammatory microenvironment and chronic activation.

• World Technopolis Review
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• 제3권3호
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• pp.114-121
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• 2014

This paper presents two cases of Science and Technology Parks (STPs), from Malaysia and India, that are driven by business organisations in partnership with governments. The need to locate the STP near to a university or a research institute has been considered crucial to attract firms to the STP - but in this paper, we illustrate the efforts to develop a locally relevant STP through the cases of Pahang Bio Science in Malaysia and the ICICI Knowledge Park (now known as IKP) in Hyderabad India. These two developments are anchored by business organisations that are playing a pivotal role in their development. The government plays a supporting role in terms of policy and supplying certain complementary resources. In addition, we note that the government support also provides legitimacy for the business organisation developing the STP. In the case of the Malaysian STP, we note the approach is towards inclusive development by developing linkages to local communities, and in the case of the Indian STP, one can see the development of the STP in a dynamic way changing according to the needs of the sector. Especially interesting is the foresight by the nodal business organisations in developing the STPs.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2011년도 춘계학술발표대회
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• pp.572-575
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• 2011

It is well known that spanning tree protocol (STP) is the most commonly used protocol in switching networks for smart grid. STP selectively blocks redundancy links of the network to prevent layer 2 loops in network, and it also has a functionality of backing up links. As with the other protocols, STP has been updated with the continuing development of the network. STP is a broad concept and it does not just refer in particular to defined STP protocol in IEEE 802.1D standards, it refers to updated spanning tree protocol based on STP. Because of uneven distribution of communication traffic in root bridge, STP cannot satisfy fast converge nce while the failure occurs near the root bridge or on the root bridge in tree topologies of STP. In this paper, we propose a novel method --- Hyper Cube Spanning Tree Protocol (HCSTP) to solve uneven distribution of communication traffic. Theoretically, hyper cube in our protocol increases throughput and improves the utilization of communication. The simulation results show that HCSTP can achieve comparative and considerably higher performance than other STP protocols in terms of reconnection.

• World Technopolis Review
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• 제5권1호
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• pp.30-46
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• 2016

This paper is intended as an opening of a dialog on how to apply platform thinking in the development of innovation environments. It will briefly describe a new STP (Science and Technology Park) concept called 3GSP (Third Generation Science Park), which is gaining momentum in Finland. The paper explains the fundamental changes that are currently taking place in the global innovation environment and explains why platform thinking is becoming an essential element in ecosystem development. The theoretical background and classifications of platforms are described and the benefits to be gained from STP perspective are highlighted. The paper emphasizes especially the role of so called 'competence platforms' and explains the main characteristics of a fully working competence platform. The role of competence platforms in understanding serendipity and as a fundamental factor in building the team is also highlighted. The paper analyses from STP perspective several practical examples, where platform thinking supports the emergence of new innovation environments, including Urban Mill (Finland) and Meetberlage (Netherlands). The requirements for comprehensive competence platform services are presented and their potential to support community building and therefore ecosystem development is illustrated. This analysis will provide STP practitioners with new models for applying platform thinking and will help to establish co-creation, open innovation and serendipity management practices. The case studies presented will help STP management teams to evaluate the benefits of competence platforms in different contexts.

• 벤처창업연구
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• 제7권4호
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• pp.131-141
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• 2012

우리나라의 단기간 내 급성장은 많은 개발도상국의 벤치마킹 대상이 되고 있다. 이 가운데 과학기술분야의 과학기술단지(STP) 경험은 각국이 도입하기 위해 노력중이다. 자원강대국인 에콰도르와 카자흐스탄은 ODA 협력대상국으로 대덕특구의 STP 모형을 벤치마킹 중에 있다. 이 들 두 국가의 요구를 파악하고, 우리가 제공 가능한 요인은 무엇인지, 그리고 어떻게 이를 효과적으로 실천에 옮길 수 있는가를 파악하고자 한다. 본 논문은 현지국에 STP를 건립하는데 대덕특구의 건립 및 운영경험을 토대로 여섯 가지 제안을 하고 있다. 첫째, 인적자원 확보 전략이다. 개발도상국에서 필요한 것은 지식과 기술이며 이 지식과 기술은 사람에 체화된 지식이므로 인적자원의 확보가 급선무이다. 둘째, 산학협력의 엔지니어링 센터의 설립이다. 기술을 습득하고 협상력을 갖기 위해 각 분야별 기술엔지니어링 센터를 설립한다. 셋째, 기술 사업화에 필요한 하드웨어와 소프트웨어의 확보이다. 기술사업화에 필요한 공간 등의 보육시설과 함께 컨설팅 서비스를 수행할 보육매니저, 보완자산 등이 필요하다. 넷째, 시장과의 연계노력이다. 개발도상국의 STP의 완성은 기업의 탄생과 성장 및 연계에 있다. 다섯째, 사이언스 파크 등의 설립을 통해 클러스터링 효과를 극대화하도록 하는 것이다. 여섯째, 흡수능력을 향상시키는 리더십의 구축이다.

• 대한의생명과학회지
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• 제25권4호
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• pp.390-397
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• 2019

High risk-human papillomavirus (HR-HPV) is known to be a major cause of cervical cancer, and coinfection of sexually transmitted pathogen (STP) has been reported to cause persistent HPV infection. However, the relationship between HPV and STP coinfection remains unclear. The purpose of this study was to analyze the coinfection rate with STP in high-risk human papillomavirus infected women in Busan and to collect basic data for the prevention of cervical lesions. This study was carried out in 355 women who had concurrent HPV and STP screening at Busan local hospital between January 2016 and December 2017. HPV and STP coinfection was found in 187 (52.7%) out of 355 cases. HR-HPV and STP coinfection was 82.9% higher than LR-HPV and STP coinfections 17.1%. In HR-HPV infection, Ureaplasma species was the most common pathogen (47.1%), followed by C. trachomatis (21.9%) and Mycoplasma species (12.3%). In the analysis of HR-HPV genotype according to STP, HPV 16 (12.0%) was the most frequent, followed by HPV 58 (11.6%), HPV 39 (11.1%) and HPV 52 (10.2%), but HPV 18 showed a low coinfection rate of 1.3%. According to the results of age, HR-HPV and STP coinfection rate was the highest at 41.9% among women aged 18 to 29. HR-HPV and Ureaplasma species showed the highest coinfection rates at all ages, followed by C. trachomatis and Mycoplasma species. Further studies with more samples will be needed to determine if the coinfection of HR-HPV and STPs is involved in the development of cervical tumors through histologic changes.

• 대한조선학회 특별논문집
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• 대한조선학회 2009년도 특별논문집
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• pp.24-34
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• 2009

The latest trend of development for submarine oil field is caused by the drained oil and gas for ground field, and FPSO is a keyword as the development for submarine oil field. FPSO (Floating Production Storage Offloading) is a kind of vessel type have a topside system for production of oil and gas and store them until the oil or gas can be offloaded onto a tanker or transported through a pipeline. Prior to the introduction of reinforcement under the pull-in winch on the STP extended top as the object of this paper, the technical background shall be introduced such as FPSO and the system and main equipments for STP as follows. The original structural concept for reinforcement of pull-in winch on the STP top and extended structure on moonpool was proposed by buyer's engineering team but it was much modified and improved in accordance with builder's fabrication and construction method.

• World Technopolis Review
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• 제1권1호
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• pp.56-64
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• 2012

This paper provides a case study to explore the Kitakyushu case as a good referential example on STP development for rejuvenation of declining industrial city. The major data for the case, basically, has been sourced from some materials published by the municipality of Kitakyushu City, the website of the Kitakyushu Science and Research Park (KSRP) etc. The City of Kitakyushu has promoted the KSRP development to overcome industrial decline and stimulate city renaissance as a new industrial city. The core of the development was to develop a high-level education and research environment by gathering several HEIs into one campus. Based on the environment, the Kitakyushu Foundation for the Advancement of Industry and Science and Technology (FAIS) played the critical role as a coupler to make various networks and boost industry-academiaadministration innovation. The KSRP, and then, has been designated as a project area of some cluster projects initiated by the central government. It means that local projects can be synchronized, synergized and synthesized with national projects in the KSRP. In addition, through a series of the environmental approach from the Kitakyushu Eco-town Project to the Low Carbon Society Project, the development of the KSRP is being extended into the region. In the Kitakyushu case, networking is the essence of the KSRP development from the planning stage. First of all, the plan put emphasis on networking of academia for the knowledge creation based on competitive collaboration that is expected as the mainspring of rejuvenating declining industrial area and making a new industrial city that the plan aimed. Then, the roles of two organizations are very important for networking, especially networking of networks: the Campus Management Committee as an interface and the FAIS as a coupler. STP development without some strategic considerations for networking as the way of interaction among its participants cannot be a tool to promote innovation and rejuvenate a declining industrial area. The Kitakyushu case mentioned above explains the matter clearly.

• 한국물환경학회지
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• 제25권5호
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• pp.778-784
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• 2009

The purpose of this study is to figure out the differences of the inflow rates of Sewage Treatment Plants (STP), invested by public fund or public-private partnership (PPP). This paper finds that the average ratio of sewage inflow according to facility capacities (medium and small scale STP) was either nearly below 30% or above 100% in the first year. As the size of STP increased, there was decrease in the accuracy of demand assumption. This was because the operation time when the ratio of sewage inflow was uniform was different according to the size of STP, whereby the time was short when the STP were small. The design average ratio of sewage inflow was 10% larger than the real average ratio; this was considered overdesigned. In the case of a plant built by the PPP scheme, the average ratio of inflow of the STP before an abolition of MRG was larger than after the abolition of MRG. This may be explained by moral hazard from too much reliance on MRG. After the abolition of MRG, the demand risk of PPP was shifted from a PPP project to a conventional project.