• Journal of Food Hygiene and Safety
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• v.34 no.1
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• pp.87-93
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• 2019

Revision work on the Codex Classification of Foods and Animal Feeds was undertaken in 2007 and presently, revisions for most food groups have been completed. For vegetables, the work was conducted during 2014-2017, and the final draft revision was adopted by the $40^{th}$ Codex Alimentarius Commission (2017). Here, the revised classification of vegetable commodities is introduced in order to be utilized in various food-related fields, in particular, food safety regulation. The revised classification is briefly summarized as follows: Codex classified vegetables into 10 groups (Group 009-018): bulb vegetables (Group 009), Brassica vegetables (except Brassica leafy vegetables) (Group 010), fruiting vegetables, Cucurbits (Group 011), fruiting vegetables, other than Cucurbits (Group 012), leafy vegetables (including Brassica leafy vegetables) (Group 013), legume vegetables (Group 014), pulses (Group 015), root and tuber vegetables (Group 016), stalk and stem vegetables (Group 017) and edible fungi (Group 018). The groups are further divided into a total of 33 subgroups. In the Classification, 430 different commodity codes are assigned to vegetable commodities. Meanwhile, Korea's Ministry of Food and Drug Safety (MFDS) does not include potatoes, beans and mushrooms within a vegetable group. In addition, the MFDS divides one vegetable group into six subgroups including flowerhead Brassicas, leafy vegetables, stalk and stem vegetables, root and tuber vegetables, fruiting vegetables, Cucurbits, and fruiting vegetables other than Cucurbits. Therefore, care is needed in using the Codex Classification.

• Journal of Life Science
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• v.34 no.5
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• pp.339-355
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• 2024

The pulmonary system is a highly complex system that can only be understood by integrating its functional and structural aspects. Hence, in vivo animal models are generally used for pathological studies of pulmonary diseases and the evaluation of inhalation toxicity. However, to reduce the number of animals used in experimentation and with the consideration of animal welfare, alternative methods have been extensively developed. Notably, the Organization for Economic Co-operation and Development (OECD) and the United States Environmental Protection Agency (USEPA) have agreed to prohibit animal testing after 2030. Therefore, the latest advances in biotechnology are revolutionizing the approach to developing in vitro inhalation models. For example, lung organ-on-a-chip (OoC) and organoid models have been intensively studied alongside advancements in three-dimensional (3D) bioprinting and microfluidic systems. These modeling systems can more precisely imitate the complex biological environment compared to traditional in vivo animal experiments. This review paper addresses multiple aspects of the recent in vitro modeling systems of lung OoC and organoids. It includes discussions on the use of endothelial cells, epithelial cells, and fibroblasts composed of lung alveoli generated from pluripotent stem cells or cancer cells. Moreover, it covers lung air-liquid interface (ALI) systems, transwell membrane materials, and in silico models using artificial intelligence (AI) for the establishment and evaluation of in vitro pulmonary systems.

• The Journal of Bigdata
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• v.4 no.1
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• pp.53-61
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• 2019

The extracellular matrix, which provides the structural and biochemical support of surrounding cells, is a cell physiological modulator that controls cell division and differentiation. In the bio sector, the company produces Scapold, a three-dimensional support for tissue engineering, and cultivates stem cells in the produced Scapold to be transplanted into animals to assess tissue regeneration. This depends on components such as collagen in the tissue. Therefore, it is very important to identify the inclusion rate and distribution of components in the tissue, and the data are obtained by analyzing the color of the dyed tissue image. The process from image collection to analysis is costly, and the data collected and analyzed are managed in different formats by different research institutions. Therefore, data integration management and analysis results search are not being performed. In this paper, we establish a database that can manage relevant bigdata in an integrated manner, and propose a bio-image integrated management and retrieval system that can be searched based on color, an important analytical measure in this field of study.

• Journal of Fisheries and Marine Sciences Education
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• v.25 no.4
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• pp.915-927
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• 2013

This study aimed to discover the affective ability of students by applying a thematic project model concerning the marine field unit of science for third grade middle school students from among diverse methods of realizing STEAM education. Also, based on this, STEAM education is a new type of learning including the process of exploring by oneself, presenting, discussing and mutually evaluating by becoming an independent person in learning As the results of the study are as follows: First, the STEAM class applied with a thematic project model was discovered to promote a learning attitude toward science by learners. Second, the STEAM class applied with a thematic project model was shown to be effective in improving the self-directed learning characteristics of learners. Third, STEAM education applied with a thematic project model was found to promote learners' motivation for learning science. This may be an effective method for learners who have felt difficulty in the science curriculum or have not been interested in the curriculum by triggering voluntary motivation.

• Proceedings of the Materials Research Society of Korea Conference
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• 2010.05a
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• pp.42.1-42.1
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• 2010

Poly-carprolactone (PCL)은 생분해성 고분자로 장기간의 임상실험 결과 생체에 독성이 없으며 생체친화성이 우수한 소재로 확인되어 PLGA, PLLA 등과 더불어 조직공학 분야에서 널리 사용되고 있는 생체재료이다. 그러나 PCL은 5개의 비극성 methylene group과 1개의 극성 ester group이 반복되는 지방족의 polyester로 구조상 탄소수가 많아 소수성을 띄는 단점을 가지고 있다. 이러한 표면이 소수성인 재료의 경우, 초기 단백질 흡착능이 떨어져 세포의 부착이 느린 속도로 일어나므로 세포 분화 및 조직 재생이 더디게 일어난다. 본 연구에서는 소수성의 PCL 표면의 단백질 흡착능을 증가시키기 위해 기능성 amine group을 부착하였으며, 또한 골재생을 촉진시킬 수 있는 세포외 기질인 collagen과 osteopontin을 부착함으로써 고기능성 PCL membrane을 제조하였다. 제조된 PCL membrane은 골재생용 조직공학에의 응용을 위해 지방유래 줄기세포를 이용하여 부착능 및 골세포로의 분화능을 확인하였다. 표면 성질의 변화에 의한 세포의 부착능의 변화를 confocal microscopy을 이용하여 부착에 관여하는 단백질의 발현을 확인하였으며, collagen과 osteopontin에 의한 골세포로의 분화능을 확인하기 위해 real time PCR을 통해 골세포의 분화 표지 유전자의 발현을 비교 분석하였다.

• The Korean Journal of Applied Statistics
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• v.26 no.3
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• pp.421-429
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• 2013

Modern statistics is used in many fields; however many users face difficulties in understanding statistical concepts. On the other hand, elementary school curriculum covers stem and leaf plot, pie chart, charts for proportional data as well as descriptive statistics including the mean. We find that an "intuitive" statistical package focused on 5-8 graders for statistical education will help future statistics users understand statistical concepts at earlier stages of their lives.

• Water for future
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• v.19 no.2
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• pp.167-180
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• 1986

Disaggregation model has recently become a major technique in the field of synthetic generation and the model is possibly one of the most widely acepted tools in stochastic hydrology. The application of disaggregation model is evaluated with the streamflow data at the Waegwan and Hyunpung stage gaugin station on the main stem of the Nakdong River. The disaggregation process of annual streamflow data and the method of parameter estimation for the model is reviewed and the statistical analysis of the generated monthly streamflows such as a computation of moment estimation of covariance and correlogram analysis is made. The results, disaggregated monthly streamflow, obtained by Disaggregation Basic Model for single site are compared with the historical streamflow data and also with the other model, Thomas-Fiering Model. The generated monthly streamflow data by two models have been investigated and verified by comparision of mean and standard deviation between the historical and generated data.

• Journal of Life Science
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• v.14 no.4
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• pp.716-725
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• 2004

Sox protein family, a transcription factor, has been found in whole animal kingdom, and contains a sequence-specific DNA binding domain called high mobility group domain (HMG). The Sox protein family based on the amino acid sequence of HMG domain was classified into 10 groups. Each group of Sox family shows significant conservation from nematode to human. The HMG domain affect to various developmental cell differentiation through binding to enhancer and regulating other transcription factors. Recently, many molecular biologists focus their research on the illustration of Sox-related disease, evolution and phylogeny. Especially, stem cell research with Sox gene family is indispensable field for understanding of their biological functions. The understanding of Sox genes may contribute to understand their role in human genetic disease and whole animal evolution.

• Journal of the Korean Operations Research and Management Science Society
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• v.40 no.4
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• pp.49-63
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• 2015

Keyword indexed in multidisciplinary journals show trends about science and technology innovation. Nature and Science were selected as multidisciplinary journals for our analysis. In order to reduce the effect of plurality of keyword, stemming algorithm were implemented. After this process, we fitted growth curve of keyword (stem) following bass model, which is a well-known model in diffusion process. Bass model is useful for expressing growth pattern by assuming innovative and imitative activities in innovation spreading. In addition, we construct keyword co-occurrence network and calculate network measures such as centrality indices and local clustering coefficient. Based on network metrics and yearly frequency of keyword, time series analysis was conducted for obtaining statistical causality between these measures. For some cases, local clustering coefficient seems to Granger-cause yearly frequency of keyword. We expect that local clustering coefficient could be a supportive indicator of emerging science and technology.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.05a
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• pp.404-406
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• 2016

Due to the localization process of offshore drilling system, ensuring safety has emerged as an important. Therefore, step by stem safety analysis about each development process of offshore drilling system is becoming compulsory. Hazard and operability analysis is a method that was successfully used for system safety analysis in industries such as chemical plants. Through this hazard and operability analysis study, to conduct step by step safety analysis accorsing to process, the study conducted hazard and operability analysis in Lp mud system, an area of offshore drilling system.