• 대한한의학방제학회지
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• 제31권2호
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• pp.99-109
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• 2023

Objectives : Sihosogan-tang (SST) is one of the traditional herbal formula and also one of the Korean medical insurance medicines. It commonly used in the treatment of hepatitis, chronic gastritis, intercostal neuralgia, pleurisy, and depression in East Asia. In the present study, we have demonstrated the anti-inflammatory effects of SST in macrophage cell line. Methods : To investigate mechanism of the anti-inflammatory effect of SST, we examined the productions of nitric oxide (NO) and pro-inflammatory cytokines, and the expressions of inducible NO synthase (iNOS), nuclear factor-κ B (NF-κB) and mitogen-activated protein kinase (MAPK) on RAW 264.7 cells activated by LPS. Results : SST significantly inhibited the expression of iNOS increased by LPS, and also significantly inhibited the production of NO. In addition, SST significantly inhibited pro-inflammatory cytokines such as TNF- α and interleukines. SST inhibited the expression of NF-κB and MAPK activation. Conclusions : These results suggest that SST ameliorates inflammatory response in LPS-activated RAW 264.7 cells through the inhibition of the NF-κB and MAPK pathway. Therefore, this study supplies objective evidence for the anti-inflammatory effect of SST.

• The Journal of Korean Physical Therapy
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• 제27권5호
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• pp.332-338
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• 2015

Purpose: The purpose of this study was to examine the effect of postural control and locomotion on improvement of two point discrimination (TPD), stereognosis (ST) through somatosensory training (SST) on the upper limb (UL). Methods: The subjects were 20 hemiplegia patients who have problems with unilateral neglect after stroke. The patients were divided into two groups, the experimental group (EG) and the control group (CG). In the EG, SST for TPD, ST was performed 18 times, three times a week for six weeks, together with physical therapy (PT) and occupational therapy (OT). In the CG conventional PT and OT without SST was performed for six weeks. Several assessment tools were used in comparison of groups; two point discrimination test (TPDT) on forearm (F), thenar (T), hypothenar (TH), thumb tip (TH-T), index finger tip (IN-T), stereognosis test (ST), postural assessment scale for stroke (PASS), and clinical test of sensory interaction on balance (CTSIB) and timed up and go test (TUG). Results: In the CG, conventional PT and OT resulted in statistically improved TPDT (F), ST, PASS, and TUG. In the EG, SST resulted in statistically improved TPDT (F, T, HT, TH-T, IN-T), ST, PASS, and TUG. TPDT-T, ST, and CTSIB with length of displacement with eye open (LDEO) also showed significant improvement between the groups. Conclusion: In both groups TPDT ST, PASS and TUG, and SST had effects on the UL and TPDT, ST and static postural control had greater effects compared with the PG. Therefore, we could assume that TPD and ST are very important in performing human activities including postural control and locomotion.

• 대한한의학방제학회지
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• 제21권2호
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• pp.44-52
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• 2013

Objectives : Samhwangsasim-tang (SST), Hwangryeonhaedok-tang (HHT), Ukgan-san (UGS), Onjunghwadam-hwan (OHH) and Samul-tang (SMT) have been used for the treatment of various diseases. This study was performed to compare the anti-obesity effects of 5 herbal formulas in high fat diet-(HFD) induced obese mice. Methods : The mice were randomly divided into seven groups that were fed a normal diet (ND), a HFD, a HFD plus SST (HFD + SST), a HFD plus HHT (HFD + HHT), a HFD plus UGS (HFD + UGS), a HFD plus OHH (HFD + OHH), or HFD plus SMT (HFD + SMT) at 300 mg/kg/day for 7 weeks. All groups were assayed for body weights, food efficiency ratio (FER), final liver and fat weight and blood biochemical parameters. Results : The increased body weights, food efficiency ratio (FER), and serum total triglyceride were decreased in HFD + OHH group relative to the same measurements in HFD group. Furthermore, the HFD + SST group significantly reduced FER, liver and abdominal subcutaneous fat weight gains, and serum total triglyceride, whereas HDL-cholesterol level was increased compared to HFD group. Conclusions : These results suggested that HFD + OHH and HFD + SST exert anti-obesity effects in HFD-induced obese mice.

• 한국해양학회지:바다
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• 제24권4호
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• pp.509-518
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• 2019

다양한 표층 수온 자료를 통해 1979년부터 2018년 기간 동안의 가을철 동해 공간 평균 표층 수온이 태평양 순년 진동과 높은 상관관계를 나타내는 것을 확인하였다. 이 해역에서 제트류의 활동이 가장 강한 200 hPa에서의 바람과 동해 표층 수온의 회귀 분석 결과, 가을철 동해 표층 수온이 상승할 때 제트류의 중심축이 북상하면서 전반적으로 제트류가 약화하는 경향을 보이며, 동해 수온이 하강할 때는 제트류의 중심축이 남하하면서 제트류가 강화되는 경향을 보였다. 이러한 분석 결과는 제트류의 강도 변화와 중심축의 남북 진동이 동해 표층 수온과 태평양 순년 진동의 커플링과 관련되어 있음을 시사한다. 여름철의 약한 제트류와 겨울철 및 이른 봄철의 강한 동아시아 동계계절풍 효과는 동해와 태평양 순년 진동의 커플링이 가을철 외의 다른 계절에 잘 나타나지 않게 하는 이유로 생각해볼 수 있다.

• Ocean and Polar Research
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• 제34권2호
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• pp.201-218
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• 2012

The purpose of this study is to investigate climatological variations from the sea surface temperature (SST), chlorophyll-a concentration (Chl-a), and phytoplankton size class (PSC), using NOAA AVHRR, SeaWiFS, and MODIS data in the South Sea of Korea (SSK) and East China Sea (ECS). 26-year monthly SST and 13-year monthly Chl-a and PSC data, separated by whole and nine-different areas, were used to understand seasonal and inter-annual variations. SST and Chl-a clearly showed seasonal variations: higher SST and Chl-a were observed during the summer and spring, and lower values occurred during the winter and summer. The annual and monthly SST over 26 years increased by $0.2{\sim}1.0^{\circ}C$. The annual and monthly Chl-a concentration over 13 years decreased by $0.2{\sim}1.1mg/m^3$. To determine more detailed spatial and temporal variations, we used the combined data with monthly SST, Chl-a, and PSC. Between 1998 and 2010, the inter-annual trend of Chl-a decreased, with decreasing micro- and nano-size plankton, and increasing pico-size plankton. In regional analysis, the west region of the study area was spatially and temporally correlated with the area dominated by decreasing micro-size plankton; while the east region was less sensitive to coastal and land effects, and was dominated by increasing pico-size plankton. This phenomenon is better related to one or more forcing factors: the increased stratification of ocean driven by changes occurring in spatial variations of the SST caused limited contributions of nutrients and changed marine ecosystems in the study area.

• 한국의류학회지
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• 제43권5호
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• pp.634-648
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• 2019

Self-service technologies (SST) are rapidly changing the way customers participate in the purchasing process. Academic literature has focused on the acceptance of SSTs. However, this study explored consumer's cognitive response and purchase intentions through service qualities of SST as well as how they are moderated by technology anxiety and other people's presence based on TAM3. An online survey collected 279 consumer panels. All responses were used for the analysis and analyzed statistically through SPSS 23.0. The results indicate that only enjoyment and control had a significant effect on warmth perception; however, all service qualities had significant effects on competence perception. The perceived warmth and perceived competence partially mediated the relationship between SST service qualities and purchase intention. The moderating effect of technical anxiety was shown to be significant in the relationship between perceived competence and purchase intention. In addition, technology anxiety had a moderating effect on the relationship between competence perception and purchase intention only in a public situation.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제24권4호
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• pp.199-206
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• 2013

Objectives : Attention-deficit hyperactivity disorder (ADHD) and Asperger's disorder (AD) in children are associated with attentional problems, impulsivity, hyperactivity, and difficulties with social interactions. Pharmacological treatment may alleviate symptoms of ADHD, but seldom solves difficulties with social interactions. Social skills training (SST) may assist in improving their social interactions. We examined the effects of SST on children's social competences, general behavior, and ADHD symptoms. Methods : Thirty four children, aged 7 to 12 years, participated in the cognitive behavioral SST program once a week at the outpatient division of child-adolescent psychiatry. SST was composed of 24 sessions (ninety minutes) for 6 months. Twenty-five children were diagnosed with ADHD, and 9 children were diagnosed with AD. Parents of the children rated Korea-Child Behavior Checklist (K-CBCL), Conner's rating scales, Korean-ADHD Rating Scale (K-ARS), Social Skill Rating System (SSRS), and Matson's Social Skill Rating Scale as an evaluation of the treatment effect, before the first session and after the final session of the training. Results : The ADHD group showed significantly increased scores of social and social competence of CBCL and SSRS. Further, scores of externalizing problems of CBCL, CRS, and ARS were significantly decreased. The Asperger's group showed significantly increased scores of social competence of CBCL, SSRS, and MESS. There was a significant difference of the improvement in CBCL's school and total behavior problem score, CRS between drug change group and no drug change group. Conclusion : The result of this study suggests that SST is effective in improving social skills for children with ADHD and AD. In addition, SST has shown its effectiveness in treating attentional problems for children with ADHD. To prove objective usefulness of SST, further studies with a more structured design and long-term duration along with a sufficient number of AD participants will be necessary.

• Ocean and Polar Research
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• 제42권3호
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• pp.179-194
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• 2020

The present study aims to evaluate the effects of satellite-based SST (OSTIA) assimilation on a regional ocean circulation model for the Yellow and East China Seas (YECS), using three different assimilation methods: the Ensemble Optimal Interpolation (EnOI), Ensemble Kalman Filter (EnKF), and 4-Dimensional Variational (4DVAR) techniques, which are widely used in the ocean modeling communities. The model experiments show that an improved initial condition by assimilating the SST affects the seasonal water temperature and water mass distributions of the YECS. In particular, the SST data assimilation influences the temperature structures horizontally and vertically in winter, thereby improving the behavior of the YS warm current water. This is due to the fact that during wintertime the water column is well mixed, which is directly updated by the SST assimilation. The model comparisons indicate that the SST assimilation can improve the model performance in resolving the subsurface structures in wintertime, but has a relatively small impact in summertime due to the strong stratification. The differences among the different assimilation experiments are obvious when the SST was sharply changed due to a typhoon passage. Overall, the EnKF and 4DVAR show better agreement with the observations than the EnOI. The relatively low performance of EnOI under storm conditions may be related with a limitation of EnOI method whereby an analysis is obtained from a number of climatological fields, and thus the typhoon-induced SST changes in short-time scales may not be adequately reflected in the data assimilation.

• 대한원격탐사학회지
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• 제34권6_1호
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• pp.953-968
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• 2018

본 연구는 동중국해에서 표층수온의 변화를 이해하기 위해 2003년부터 2017년까지 15년 동안의 위성 및 모델 재분석 자료를 사용하여 수온, 기온, 그리고 열속의 관계를 분석하였다. 동중국해의 표층수온은 3월에 최저(평균 $13.72^{\circ}C$)를 보이고, 8월에 최고(평균 $28.12^{\circ}C$)를 나타내는 계절적 변화를 보였다. 기온은 표층수온의 계절적 변화와 높은 상관관계를 가지고 있으며 유사한 변화를 나타낸다. 표층수온이 가장 높아지는 8월의 경우 표층수온과 기온의 차이가 줄어들고 표층수온이 상대적으로 기온보다 높아지며 이후 동계까지 지속된다. 동중국해의 하계에서 나타나는 표층수온 변화를 분석하기 위해 8월 표층수온의 이상값을 이용하여 양(04', 06', 07', 13', 16', 17')과 음(03', 05', 08', 09', 10', 11', 12', 14', 15')의 이상값을 가지는 해를 분류하였다. 두 시기의 공통점은 공간적으로 표층수온이 연구해역의 남쪽보다는 북쪽에서, 동쪽보다는 서쪽에서 상대적으로 더 큰 변화를 보이고, 기온과 순열속도 이와 유사한 변화를 나타냈다. 그러나 동중국해의 8월 표층수온 변화에서 양의 이상값을 보이는 시기는 음의 이상값을 보이는 시기보다 표층수온과 기온의 상승률이 상대적으로 높고, 열속의 값도 상대적으로 증가되었다. 전체 연구기간 중에서 하계 표층수온의 변화는 일반적으로 기온과 높은 상관관계를 나타내지만, 표층수온과 기온의 상호관계에서 일반적인 경향과 차이를 나타내는 시기도 있었다(10', 12', 15', 16'). 2010년과 2012년의 8월 표층수온은 기온보다 평균 $0.5^{\circ}C$ 이상 감소되어 나타나는데, 연구해역을 관통한 태풍에 의한 것으로 여겨진다. 2015년의 경우는 표층수온보다 기온의 감소(< $0.5^{\circ}C$)가 상대적으로 크게 나타났으며 이는 동아시아 하계몬순의 약화로 인한 것으로 사료된다. 2016년은 연구기간 동안 표층수온과 기온이 가장 높게 나타났고, 표층수온이 기온보다도 상대적으로 더 높은 온도 상승(> $1^{\circ}C$)을 보였다. 위성과 열속 자료에서 표층수온의 변화는 중국 기원 장강희석수가 이동하는 해역에서 상대적으로 증가되어 나타났고, 이런 원인의 분석을 위해 더 많은 연구가 필요하지만 기온 상승에 의한 효과 이외에도 중국 기원 장강희석수의 확장과 같은 외적 요인에 의해서 수온이 이상 상승된 것으로 사료된다.

• 동의신경정신과학회지
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• 제8권2호
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• pp.39-50
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• 1997

This experiment was to investigate the antioxidant effect of Sesimtang(SST) on brain tissues of mouse. The experimental groups were divided into three groups and treated ad follows for 15 days ; Normal group(NC), Vt.E admistrated group(PC), SST administrated Group(SST). After the extracting microsome from brain of mouse, those were measured the amounts of oxidant materials like MDA(malonaldehyde) and $H_2O_2$, then activities of antioxidant enzymes like SOD(superoxide dismutase), catalase, NADPH-cytochrome P-450 reductase. The results were as follows; 1. In TBA reaction to measure the amount of MDA, oxidant material of brain tissue of aged rat, both treated groups showed significant decrease. 2. Hydrogen peroxide formation was showed significant decrease in both treated groups than normal group. 3. Superoxide dismutase activity was increased in both treated groups than normal group, and showed little change in SST administrated group than normal group. 4. Catalase activity was increased in both treated groups than normal group. 5. NADPH-cytochrome P-450 reductase activity was increased in both treated groups than normal group.