• Title/Summary/Keyword: SS

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Conversion of Coordinated Sulfur Atom into Sulfoxide Group via Oxidation Reaction of Metal Complexes of Tetradentates and Sulfur Amino Acids (네자리 리간드-황아미노산 금속착물의 산화반응에 의한 배위된 황원자의 sulfoxide 원자단으로의 전환)

  • Sung Sil Lee;Peter Fu;Sung Rack Choi;Moo Jin Jun
    • Journal of the Korean Chemical Society
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    • v.33 no.5
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    • pp.516-521
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    • 1989
  • Reaction between the $N_2O_2-type$ tetradentate ligand, ethylenediamine-N,N'-di-S-${\alpha}$-isobutylacetic acid (SS-emiba) and $RhCl_3{\cdot}3H_2O$ has yielded ${\Delta}-s-cis-\;and\;{\wedge}-uns-cis-[Rh(SS-eniba)Cl_2]-$. ${\Delta}-s-cis-[Rh(SS-eniba)Cl_2]^-$ has been utilized to react with S-methyl-L-cystcine(Smc) to give ${\Delta}-s-cis-[Rh(SS-eniba(Smc)]^+$. The oxidation of ${\Delta}-s-cis-[Rh(SS-eniba(Smc)]^+$ using $H_2O_2$ has produced ${\Delta}-s-cis-[Rh(SS-eniba)(Smc-o)]^+$, in which the coordinated sulfur has been converted into the sulfoxide group. In a separate series of experiments the S-methyl-L-cysteine is oxidized by $H_2O_2$ to give S-methyl-L-cysteine sulfoxide, which is then coordinated to ${\Delta}-s-cis-[Rh(SS-eniba)Cl2]^-$ to make the standard complet of ${\Delta}-s-cis-[Rh(SS-eniba)(Sme-o)]+$ for comparison with the complex obtained from the oxidation of ${\Delta}-s-cis-[Rh(SS-eniba)(Smc)]^+\;by\;H_2O_2.$

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Usefulness of SUPAC-SS in Dealing with Postapproval Changes to Semisold Dosage Forms (반고형 제제의 제품허가 후 변경사항을 다루는 SUPAC-SS)

  • Cho, Mi-Hyun;Suk, Kui-Duk;Sah, Hong-Kee
    • Journal of Pharmaceutical Investigation
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    • v.35 no.3
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    • pp.207-224
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    • 2005
  • The objective of this study was to explore the principles of SUPAC-SS and its regulatory application in handling postapproval changes to nonsterile semisolid dosage forms. The types of postapproval changes that SUPAC-SS described were modifications in formulation (components and composition), batch size, manufacturing equipment & process, and the site of manufacturing. SUPAC-SS defined the levels of postapproval changes and what chemistry, manufacturing, and control tests should be conducted for each change level. The guidance also specified several occasions the manufacturers should perform in vitro release test (Franz cell diffusion test) and/or in vivo bioequivalence test. Finally, SUPAC-SS classified appropriate filing forms to be used in supporting postapproval changes. It was crystal clear that SUPAC-SS helped maintain the safety and quality of approved semisolid dosage forms when they were subject to certain postapproval changes. The availability of SUPAC-SS made contributions to reducing regulatory burdens of the industry, as well as expediting the postapproval process of regulatory agencies. This study also shed light on the background of relevant pharmaceutical sciences that the SUPAC-SS guidance adopted. Finally, the KFDA and the industry were strongly urged to implant a similar guidance in handling postapproval changes to semisolid dosage forms available in the Korean marketplace.

Development of Integrated Turbidity model for Deacheong Reservoir and Downstream river. (대청호와 하류하천 통합 탁수 예측 모델 개발)

  • Jung, Yong-Rak;Chung, Se-Woong;Shin, Sang-Il
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.1393-1397
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    • 2008
  • 본 연구의 목적은 대청호와 하류 하천을 연계하여 연속적으로 부유물질의 이송, 확산, 침강과정을 해석 할 수 있는 통합 탁수 모델을 구축하는데 있다. 저수지와 하천을 연속적으로 모의하기 위해서 횡방향 평균 2차원 수리 수질 모델인 CE-QUAL-W2 (W2)를 사용하였다. 그러나 W2모델은 탁도를 모의 할 수 있는 알고리즘이 없기 때문에 모델 경계지점에서의 탁도-부유사(SS) 농도 상관관계를 조사하여 연속 측정된 탁도를 SS로 변환하였고, SS를 입자크기에 따라 3개의 그룹으로 나누어 각각의 침강속도가 다르게 모의하였다. 모의된 SS는 다시 저수지내 관측지점의 탁도-SS 상관관계를 이용해 탁도로 변환하여 실측값과 비교하였고, 하류 하천에서 취수하는 부여 취수장의 탁도-SS 상관관계를 이용하여 취수 원수의 탁도와 모의값을 비교하였다. 하천의 탁도는 실측값이 없는 관계로 모의된 SS를 그대로 하천의 SS 실측값과 비교하였다. 연구결과 통합모델은 저수지내에서 탁도의 수심별 농도를 잘 예측하였고 입자 크기별 침강속도를 고려한 결과 기존의 단일 SS 침강속도 모델에 비해 탁도 예측 성능이 향상되었다. 모델은 강우시 하천에서 급증하는 SS의 농도 변화를 잘 예측하였고, 금강 하류에 위치한 부여 취수장의 일별 취수 원수의 탁도 시계열 변화와도 비교적 잘 일치하였다.

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SS Lac IN OPEN CLUSTER NGC 7209 (산개성단 NGC 7209에 속한 쌍성 SS Lac)

  • 강영운
    • Journal of Astronomy and Space Sciences
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    • v.14 no.2
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    • pp.216-224
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    • 1997
  • We present IUE observations in far ultraviolet region for SS Lac in open cluster NGC 7209. The IUE short wavelength spectrum and long wavelength spectrum were merged to produce an energy distribution curve between $1200{AA}$ and $3200{AA}$. The curve has been unreddened to take out reddening effect. Then the surface temperature, gravity and abundance of SS Lac were determined based on the Kurucz model atmosphere. The photographic light curve produced before cessation of eclipse were analyzed for photometric solutions. We confirmed SS Lac is a member of open cluster NGC 7209 based on its possible distance. The main reason for the cessation of eclipse is the change of the system's orbital inclination rather than collisional merge of two stars.

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Experimental Study on Plane Stress Fracture Toughness and Fatigue Crack Propagation of SS304 and SS316 (SS304와 SS316의 평면응력 파괴인성치 측정과 피로 균열 전파에 대한 실험적 연구)

  • Lee, O.S.;Han, Y.S.;Yoo, S.S.
    • Journal of the Society of Naval Architects of Korea
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    • v.34 no.3
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    • pp.61-69
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    • 1997
  • A simple and relatively new experimental method is proposed to estimate the plane stress fracture toughness by using compact tension (CT) specimen. The anti-buckling plates (fabricated to prevent the buckling caused by the 45 plastic yielding around crack tip under the plane stress condition) help to determine the relatively accurate plane stress fracture toughness of two stainless steels (SS304 and SS316). The fatigue crack propagation behavior of two stainless steels under two different loading conditions such as 10Hz and 5Hz frequency fatigue loadings was investigated by using image analysis technique (IAT) which renders several technical advantages over various conventional measuring methods. It was found that the IAT could be used to estimate fatigue crack lengths more effectively. Furthermore, it was suggested that we might control the measuring time interval for fatigue crack propagation by nearly automatically controlled technical process with the help of IAT.

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Implementation of FM-DS/SS System Using Synchronous Oscillator (동기발진기를 이용한 FM-DS/SS 통신 시스템의 구현)

  • 정명덕;변건식
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.10 no.6
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    • pp.835-846
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    • 1999
  • In this experiment I have made FM-DS/SS system replacing 170.120 MHz by utilizing FM transmitter and receiver. In the transmitter, the result shows that the modulated FM-DS/SS signal is a typical $(sin \chi/\chi)^2$ spectrum by using the clock(1.329 MHz) of PN divided from FM carrier. In the receiver, SO(Synchronous Oscillator) was applied to despread. Like figure 1, 2, and 4 when I applied SO, which consists of sliding correlator, to synchronous a favorable properties could be obtained in the receiver of FM-DS/SS system. In this paper, I used SO in order to take synchronous in the construction of FM-DS/SS system, and to support it I presented the result of the experiment on synchronous curve and properties of OS.

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Narrow Band Interference Rejection for Spectrum Overlay Communications (주파수 복수통신을 위한 협대역 간섭신호제거)

  • 김제우;김희동;조동호
    • Information and Communications Magazine
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    • v.13 no.11
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    • pp.181-191
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    • 1996
  • In this paper we discuss narrow-band interference rejection schemes for spectrum overlay communications where direct sequence spread spectrum (DS/SS) communication system and narrow-band communication systems share the same frequency band. In this case, it is essential to reject the narrow-band signals to guarantee the performance of DS/SS system, while it is not necessarily required to reject the DS/SS signal to recover the narrow-band signal. We discuss several schemes such as time domain processing, frequency domain processing and exploiting the device characteristics to reduce the effect of narrow-band signal on DS/SS communication systems. Furthermore, we suggest a structure of tunable notch filter using gyrator that can easily be customized to ASIC.

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Topographical Change Monitoring of the Sandbar and Estimation of Suspended Solid Flux in the Nakdong River Estuary - Focused on Jinudo - (낙동강 하구역 사주지형 변동과 부유사(SS) 수송량 산정 - 진우도를 중심으로 -)

  • Lee, I.C.;Lim, S.P.;Yoon, H.S.;Kim, H.T.
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.11 no.2
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    • pp.70-77
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    • 2008
  • In this study, to establish countermeasure from marine casualties as a basic study fur long-term prediction of topographical change around Jinudo in the Nakdong river estuary, spatio-temporal topographical change monitoring was carried out. Also, in order to estimate the deposition variations concerning SS (Suspended Solid) flux which moved at St.S1 during neap and spring tide, respectively. From the topographical monitoring, it was found that the annual mean ground level and deposition rate were 141 mm and 0.36 mm/day and all parts except the northern part of Jinudo had the active topographical changes and a tendency to annually deposit. From vertical distribution of SS net fluxes, $SS_{LH}$ (latitudinal SS net flux) during spring tide overall flows average 28 $kg/m^2/hr$ (eastward), and $SS_{LV}$ (longitudinal SS net flux) flows average 11.1 $kg/m^2/hr$ (northward). And, $SS_{LH}$ overall flows average 4.8 $kg/m^2/hr$ (eastward), and $SS_{LV}$ flows average 1.5 $kg/m^2/hr$ (northward) during neap tide similar with spring tide. The depth averaged values of the latitudinal and longitudinal SS net fluxes during spring tide were approximately 6 times higher than those during neap tide. As result of, it was considered that topographical change of southern part of Jinudo was affected by resuspension of bottom sediments due to strong current in bottom layer during flood flow.

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An Experimental Study of Creep Crack Initiation Behavior in 304 and 316 Stainless Steels (304스케인리스강과 316스테인리스강의 크립 균열 발생 거동에 관한 실험적 연구)

  • 최영환;엄윤용
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.13 no.6
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    • pp.1193-1202
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    • 1989
  • 본 논문에서는 발전소의 소재로 많이 쓰이고 있는 304 스테인리스강(앞으로는 304SS로 표기함)과 316스테인리스강(앞으로는 316SS로 표기함)의 크립 균열 발생 거동 을 각각 600.deg. C와 625.deg. C에서 조사한다. 이 온도는 발전소의 반응기(reactor)에 사용 되는 304SS와 316SS이 받는 온도이다. 즉 304SS와 316SS의 크립 균열 발생을 지배 하는 파괴 매개변수가 무엇인지가 크립 파괴 실험을 통하여 조사된다. 실험 결과는 이미 제안되어 있는 크립 균열 발생 모델에서 예측된 결과와 비교된다. 특히 304SS 와 316SS은 고온에서의 연성도가 변형률 속도에 따라 변하는 것으로 알려져 있다. 본 연구에서는 '변형률 속도에 따른 재료의 연성도의 변화에 근거한 균열 발생 모델' 을 제안하고, 그 모델에서 예측된 크립 발생 거동을 실험 결과와 비교한다.

Effects of Securinega suffructicosa(SS) Extract on Osteoclastogenesis and Gene Expression in RANKL-induced RAW Cell (일엽추 추출물이 RANKL 유도 RAW264.7 Cell의 유전자 발현에 미치는 영향)

  • Lee, Hyo-Keun;Hwang, Gwi-Seo
    • Journal of Society of Preventive Korean Medicine
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    • v.14 no.3
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    • pp.13-26
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    • 2010
  • Objectives : This study was performed to evaluate the effect of Securinega suffructicosa Rehder (SS) on osteoclast differentiation and gene expression. Methods : The osteoclastogenesis and gene expression were determined in RANKL-stimulated RAW 264.7. The results were summarized as followes. Results : SS decreased the number of TRAP positive cell in RANKL-stimulated RAW264.7 cell. SS decreased the expression of RANK, TNF${\alpha}$, and IL-6 in RANKL-stimulated RAW264.7 cell. SS decreased the expression of iNOS and COX-2 in RANKL-stimulated RAW264.7 cell. SS decreased the expression of Cathepsin K in RANKL-stimulated RAW264.7 cell. Conclusions : It is concluded that SS might decrease the bone resorption resulted from decrease of osteoclast differentiation and it's related gene expression.