• Title/Summary/Keyword: SRtP

Search Result 64, Processing Time 0.023 seconds

Effect of a Intentional Scapular Abduction on the Sit-and-Reach Test (의도적인 견갑골 외전이 Sit-and-Reach Test에 미치는 영향)

  • Kim, Suhn-Yeop;Chi, Chang-Yean;Kim, Kwang-Soo
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
    • /
    • v.6 no.1
    • /
    • pp.15-26
    • /
    • 2000
  • Purpose : This study was done to examine the actual effect of the scapular position in these flexibility tests. The purpose of this study was to examine the differences between the measurement of SRT(Sit-and-Reach Test) without intentional abduction of the scapular (pre-test) and with intentional abduction of the scapular (post-test). The hypothesis is: 1. There is no differences in the SRT result of the pre-test and the post-test. 2. There is no differences in the HJA(Hip Joint Angle) result of the pre-test and the post-test. 3. There is no differences in the Spine Motion Test(SMT) result of the pre-test and the post-test. Method : The total 60 people (30 men, 30 women) were participated in this study. In the pre-test, the subjects were asked to sit on the examination table and try the SRT motion; and then the HJA, SRT and the SMT numerical values were taken. In the post-test. the subjects were instructed to intentionally bring the scapula outward from the midline; and the HJA, SRT and the SMT numerical values were taken. Result : In the pre-test. the SRT result averaged 34.17cm. and in the post-test. the SRT result averaged 36.68cm. The difference was about 2.81cm which showed a significant mean statistically (p<0.01). The measurement increased by 8.22%. The HJA was $85.9^{\circ}$ in pre-test, and it was $85.5^{\circ}$ in post-test. giving the $0.4^{\circ}$ differences. Therefore, it didn't have a statistical mean (p>0.05). The SMT value was 69.56cm in the pre-test. and it was 69.28cm in the post-test, about 0.28cm decreased. Therefore, it didn't have a statistical mean (p>0.05). SRT values and HJA values were correlated (p<0.01). SMT values and SRT values (p<0.01), and SMT values and HJA values(p<0.05) were each in counter correlation. Conclusion : The result of the SRT without intentional scapular abduction (34.17cm) and with intentional scapular abduction (36.68cm) showed a significant increase about 8.22% (p<0.01). In SRT, the effect of the intentional scapular abduction on SMT showed no significant means, the pretest value being 69.56cm and the post-test value being 69.28cm (p>0.05).

  • PDF

Inhibitory Effects of Amitriptyline, Sertraline and Chlorpromazine on the Thrombin-induced Aggregation of Platelets (Thrombin성 혈소판응집에 대한 Amitriptyline, Sertraline 및 Chlorpromazine의 억제작용)

  • Choi, Sang-Hyun;Lee, Young-Jae;Shin, Kyung-Ho;Chun, Yeon-Sook;Chun, Boe-Gwun
    • The Korean Journal of Pharmacology
    • /
    • v.31 no.3
    • /
    • pp.299-311
    • /
    • 1995
  • Platelets resemble monoaminergic neurons in several respects, i.e. the uptake of 5-HT and its inhibition, the subcellular storage and release of 5-HT, and the metabolism of aromatic amines brought about by monoamine oxidase. And the 5-HT content of rabbit platelets is well known to be about 40 times higher than that of human platelets. Therefore, this study was carried out to investigate the influences of amitriptyline (AMT) and sertraline (SRT) on the aggregation, contents of signaling second messengers, and protein phosphorylations of rabbit platelets in response to thrombin, 0.25 unit/ml, comparing with those of chlorpromazine (CPZ). Thrombin-induced aggregation was inhibited by SRT $(IC50:4.37{\times}10^{-5}\;M)$, CPZ $(IC50:5.76{\times}10^{-5}\;M)$, and AMT $(IC50:1.15{\times}10^{-4}\;M)$, respectively, and the aggregation by A23187 $(1.0\;{\mu}M)$ or PMA (320 nM) was also inhibited by SRT, CPZ, and AMT. AMT, SRT, and CPZ had little affects on basal contents of platelet $TXB_2$ and $PGE_2$, but all of them inhibited the thrombin-induced increase of $TXB_2$. Thrombin did not change the platelet contents of cAMP and cGMP. CPZ, AMT, and SRT produced the slight decrease of basal cAMP content, and their effects were not affected by thrombin-treatment. But SRT and AMT moderately increased the basal cGMP content, and the cGMP content of thrombin-stimulated platelets was gradually increased by the pretreatment with SRT, AMT, and CPZ. Particularly, the SRT-dependent increase of the cGMP content was notable. Platelet $Ins(1,4,5)P_3$ content was rapidly increased up to a plateau within 10 sec after thrombin-stimulation, AMT, SRT, and CPZ increased the basal $Ins(1,4,5)P_3$ content, and the thrombin-dependent increase was enhanced by pretreatment with CPZ and AMT, but was blunted by SRT. Platelet $[Ca^{2+}]_i$, was rapidly increased up to a peak level within 20 sec after thrombin-stimulation. The increase of $[Ca^{2+}]_i$ was sisnificantly inhibited by AMT, SRT, and CPZ. Thrombin- or PMA-induced phosphorylations of platelet $41{\sim}43\;kDa$ and 20 kDa proteins were significantly inhibited by AMT, SRT, and CPZ. These results suggest that the antiplatelet activities of AMT and CPZ may be considerably attributed to the inhibition of protein kinase C activity, and the activity of SRT may be associated with the inhibitory effect on the thrombin-induced increase of $Ins(1,4,5)P_3$ and the increasing effect on the cGMP content of ptatelets. Therefore, it seems to be evident that AMT and SRT may produce their antidepressant activity, at least, partly through the inhibition of protein kinase C activity or the increase of resting $Ins(1,4,5)P_3$, content and in case of SRT, to a lesser extent, via the increase of cGMP in the brain.

  • PDF

Evaluation of Affecting Factors on N and P removal in Biological SND (Simultaneous Nitrification and Denitrification) Process with NADH Sensor (NADH 센서를 이용한 생물학적 동시 탈질.질산화공정에서 질소, 인제거 영향인자 및 거동 평가)

  • Kim, Han-Lae;Lee, Si-Jin
    • Journal of Environmental Health Sciences
    • /
    • v.34 no.5
    • /
    • pp.374-381
    • /
    • 2008
  • In this study, the factors affecting biological N and P removal using SND (simultaneous nitrification and denitrification) process were investigated and evaluated to examine the possibility of treating N and P through SND with NADH by surveying N and P traces in an aeration tank. Variations of $NH_4^+$-N+$NO_3^-$-N concentration were used to estimate the degree of SND in each point (P2, P3, P4, P5) of the aeration tank and these variations showed that denitrification efficiency in P2 (front zone), nitrification and denitrification efficiencies in P4 (middle zone) were 67%, 86% and 39%, respectively. When $PO_4^{-3}$-P concentration was analyzed in each point of the aeration tank, it was shown that $PO_4^{-3}$-P concentration coming into P2 was 1.25 mg/L, which increased to 2.22 mg/L by P release in P2 zone and then decreased to 0.74 mg/L by P uptake in P4. Consequently, we were able to estimate which high P removal efficiency observed in this study was caused by biological phosphorus removal. To determine the operating factors affecting effluent T-N, we analyzed the correlation among FN/M ratio, C/N ratio, Temp., SRT etc and these results showed that the correlation among FN/M ratio, C/N ratio and Temp was not high. However, the relationship of SRT and other parameters (effluent $NH_4^+$-N and effluent BOD) and the short SRT could have an affect on effluent $NH_4^+$-N and so effluent BOD could be increased. Thus, SRT operation should be controlled over 10 days. The results for analyzing the correlation between SRT and influent $NO_3^-$-N in order to investigate the operating factors affecting effluent T-P showed that T-P or $PO_4^{-3}$-P was not highly correlation with SRT, whereas $PO_4^{-3}$-P concentration increased along with increasing $NO_3^-$-N concentration into P2. Based on these results, we concluded, using regression analysis (R2=0.97), that effluent $PO_4^{-3}$-P concentration depends on $NO_3^-$-N concentration into P2.

A Flexibility Assessment of Hamstring Muscle Length in 10year old Children as Affected the Long-sitting Position (1개 초등학교 3학년생의 슬괵근 유연성 평가)

  • Chu Min;Kwon Gy-Joon;Kang Sung-Guk;Kwon Hwal-Ran;Park Dong-Bin;Park Jeon-Jung
    • The Journal of Korean Physical Therapy
    • /
    • v.12 no.1
    • /
    • pp.73-78
    • /
    • 2000
  • The Sit-and-Reach Test (SRT) is commonly nea to assess flexibility of the spine and length of the hamstring muscle, The purpose of this study was to describe hamstring muscle length as reflected by use of the SRT, the Hip Joint Angle (HJA) and Sack length(from C7 to S2) in children, to examine the correlation between Back length, SRT and HJA measurements and to examine gender differences. The 162 subjects were participated without known musculoskeletal and neurological impairments of their spine or lower exeremities. In the Long-silting position, the Back length, SRT and HJA measurements were obtained. A mean Back length value of 46.2cm, a mean SRT value of 29.4cm and a mean HJA of 77,0 degrees were obtained including all subjects. There was a strong correlation between the SRT and HJA measurements (r=.66). There were a difference between boys and girls in Back(p=.0019) and HJA measurements (p=.015). The results of this study suggest that measurements for the SRT and HJA were correlated than Back. The HJA measurements guide treatment more effectively than do Back length and SRT measurements.

  • PDF

The outcome of surfactant replacement therapy in above nearterm neonates with severe pulmonary disease (준 만삭 이상아에서 폐표면 활성제 보충요법의 성적)

  • Shon, Su-Min;Lee, Bo-Young;Kim, Chun-Soo;Lee, Sang-Lak;Kwon, Tae-Chan
    • Clinical and Experimental Pediatrics
    • /
    • v.50 no.12
    • /
    • pp.1200-1205
    • /
    • 2007
  • Purpose : We performed this study to investigate the outcome of surfactant replacement therapy (SRT) in above nearterm neonates who were required mechanical ventilatory care due to meconium aspiration pneumonia (MAP), respiratory distress syndrome (RDS) or other severe pneumonia (PN). Methods : 48 patients, gestational period ${\geq}36weeks$, who were admitted in NICU of Dongsan Medical Center, Keimyung University between July 1999 and June 2004 were enrolled. They were divided into three groups, MAP group (15 cases), RDS group (27 cases) and PN group (6 cases). All patients were received SRT and evaluated several clinical data (gestational age, oxygen index, duration of ventilator care) and outcome (complications and mortality rate) between pre-SRT and post-SRT. The mean dose of surfactant (modified bovine surfactant, Newfacten, Yuhan Co., Seoul, Korea) was 120 mg/kg. Results : Among each groups, mean pre-SRT OI was higher in MAP group ($21{\pm}3.2$) than other groups, mean duration (days) of ventilatory care and oxygen therapy were similar distributions. Compared with pre-SRT values, significant improvements (P<0.05) in mean values for FiO2 and oxygenation index were documented at 12 hours after SRT. Early complications (persistent pulmonary hypertension of newborm, pneumothorax) and survival rate were lower in MAP group. Within RDS group, earlier SRT (given before 12 hours of life) revealed significantly lower early complication rate than later SRT (given after 12 hours of life) (13.3% vs 58.3%, P<0.05) Conclusion : Our study suggested that SRT seems to be an effective therapy in above nearterm neonates with severe pulmonary disease, and earlier SRT tends to reduce complications in RDS group than later therapy.

Effects of mixing/aeration ratio and SRT on nutrient removal in SBR process (연속회분식반응조 공정에서 교반/폭기비와 SRT가 영양염류제거에 미치는 영향)

  • Jeon, Seok-Jun;Kim, Han-Soo
    • Journal of Korean Society on Water Environment
    • /
    • v.18 no.3
    • /
    • pp.291-301
    • /
    • 2002
  • In this study, nutrients treatment by sequencing batch reactors(SBR) was performed. Nitrogen and phosphorus removal efficiencies were evaluated by changing SRT and mixing/aeration ratio. Not only nitrogen but also phosphorus removal patterns were investigated through track studies on 1 cycle. As SRT was fixed and mixing/aeration ratio was changed, maximum nitrogen removal efficiency was 87.6% at mixing/aeration ratio 0.67. Phosphorus removal efficiencies were more than 85.5% except no mixing condition. As mixing/aeration ratio was fixed and SRT was changed, nitrogen removal efficiencies were 70.5~79.8%, which represented slight changes, while phosphorus removal efficiencies were 49.0~97.3%, which represented sharply decreasing tendency at less than 20 day. Both phosphorus release rate k and maximum phosphorus release rate $P_{max}/M$ were are decreased as SRT was decreased, but they were not affected by mixing/aeration ratio. It was found that there is a linear relationship between ortho-phosphate uptake and maximum ortho-phosphate release.

The Recovery of Carbon Source from Municipal Primary Sludge using Pilot Scale Elutriated Acidogenic Fermentation (Pilot scale 세정산발효를 이용한 하수 일차슬러지의 산발효)

  • Kwon, Kooho;Kim, Siwon;Jung, Yongjun;Min, Kyungsok
    • Journal of Wetlands Research
    • /
    • v.15 no.2
    • /
    • pp.165-170
    • /
    • 2013
  • Pilot scale study was carried out to produce Volatile Fatty Acids with primary sludge from municipal wastewater treatment plant. An acid fermenter was operated at pH 9, $35^{\circ}C$, SRT of 3.5-4.25d, using a final effluent as elutriating water(Mode-I) and pH 9, SRT 5d, temperature of $35^{\circ}C$(Mode-II), $55^{\circ}C$(Mode-III), using a primarily treated water as elutriating water. Although solubilization rate was enhanced with the increase of temperature, the VFAs production rate was decreased. The VS reduction was shown approximately 56%, and the sludge volume reduction was 93%. The optimal conditions for solubilization was obtained at pH 9, $35^{\circ}C$ and SRT of 5d.

The Effect of Dual-task Training on a Serial Reaction Time Task for Motor Learning

  • Choi, Jin-Ho;Park, So Hyun
    • The Journal of Korean Physical Therapy
    • /
    • v.24 no.6
    • /
    • pp.405-408
    • /
    • 2012
  • Purpose: We examined the effect of dual-task and single-task training on serial reaction time (SRT) task performance to determine whether SRT is based more on motor or perception in a dual-task. Methods: Forty healthy adults were divided into two groups: the dual-task group (mean age, $21.8{\pm}1.6$ years) and the single-task group (mean age, $21.7{\pm}1.6$ years). SRT task was conducted total 480 trial. The four figures were presented randomly 16 times. A unit was set as 1 block that would repeat 10 times. Thus, there were a total of 160 trials for each of the three color conditions. The dual-task group performed an SRT task while detecting the color of a specific shape. The end of the task, subjects answered the specific shape number; the single-task group only performed the SRT task. The study consisted of three parts: pre-measurement, task performance, and post-measurement. Results: Differences of pre and post reaction time between two group was higher for the dual-task group as compared to the single task group and there was a significant interaction between time and group (p<0.05). Conclusion: Our results indicate that. short term period SRT is not quiet effective under dual-task conditions, individuals need additional cognitive processes to successfully navigate a task This suggests that dual-task training might not be appropriate for motor learning enhancement, at least when the training is over a short period.

A Study on the Substrate Removal Efficiency with Varing SRT in Anaerobic Treatment of High Organic Wastewater (고농도 유기성폐수의 혐기성처리시 SRT변화에 따른 유기물질 제거효율에 관한 연구)

  • Kim Byeong Ho;Kim Dong Min
    • Journal of environmental and Sanitary engineering
    • /
    • v.4 no.1 s.6
    • /
    • pp.43-52
    • /
    • 1989
  • A synthetic wastewater composed of powdered baby food and inorganic nutrients was treated by five 3.6L anaerobic reactors in order to test the relationship between solids retention time (SRT) and media surface ratio, and the removal efficiencies of organic substrate. Of the five reactors, four were semi-continuously fed stirred-tank reactors and one continuously-stirred batch reactor. The influent was 7430mg/L in COD, 7120 mg/L $BOD_L$ and 6350mg/L in $BOD_5$, respectively. Operating temperature was $35{\pm}1^{\circ}C$ and pH in the range 6.9 to 7.2. In this experimental study it was found that a linear relationship existed, within the experiment range, between SRT and media surface ratio, and that SRT and removal efficiency increased with increasing media surface ratio. The substrate removal efficiencies were 82.7 to $88.2\%$ in COD, 82.9 to $88.4\%$ in $BOD_L$ and 83.3 to $88.7\%$ in $BOD_5$, respectively.

  • PDF

An Evaluation Validity of the Silicone Replica Technique at Measurement on Fit of Fixed Dental Prostheses (고정성 보철물의 적합도 측정 시 사용하는 실리콘 복제본 기술의 정확도 평가)

  • Kim, Jae-Hong;Kim, Ki-Baek
    • Journal of dental hygiene science
    • /
    • v.12 no.6
    • /
    • pp.566-571
    • /
    • 2012
  • Marginal and internal fit are very important factor for the clinical long-term success of fixed dental prostheses (FDPs). A variety of methods have been applied to the measuring marginal and internal fit of FDPs. The purpose of this study was to compare the marginal and internal fit of 2 different measuring methods silicone replica technique [SRT] and die cutting technique (DCT). SRT, the space between die and FDPs were filled with light-body silicone, then stabilized by medium-body silicone. DCT, the FDPs were cemented on definitive dies and embedded into epoxy. The silicone replicas and epoxies were sectioned mesio-distal and measured 4 locations (margin, rounded chamfer, axial, occlusal) and using a digital microscope at a magnification $\times$160. For the SRT the mean${\pm}$SDs fit (${\mu}m$) recorded were: margin $88.7{\pm}22.2$, rounded chamfer $90.6{\pm}25.0$, axial wall $61.5{\pm}21.8$, occlusal $134.9{\pm}30.8$. For the DCT the mean${\pm}$SDs fit (${\mu}m$) recorded were: margin $85.3{\pm}18.0$, rounded chamfer $85.4{\pm}24.7$, axial wall $62.0{\pm}21.3$, occlusal $131.7{\pm}30.5$. The mean${\pm}$SDs size (${\mu}m$) of SRT margin was $88.7{\pm}22.2$ and of DCT margin was $85.3{\pm}18.0$. There were no statistically significant difference (p<0.05) of the four parts between SRT and DCT. It is considered an appropriate case to use SRT at fit of FDPs.