• 제목/요약/키워드: SRtP

검색결과 64건 처리시간 0.025초

의도적인 견갑골 외전이 Sit-and-Reach Test에 미치는 영향 (Effect of a Intentional Scapular Abduction on the Sit-and-Reach Test)

  • 김선엽;지창연;김광수
    • 대한정형도수물리치료학회지
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    • 제6권1호
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    • pp.15-26
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    • 2000
  • Purpose : This study was done to examine the actual effect of the scapular position in these flexibility tests. The purpose of this study was to examine the differences between the measurement of SRT(Sit-and-Reach Test) without intentional abduction of the scapular (pre-test) and with intentional abduction of the scapular (post-test). The hypothesis is: 1. There is no differences in the SRT result of the pre-test and the post-test. 2. There is no differences in the HJA(Hip Joint Angle) result of the pre-test and the post-test. 3. There is no differences in the Spine Motion Test(SMT) result of the pre-test and the post-test. Method : The total 60 people (30 men, 30 women) were participated in this study. In the pre-test, the subjects were asked to sit on the examination table and try the SRT motion; and then the HJA, SRT and the SMT numerical values were taken. In the post-test. the subjects were instructed to intentionally bring the scapula outward from the midline; and the HJA, SRT and the SMT numerical values were taken. Result : In the pre-test. the SRT result averaged 34.17cm. and in the post-test. the SRT result averaged 36.68cm. The difference was about 2.81cm which showed a significant mean statistically (p<0.01). The measurement increased by 8.22%. The HJA was $85.9^{\circ}$ in pre-test, and it was $85.5^{\circ}$ in post-test. giving the $0.4^{\circ}$ differences. Therefore, it didn't have a statistical mean (p>0.05). The SMT value was 69.56cm in the pre-test. and it was 69.28cm in the post-test, about 0.28cm decreased. Therefore, it didn't have a statistical mean (p>0.05). SRT values and HJA values were correlated (p<0.01). SMT values and SRT values (p<0.01), and SMT values and HJA values(p<0.05) were each in counter correlation. Conclusion : The result of the SRT without intentional scapular abduction (34.17cm) and with intentional scapular abduction (36.68cm) showed a significant increase about 8.22% (p<0.01). In SRT, the effect of the intentional scapular abduction on SMT showed no significant means, the pretest value being 69.56cm and the post-test value being 69.28cm (p>0.05).

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Thrombin성 혈소판응집에 대한 Amitriptyline, Sertraline 및 Chlorpromazine의 억제작용 (Inhibitory Effects of Amitriptyline, Sertraline and Chlorpromazine on the Thrombin-induced Aggregation of Platelets)

  • 최상현;이영재;신경호;천연숙;전보권
    • 대한약리학회지
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    • 제31권3호
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    • pp.299-311
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    • 1995
  • 혈소판은 혈전기전의 중요요소로, monoamine성 신경전달물질의 대사에 있어서 신경계와 유사점을 가지고 있다. 따라서 항우울약물인 amitriptyline (AMT)과 sertraline (SRT)의 혈소판응집 억제와 이에 의한 세포내 신호전달 물질의 함량변동 및 단백인산화에 대한 영향을 chlorpromazine (CPZ)과 비교연구함으로써, 이들 약물의 혈소판응집 억제작용의 효능을 검정하고, 항 혈소판 및 항우울 작용기전의 일단을 규명하고자 하였다. SRT, CPZ 및 AMT은 thrombin (0.25 unit/ml)에 의한 혈소판응집을 억제하였으며, 각각의 IC50은 $4.37{\times}10^{-5}\;M$, $5.76{\times}10^{-5}\;M$$1.15{\times}10^{-4}\;M$이었다. 이러한 억제효과는 A23187$(1.0\;{\mu}M)$및 PMA(320 nM)에 의한 혈소판응집에 대해서도 유사하게 나타났다. thrombin은 혈소판응집과 아울러 thromboxane $B_2$$prostaglandin\;E_2$ 생성을 유의하게 증가시켰으며, 이러한 arachidonic acid 생성은 CPZ, AMT 및 SRT에 의하여 현저하게 억제되었다. CPZ, AMT 및 SRT은 cAMP 함량을 용량의존적으로 감소시켰으며, SRT, AMT $(1{\times}10^{-4}\;M)$ 및 CPZ $(3{\times}10^{-5}\;M)$은 cGMP 함량을 증가시키는 경향을 보였다. 한편, $Ins(1,4,5)P_3$ 함량은 thrombin 부하 후 10초 이내에 정점에 도달한 후 45초 이후까지 유지된다. CPZ과 AMT은 혈소판의 $Ins(1,4,5)P_3$ 함량을 현저히 증가시키며, thrombin에 의한 증가도 유의하게 증강시킨다. SRT은 혈소판의 $Ins(1,4,5)P_3$을 증가시키나, thrombin 부하 후 증강되지는 않았다. $Ins(1,4,5)P_3$ 증가에 이어서, $[Ca^{2+}]_i$은 thrombin 부하 후 20초에 최고점에 이르며, 이러한$[Ca^{2+}]_i$, 증가는 세 약물에 의하여 현저하게 억제되었다. 혈소판 단백인산화에 대해서, thrombin은 $41{\sim}43\;kDa$ 및 20kDa 단백인산화를 현저하게 증가시켰으며, 이는 AMT, SRT 및 CPZ에 의하여 억제되었다. CPZ, AMT 및 SRT 등의 세 약물은 유의한 항응집효과와 thromboxane생성억제 효과를 나타냈으며, 이들 약물에 의한 protein kinase C 활성억제 및 $Ins(1,4,5)P_3$의 함량증가는 각각 이들약물의 항응집효과 및 항우울성 작용기전과 연관될 수 있음을 시사한다.

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NADH 센서를 이용한 생물학적 동시 탈질.질산화공정에서 질소, 인제거 영향인자 및 거동 평가 (Evaluation of Affecting Factors on N and P removal in Biological SND (Simultaneous Nitrification and Denitrification) Process with NADH Sensor)

  • 김한래;이시진
    • 한국환경보건학회지
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    • 제34권5호
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    • pp.374-381
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    • 2008
  • In this study, the factors affecting biological N and P removal using SND (simultaneous nitrification and denitrification) process were investigated and evaluated to examine the possibility of treating N and P through SND with NADH by surveying N and P traces in an aeration tank. Variations of $NH_4^+$-N+$NO_3^-$-N concentration were used to estimate the degree of SND in each point (P2, P3, P4, P5) of the aeration tank and these variations showed that denitrification efficiency in P2 (front zone), nitrification and denitrification efficiencies in P4 (middle zone) were 67%, 86% and 39%, respectively. When $PO_4^{-3}$-P concentration was analyzed in each point of the aeration tank, it was shown that $PO_4^{-3}$-P concentration coming into P2 was 1.25 mg/L, which increased to 2.22 mg/L by P release in P2 zone and then decreased to 0.74 mg/L by P uptake in P4. Consequently, we were able to estimate which high P removal efficiency observed in this study was caused by biological phosphorus removal. To determine the operating factors affecting effluent T-N, we analyzed the correlation among FN/M ratio, C/N ratio, Temp., SRT etc and these results showed that the correlation among FN/M ratio, C/N ratio and Temp was not high. However, the relationship of SRT and other parameters (effluent $NH_4^+$-N and effluent BOD) and the short SRT could have an affect on effluent $NH_4^+$-N and so effluent BOD could be increased. Thus, SRT operation should be controlled over 10 days. The results for analyzing the correlation between SRT and influent $NO_3^-$-N in order to investigate the operating factors affecting effluent T-P showed that T-P or $PO_4^{-3}$-P was not highly correlation with SRT, whereas $PO_4^{-3}$-P concentration increased along with increasing $NO_3^-$-N concentration into P2. Based on these results, we concluded, using regression analysis (R2=0.97), that effluent $PO_4^{-3}$-P concentration depends on $NO_3^-$-N concentration into P2.

1개 초등학교 3학년생의 슬괵근 유연성 평가 (A Flexibility Assessment of Hamstring Muscle Length in 10year old Children as Affected the Long-sitting Position)

  • 주민;권기준;강성국;권활란;박동빈;박전정
    • The Journal of Korean Physical Therapy
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    • 제12권1호
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    • pp.73-78
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    • 2000
  • The Sit-and-Reach Test (SRT) is commonly nea to assess flexibility of the spine and length of the hamstring muscle, The purpose of this study was to describe hamstring muscle length as reflected by use of the SRT, the Hip Joint Angle (HJA) and Sack length(from C7 to S2) in children, to examine the correlation between Back length, SRT and HJA measurements and to examine gender differences. The 162 subjects were participated without known musculoskeletal and neurological impairments of their spine or lower exeremities. In the Long-silting position, the Back length, SRT and HJA measurements were obtained. A mean Back length value of 46.2cm, a mean SRT value of 29.4cm and a mean HJA of 77,0 degrees were obtained including all subjects. There was a strong correlation between the SRT and HJA measurements (r=.66). There were a difference between boys and girls in Back(p=.0019) and HJA measurements (p=.015). The results of this study suggest that measurements for the SRT and HJA were correlated than Back. The HJA measurements guide treatment more effectively than do Back length and SRT measurements.

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준 만삭 이상아에서 폐표면 활성제 보충요법의 성적 (The outcome of surfactant replacement therapy in above nearterm neonates with severe pulmonary disease)

  • 손수민;이보영;김천수;이상락;권태찬
    • Clinical and Experimental Pediatrics
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    • 제50권12호
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    • pp.1200-1205
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    • 2007
  • 목 적 : SRT는 주로 RDS이 있는 미숙아에서 시행되어 왔다. 저자들은 폐질환을 주소로 인공 환기 요법이 필요했던 재태 주령 36주 이상의 신생아에서 폐표면 활성제를 이용한 보충요법의 투여 성적를 알아보고자 본 연구를 시행하였다. 방 법 : 1999년 7월부터 2004년 6월까지 계명대학교 동산의료원 신생아 집중치료실에 입원한 후 폐질환을 주소로 인공 환기 요법을 받았던 재태 주령 36주 이상의 환아 중 SRT를 시행 받았던 48명의 환아를 대상으로 원인 질환에 따라 MAP군과 RDS군 그리고 PN군으로 나누어서 후향적으로 의무기록을 분석하였다. 모든 대상 환아들에서 SRT를 시행하였으며 폐표면 활성제(Newfacten: 유한양행, Seoul, Korea)는 120 mg을 생리식염수 2-4 mL에 용해하여 평균 120 mg/kg 용량으로 투여하였는데, RDS 군에서는 투여 6시간 후에도 임상적 호전이 미약할 때는 1회 더 투여하였다. 각 군에서 폐표면 활성제 사용 전 후의 임상지표(흡입 산소 농도 및 산소화 지수)와 폐표면 활성제 투여 시점으로부터의 총 인공 환기기 사용 및 산소 투여 기간을 알아보았으며 성적(합병증 및 생존율)를 분석하였다. 결 과 : 총 48례의 환아 중 MAP 군: 15명, RDS 군: 27명, PN 군: 6명 이었다. 폐표면 활성제 투여 전의 산소화 지수는 MAP 군이 $21.8{\pm}3.2$, RDS 군에서 $18.3{\pm}4.5$, PD 군에서 $18.6{\pm}6.0$였고, SRT 후 12시간째의 산소화 지수는 MAP 군이 $8.61{\pm}6.75$, RDS 군에서 $4.98{\pm}0.69$, PD 군에서 $5.8{\pm}1.19$로 통계적으로 유의하게 개선되었다(P<0.05). 총 인공 환기기 사용기간은 MAP 군이 $4.9{\pm}1.2$일, RDS 군이 $5.5{\pm}2.8$일, PN 군이 $7.2{\pm}4.8$일 이었고 산소 투여기간은 MAP 군이$9.4{\pm}1.7$일, RDS 군이 $8.8{\pm}3.5$일, PN 군이 $10.3{\pm}5.6$일 이었다. 기흉, 신생아 폐 고혈압 지속증 등의 합병증 발생은 MAP 군에서 20%, RDS 군에서 25.9%, PD 군에서 50%로 나타났으며, 이중 RDS 군에서 SRT를 처음 시행한 시간에 따른 합병증의 발생 정도는 생후 12시간 전에 시행한 경우의 발생률이 15례 중 2례(13.3%)로 12시간 이후에 시행한 경우의 12례 중 7례(58.3%) 보다 유의하게 낮았다(P<0.05). 생존율은 MAP 군이 86.7%, RDS군과 PN 군이 모두 100%로 모든 군에서 양호한 예후를 보였다. 결 론 : 중증 폐 질환을 주소로 인공 환기 요법이 필요한 임신기간 36주 이상의 준 만삭 이상아에서의 폐표면 활성제 보충요법은 좋은 임상경과를 가지며 특히 RDS인 경우 생후 12시간 내 투여가 합병증을 줄여서 치료성적의 향상에 도움이 될 것으로 사료된다.

연속회분식반응조 공정에서 교반/폭기비와 SRT가 영양염류제거에 미치는 영향 (Effects of mixing/aeration ratio and SRT on nutrient removal in SBR process)

  • 전석준;김한수
    • 한국물환경학회지
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    • 제18권3호
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    • pp.291-301
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    • 2002
  • In this study, nutrients treatment by sequencing batch reactors(SBR) was performed. Nitrogen and phosphorus removal efficiencies were evaluated by changing SRT and mixing/aeration ratio. Not only nitrogen but also phosphorus removal patterns were investigated through track studies on 1 cycle. As SRT was fixed and mixing/aeration ratio was changed, maximum nitrogen removal efficiency was 87.6% at mixing/aeration ratio 0.67. Phosphorus removal efficiencies were more than 85.5% except no mixing condition. As mixing/aeration ratio was fixed and SRT was changed, nitrogen removal efficiencies were 70.5~79.8%, which represented slight changes, while phosphorus removal efficiencies were 49.0~97.3%, which represented sharply decreasing tendency at less than 20 day. Both phosphorus release rate k and maximum phosphorus release rate $P_{max}/M$ were are decreased as SRT was decreased, but they were not affected by mixing/aeration ratio. It was found that there is a linear relationship between ortho-phosphate uptake and maximum ortho-phosphate release.

Pilot scale 세정산발효를 이용한 하수 일차슬러지의 산발효 (The Recovery of Carbon Source from Municipal Primary Sludge using Pilot Scale Elutriated Acidogenic Fermentation)

  • 권구호;김시원;정용준;민경석
    • 한국습지학회지
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    • 제15권2호
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    • pp.165-170
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    • 2013
  • 본 연구에서는 하수일차슬러지의 가용화 및 산발효를 위한 pilot scale 세정산발효공정의 운전 특성을 검토하였다. 하수일 차슬러지의 가용화 및 산발효 특성을 평가하기 위해 SRT, 세정수 및 운전온도를 변화시켜 실험을 수행하였다. 세정산발 효공정의 가용화율은 온도가 높을수록 증가하는 반면, 산생성율은 중온조건($35^{\circ}C$)이 고온조건($55^{\circ}C$)보다 높게 나타났다. VS 감량은 약 56%, 슬러지 부피감량은 약 93%까지 나타났다. 가용화측면에서 세정산발효공정의 최적운전조건은 pH 9, $35^{\circ}C$ 및 SRT 5일이 적합 할 것으로 판단된다.

The Effect of Dual-task Training on a Serial Reaction Time Task for Motor Learning

  • Choi, Jin-Ho;Park, So Hyun
    • The Journal of Korean Physical Therapy
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    • 제24권6호
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    • pp.405-408
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    • 2012
  • Purpose: We examined the effect of dual-task and single-task training on serial reaction time (SRT) task performance to determine whether SRT is based more on motor or perception in a dual-task. Methods: Forty healthy adults were divided into two groups: the dual-task group (mean age, $21.8{\pm}1.6$ years) and the single-task group (mean age, $21.7{\pm}1.6$ years). SRT task was conducted total 480 trial. The four figures were presented randomly 16 times. A unit was set as 1 block that would repeat 10 times. Thus, there were a total of 160 trials for each of the three color conditions. The dual-task group performed an SRT task while detecting the color of a specific shape. The end of the task, subjects answered the specific shape number; the single-task group only performed the SRT task. The study consisted of three parts: pre-measurement, task performance, and post-measurement. Results: Differences of pre and post reaction time between two group was higher for the dual-task group as compared to the single task group and there was a significant interaction between time and group (p<0.05). Conclusion: Our results indicate that. short term period SRT is not quiet effective under dual-task conditions, individuals need additional cognitive processes to successfully navigate a task This suggests that dual-task training might not be appropriate for motor learning enhancement, at least when the training is over a short period.

고농도 유기성폐수의 혐기성처리시 SRT변화에 따른 유기물질 제거효율에 관한 연구 (A Study on the Substrate Removal Efficiency with Varing SRT in Anaerobic Treatment of High Organic Wastewater)

  • 김병호;김동민
    • 환경위생공학
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    • 제4권1호
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    • pp.43-52
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    • 1989
  • A synthetic wastewater composed of powdered baby food and inorganic nutrients was treated by five 3.6L anaerobic reactors in order to test the relationship between solids retention time (SRT) and media surface ratio, and the removal efficiencies of organic substrate. Of the five reactors, four were semi-continuously fed stirred-tank reactors and one continuously-stirred batch reactor. The influent was 7430mg/L in COD, 7120 mg/L $BOD_L$ and 6350mg/L in $BOD_5$, respectively. Operating temperature was $35{\pm}1^{\circ}C$ and pH in the range 6.9 to 7.2. In this experimental study it was found that a linear relationship existed, within the experiment range, between SRT and media surface ratio, and that SRT and removal efficiency increased with increasing media surface ratio. The substrate removal efficiencies were 82.7 to $88.2\%$ in COD, 82.9 to $88.4\%$ in $BOD_L$ and 83.3 to $88.7\%$ in $BOD_5$, respectively.

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고정성 보철물의 적합도 측정 시 사용하는 실리콘 복제본 기술의 정확도 평가 (An Evaluation Validity of the Silicone Replica Technique at Measurement on Fit of Fixed Dental Prostheses)

  • 김재홍;김기백
    • 치위생과학회지
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    • 제12권6호
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    • pp.566-571
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    • 2012
  • 제한된 조건 하에서 수행된 본 연구에서는 다음과 같은 결론을 얻었다. 1. 치형과 고정성 보철물을 근 원심 방향의 단면에 8지점을 선정한 후 서로 다른 두 가지 방식으로 적합도를 측정하여 비교한 결과 8지점 모두에서 유의한 차이를 보이지 않았다(p<0.05). 2. 8지점을 변연부, 경사부, 축벽부, 교합면으로 분류하여 비교한 결과에서도 역시 두 측정 방법 간에 유의한 차이를 보이지 않았다(p<0.05). 이와 같은 결과를 바탕으로 실리콘 복제본 기술을 이용하여 적합도를 측정하는 것이 치형과 고정성 보철물을 직접 절단하여 단면을 측정하는 것만큼 정확하다는 결론을 얻었다. 따라서 고정성 보철물의 적합도 측정 시 비 파괴적인 방법인 실리콘 복제본 기술을 이용한다면 치형과 고정성 보철물 모두 파괴하지 않고 측정이 가능할 것으로 사료된다.