• 한국의류학회지
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• 제45권1호
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• pp.46-55
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• 2021

Seam puckering and the seam strength of conductive threads used to produce smart clothing were analyzed according to stitching methods and fabrics. Samples were prepared in a lock stitch and zigzag stitch on plain woven and jersey knit fabric, using one type of polyester sewing thread and three types of commercial conductive threads that consisted of two types of stainless-steel conductive threads (TST and MST) and one type of silver conductive thread (SSV). Seam pucker percentages, shapes, and seam strength were measured. On plain woven fabric as well as jersey knit fabric, three-ply TST and MST showed a higher SP percentage compared to a polyester sewing thread. Meanwhile, single-ply SSV showed the lowest SP percentage. In addition, the SP percentage of the zigzag stitch decreased along the weft and course directions of the fabric, and decreased significantly as the number of fabric layers increased. Moreover, there was a marked tendency for a higher SP percentage in jersey knit fabric compared to plain woven fabric, and the two-dimensional cross-section waveforms of stitches obtained using three-dimensional data that showed increased irregular waveforms and peaks in the zigzag stitch. There were no correlations between seam strength and tensile strength.

• 한국자기공명학회논문지
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• 제25권2호
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• pp.24-32
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• 2021

Two new sesterterpenes, including a known sesterterpene, were isolated from the marine sponge Haliclona sp. collected in the Gageo island, Korea. One of the new sesterterpenes (1) was an unusual compound possessing a spiroketal moiety and the other (2) represented a four ring-fused skeleton. The planar structure of compound 1 was identical to gombaspiroketals A and B isolated from the marine sponge Clathria gombawuiensis, but the configuration for the two chiral centers was different each other. On the other hand, the skeletal structure of compound 2 was similar to that of phorone A isolated from Phorbas sp. and a compound from C. gombawuiensis, except for one configuration at C-8. However, in comparing the ¹H and ¹³C NMR spectral data, the proton and carbon chemical shifts for the three compounds were almost consistent. The NOESY spectrum revealed that the C-8 configuration of 2 was reversed to that of the two reported compounds. The configuration for compound 2 was supported by quantum mechanical calculation for the carbon chemical shifts and DP4+ probability for the protons and carbons of 2.

• ALGAE
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• 제37권1호
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• pp.33-47
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• 2022

Two new species of Pseudostaurosiropsis are described based on material collected from rivers in southern United States of America, P. californicus sp. nov. and P. elaboratus sp. nov. Both species have specific characters that set them apart from taxa currently ascribed to the genus. Pseudostaurosiropsis californicus sp. nov. has lanceolate valves with subrostrate, broadly rounded apices, an axial area at the same level as the virgae in internal and external views and both are at the same level as striae in external view, the spine tips are dentate and their growth is produced by filamentous extensions, and it has equal-sized apical pore fields on both valve extremes. On the other hand, P. elaboratus sp. nov. has heavily silicified valves, the virgae are slender than the striae in outer view and wider in inner view, it only has a single, externally occluded apical pore field on one valve extreme, and the spines have a solid core. All species within Pseudostaurosiropsis are contrasted with one another and unique features are described for each based on literature and newly collected image data from type material. The genus is reconsidered and two distinguishing features are recognized: rotae externally occluding the areolae and areolae that are funnel-shaped. These features are contrasted with those in other genera and additional published species that should be included in Pseudostaurosiropsis are discussed.

• Biomolecules & Therapeutics
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• 제32권4호
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• pp.492-498
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• 2024

Bioassay and HPLC-UV guided fractionations of the crude extract of marine-derived Streptomyces sp. SNA-077 have led to the isolation of a red pigment, undecylprodigiosin (1). The chemical structure of undecylprodigiosin (1) was revealed by the interpretation of NMR and mass spectroscopic (MS) data. Further, anti-melanogenic effects of undecylprodigiosin (1) were investigated. First, the melanin contents of undecylprodigiosin (1)-treated B16 cells were evaluated. Furthermore, undecylprodigiosin (1) significantly inhibited the key enzymes involved in melanogenesis, including tyrosinase, tyrosinase related protein-1 (TYRP-1), and dopachrome tautomerase (DCT). The mRNA and protein expression levels of Microphthalmia-associated transcriptian factor (MiTF), a critical transcription factor for tyrosinase gene expression, were also suppressed by undecylprodigiosin (1) treatment in B16 analyses. Collectively, our results suggest for the first time that undecylprodigiosin (1), a potent component isolated from an extract of marine Streptomyces sp. SNA-077, critically exerts the anti-melanogenic ability for melanin synthesis.

• 대한화학회지
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• 제39권7호
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• pp.559-563
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• 1995

인도네시아 Manado만의 Sulawesi에서 채집한 KB cancer cell line에 대해 in vitro로 활성을 갖는 해면 Luffariella sp.으로부터 Germacrene alcohol(1), Aaptamine(2) 및 Hexacyclic terpene(3)을 분리하였으며, 1에대한 spectral data는 문헌치와 비교${\cdot}$분석하여 수정하였다. 이들을 $^1H$, $^13C$ NMR, $^1H$ $^13C$(bond) Heteronuclear Multiple Quantum Coherence Spectroscopy(HMQC), $^1H$$^13C$(2 and 3 bond)Heteronuclear Multiple Bond Correlation Spectroscopy(HMBC), Electron Impact Mass Spectroscopy(EI ms), UV 및 IR에 의해 밝혔다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제20권2호
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• pp.73-81
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• 2020

Background: The international organization for standardization (ISO) 80601-2-61 dictates that the accuracy of a pulse oximeter should be assessed by a controlled desaturation study. We aimed to characterize the relationship between the fraction of inspired oxygen (FiO₂) and peripheral oxygen saturation (SpO₂) using a turnover model by retrospectively analyzing the data obtained from previous controlled desaturation studies. Materials and Methods: Each volunteer was placed in a semi-Fowler's position and connected to a breathing circuit to administer the hypoxic gas mixture containing medical air, oxygen, nitrogen, and carbon dioxide. Volunteers were exposed to various levels of induced hypoxia over 70-100% arterial oxygen saturation (SaO₂). The study period consisted of two rounds of hypoxia and the volunteers were maintained in room air between each round. FiO₂ and SpO₂ were recorded continuously during the study period. A population pharmacodynamic analysis was performed with the NONMEM VII level 4 (ICON Development Solutions, Ellicott City, MD, USA). Results: In total, 2899 SpO₂ data points obtained from 20 volunteers were used to determine the pharmacodynamic characteristics. The pharmacodynamic parameters were as follows: k_out = 0.942 1/min, Imax = 0.802, IC₅₀ = 85.3%, γ = 27.3. Conclusion: The changes in SpO₂ due to decreases in FiO₂ well explained by the turnover model with inhibitory function as a sigmoidal model.

• 한국지능시스템학회논문지
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• 제19권3호
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• pp.297-303
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• 2009

본 논문에서는 비선형 변환에 의해 입력신호를 고차원의 확장공간으로 변환한 후, 주성분분석기법(PCA)에 의해 신호의 특징을 추출하는 기법을 제안한다. 특징추출을 위해 사용되는 기존의 주성분분석기법은 입력데이터가 비선형 특성을 갖는 경우 최적의 변환행렬을 구할 수 없다는 문제점을 가지고 있다. 이러한 문제점을 해결하기 위해, 확장공간상에서 구간별로 입력데이터를 분할한 후 주성분분석기법에 의해 구간별 특징을 추출하는 서브패턴기반 주성분분석기법(SpPCA)을 적용하였다. 다음 단계인 분류단계에서는 MLP 비선형분류기를 이용하여 구간마다 추출된 특징벡터를 이용하여 기준패턴과의 유사도를 산출한다. 최종 분류단계에서는 MLP에 의해서 산출된 유사도에 기반을 둔 융합법칙에 의하여 생체 스펙트럼 패턴을 분류한다. 제안된 방법의 유용성을 보이기 위한 실험결과에서 기존의 방법들에 비해서 향상된 인식결과를 보임을 확인하였다.

• Journal of Ginseng Research
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• 제45권2호
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• pp.305-315
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• 2021

Background: Panax stipuleanatus represents a folk medicine for treatment of inflammation. However, lack of experimental data does not confirm its function. This article aims to investigate the analgesic and anti-inflammatory activities of triterpenoid saponins isolated from P. stipuleanatus. Methods: The chemical characterization of P. stipuleanatus allowed the identification and quantitation of two major compounds. Analgesic effects of triterpenoid saponins were evaluated in two models of thermal- and chemical-stimulated acute pain. Anti-inflammatory effects of triterpenoid saponins were also evaluated using four models of acetic acid-induced vascular permeability, xylene-induced ear edema, carrageenan-induced paw edema, and cotton pellet-induced granuloma in mice. Results: Two triterpenoid saponins of stipuleanosides R₁ (SP-R₁) and R₂ (SP-R₂) were isolated and identified from P. stipuleanatus. The results showed that SP-R₁ and SP-R₂ significantly increased the latency time to thermal pain in the hot plate test and reduced the writhing response in the acetic acid-induced writhing test. SP-R₁ and SP-R₂ caused a significant decrease in vascular permeability, ear edema, paw edema, and granuloma formation in inflammatory models. Further studies showed that the levels of inflammatory mediators, nitric oxide, malondialdehyde, tumor necrosis factor-α, and interleukin 6 in paw tissues were downregulated by SP-R₁ and SP-R₂. In addition, the rational harvest of three- to five-year-old P. stipuleanatus was preferable to obtain a higher level of triterpenoid saponins. SP-R₂ showed the highest content in P. stipuleanatus, which had potential as a chemical marker for quality control of P. stipuleanatus. Conclusion: This study provides important basic information about utilization of P. stipuleanatus resources for production of active triterpenoid saponins.

• Journal of the Korean Data and Information Science Society
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• 제19권3호
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• pp.811-818
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• 2008

This paper is the generalization of the modified two-level skip-lot sampling plan(MTSkSP2) to n-level. The general formulas of the operating characteristic(OC) function, average sample number(ASN) and average outgoing quality(AOQ) for the plan are derived using Markov chain properties.

• 한국ITS학회:학술대회논문집
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• 한국ITS학회 2004년도 제3회 정기총회 및 추계학술대회
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• pp.300-305
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• 2004