• Journal of Korean Neurosurgical Society
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• v.30 no.1
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• pp.41-46
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• 2001

Objective : The exact position of the lesion during the pallidotomy is critical to obtain the clinical improvement of parkinson's disease without damage to surrounding structure. Ventriculogrphy, CT(computed tomograpy) or MRI(magnetic resonance imaging) have been used to determine the initial coordinates of stereotactic target for pallidotomy. The goal of this study was to determine whether microelectrode recording significantly improves the neurophysiologic localization of the target obtained from MRI. Methods : Twenty patients were studied. They underwent a unilateral pallidotomy. Leksell frame was applied and T1 axial images parallel to the AC-PC(anterior commissure-posterior commissure) plane using a 1.5 Tesla MRI with 3mm slice thickness were obtained. Anteroposterior coordinate of target was chosen at 2mm in front of the midcommissural point and lateral coordinate between 19 and 22mm from the midline. The vertical coordinate was calculated on coronal slice using a fast spin echo inversion recovery sequence(FSEIR) related to the position of the choroidal fissure and ranged over 4-5mm below the AC-PC plane. Confirmation of the anatomical target was done on axial slices using the same FSEIR sequence . Microrecording was done at the pallidum contralateral to the symptomatic side using an electrode with a tip diameter of $1{{\mu}m}$ diameter tip and 1.1-1.4 mOhm impedance at 1000Hz. Electrophysiologic localization of the target was also confirmed intraoperatively by macrostimulation. Results : Microrecording techniques were reliable to define the transition from the base of the pallidum which was characterized by the disappearance of spike activity and by the change of the audible background activity. Signals from high amplitude neurons firing at 200-400Hz were recorded in the pallidal base. X, Y and Z coordinates of target obtained from the MRI were within 1mm from the X, Y, Z coordinates obtained with microrecording in 16 patients (80%), 15 patients(75%), 10 patients(50%) respectively. The difference of Y coordinate between on MRI and on microrecording was 4mm in only one patient. Conclusion : The MRI was accurate to localize the target within 1mm of the error from microrecording target in 70% of the patients. 4mm discrepancy was observed only once. We conclude that MRI alone can be used to determine the target for pallidotomy in most patients. However, microrecording technique can still be extremely valuable in patents with aberrant anatomy or unusual MRI coordinates. We also consider physiologic confirmation of the target using macrostimulation to be mandatory in all cases.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.843-850
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• 2020

The purpose of this study is to evaluate the structural risk and weakness of a railway tank car through nonlinear collision analysis according to overseas collision safety standards. The goal is to propose a crash safety design guideline for railway tank cars for transporting dangerous goods in Korea. We analyzed the buffer impact test procedure of railway freight cars prescribed in EN 12663-2 and the tank puncture test criteria prescribed in 49CFR179. A nonlinear finite element model according to each standard was modeled using LS-DYNA, a commercial finite element analysis solver. As a result of the buffing impact test simulation, it was predicted that plastic deformation would not occur at a collision speed of 6 km/h or less. However, plastic deformation was detected at the rear of the center sill and at the tank center supporting the structure at a collision speed of 8 km/h or more. As a result of a head-on test simulation of tank puncture, the outer tank shell was destroyed at the corner of the tank head when 4% of the kinetic energy of the impacter was absorbed. The tank shell was destroyed in the area of contact with the impacter in the test mode analysis of tank shell puncture when the kinetic energy of the moving vehicle was reduced by 30%. Therefore, the simulation results of the puncture test show that fracture at the tank shell and leakage of the internal material is expected. Consequently, protection and structural design reinforcement are required on railway tank cars in Korea.

• Journal of environmental and Sanitary engineering
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• v.18 no.3 s.49
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• pp.27-34
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• 2003

An objective of local exhaust hood design is to design the hood to operate as efficiently as possible. The greatest loss normally occurs at the entrance to the duct, due to the vena contracta in the throat of the duct. This can be accomplished by minimizing the loss that results from the vena contracta. There have been little studied to be cost-effective approach as installing simple instrument inside the throat of the hood. The aims of this paper were to minimize entry loss using inner square, and to measure the effect of inner square when installed inside hood throat. The results of this study were as follows; First, the magnitude of vena contracta could be considered as the difference between direct measured velocity and calculated velocity, which is from Bernoulli theory. In circle hood, calculated velocity and direct measured velocity were 10.7m/sec and 10.3n/sec, respectively. And the calculated velocity and direct measured velocity in square hood were 7.7m./sec and 6.5m/sec, respectively. Second, effect of inner square by width was carried out. The widths of inner square were L/1(18cm), L/2(9cm), L/3(6cm) and L/6(3cm). In case inner square was installed with 3cm width, the entry of coefficient was 0.93, comparing with 0.85 of entry of coefficient of general hood. Third, effect of inner square by distance from hood inside surface to inner square was carried out. The distances were L/3(6cm), L/6(3cm), L/9(2cm) and L/l8(1cm). In case the distance was 3cm the best efficiency was shown (Ce= 0.93). Fourth, effect of inner square by location from hood entry to duct inside was carried out. The locations of inner square were entry(0cm), L/6(3cm), L/3(6cm), L/2(9cm) and L/l(12cm). In case the location was 0cm, 3cm and 6cm the entry of coefficients were 0.93, 0.92 and 0.90, respectively.

• Journal of Conservation Science
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• v.23
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• pp.1-10
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• 2008

Consolidants based on tetraethoxysilane (TEOS) such as alkoxysilanes have been widely used for the consolidation of decaying stone heritages. Low-viscosity alkoxysilanes penetrate inside the decaying stone and polymerize within the porous structure of the decaying stone, significantly increasing the cohesion of the material. However, TEOS-based consolidants suffer from practical drawbacks, such as crack formation of the gel during the drying phase due to the developed capillary force, which is typical for TEOS-based consolidants. We prepared new consolidants TEOS-based consolidants containing flexible (3-glycidoxypropyl)trimethoxysilane (GPTMS) and silica nanoparticles (or polyhedral oligomeric silsesquioxanes (POSS)) in order to reduce capillary force development during gel drying. Since the consolidants should have a good interaction with the component of the stone in order to connect the isolate grains of decaying stone, the adhesion interaction of the developed consolidants on the surface of the granite was macroscopically investigated by the ISO 2409 cross cutting test. The adhesion interaction decreased with the addition of silica nanoparticle and POSS while it increased with the addition of GPTMS in TEOS solution.

• YAKHAK HOEJI
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• v.40 no.4
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• pp.428-437
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• 1996

The in vitro and in vivo antibacterial activities of a new fluoroquinolone, DWP20364(1-cyclopropyl-5-amino-6,8-difluoro-7-(2,7-diazabicyclo[3.3.0]oto-4-ene-7-yl)-1 ,4-di-hydro-4-oxoquinoline-3-carboxylic acid) were evaluated in comparison with those of ciprofloxacin(CPFX), sparfloxacin(SPFX) and ofloxacin(OFLX). DWP20364 was more potent than CPFX and OFLX against Staphylococcus spp., Streptococcus spp. and Enterococcus faecium MD8b and it was similarly or slightly less active than CPFX against Escherichia spp. and Pseudomonas spp.. For MRSA and OFLX resistant strains (Staphylococcus spp.(14),Enterococcus spp.(4), Acinetobacter spp.(2), Pseudomonas spp.(9), Klebsiella spp.(2) and Serratia spp.(6)),DWP20364(MICs for 90% of strains,0.025 and 12.5${\mu}$g/ml, respectively) was 4 to 32 folds more potent than SPFX and CPFX. The activity of DWP20364 decreased moderately in the presence of 5mM $Mg^{2+}$. However, various pHs and the concentrations of various serum had no effect on the activity of DWP20364. DWP20364 possessed a bacteriocidal effect at the 1MIC against gram positive and gram negative strains. The protective effect of DWP20364 against systemic infections in mice caused by S. aureus Smith or S. aureus L2379 was superior to that of CPFX and SPFX but it was less active than that of CPFX against infection by P. aeruginosa E-2.

• Journal of the Korean Wood Science and Technology
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• v.39 no.2
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• pp.140-147
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• 2011

The strength properties of wooden retaining wall which was made with pitch pine were evaluated. Wooden retaining wall was made with diameter 90 mm of pitch pine round posts treated with CUAZ-2 (Copper Azole). The length of the front stretcher of the retaining wall was 3,000 mm. The distance between the headers (the notched member) is 1,000 mm in center and is 900 mm in side. There were connections every 2,000 mm because actually the length of stretcher is limited in the retaining wall. The strength test was carried out according to connection type because the section between stretchers can act as a defect. A result of the strength test according to connection type confirms that connection does not act as defect because the strength of retaining wall in single stretcher is similar to that in the section between stretchers. The strength test of the wooden retaining wall was carried out in 5 types according to the condition of the base section. When the upper soil pressure was 9.8 kN/$m^2$, the maximum load of the retaining wall fixing the front foundation shows higher values than those of others. But the total deformation is lower in the retaining wall not to fix a base section than in that to fix a base section. It is thought that the retaining wall not to fix a base section shows low value because the deformation is distributed throughout the retaining wall and it is confirmed that the soil pressure affects supporting the structure because the deformation of the retaining wall under low pressure is 3~4 fold higher than those of others. The failure mode of the retaining wall is the overturning type because the high section is deformed. Mostly, the failure mode is the separation of the header in the notched section.

• Journal of the Korean Vacuum Society
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• v.21 no.1
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• pp.62-68
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• 2012

The conversion efficiency of solar cells depending on incident angle of light is important for building-integrated photovoltaics (BIPV) applications. The quantum efficiency is the ratio of the number of charge carriers collected by the solar cell to the number of photons of a given energy shining on the solar cell. The analysis of angle dependence of quantum efficiencies give more information upon the variation of power output of a solar cell by the incident angle of light. The variations in power output of solar cells with increasing angle of incidence is different for the type of cell structures. In this study we present the results of the quantum efficiency measurement of single-crystalline silicon solar cells and a-Si:H thin-film solar cells with the angle of incidence of light. As a result, as the angle of incidence increases in single-crystalline silicon solar cells, quantum efficiency at all wavelength (300~1,100 nm) of light were reduced. But in case of a-Si:H thin-film solar cells, quantum efficiency was increased or maintained at the angle of incidence from 0 degree to about 40 degrees and dramatically decrease at more than 40 degrees in the range of visible light. This results of quantum efficiency with increasing incident angle were caused by haze and interference effects in thin-film structure. Thus, the structural optimization considering incident angle dependence of solar cells is expected to benefit BIPV.

• Korean Journal of Optics and Photonics
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• v.19 no.2
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• pp.127-131
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• 2008

A refractometric glucose biosensor incorporating a vertically coupled microring resonator in polymers was proposed and realized. The ring was covered with a target analyte of glucose solution with a certain concentration, so that its effective refractive index could be altered and, as a result, the resonance wavelength of the sensor was shifted. Therefore the concentration of the glucose solution can be estimated by observing the shift in the resonance wavelength. Two schemes were exploited for enhancing the sensitivity of the sensor. First, the effective refractive index of the polymeric waveguide used for the resonator sensor was adjusted to approach that of the target analyte as best as possible. Second, the ring waveguide, which serves as a crucial sensing part, was appropriately over-etched to enlarge its contact area with the analyte. The proposed resonator sensor was designed with the beam propagation method. The refractive indices of the core and cladding polymer involved were 1.430 and 1.375 respectively, leading to the waveguide's effective refractive index of ${\sim}1.390$, which is faiirly close to that of the glucose solution of ${\sim}1.333$. The prepared ring resonator with the $400-{\mu}m$ radius exhibited the free spectral range of 0.66 nm, the bandwidth of 0.15 nm, and the quality factor of 10,000. For the sensor operating at 1,550 nm wavelength, the achieved sensitivity was as great as 0.28 pm/(mg/dL), which is equivalent to 200 nm/RIU.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.43 no.1 s.343
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• pp.17-26
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• 2006

The analog Viterbi decoder for the PR (1 2 2 1) which is used for BVD read channel is designed with circular analog parallel circuits. Since the inter symbol interference is serious problem in the high density magnetic storage device or DVD, the PRML technology is normally employed for the purpose of minimizing the decoding error. The feature of the PRML technology is with the multi-level coding according to the predetermined combining rule among the neighboring symbols and with the decoding according to the known combining rule. Though the conventional PRML technology is implemented with the digital circuits, the recent trend towards this end is with the utilization of the analog circuits due to the requirements of higher speed and lower power in the DVD read channel. In this study, the Viterbi decoder which is the bottleneck of the PRML implementation is designed with the analog parallel circuit structure. The designed Viterbi decoder for the PR (1 2 2 1) signal shows 3 times faster in the speed and 1/3 times less in the power consumption than thoseoftheconventionaldigitalcounterpart.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.30 no.4
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• pp.271-281
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• 2004

Adenoid cystic carcinoma is malignant tumor in salivary gland, and its behavior is very invasive. Of all malignant tumor adenoid cystic carcinoma is occured in frequency of 4.4% in major salivary gland, and 1.29% in minor salivary gland. Histopathologically, adenoid cystic carcinoma is characterized by a cribriform appearance, and tubular form and solid nest type tumor can be seen. The tumor cell structure composed of modified myoepithelial cell, and basaloid cell. Extracellular matrix of this tumor cell contains variable ground substance with basement membrane component. Basement membrane matrix composed of collagen fibers, glycoproteins, proteoglycans, and its function is well known that it participate in differentiation, proliferation, and growth of tumor cell. Basement membrane molecule is essential for invasion of peripheral nerve, blood vessel, skeletal muscle in tumor cell of adenoid cystic carcinoma. In many studies, the tumor cell of adenoid cystic carcinoma containing modified myoepithelial cell participate in synthesis of proteoglycan. In this study, tissue sample of adenoid cystic carcinoma of human salivary gland were obtained from 15 surgical specimen, and all specimen were routinely fixed in 10% formalin and embedded. Serial $4-{\mu}m$ thick sections were cut from paraffin blocks. the histopathologic evaluation was done with light microscopy. And, the immunohistochemical staining, characteristics of glycosaminoglycan were observed. For biochemical analysis of glycosaminoglycan, isolation of crude glycosaminoglycan from tumor tissue and Western bolt analysis were carried out. With transmission electomicroscopy, tumor cell were observed. Biologic behavior of adenoid cystic carcinoma was observed with distribution and expression of basement membrane of glycosaminoglycan in tumor cells, The results obtained were as follows: 1. In immunohistochemical study, chondroitin sulfate is postively stained in tumor cell and interstitial space, dermatan sulfate is weakly stained in ductal cell. But keratan sulfate is negatively stained. 2. In immunohistochemical study, heparan sulfate is strong positive stained in tumor cell and basement membrane, especially in invasion area to peripheral nerve tissue. 3. In transmission electromicroscpic view, the tumor cells are composed modifed myoepithelial cells, and contains many microvilli and rough endoplasmic reticulum. 4. In Western blot analysis, the expression of glycosaminoglycan is expressed mostly in heparan sulfate. From the results obtained in this study, tumor cell of adenoid cystic carcinoma is composed modified myoepithelial cell, and glycosaminoglycan of basement membrane molecule of heparan sulfate and chondroitin sulfate mostly participate in the development and invasiveness of adenoid cystic carcinoma by immunohistochemical study and western blot analysis.