• Asian-Australasian Journal of Animal Sciences
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• 제31권8호
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• pp.1088-1097
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• 2018

Objective: It is commonly accepted that adiponectin binds to its two receptors to regulate fatty acid metabolism in adipocytes. To better understand their functions in the regulation of intramuscular adipogenesis in goats, we cloned the three genes (adiponectin [AdipoQ], adiponectin receptor 1 [AdipoR1], and AdipoR2) encoding these proteins and detected their mRNA distribution in different tissues. We also determined the role of AdipoQ in the adipogenic differentiation of goat skeletal muscle satellite cells (SMSCs). Methods: SMSCs were isolated using 1 mg/mL Pronase E from the longissimus dorsi muscles of 3-day-old female Nanjiang brown goats. Adipogenic differentiation was induced in satellite cells by transferring the cells to Dulbecco's modified Eagle's medium supplemented with an isobutylmethylxanthine, dexamethasone and insulin cocktail. The pEGFP-N1-AD plasmid was transfected into SMSCs using Lipofectamine 2000. Expression of adiponectin in tissues and SMSCs was detected by quantitative polymerase chain reaction and immunocytochemical staining. Results: The three genes were predominantly expressed in adipose and skeletal muscle tissues. According to fluorescence and immunocytochemical analyses, adiponectin protein expression was only observed in the cytoplasm, suggesting that adiponectin is localized to the cytoplasm of goat SMSCs. In SMSCs overexpressing the AdipoQ gene, adiponectin promoted SMSC differentiation into adipocytes and significantly (p<0.05) up-regulated expression of AdipoR2, acetyl-CoA carboxylase, fatty-acid synthase, and sterol regulatory element-binding protein-1, though expression of CCAAT/enhancer-binding $protein-{\alpha}$, peroxisome proliferator-activated receptor ${\gamma}$, and AdipoR1 did not change significantly. Conclusion: Adiponectin induced SMSC differentiation into adipocytes, indicating that adiponectin may promote intramuscular adipogenesis in goat SMSC.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2000년도 가을 학술발표논문집 Vol.27 No.2 (3)
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• pp.129-131
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• 2000

최근 무선 인터넷 서비스에 대한 관심이 고조되면서 관련 기술 개발이 활발히 진행되고 있다. 현재 가장 유력한 국제표준 중 하나로 인식되어 가고 있는 WAP(Wireless Application Protocol)의 규격에 따르면 이동 단말과 WAP 서버는 WAP Gateway를 통하여 통신하도록 되어 있다. 본 논문은 리눅스 기반으로 WAP Gateway와 Server가 통합적으로 지원되는 IWAP 플랫폼의 설계 및 구현에 것이다. 제안된 IWAP 플랫폼은 WAP Gateway JABA 기반의 Server 개발환경, WML Tool-Kit 및 MUI(Management User Interface)등 크게 4개의 모듈로 구성되고, 베어러(bearer) 망으로 SMSC(Short Message Service Center)나 CSD(Circuit Switched Data) 라우터를 고려하였다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 추계학술대회 논문집
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• pp.1627-1633
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• 2004

Safety and punctuality in the subway are considered as critical factors. This system is composed of many factors like signals, rails, electrical power sources, rolling stocks. The effective inspection should be carried out at all the times for the safety and punctuality. Purpose of the rolling stocks maintenance is to offer the optimum condition of vehicles, and minimize the maintenance expenses. This paper suggests appropriate maintenance period of rolling stocks to enhance the utility efficiency in SMSC.

• 대한수학교육학회지:학교수학
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• 제4권3호
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• pp.463-481
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• 2002

In this paper, I review the historical background of "the principle of the permanence of equivalent forms" and sum- marize properties of "the principle of the permanence of equivalent forms" as a kind of heuristic. 1 think that "the principle of the permanence of equivalent forms" can be used effectively for student's discovery of the algebraic structure. There are three ways of using "the principle of the permanence of equivalent forms" in extending number system - an extension on the base of set theory(SMSC), the formal or axiomatic extrapolation and the inductive-extrapolatory method. All those three methods are mixed up and being used potentially at various levels in current Korean text books. "The principle of the permanence of equivalent forms" is used most effectively in the subject of the exponent. 1 try to present a situation that makes the students find more general definition and cultivate their desirable attitudes for the mathematics in the process of extending the exponent through summarizing the debate between Goel & Robillard(1997) and Tirosh S, Even(1997).

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2011년도 춘계학술논문집 1부
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• pp.53-56
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• 2011

지난 7.7 DDoS(Distributed Denial of Service), 3.3 DDoS 대란을 통해서 보여주듯 DDoS 공격이 네트워크 주요 위협요소로 매우 부각되고 있으나, 공격에 대해서 실시간으로 감지하고 대응하기에 어렵다. 그리고 현재 여러 분야에서 매우 많은 용도로 사용되는 SMS(Short Message Service)도 DDoS 공격 수단으로 사용되어 이동전화 시스템에 큰 혼란을 야기할 수 있다. 기존의 Bloom Filter 탐지 기법은 구조가 간단하고 실시간 탐지가 가능한 장점을 갖지만 오탐지율에 대한 문제점을 가진다. 본 논문에서는 목적지 기반의 다중의 해시함수를 사용한 Counting Bloom Filter 기법을 이용하여 임계치 이상 카운트된 동일한 목적지로 발송되는 SMS에 대하여 공격으로 탐지하고 SMSC에 통보하여 차단시키는 시스템을 제안한다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 추계학술대회 논문집
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• pp.976-981
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• 2005

The Seoul subway line No.2 is the one of the busiest metro service line of the passenger transportation in Seoul metropolitan city. The number of the passengers served by the Seoul subway line No.2 is more than 1.9 million in a day according to the transportation reference of 2004, which is about $15\%$ of the whole population in Seoul metropolitan city. This is the reason why the Seoul Metropolitan Subway Corporation(SMSC) is implementing the refurbishment of the current ATS signalling system of Seoul Line No.2 into the most advanced ATO system with the continuous air-gap telegram transmission through the track circuit without any suspension of the train service either in when or in where, which is the first in the world in its attempt to refurbish the old signalling system under service without any suspension of the train operation.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제38권6호
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• pp.343-353
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• 2012

Objectives: This aim of this study was to effectively isolate mesenchymal stem cells (hSMSCs) from human submandibular skin tissues (termed hSMSCs) and evaluate their characteristics. These hSMSCs were then chemically induced to the neuronal lineage and analyzed for their neurogenic characteristics in vitro. Materials and Methods: Submandibular skin tissues were harvested from four adult patients and cultured in stem cell media. Isolated hSMSCs were evaluated for their multipotency and other stem cell characteristics. These cells were differentiated into neuronal cells with a chemical induction protocol. During the neuronal induction of hSMSCs, morphological changes and the expression of neuron-specific proteins (by fluorescence-activated cell sorting [FACS]) were evaluated. Results: The hSMSCs showed plate-adherence, fibroblast-like growth, expression of the stem-cell transcription factors Oct 4 and Nanog, and positive staining for mesenchymal stem cell (MSC) marker proteins (CD29, CD44, CD90, CD105, and vimentin) and a neural precursor marker (nestin). Moreover, the hSMSCs in this study were successfully differentiated into multiple mesenchymal lineages, including osteocytes, adipocytes, and chondrocytes. Neuron-like cell morphology and various neural markers were highly visible six hours after the neuronal induction of hSMSCs, but their neuron-like characteristics disappeared over time (24-48 hrs). Interestingly, when the chemical induction medium was changed to Dulbecco's Modified Eagle Medium (DMEM) supplemented with fetal bovine serum (FBS), the differentiated cells returned to their hSMSC morphology, and their cell number increased. These results indicate that chemically induced neuron-like cells should not be considered true nerve cells. Conclusion: Isolated hSMSCs have MSC characteristics and express a neural precursor marker, suggesting that human skin is a source of stem cells. However, the in vitro chemical neuronal induction of hSMSC does not produce long-lasting nerve cells and more studies are required before their use in nerve-tissue transplants.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제39권4호
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• pp.150-155
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• 2013

Objectives: The objective of this study is to determine the adequate concentration and to evaluate the osteogenic potential of simvastatin in human maxillary sinus membrane-derived stem cells (hSMSC). Materials and Methods: Mesenchymal stem cells derived from the human maxillary sinus membrane were treated with various concentrations of simvastatin. The adequate concentration of simvastatin for osteogenic induction was determined using bone morphogenetic protein (BMP-2). The efficacy of osteogenic differentiation of simavastatin was verified using osteocalcin mRNA, and the mineralization efficacy of hSMSCs and simvastatin treatment was compared with alkaline phosphatase and von Kossa staining. Results: Expression of BMP-2 mRNA and protein was observed after three days and was dependent on the concentration of simvastatin. Expression of osteocalcin mRNA was observed after three days in the $1.0{\mu}M$ simvastatin-treated group. Mineralization was observed after three days in the simvastatin-treated group. Conclusion: These results suggest that simvastatin induces the osteogenic potential of mesenchymal stem cells derived from the human maxillary sinus membrane mucosa.

• Journal of information and communication convergence engineering
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• 제2권4호
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• pp.219-223
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• 2004

MMS has been seen as the key application in its entry into the 3G mobile markets. Furthermore, the combination of WLAN and 3G wireless technologies will make MMS service more popular, bringing benefits to both service providers and their customers. To realize seamless MMS service over WLAN and CDMA2000 networks, we design and implement new platform architecture by reusing the existing standards and network elements at the same time. We employ loose coupling approach and Mobile IP approach to propose new platform architecture, interfacing MMSC with many existing components. Based on our platform architecture, we also present seamless MMS delivery implementations that can't be possible within the current MMS reference architecture. This paper will make a contribution for service providers to offer their customers with seamless MMS service over WLAN and CDMA2000 networks.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 추계학술대회 논문집
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• pp.897-901
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• 2005

21 century as the knowledge information anger society now our society industry of all fields the rolling stock maintenance conservative standardization enterprise where information anger is being turning out construction Ministry of Transportation supported with continuous development of the supply section substitution quantity information processing system which the information highway is quick and the Korean railroad technical research worker propelled the enterprise as the subjective agency, it contracted this for a vehicle field information anger system construction in link of the enterprise our construction and an agreement, information technique composed the consortium t9day and it propelled a system codevelopment. The SMSC who is a front-runner of Maj loach city railroad operation agency to 'here business relates with a vehicle field maintenance conservativeness an immediacy operation and generally and information anger it will plan it will integrate it will own jointly and business efficiency and in the dictionary an obstacle occurrence electromotive car maintenance conservative information and it will improve only maintenance conservativeness of preventive maintenance of the electromotive car it knows it will prevent to construct the maintenance conservative system of the preventive maintenance, it applied the RIMS project to sleep.