• Clinical and Experimental Reproductive Medicine
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• v.51 no.3
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• pp.268-275
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• 2024

Objective: The purpose of this study was to evaluate the impact of preimplantation genetic testing for aneuploidy (PGT-A) on clinical outcomes among high-risk patients. Methods: This retrospective study involved 1,368 patients and the same number of cycles, including 520 cycles with PGT-A and 848 cycles without PGT-A. The study participants comprised women of advanced maternal age (AMA) and those affected by recurrent implantation failure (RIF), recurrent pregnancy loss (RPL), or severe male factor infertility (SMF). Results: PGT-A was associated with significant improvements in the implantation rate (IR) and the ongoing pregnancy rate/live birth rate (OPR/LBR) per embryo transfer cycle in the AMA (39.3% vs. 16.2% [p<0.001] and 42.0% vs. 21.8% [p<0.001], respectively), RIF (41.7% vs. 22.0% [p<0.001] and 47.0% vs. 28.6% [p<0.001], respectively), and RPL (45.6% vs. 19.5% [p<0.001] and 49.1% vs. 24.2% [p<0.001], respectively) groups, as well as the IR in the SMF group (43.3% vs. 26.5%, p=0.011). Additionally, PGT-A was associated with lower overall incidence rates of pregnancy loss in the AMA (16.7% vs. 34.3%, p=0.001) and RPL (16.7% vs. 50.0%, p<0.001) groups. However, the OPR/LBR per total cycle across all PGT-A groups did not significantly exceed that for the control groups. Conclusion: PGT-A demonstrated beneficial effects in high-risk patients. However, our findings indicate that these benefits are more pronounced in carefully selected candidates than in the entire high-risk patient population.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10b
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• pp.586-588
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• 2004

가정 내의 가전기기들이 디지털화되고 있고, 이것들을 네트워크로 연결하여 원격지에서 제어하는 스마트 홈 관련 기술들이 현실화되고 있다. 이러한 환경에서의 컴퓨팅을 위해서는 응용 프로그램간의 호환성 뿐 아니라 데이터의 호환성, 그리고 이종의 프로토콜간의 연동이 필수적이다 따라서 이를 위한 소프트웨어가 바로 스마트 홈 미들웨어이다. OSGi(Open Service Gateway Initiative)(8)는 장비 연결 및 제어로 얻을 수 있는 유효한 서비스나 여러 미들웨어들 간의 통합을 위한 제반 환경 제공을 목표로 하는 비 표준화 단체로써 OSGi 프레임워크 환경에서 서비스들은 서비스 게이트웨이와 서비스 번들의 life-cycle을 따라 동적으로 전개된다. 본 저자들은 SMF(Service Management framework)(9)를 사용하여 OSGi를 기반으로 한 Smart Home Service Bundle에 관해서 연구하였다.

• Microbiology and Biotechnology Letters
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• v.23 no.5
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• pp.565-572
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• 1995

The aim of the present research program was to develop a strain of actinomycetes producing extracellular cathepsin B inhibitor. Soil samples were collected from various sites in Korea and a number of actinomycetes were isolated from the soil samples by applying various physical and chemical pretreatments. An economical and effective method was developed for the screening of strains producing low molecular weight cathepsin B inhibitor, and consequently a strain (SMF28) among over 700 isolates was selected. Chemotaxonomic and numerical identification were carried out for the isolate. Fifty taxonomic unit characters were tested and the data were analyzed numerically using TAXON program. The isolate was identified as a strain of Streptomyces chromofuscus.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.203-204
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• 2006

We present and demonstrate a novel method of alternate-phase return-to-zero (RZ) signal generation and pulse-amplitude equalization simultaneously in a rational harmonic mode-locked fiber ring laser, using a dual-drive Mach-Zehnder (MZ) modulator. By adjusting the voltages applied to both arms of the modulator, the rational harmonic mode-locked pulse trains are equalized in their amplitudes. In addition to that, the amplitude-equalized pulse trains multiplying the repetition rate at ${\sim}10\;GHz$ have alternate $\pi$ phase difference between adjacent pulses. The alternate-phase RZ signal generated by the proposed method enhances transmission performance through the single-mode fiber (SMF) links without dispersion compensation.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.17 no.4
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• pp.448-452
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• 2004

The micromachined variable optical attenuator(VOA) was presented in the paper. The VOA has two single mode fiber(SMF) aligned with free space and symmetric parallel plate actuator with microshutter, which can control a amount of light by driving the actuator. In the paper, analysis on driving performances of the VOA was performed and can be reduced threshold voltage through the decreasing displacement actuating range. This paper presents a VOA that is fabricated using bosch deep silicon etching process with silicon on insulator(SOD wafer. The VOA consists of driving electrode, ground electrode, actuating microshutter, and mechanical stopper. In this VOA, actuating shutter is driven by electrostatic force and the threshold voltage is close to 28V, 46V come along with the spring width of 5${\mu}{\textrm}{m}$, 7${\mu}{\textrm}{m}$ respectively. Attenuation range is measured from 2.4㏈ to 16.7㏈.

• Proceedings of the KIEE Conference
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• 1996.11a
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• pp.439-441
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• 1996

A simple coupling method between APD(avalanche photodiode) arrays and SMF(single mode fiber) arrays on a Silicon carrier composed of V-grooves is proposed and carried out. Jacketed fibers embedded in V-grooves are used as alignment marks instead of patterned pedestals or solder bumps and a optical receiver module are packaged.

• Journal of the Optical Society of Korea
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• v.12 no.4
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• pp.244-248
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• 2008

We have evaluated the performance of strain-chirped fiber Bragg grating (FBG) based tunable dispersion compensator in a 40 Gb/s transmission link. In our proposed compensator, the value of dispersion could be changed from -353 ps/nm to -962 ps/nm by adjusting the rotation angle of the metal beam on which the FBG was mounted. In order to evaluate the effect of ripples in reflectivity and variations in passband of the FBG based dispersion compensator, transmission performance has been measured with our tunable dispersion compensator. Error-free transmission of a 40 Gb/s non-return-to-zero (NRZ) signal over conventional single-mode fiber (SMF) was achieved.

• Current Optics and Photonics
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• v.5 no.2
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• pp.121-128
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• 2021

We propose a novel, tiny optical receiver engine utilizing an all-in-one package based on embedded optics technology. The package's best transmission S21 and reflection S22 opto-electric (OE) bandwidths are 49.8 GHz and 34.9 GHz, respectively, and the reflectance of the optical engine is below -31.7 dB for all channels. The engine satisfies the MIL-STD-883G standard for reliability tests, such as mechanical and thermal shock, and vibration resistance. The sensitivity after 10 km single-mode fiber (SMF) transmission is below -8 dBm. The optical receiver engine is cost-competitive and applicable for 400G coarse wavelength division multiplexing 4 (CWDM4) 10 km optical transceivers.

• Microbiology and Biotechnology Letters
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• v.51 no.1
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• pp.59-68
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• 2023

Xylanase is an industrially relevant enzyme used for the production of xylobiose and xylose. Various methods are used to enhance the microbial yield of xylanase. In the present study, co-culturing of Bacillus subtilis and Bacillus pumilus were investigated using submerged fermentation for xylanase production, which was markedly increased when sal, sagwan, newspaper, wheat bran, and xylan were used as single carbon sources. Maximum xylanase production was reported after 5 days of incubation in optimized media at pH 7.0 and 37℃, resulting in 2.69 ± 0.25 µmol/min by coculture. The 1:1 ratio of sal and sagwan in optimized production media was shown to be suitable for xylanase synthesis in submerged fermentation (SMF). In comparison to mono-culture using B. pumilus and B. subtilis, co-culturing resulted in an overall 3.8-fold and 2.15-fold increase in xylanase production, respectively.

• Journal of Korean Society of Steel Construction
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• v.20 no.6
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• pp.807-815
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• 2008

The brittle failure where is occurred the welding position of column-beam flange of WUF-B connection that consider about a seismic detail possess a superior ductility capacity before Northridge earthquake 1994, require newly study about WUF-B connection. SAC Steel Project suggests a seismic detail to FEMA-350 by supporting of FEMA. It revise shape of weld access holes of WUF-B connection, welding processand welding material etc, In spite of these revision, AISC Seismic Provisions (2005) prescribe WUF-B connection using an only OMF. Recently in Korea, as the earthquake of about seismic intensity 5 occur, the necessity of revision for connection seismic detail comes to the front in Korea and FEMA-350 connection seismic details are going to include in KBC-2008 as it is. In this study, two column-beam connection specimens were marked by using SM490, SN490 built-up H-section, and based on WUF-B detail prescription of FEMA350. The parameters of the specimens are types of steel (SM, SN), and evaluate the capacities of structure and seismic by experiment. Finally we confirm a superior ductility capacity aboutspecimens JB-1 and JB-2, using SM490 and SN490,and these specimens had sufficient OMF and SMF seismic capacity, as indicated in AISC Seismic Provisions (2005).