• The KIPS Transactions:PartA
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• v.11A no.2
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• pp.195-202
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• 2004

This paper introduces the design or parallel Pipeline high-speed analog-to-digital converter(ADC) for the high-resolution video applications which require very precise sampling. The overall architecture of the ADC consists of 4-channel parallel time-interleaved 10-bit pipeline ADC structure a]lowing 200MSample/s sampling speed which corresponds to 4-times improvement in sampling speed per channel. Key building blocks are composed of the front-end sample-and-hold amplifier(SHA), the dynamic comparator and the 2-stage full differential operational amplifier. The 1-bit DAC, comparator and gain-2 amplifier are used internally in each stage and they were integrated into single switched capacitor architecture allowing high speed operation as well as low power consumption. In this work, the gain of operational amplifier was enhanced significantly using negative resistance element. In the ADC, a delay line Is designed for each stage using D-flip flops to align the bit signals and minimize the timing error in the conversion. The converter has the power dissipation of 280㎽ at 3.3V power supply. Measured performance includes DNL and INL of +0.7/-0.6LSB, +0.9/-0.3LSB.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.45 no.3
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• pp.60-68
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• 2008

This work describes a re-configurable 10MS/s to 100MS/s, low-power 10b two-step pipeline ADC operating at a power supply from 0.5V to 1.2V. MOS transistors with a low-threshold voltage are employed partially in the input sampling switches and differential pair of the SHA and MDAC for a proper signal swing margin at a 0.5V supply. The integrated adjustable current reference optimizes the static and dynamic performance of amplifiers at 10b accuracy with a wide range of supply voltages. A signal-isolated layout improves the capacitor mismatch of the MDAC while a switched-bias power-reduction technique reduces the power dissipation of comparators in the flash ADCs. The prototype ADC in a 0.13um CMOS process demonstrates the measured DNL and INL within 0.35LSB and 0.49LSB. The ADC with an active die area of $0.98mm^2$ shows a maximum SNDR and SFDR of 56.0dB and 69.6dB, respectively, and a power consumption of 19.2mW at a nominal condition of 0.8V and 60MS/s.

• Journal of Applied Biological Chemistry
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• v.62 no.1
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• pp.57-66
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• 2019

The ethyl acetate fraction of Bat Faeces (Ye Ming Sha: natural products used in Chinese Medicine) after fermentation (EFBF-AF) showed enhanced anti-oxidative effects in 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt assays. Fermentation of the Bat Faeces by using the crude enzyme extract from Aspergillus kawachii, significantly increased the anti-inflammatory effects. Fermented Bat Faeces markedly inhibited nitric oxide production, inducible nitric oxide synthase, and cyclooxygenase-2 expression in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. The EFBF-AF reduced the nuclear translocation of nuclear factor kappa B ($NF-{\kappa}B$) via $IKK{\alpha}$ and $I{\kappa}B{\alpha}$ phosphorylation, and decreased the phosphorylated the extracellular signal-regulated kinases (ERK) and p38 expression in LPS-treated RAW 264.7 macrophages. In addition, the EFBF-AF suppressed the expression of pro-inflammatory genes, such as interleukin-$1{\beta}$, interleukin-6, and tumor necrosis $factor-{\alpha}$. These results suggest that fermented Bat Faeces may suppress pro-inflammatory responses in LPS-stimulated RAW 264.7 macrophages cells via ERK, p38 mitogen-activated protein kinase and $NF-{\kappa}B$ signaling pathways.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.3
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• pp.46-55
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• 2016

This work proposes a 13b 100MS/s 45nm CMOS ADC with a high dynamic performance for IF-domain high-speed signal processing systems based on a four-step pipeline architecture to optimize operating specifications. The SHA employs a wideband high-speed sampling network properly to process high-frequency input signals exceeding a sampling frequency. The SHA and MDACs adopt a two-stage amplifier with a gain-boosting technique to obtain the required high DC gain and the wide signal-swing range, while the amplifier and bias circuits use the same unit-size devices repeatedly to minimize device mismatch. Furthermore, a separate analog power supply voltage for on-chip current and voltage references minimizes performance degradation caused by the undesired noise and interference from adjacent functional blocks during high-speed operation. The proposed ADC occupies an active die area of $0.70mm^2$, based on various process-insensitive layout techniques to minimize the physical process imperfection effects. The prototype ADC in a 45nm CMOS demonstrates a measured DNL and INL within 0.77LSB and 1.57LSB, with a maximum SNDR and SFDR of 64.2dB and 78.4dB at 100MS/s, respectively. The ADC is implemented with long-channel devices rather than minimum channel-length devices available in this CMOS technology to process a wide input range of $2.0V_{PP}$ for the required system and to obtain a high dynamic performance at IF-domain input signal bands. The ADC consumes 425.0mW with a single analog voltage of 2.5V and two digital voltages of 2.5V and 1.1V.

• The Journal of the Korea institute of electronic communication sciences
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• v.15 no.1
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• pp.199-204
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• 2020

With the development of IT. convergence systems are applied and operated in many different fields. A representative field among them is medical service, which develops in diverse types in combination with nano-technology and bio technology. However, there is a lack of technical innovation in terms of medical data operation and management. For example, data and documents are saved and integrated separately depending on their forms when electronic health records or data like SAM files are transmitted or kept. In other cases, such records and data are still kept after being recorded in paper. This study tries to design and implement the EMR system that makes it possible to capsulize forms of data and documents and to digitalize documents in work process as they are in terms of operation and storage. The system is expected to support efficient operation of electronic documents in the aspects of work and management.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4205-4208
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• 2013

Objective: The aim of this study was to explore change and significance of serum carcino-embryonic antigen (CEA) before and after gefitinib therapy in patients with advanced non-small-cell lung cancer (NSCLC). Methods: Forty patients with advanced NSCLCs in III~IV stages were selected as study objects given gefitinib therapy combined with routine local radiotherapy until tumor progression or intolerable toxicity. After treatment, all patients were divided into control and non-control groups according to the results of evaluation based on RECIST 1.1 (Response Evaluation Criteria in Solid Tumors in 2009). Peripheral fasting blood from all patients was collected in the early morning and serum CEA was assessed by electro-chemiluminescence immunoassay (ECLIA) before and after treatment. Before treatment, patients were divided into high CEA group (CEA level > 50 ng/mL) and low CEA group (CEA level ${\leq}$ 50 ng/mL). Adverse reactions were noted and progression-free survival (PFS) in both groups was recorded after long-term follow-up that ended in December, 2012. Results: There was no difference between control and non-control groups in CEA level before treatment (P>0.05), whereas serum CEA decreased more markedly lower in the control group after treatment (P<0.01). All patients were divided into high CEA group (26) and low CEA group (14) according to serum CEA level. There was no statistically significant difference between two groups in adverse reactions (P>0.05) but the rate in former group was lower. Additionally, survival rates at 9 and 12 months in high CEA group were clearly higher than in the low CEA group (P<0.01). Conclusions: Serum CEA level can serve as a biochemical index to evaluate the prognosis with gefitinib treatment for NSCLC.

• Fashion & Textile Research Journal
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• v.17 no.1
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• pp.116-126
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• 2015

This paper compared the properties of cosmetics depending on the shopping tendency of female consumers in Korea and China. The data on Chinese women living in Korea and Korean women in their 20s was collected using an offline survey. The data on Chinese women living in China in their 20s was collected using an online survey. Three hundred twenty-seven questionnaires out of a total of 330 questionnaires were used for statistical analysis. The survey was conducted from January to February 2014. Eighteen questions on shopping tendency and eight questions on the properties of cosmetics were analyzed using a 5-point Likert scale. Data was analyzed by Descriptives, Factor Analysis, Reliability Analysis, ANOVA and Cluster Analysis, and SPSS 21 statistical program. In accordance with the analyses, the shopping tendency comprised a showing-off tendency, pleasure-seeking tendency, and practicality tendency; the properties of cosmetics were classified into conformity and functionality. On the basis of the elements in the shopping tendency, the female consumers were categorized into a low involvement consumer group, high involvement consumer group, and hedonic consumer group. The Chinese women emphasized conformity or functionality of cosmetics more than the Korean women regardless of the countries where they lived. Regardless of shopping types or countries where they lived, the Korean and Chinese women in their 20s emphasized functionality over conformity of cosmetics. Furthermore, Chinese women living in Korea showed a similar shopping tendency to Chinese living in China.

• Journal of Internet Computing and Services
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• v.11 no.4
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• pp.23-32
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• 2010

In this paper, we first propose the security enhancing of authentication protocol for Hash based RFID tag, and then a digital Codec for RFID tag is designed based on the proposed authentication protocol. The protocol is based on a three-way challenge response authentication protocol between the tags and a back-end server. In order to realize a secure cryptographic authentication mechanism, we modify three types of the protocol packets which defined in the ISO/IEC 18000-3 standard. Thus active attacks such as the Man-in-the-middle and Replay attacks can be easily protected. In order to verify effectiveness of the proposed protocol, a digital Codec for RFID tag is designed using Verilog HDL, and also synthesized using Synopsys Design Compiler with Hynix $0.25\;{\mu}m$ standard-cell library. Through security analysis and comparison result, we will show that the proposed scheme has better performance in user data confidentiality, tag anonymity, Man-in-the-middle attack prevention, replay attack, forgery resistance and location tracking.

• Journal of Ginseng Research
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• v.40 no.4
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• pp.344-350
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• 2016

Background: Mountain-cultivated ginseng (MCG) and cultivated ginseng (CG) both belong to Panax ginseng and have similar ingredients. However, their pharmacological activities are different due to their significantly different growth environments. Methods: An ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS)-based approach was developed to distinguish MCG and CG. Multivariate statistical methods, such as principal component analysis and supervised orthogonal partial-least-squares discrimination analysis were used to select the influential components. Results: Under optimized UPLC-QTOF-MS/MS conditions, 40 ginsenosides in both MCG and CG were unambiguously identified and tentatively assigned. The results showed that the characteristic components of CG and MCG included ginsenoside Ra3/isomer, gypenoside XVII, quinquenoside R1, ginsenoside Ra7, notoginsenoside Fe, ginsenoside Ra2, ginsenoside Rs6/Rs7, malonyl ginsenoside Rc, malonyl ginsenoside Rb1, malonyl ginsenoside Rb2, palmitoleic acid, and ethyl linoleate. The malony ginsenosides are abundant in CG, but higher levels of the minor ginsenosides were detected in MCG. Conclusion: This is the first time that the differences between CG and MCG have been observed systematically at the chemical level. Our results suggested that using the identified characteristic components as chemical markers to identify different ginseng products is effective and viable.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.3
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• pp.485-492
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• 2008

Computers used fer light-weight computing environments are considerably limited in resources and performance running in ubiquitous environment. Because of the limited resources, it is difficult to apply existing security technologies to the light-weight computers. In this paper, light-weight security software is implemented using RC-5 encryption and SHA-1 authentication algorithm which is appropriate for light-weight computing environments. The design of components based on security software of a light-weight computer application and the test-bed for security software are presented. The simulation verifies the correctness of the security software. The architecture of the light-weight and reconfigurable security software for light-weight computer applications is proposed. The proposed security software is small size and provides reconfigurable security library based on the light-weight component and the software manager that configures software platform is loaded with the library at the time it is needed.