• Journal of Preventive Medicine and Public Health
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• 제51권5호
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• pp.242-247
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• 2018

Objectives: To examine survivorship disparities in demographic factors and risk status for non-muscle-invasive bladder cancer (NMIBC), which accounts for more than 75% of all urinary bladder cancers, but is highly curable with early identification and treatment. Methods: We used the US National Cancer Institute's Surveillance, Epidemiology, and End Results registries over a 19-year period (1988-2006) to examine survivorship disparities in age, sex, race/ethnicity, and marital status of patients and risk status classified by histologic grade, stage, size of tumor, and number of multiple primary tumors among NMIBC patients (n=29 326). We applied Kaplan-Meier (K-M) and Cox proportional hazard methods for survival analysis. Results: Among all urinary bladder cancer patients, the majority of NMIBCs were in male (74.1%), non-Latino white (86.7%), married (67.8%), and low-risk (37.6%) to intermediate-risk (44.8%) patients. The mean age was 68 years. Survivorship (in median life years) was highest for non-Latino white (5.4 years), married (5.4 years), and low-risk (5.7 years) patients (K-M analysis, p<0.001). We found significantly lower survivorship for elderly, male (female hazard ratio [HR], 0.96), Latino (HR, 1.20), and unmarried (married HR, 0.93) patients. Conclusions: Survivorship disparities were ubiquitous across age, sex, race/ethnicity, and marital status groups. Non-white, unmarried, and elderly patients had significantly shorter survivorship. The implications of these findings include the need for a heightened focus on health policy and more organized efforts to improve access to care in order to increase the chances of survival for all patients.

• 한국가정과교육학회지
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• 제15권3호
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• pp.1-12
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• 2003

이 연구는 가정과 교사들에게 창의적 재량활동 프로그램 개발을 위한 기초 자료를 제공하고자 서울시내 중학생 521명을 대상으로 실시 하였다. 청소년 발달 특성을 기초한 자기 자신에 대한 이해, 진로 탐색, 가족 관계,동료간의 우정, 성에 대한 이해, 예절 영역의 요구도 척도를 개발하여 조사 분석한 결과는 다음과 같다. 첫째, 중학생을 대상으로 창의적 재량활동 범교과 학습에 대하여 자기 자신에 대한 이해, 진로 탐색이 가장높은 요구도를 보였으며 다음으로 가족관계, 동료 간의 우정, 청소년의 부적응, 예절, 성에 대한 이해 순으로 나타났다. 둘째, 창의적 재량활동 범교과 학습 요구도의 문항내용을 분석해본 결과 자기 자신에 대한 이해 영역의 모든 문항과 나의 잠재 능력 찾기, 나의 적성에 대하여 알아보기 등이 4점 이상의 높은 요구도를 나타내었다. 아울러 3.5점 이상을 나타낸 것은 나의 흥미 알아보기, 변화하는 사회와 직업, 새로운 직업 건전한 직업 가치관, 삶의 목표, 나의 미래 모습, 가족 간의 사랑 일깨우기, 생활 속의 예절 등이다. 셋째, 사회인구학적인 변인에 따른 중학교 2학년 학생들의 창의적 재량활동 범교과 학습 요구도를 알아본 결과 성별, 가족유형, 경제수준 등에 따라 유의미한 차이를 나타내었다.

• Animal cells and systems
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• 제5권3호
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• pp.237-241
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• 2001

Three STR loci (STRX1[AGAT]$_{n}$, HPRTB[AGAT]$_{n}$ and ARA[AGC]$_{n}$) on X chromosome and three other STR loci (DYS390[CTG(A)T]$_{n}$, DYS392[ATT]$_{n}$ and DYS39［GATA]$_{n}$) on Y chromosome were analyzed in 154 unrelated healthy Korean subjects. Four loci (STRX1, HPRTB, DYS390 and DYS393) were amplified by quadruplex polymerase chain reaction (PCR) using fluorescent labeled primers (FLP). ARA and DYS392 were amplified separately using single PCR, similarly by using FLP. They were then run in an automated DNA sequencer and were analyzed with Genescan software. We found 7 alleles (308-332 bp) in STRX1, 7 alleles (275-299 bp) in HPRTB, 16 alleles (252-315 bp) in ARA, 6 alleles (203-223 bp) in DYS390, 7 alleles (245-263bp) in DYS392 and 5 alleles (116-132 bp) in DYS393. The ＊13(34%), ＊13(5l%), ＊23 (l8%), ＊23(50%), ＊14(39%) and ＊13(40%) alleles were observed to be the highest frequencies of STRX1, HPRTB, ARA, DYS390, DYS392 and DYS393, respectively. The detection of STR loci on sex chromosomes by quadruplex PCR allows simple determination of sex and identification of an individual. individual.

• 한국학교ㆍ지역보건교육학회지
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• 제2권1호
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• pp.53-65
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• 2001

The purposes of this study were to collect basic data on education of Sexuality(Health education) of consciousness & value of sexuality of elementary school children. 584,6th grade students in elementary school in Yong-In city were analysed and the results are as follow; 1. Knowledges of sexuality for children was at a average level, especially "physical change of puberty" and "sexual violence" were well recognized but "the physical characteristics of male & female" and "physiological phenomena of men" were less recognized. Attitudes of sexuality were positive for "relationship with partners" and "expression of mind". Practices of sexuality were at a low rate in the case of "shaking hands with partner" and "experience of sexual behavior". The Value of sexuality was at a high rates in the case of "the role of sex", "equality" & "self-identification", therefore students need good education of sexuality from childhood 2. Sexuality education of students increased knowledges of sexuality as a consciousness. There was no relationship between attitudes and pratices of sexuality. Educated children valued sexuality move highly than uneducated children. This result shows that education is needed with regard to both the knowledge and value of sexuality in a planned system. We need some program to provide more information on sexual attitudes and practices. 3. There was a high correlation between the consciousness of sexuality and value placed on it. As sexual awareness increases amongst students codes of morality develop Positive sexual attitudes served as good role models for sex. In particular positive sexual attitudes have a big effect on sexual values. In addition, as sexual awareness and attitude increase amongst students the role of sexual development. The elementary school phase sexual values are developed and determined. It is therefore an important phase.

• Animal Bioscience
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• 제36권5호
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• pp.704-709
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• 2023

Objective: In tropical, subtropical and arid zones, heat stress is the main cause of productivity reduction in cattle. When climate stressors occur, animals become thermal adapted through differential expression of some genes, including heat shock proteins (HSP) family. The aim of this study was to determine levels of expression of HSP60, HSP70, and HSP90 genes in Simmental cattle raised in tropical environments of Mexico. Methods: In this study, expression of HSP60, HSP70, and HSP90 genes was analyzed in 116 Simmental cattle from three farms with tropical climate located in western Mexico. Animals were sampled twice a day, in the morning and noon. Gene expression was evaluated by quantitative polymerase chain reaction using probes marked with fluorescence. The MIXED procedure of SAS with repeated measures was used for all statistical analysis. Results: HSP60 gene expression differences were found for sex (p = 0.0349). HSP70 gene differences were detected for sampling hour (p = 0.0042), farm (p<0.0001), sex (p = 0.0476), and the interaction sampling hour×farm (p = 0.0002). Gene expression differences for HSP90 were observed for farm (p<0.0001) and year (p = 0.0521). HSP70 gene showed to be a better marker of heat stress than HSP60 and HSP90 genes. Conclusion: Expression of HSP70 gene in Simmental herds of the tropical region of western México was different during early morning and noon, but the expression of the HSP60 and HSP90 genes was similar. Identification of resilient animals to heat stress will be useful in the genetic improvement of the Simmental breed.

• 한국환경생태학회지
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• 제34권1호
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• pp.1-8
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• 2020

본 연구는 오대산국립공원에 서식하는 산양의 정확한 서식 실태를 파악하는 한편, 개체군 증가에 따른 복원과 서식지 관리 중심의 보전사업을 위한 무인센서카메라를 이용한 산양의 개체 수 전수조사를 실시하였다. 오대산국립공원에서 2018년 1년간 현장조사를 통해 획득한 산양 서식실태 조사결과를 중심으로 산양의 서식 흔적이 가장 많이 관찰된 18개의 격자(2km×2km)를 우선 선정한 후 다시 4개의 소격자(1km×1km)로 나누어 38개의 소격자에 총 62대의 무인센서카메라를 설치하여 조사를 진행하였다. 조사결과, 총 5,096장의 야생동물이 촬영되었고, 이중 산양은 총 2,268장이 촬영되었으며, 산양 분류표(뿔 형태 Ⓐ, 링 무늬Ⓑ, 링 형성 비율Ⓒ, 얼굴 색상 Ⓓ)로 분석한 결과 총 95개체를 확인하였다. 암·수 비율은 수컷 35개체(36.8%), 암컷 46개체(48.4%), 성별미상(새끼) 14개체(14.7%)로 나타났으며, 성별미상을 제외한 암·수 비율은 4(수):6(암)비율로 나타났다. 산양의 개체 수 분석 중 뿔 형태 Ⓐ와 얼굴 색상 Ⓓ로 암·수 및 개체가 확연이 구분되어 각 개체를 구분하는 중요한 요인이었으며, 성별미상인 14개체를 제외한 81개체의 상관관계를 분석한 결과(r=-0.635, p<0.01) 유의적인 차이가 나타났으며, 오대산국립공원의 산양은 최소생존개체군을 형성하였기에 복원에서 보전으로 정책의 변화가 필요하다.

• 한국가금학회지
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• 제51권2호
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• pp.65-71
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• 2024

병아리의 성 감별 방법으로 깃털 감별법이 상업적으로 가장 널리 이용되고 있다. 그러나 깃털 감별법이 산업적으로 실용화되기 위해서는 종계의 기초 계군 내 조우성과 만우성 유전자가 존재하고, 깃털 감별이 될 수 있는 종계 계통을 조성하여야 하고, 깃털 감별로서 병아리의 성 판별율이 정확하여야 한다. 따라서 본 연구에서는 상업용 토종닭의 깃털 감별을 위한 자가 성감별 종계 계통 조성 방법과 조성된 종계로써 생산한 상업용 병아리들의 깃털 성 판별의 유효성을 소개하고자 하였다. 깃털 감별용 종계 조성을 위한 기초 계군은 조우성 개체와 만우성 개체가 혼재되어 있었으며, 만우성유전자의 빈도가 0~0.205 정도로 추정되었다. 병아리의 깃털 자가 성감별을 위한 계통 조성으로 원종계의 부 계통은 암수 공히 조우성(kk)으로 고정하고, 모 계통의 부는 만우성 동형접합체(Z^KZ^K)를 가진 계군으로, 모는 조우성(Z^kW)을 가진 계군으로 조성하였다. 따라서 부계 종계는 조우성(Z^kZ^k), 모계 종계는 만우성(Z^KW)으로 되어 이들 간 교잡으로 생산된 병아리들은 수컷은 만우성(Z^KZ^k), 암컷은 조우성(Z^kW)을 가지므로 병아리의 깃털 형태로써 암수를 감별할 수 있었다. 또한 생산된 실용 병아리에 대한 깃털 감별의 유효성을 살펴보고자 생산 병아리 중 1,000수를 표본으로 항문 감별과 깃털 감별 간의 감별 일치도를 조사한 결과 일치율은 93.1%로 나타났다.

• 동의생리병리학회지
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• 제29권3호
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• pp.230-239
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• 2015

This study was performed to find a relationship between each pattern identification and vascular status using the second derivative of photoplethysmogram waveform(SDPTG) indices. We analyzed 200 subjects who participated in stroke preventive examination. We classified the subjects into four groups of pattern identifications; Fire-Heat pattern(火熱證; FH), Yin Deficiency pattern(陰虛證; YD), Qi Deficiency pattern(氣虛證; QD) and Dampness-Phlegm pattern(濕痰證; DP) that based on Korean Standard Pattern Identifications for Stroke-Ⅲ. We studied a relationship between each pattern identification and the SDPTG. The total number of the subject group was 200, whereas the groups were divided into four groups; Fire-Heat pattern group(n=49), Yin Deficiency pattern(n=57), Qi Deficiency pattern(n=45), and Dampness-Phlegm pattern(n=49). b/a ratio was related with age and systolic blood pressure, c/a ratio was associated with age, systolic blood pressure, fasting blood sugar and Total cholesterol, d/a ratio was affected with age, diastolic blood pressure, and hypertension, e/a ratio was related with age and sex and SDPTG AI was associated with age. c/a ratio and d/a ratio were significantly higher in the Fire-Heat group than in the Qi Deficiency group. SDPTG AI was significantly higher in the Qi Deficiency group than in the Fire-Heat group. The Qi Deficiency group was significantly older than the Fire-Heat group and the number of hypertension patients was significantly more in the Fire-Heat group than in the Qi Deficiency group. Through this study, we found out some significant relationships between each pattern identification group and the SDPTG indices.

• 대한미생물학회지
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• 제20권1호
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• pp.35-44
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• 1985

Isolation and identification of anaerobic bacteria from blood cultures are still technically demanding procedures. Recently, with the use of gas liquid chromatography, the accuracy of identification is much improved. However, there has never been a satisfactory data analysis on anaerobic bacteremia in Korea. The authors evaluated both the clinical and the bacteriological data of 129 anaerobic bacteremias found at the Yonsei Medical Center during the period of 1973 to 1984. The most frequently isolated anaerobic bacteria were Bacteroides (52.7%), among which the major species was B. fragilis (38.7%). Incidence of anaerobic bacteremia by sex was 57% in male and 43% in female. Mortality was higg in groups below 1-year old and above 50-year old. The cause of death seemed closely correlated with the patient's age, general condition and the severity of the underlying disease. Various neoplasms were the most common (20%) underlying diseases predisposing the anaerobic bacteremia. Biliary tract was considered the most frequent route of infection in anaerobic bacteremia. The frequent clinical signs in anaerobic bacteremia were fever (65%), followed by liver function abnormality (29%), jaundice (20%) and hypotention(18%). When analysis of positive rate of blood culture was made on the patients from whom 4 cultures were done within 24 hours, it was found that 33% of the samples were positive. Isolation rate of anaerobic bacteria in thioglycollate medium was 83.8%, while it was 44% in Tryptic soy broth. Among the anaerobic bacteremia, 25.4% were polymicrobial infections with aerobic bacteria (92.5%), such as E. coli(33.3%). From these studies, it is concluded that B. fragilis is the most important causative organism in anaerobic bacteremia, with high fatality, particularly in those who have underlying diseases. The ports of entry are mainly biliary, gastrointestinal and female genital tract. Fever is the most frequent clinical sign. Single blood culture is not sufficient to detect all anaerobic bacteremia, therefore more cultures with optimal time interval are needed. The incidence of polymicrobial infection in anaerobic bacteremia is higher than that in overall bacteremia.

• 전자공학회논문지S
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• 제35S권6호
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• pp.88-100
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• 1998

본 논문에서는 지문 영상의 개별적이고 부분적인 특성(밝기, 품질 차이 등)을 고려하여 지문의 특징량 추출을 수행함으로써 지문 입력기간의 차이에서 오는 문제점을 극복하며, 정합 과정시에는 회전 및 크기 변화, 위치 이동 등에 관계없이 균일한 성능을 보장하면서도 실시간 내에 처리가 가능한 자동 지문인식 알고리즘을 제안한다. 특히 본 방법에서는 지문의 분류 작업을 융선의 전체적인 흐름 모양과 중심점, 삼각주와 같은 특이점간의 상호 관계를 이용하여 결정하게 된다. 개발된 알고리즘을 평가하기 위해 NIST 지문 및 한국인의 연령과 직업별 인구 분포에 따라 구축된 압착 날인 지문, 그리고 회전 날인 후 수치화된 지문과 같은 다양한 영상들에 대해 제안된 방법을 적용하였으며, 전체적인 인식 성능이 타인 수락 오류율을 0%로 설정했을 때 본인 거부 오류율이 0.07%라는 결과를 얻을 수 있었다.