• Title/Summary/Keyword: SDM

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Evaluation of Optimal Culture Conditions for Recombinant Ghost Bacteria Vaccine Production with the Antigen of Streptococcus iniae GAPDH

  • Ra, Chae-Hun;Kim, Yeong-Jin;Park, So-Jin;Jeong, Chang-Wha;Nam, Yoon-Kwon;Kim, Ki-Hong;Kim, Sung-Koo
    • Journal of Microbiology and Biotechnology
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    • v.19 no.9
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    • pp.982-986
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    • 2009
  • For the production of ghost bacteria vaccine to prevent the streptococcal disease in aquaculture fish species, a double cassettes vector was constructed and cloned in Escherichia coli DH5${\alpha}$. Ghost bacteria vaccine production from Escherichia coli DH5${\alpha}$/pHCE-InaN-GAPDH-Ghost 37 SDM (SIG) was maximized at a glucose concentration of 1 g/l, agitation of 300 rpm, and aeration of 1 vvm. The maximal efficiency of ghost bacteria formation was obtained at the mid-exponential phase ($OD_{600}=2.0$) with the concentration of 0.77 g/l for SIG. The molecular mass of GAPDH was detected at 67 kDa with the insoluble fraction, by SDS-PAGE and Western blot. The protective efficacy of ghost bacteria vaccine was evaluated by challenge test using olive flounder. The cumulative mortalities of the positive control, formalin-killed cell (FKC) vaccine, and SIG vaccine immunized groups were 91%, 74%, and 57%, respectively. These results suggest that SIG vaccine showed efficacy as a vaccine and had a higher potential to induce protective antibodies than did FKC vaccine.

A Study on the Dynamic Characteristics of Door Module for Vehicle (자동차용 모듈화 도어의 동특성 분석에 관한 연구)

  • Bae, Chul-Yong;Kim, Chan-Jung;Kwon, Seong-Jin;Lee, Bong-Hyun;Jang, Woon-Sung;Lee, Joon-Woo
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.17 no.11
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    • pp.1093-1101
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    • 2007
  • This study presents the design improvement process for door module. Its objective evades the resonance generated at module plate due to the operation of window regulator motor. For this study, the design improvement process is composed of experimental methods having three steps. First step is modal analysis at door assembly status for acquisition of dynamic characteristics which are modal frequency and damping. Second step is a vibration experiment to get the test mode considered an efficiency of window regulator motor. Last step is a vibration measurement by the form of $6{\times}6$ array on module plate. A vibration measurement of $6{\times}6$ array form can be got to three analysis results which are a transfer path of vibration using cross correlation function, a vibration map using OA level and a contribution by frequency band using coherent output power spectrum on module plate. These results are applied to SDM(structural dynamic modification) for design improvement to get around the resonance on module plate by the excitation of window regulator motor.

The Subjective Response for Impulsive Sound - Focusing on the Construction Noise - (충격성 소음에 대한 주관적 반응 - 건설공사장 소음을 중심으로 -)

  • Kim, Deuk-Sung;Chun, Hyung-Jun;Chang, Seo-Il
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.18 no.7
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    • pp.746-755
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    • 2008
  • This research presents a laboratory study on subjective response of impulsive sound caused by construction site (breaker and blasting). The sources are sampled from outdoor noise and their levels range from 40 to 75 dBA at the interval of 5 dBA. The noise unit is based on A-weighted sound exposure level(ASEL; $L_{AE}$). To make equal ASEL of listening level, finite impulse response(FIR) filter is applied to the originally sampled source to include the effect of propagation attenuation. Sixty-three subjects, forty-two males and twenty-one female, between 18 and 29 years of age, participated in the experiment. The evaluation method of jury test adopted a semantic difference method(SDM). In the test results for impulsive noise, the subjective response of blasting noise was higher than that of breaker noise. The result of %HA that has been combined responses of the three methods except for pink-noise was executed by regression analysis and was shown as the following equation.: $%HA=746.53/(1+{\exp} (L_{AE}-93.3))+0.34$.

Interpolated Digital Delta-Sigma Modulator for Audio D/A Converter (오디오 D/A 컨버터를 위한 인터폴레이티드 디지털 델타-시그마 변조기)

  • Noh, Jinho;Yoo, Changsik
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.11
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    • pp.149-156
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    • 2012
  • A digital input class-D audio amplifier is presented for digital hearing aid. The class-D audio amplifier is composed of digital and analog circuits. The analog circuit converts a digital input to a analog audio signal (DAC) with noise suppression in the audio band. An interpolated digital delta-sigma modulator is used to convert data types between digital signal processor (DSP) and digital-to-analog converter (DAC). An 16-bit, 25-kbps pulse code modulated (PCM) input is interpolated to 16-bit, 50-kbps by a digital filter. The output signal of interpolation filter is noise-shaped by a third-order digital sigma-delta modulator (SDM). As a result, 1.5-bit, 3.2-Mbps signal is applied to simple digital to analog converter.

The Influence of Cognitive Function, Pain, and Body Image on the Activities of Daily Living in Patients with Brain Injury (뇌손상 환자의 일상생활수행에 대한 인지기능, 통증 및 신체상의 영향)

  • Kim, Mi Reyung;Suh, Yeonok
    • The Korean Journal of Rehabilitation Nursing
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    • v.20 no.1
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    • pp.33-41
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    • 2017
  • Purpose: This study is a descriptive study to analyze the relationship between the cognitive function, body image and pain, and the influencing factors on the daily life performance of brain injured patients. Methods: The study subjects were 119 inpatients with brain injury who gave informed consent. The activities of daily living (ADLs), cognitive function, pain and body image were measured by Modified Barthel Index (K-MBI), K-MMSE (Mini-Mental State Examination), Visual Analog Scale (VAS), Semantic Differential Method (SDM), respectively. Results: ADLs was significantly associated with body image, cognitive function, and pain. Multiple regression analysis showed that paralysis, consciousness, cognitive function, and pain were significant factors influencing ADLs. Overall, approximately 48% of total variability in the ADLs could be explained by the 4 variables ($R^2=.477$, p<.001). Conclusion: To improve ADLs of brain injury patients, a deeper understanding of paralysis, consciousness, cognitive function, and pain of patients is required and active nursing invention should be conducted.

A Study on the Structural Dynamic Modification of sub-structure of Clean Room using VSD System (반도체 크린룸 구조물의 하중 측정 시스템을 이용한 동특성 개선에 관한 연구)

  • 백재호;이홍기;손성완
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2003.05a
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    • pp.1099-1106
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    • 2003
  • 진동에 민감한 각종 정밀장비를 갖추고 있는 공장구조물은 설립하는 설계 초기단계에서부터 정밀장비가 정상 운용을 위하여 공장구조물의 진동허용규제치 및 동특성허용규제치를 결정해야 한다. 이를 만족할 수 있도록 공장구조물 설계시 진동측면에 대하여 동적 특성을 검토해야만 한다. 이때 반드시 필요한 자료로 정밀장비 Maker에게서 제공되는 진동허용규제치 및 구조물의 동특성허용규제치 등 설치시방의 상세한 자료를 제공받아야 한다 이러한 선계조건을 만족시켜주기 위한 방안으로 외부에서 정밀장비로 유입되는 진동에 대한 진동절연을 위하여 진동전달률 이론을 적용하여 방진효율 산출하는 방법과 정밀장비에서 발생하는 동하중을 고려하여 공장구조물에 대한 동적설계를 수행하는 것으로, 구조물 동특성을 요구되는 만큼 구조물 동특성 변경 SDM(Structural Dynamic Modifacation)방법이 주로 활용된다. 이에 본 연구에서는 앞서 언급한 구조물의 동적설계시 후자조건인 구조물의 동특성을 변경하고자 하는 경우에 실구조물에 하중을 정량적으로 조절하며 가할 수 있는 VSD 시스템을 이용하여 구조물의 동특성을 변화시키는 것을 동적해석으로 예측하였고, 현장에서 실제 동적실험으로 구한 결과를 동적설계 목표치와 비교하여 유용성에 대하여 확인하였다.

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A Study on Keratinized Gingival Thickness in Healthy Korean Adults (한국 성인의 각화치은 두께측정에 관한 연구)

  • Kang, Chul-Heun;Chang, Moon-Taek;Ryu, Sung-Hoon;Kim, Hyung-Seop
    • Journal of Periodontal and Implant Science
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    • v.30 no.1
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    • pp.179-187
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    • 2000
  • The objectives of this study were to measure keratinized gingival thickness in healthy Korean adults, and to correlate the keratinized gingival thickness with width of keratinized gingiva, probing pocket depth and gingival recession.Thickness measurements were performed in 37 Korean dental students using an ultrasonic device(SDM). Width of keratinized gingiva, gingival recession and probing pocket depth were measured with a Williams periodontal probe.The results showed that the keratinized gingival thickness varied from 0.83 mm(canines) to 1.16 mm(central incisors) in the maxilla and, in the mandible, from 0.68 mm(1st premolars) to 1.69 mm(2nd molars). In a stepwise multiple linear regression analysis, 23% of variation of gingival thickness could be explained by width of keratinized gingiva and probing pocket depth. It could be concluded that the keratinized gingival thickness depends on tooth type and correlates with width of keratinized gingiva and probing pocket depth.

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Performance Improvement of a Buck Converter using a End-order Space Dithered Sigma-Delta Modulation based Random PWM Switching Scheme (2차 Space Dithered Sigma-Delta Modulation 기반의 Random PWM 스위칭 기법을 이용한 강압형 DC-DC 컨버터의 성능 개선)

  • Kim, Seo-Hyeong;Ju, Seong-Tak;Jung, Hea-Gwang;Lee, Kyo-Beum;Jung, Gyu-Bum
    • The Transactions of the Korean Institute of Power Electronics
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    • v.14 no.1
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    • pp.54-61
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    • 2009
  • This paper proposes the 2nd-order SDSDM (Space Dithered Sigma-Delta Modulation) for performance improvement of a buck converter. The PWM (Pulse Width Modulation) has a drawback in that power spectrum tends to be concentrated around the switching frequency. The resulting harmonic spikes cause a EMI(Electromagnetic Interference) and switching loss in semiconductor, etc. The 1st-order SDSDM scheme is a kind of DSDM for reducing these harmonic spikes. In this scheme, a switching frequency is spread through random dither generator placed on input part. In experimental result, the proposed 2nd-order SDSDM is confirmed by applying to a buck converter.

Electro-Osmotic Dewatering under Electro-Osmotic Pulse Technology

  • Kim, Jitae;Lee, Jeongwoo;Chung, Il-Moon
    • The Journal of Engineering Geology
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    • v.30 no.4
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    • pp.423-433
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    • 2020
  • Direct current (DC) electric fields have been used for electro-osmotic dewatering. Under DC conditions, however, the electrical contact resistance between the electrode and the dewatering material increases considerably during the process of dewatering. Such a circumstance hinders the continuation of effective electro-osmotic dewatering. To reduce this hindrance, an applied pulse electric field with periodic reversals of the electrode polarity should improve electro-osmotic dewatering. In this study, electro-osmotic dewatering under pulse conditions was experimentally investigated for electrode polarity reversals. During the dewatering process, the pulse electric field was able to reduce the hindrance caused by the DC, resulting in an increased final dewatered amount relative to that under a DC electric field. For a constant applied voltage, the reversed polarity condition, under which the electric current passing through the material was almost unchanged with time, yielded the maximum final dewatered amount. This technique can be used to enhance drainage from a water storage facility during a period of extreme drought and the seawater desalination plants using reverse osmosis in drought stricken coastal regions.

Does Financial Behavior Influence Financial Well-being?

  • CHAVALI, Kavita;MOHAN RAJ, Prasanna;AHMED, Riyaz
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.2
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    • pp.273-280
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    • 2021
  • Financial behavior and financial well-being are two closely related aspects of an individual's financial decision making. This study attempts to investigate the extent to which financial behavior influences financial well-being in the Indian scenario. The data is collected using a structured questionnaire from a sample of 150 respondents. The study employs Financial Management Behaviour Scale (FMBS) (Dew & Xiao, 2012) to measure financial behavior. Factor analysis and multiple regression are performed to find the influence of financial behavior on financial well-being. The findings of the study suggest that except for credit commitment all the other behavioral factors like future security, savings and investments, credit indiscipline, and financial consciousness have a significant impact on the financial well-being of an individual in the Indian scenario. The regression coefficients of financial well-being are strongly determined by financial consciousness. The study is a contribution to the existing behavioral studies literature and the model used identifies the factors that influence the financial well-being in the Indian scenario. The study is conducted during the year 2020, so the results could have been influenced by the economic scenario of the period. The results of the study can be used by financial advisors to understand the financial well-being in the Indian scenario.