• Journal of Microbiology and Biotechnology
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• 제34권9호
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• pp.1912-1918
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• 2024

Single-cell protein (SCP) derived from microorganisms is widely recognized as a viable alternative protein source for the future. Nevertheless, the commercialization of yeast-based SCP is hampered by its relatively low protein content. Therefore, this study aimed to enhance the protein content of Saccharomyces cerevisiae via random mutagenesis. To achieve this, S. cerevisiae KCCM 51811, which exhibited the highest protein concentration among 20 edible S. cerevisiae strains, was selected as a chassis strain. Subsequently, a KCCM 51811 mutant library was constructed (through UV irradiation) and screened to isolate mutants exhibiting high protein content and/or concentration. Among the 174 mutant strains studied, the #126 mutant exhibited a remarkable 43% and 36% higher protein content and concentration, respectively, compared to the parental strain. Finally, the #126 mutant was cultured in a fed-batch system using molasses and corn-steep liquor, resulting in a protein concentration of 21.6 g/l in 100 h, which was 18% higher than that produced by the parental strain. These findings underscore the potential of our approach for the cost-effective production of food-grade SCP.

• 한국재료학회지
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• 제12권10호
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• pp.784-790
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• 2002

For mass product of nanocrystalline ZnO ultrafine powders, self-sustaining combustion process(SCP) and ultrasonic spray combustion method(USCM) were applied at the same time. Ultrasonic spray gun was attached on top of the vertical type furnace. The droplet was sprayed into reaction zone of the furnace to form SCP which produces spherical shape with soft agglomerate crystalline ZnO particles. To characterize formed particles, fuel and oxidizing agent for SCP were used glycine and zinc nitrate or zinc hydroxide. Respectively, with changing combustion temperature and mixture ratio of oxidizing agent and fuel, the best ultrasonic spray conditions were obtained. To observe ultrasonic spray effect, two types of powder synthesis processes were compared. One was directly sprayed into furnace from the precursor solution (Type A), the other directly was heated on the hot plate without using spray gun (Type B). Powder obtained by type A was porous sponge shape with heavy agglomeration, but powder obtained using type B was finer primary particle size, spherical shape with weak agglomeration and bigger value of specific surface area. 9/ This can be due to much lower reaction temperature of type B at ignition time than type A. Synthesized nanocrystalline ZnO powders at the best ultrasonic spray conditions have primary particle size in range 20~30nm and specific surface area is about 20m$^2$/g.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1992년도 가을학술발표회 논문집
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• pp.149-155
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• 1992

In case of construction of the final refuse disposal site on the ground where 20m soft clay layer is deposited, Sand Compaction Pile(SCP) was driven with a view to increase the strength and reduce the settlement when the reclaimed revetment intend to be constructed first in a short time. Field monitoring method is carried out in order to overcome the problems of settlement and stability in the construction of the reclaimed revetment and the assumed problems in the design of composite ground. In this paper the observed data from monitoring sections are analysed, fedback to the desigh and field, and compared with FEM analysis. Conclusions are as follow: in case of 70% replacement the use of modified soilparameters makes the FEM analysis of SCP possible. In case of 27% replacement, n(stress concentration ratio)=0.2-0.3, B(measured settleme reduction coefficient)=0.43 are evalated. Also, horizontal displacement is remarkably happened around the ground.

• 한국영양학회:학술대회논문집
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• 한국영양학회 2003년도 연합학술대회
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• pp.198.2-198.2
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• 2003

• 전기전자학회논문지
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• 제20권4호
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• pp.439-448
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• 2016

온도 측정을 위해 RTD와 열전대 센서가 산업이나 연구 분야에 널리 사용되고 있다. RTD 및 열전대의 온도 교정기에 대한 표준교정절차는 측정에서 포함되는 불확도의 교정 결과를 나타내는 방법을 보여준다. 지금까지 이들에 대한 표준교정절차가 확립되지 않아 다소의 불편함과 표준교정 업무에 어려움이 있었다. 이러한 문제를 해결하기 위해 온도 교정기의 RTD 및 열전대에 대한 교정기법을 연구하게 되었다. 본 논문에서는 이들에 대한 수학적 모델과 교정결과 자료를 제시하였다.

• Journal of Welding and Joining
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• 제20권6호
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• pp.802-808
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• 2002

Front-side members are structures with the greatest energy absorbing capability in a front-end collision of vehicles. This paper was performed to analyze initial collapse characteristics of spot welded hat and double hat-shaped section members, which are basic shape of side members, on the shift of flange weld pitches. The impact collapse tests were carried out by using home-made vertical air compression impact testing machine, and impact velocity of hat-shaped section members is 4.17m/sec and that of double hat-shaped section members is 6.54m/sec. In impact collapse tests, the collapsed length of hat-shaped section members was about 45mm and that of double hat-shaped section members was about 50mm. In consideration of these condition, axial static collapse tests(0.00017m/sec) of hat and double hat-shaped section members were carried out by using UTM which was limited displacement, about 50mm. As the experimental results, to obtain the best initial collapse characteristics, it is important that stiffness of vehicle members increases as section shapes change and the progressively folding mode induces by flange welding pitch.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권1호
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• pp.45-51
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• 2015

Objectives : Children with attention-deficit hyperactivity disorder (ADHD) have been shown to display more inhibitory deficits and executive function deficits. This study investigated the treatment effects of neurofeedback (NF) training on executive function by comparing the results of neuropsychological tests of the trained children at pre- and post-training. Methods : Fifteen children with ADHD, aged 6 to 14 years, participated in the study. The NF treatment consisted of slow cortical potential (SCP) training and these sessions took place once a week. The ADHD children performed 20 sessions of NF training within 6 months. Pre-training and post-training assessments encompassed Continuous Performance Test (CPT), Stroop Test, Children's Color Trails Test I&II (CCTT) and Wisconsin Card Sorting Test (WCST). Results : Patients receiving NF training showed significant improvement in visual commission error and standard deviation of auditory response time on CPT ; and total errors on WCST. But there was no significant improvement in the Stroop test and CCTT. Conclusion : SCP training using NF improves the self-regulatory capacities and impulsivity in ADHD patient, especially impulsivity in visual stimulation tasks. This study showed evidence of clinical efficacy of NF on executive function in ADHD.

• 자원환경지질
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• 제41권5호
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• pp.617-624
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• 2008

카스피해에 인접한 아제르바이잔은 200여 년 전부터 석유개발을 시작하여 20세기 초에는 세계 석유의 50%를 생산하는 석유자원의 부국이 되었으며 소련 연방에서 분리 독립한 1991년 이후 카스피해 해상광구에 대하여 우리나라를 포함한 외국기업투자가 많이 이루어지고 있는 나라이다. 아제르바이잔 하류부문 석유산업은 상류부문에 비하여 낙후되어 있으나, 아제르바이잔에서 시작되는 BTC, SCP, NERP 및 WREP와 같은 파이프라인은 카스피해 석유 및 가스를 서방세계에 전달하는 중요한 역할을 하고 있다. 아제르바이잔 육상광구는 생산활동이 상당부문 이루어진 성숙유전들이다. 최근 유가의 급등으로 인하여 경제성이 높아진 해상 심해 광구는 탐사의 성공 잠재성은 있으나 위험부담율이 커서 신중한 투자가 필요하다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권4호
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• pp.137-143
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• 2021

Objectives: Despite the growing concern regarding the adverse effects related to problematic smartphone use (PSU), little is known about underlying morphologic changes in the brain. The brainstem is a deep brain structure that consists of several important nuclei associated with emotions, sensations, and motor functions. In this study, we sought to examine the difference in the volume of brainstem substructures among adolescents with and without PSU. Methods: A total of 87 Korean adolescents participated in this study. The PSU group (n=20, age=16.2±1.1, female:male=12:8) was designated if participants reported a total Smartphone Addiction Proneness Scale (SAPS) score of ≥42, whereas the remaining participants were assigned to the control group (n=67, age=15.3±1.7, female:male=19:48). High-resolution T1 magnetic resonance imaging was performed, and the volume of each of the four brainstem substructures [midbrain, pons, medulla, and superior cerebellar peduncle (SCP)] was measured. Analysis of covariance was conducted to reveal group differences after adjusting for effects of age, gender, whole brainstem volume, depressive symptoms, and impulsivity. Results: The PSU group showed a significantly smaller volume of the SCP than the control group (F=8.273, p=0.005). The volume of the SCP and the SAPS score were negatively correlated (Pearson's r=-0.218, p=0.047). Conclusion: The present study is the first to reveal an altered volume of the brainstem substructure among adolescents with PSU. This finding suggests that the altered white matter structure in the brainstem could be one of the neurobiological mechanisms underlying behavioral changes in PSU.

• 한국지반공학회논문집
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• 제20권9호
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• pp.17-23
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• 2004

굴양식장에서 폐기물로 처리되는 굴패각을 지반재료로 이용하기 위해서 굴패각-모래 혼합토의 강도 및 변형 특성에 대해 조사하였다. 타설된 모래다짐말뚝 재료의 강도는 표준관입시험(SPT)에 의해 현장에서 타설된 모래다짐말뚝 강도를 확인하는 것으로 되어있다. 그러나 모래는 표준관입시험에서 얻어진 N값과 내부마찰각의 관계에 대해 상당히 밝혀져 있으나, 굴패각-모래 혼합토에 대해서는 N값과 내부마찰각의 관계가 연구되어 있지 않다. 본 연구논문에서는 단위체적중량이 다양한 굴패각-모래 혼합토를 대형 모형토조에서 표준관입시험 및 대형 직접전단시험을 수행하여 N값, 단위체적중량, 내부마찰각의 상호 상관성을 제시하였다. 이러한 연구결과는 현장에서 표준관입시험을 통한 굴패각-모래 혼합토의 강도 평가가 가능하게 했으며 구속압축시험을 통하여 체적압축계수를 산정하고 혼합토의 예상침하량을 계산할 수 있게 하였다.