• Title/Summary/Keyword: SCH

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The Significance of Interleukin-6 in $Henoch-Sch\"{o}nlein$ Purpura Nephritis in Children ($Henoch-Sch\"{o}nlein$ Purpura 신염에서 Interleukin-6의 의의)

  • Lee Jae-Seung;Kwon Min-Joong
    • Childhood Kidney Diseases
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    • v.1 no.2
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    • pp.130-135
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    • 1997
  • Purpose : Interleukin-6(IL-6), a multifunctional cytokine, has been found to have growth and differentiation activities on a wide variety of tissues and cells, including mesangial cells. It has been known that IL-6 is an autocrine growth factor for the proliferation of mesangial cells. Several studies have been performed for revealing the clinical significance of IL-6 in mesangial proliferative glomerulonephritis. Methods : The author measured serum and urinary IL-6 in 30 patients with $Henoch-Sch\"{o}nlein$ purpura (HSP), 18 patients with HSP nephritis, and 10 normal children as a control group. Results : The serum level of IL-6 was increased significantly in the patients with HSP and HSP nephritis compared to normal control. The level of urinary IL-6 was increased significantly in the patients with HSP nephritis compared to both HSP and normal control groups. The level of urinary IL-6 was not correlated with the level of serum. Conclusion : IL-6 was correlated with the amount of proteinuria. These data suggest that IL-6 may be involved in the pathological proliferation of mesangial cell in HSP nephritis.

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Characterization of Laccase Purified from Korean Pycnoporus cinnabarinus SCH-3 (한국산 주걱송편버섯(Pycnoporus cinnabarinus) SCH-3로부터 정제 된 Laccase의 특성)

  • Park, Eun-Hye;Yoon, Kyung-Ha
    • The Korean Journal of Mycology
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    • v.31 no.2
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    • pp.59-66
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    • 2003
  • Laccase produced by Pycnoporus cinnabarinus SCH-3 isolated from Korea was partially purified using ultrafiltration, anion exchange chromatography and affinity chromatography, The laccase was produced as the predominant extracellular phenoloxidase during primary metabolism. Neither lignin peroxidase nor manganese-dependent peroxidase were detected in the culture fluid. In order to examine the effect of inducers in laccase production, 2,5-xylidine was added in the culture of Pycnoporus cinnabarinus SCH-3. Addition of 2,5-xylidine enhanced 25-fold laccase production. Purified laccase was a single polypeptide having a molecular mass of approximately 66 kDa, as determined by SDS-polyacrylamide gel electrophoresis, and carbohydrate content of 9%. $K_{m}\;and\;V_{max}$ values for laccase with ABTS [2,2-azinobis (3-ethylbenzthiazoline 6-sulfonic acid)] as a substrate (Lineweaver-Burk plot) was determined to be $44.4{\mu}M\;and\;56.0{\mu}mole$, respectively. The optimal pH for laccase activity was found to be 3.0. The enzyme was very stable for 1 hour at $60{\circ}C$. Half-life ($t_{1/2}$) of the enzyme was about 10 min at $80{\circ}C$. Spectroscopic analysis of purified enzyme indicated that the enzyme was typical of copper-containing protein. Substrate specificity and inhibitor studies for laccase also indicated to be a typical fungal laccase. The N-terminal amino acid sequence of the P. cinnabarinus SCH-3 laccase showed 94% of homology to the N-terminal sequences of laccases from P. cinnabarinus PB and P. coccineus.

Three Species of Gelechiidae New to Korea (Lepidoptera, Gelechioidea) (한국산 뿔나방과(나비목: 뿔나방상과)의 3 미기록종)

  • Park, Kyu-Tek;Lee, Bong-Woo;Cho, Soowon
    • Korean journal of applied entomology
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    • v.52 no.4
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    • pp.305-309
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    • 2013
  • Three species of Gelechiidae, Gnorimoschema streliciellum (Herrich-Sch$\ddot{a}$ffer, 1854), Syncopacma wormiella (Wolff, 1958), and Mesophleps acutunca Li and Sattler, 2012 are reported for the first time from Korea. Specific diagnoses and re-descriptions are provided as necessary, with adult and male genitalia images.

CELL SEARCH AND PERFORMANCE ANALYSIS OF W-CDMA SYSTEM IN REALISTIC MULTIPATH CHANNEL ENVIRONMENTS (광대역 다중경로 채널환경에서 W-CDMA 시스템의 셀 탐색과 성능분석)

  • 박대식;김병학;우연식;김철성
    • Proceedings of the IEEK Conference
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    • 2001.09a
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    • pp.591-594
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    • 2001
  • In the W-CDMA system, cell search is one of the imporant functions of the mobile station searching for a cell and achieving spreading code and time synchronization to its downlink scrembling code. For the methods of cell search to optimize codes, three stages are considered: 1) slot synchronization, 2) frame synchronization, and 3) scrambling code identification. Channels for cell search are Primary Synchronization Channel (P-SCH), Secondary Synchronization Channel(S-SCH), and Common Pilot Channel (CPICH). In this paper, cell search is analyzed based on simulation. Rake receiver provides improvement of Performance as an increase of bandwidth because there are more available multipaths. In this paper, the performance of W-CDMA system employing RAKE receiver is evaluated by computer simulation over the types of ITU_R wideband channel model and spreading rate. The result shows that the performance of CDMA adapting RAKE receiver is improved by the increase of multipath components in equal level of the received power.

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Machining Characteristics in Micro Electrochemical Drilling and Simulation (미세 전해 구멍 가공에서의 가공 특성과 시뮬레이션)

  • Kim B.H.;Lee Y.S.;Choi D.K.;Chu C.N.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1202-1205
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    • 2005
  • Micro hole is one of basic elements for micro device or micro parts. By micro ECM, micro holes less than $50\mu{m}$ in diameter can be machined easily. Machining characteristics of micro ECM were investigated according to machining conditions such as electrolyte concentration and pulse conditions. From the investigation, optimal machining conditions were suggested for micro ECM of stainless steel. For the micro machining with high resolution, the change of machining gap should be predicted. By using electrochemical principle equations, the change of machining gap was simulated.

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