• Title/Summary/Keyword: SBL

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Immune-Enhancing Activity of Staphylea bumalda Leave (고추나무 잎의 면역증진 활성)

  • Jin Boo Jeong
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.08a
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    • pp.86-86
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    • 2020
  • The leaves of Staphylea bumalda (S. bumalda) as a deciduous tree distributed in Korea, China and Japan are used to treat respiratory diseases or inflammation. However, there is no scientific research on the immune-enhancing activity of S. bumalda leaves. Thus, in this study, we investigated the effect of water extracts from S. bumalda leaves (SBL) on the macrophage activity using mouse macrophage cells, RAW264.7. SBL increased production of immunomodulators such as NO, iNOS, IL-1β, IL-6, TNF-α and MCP-1 in RAW264.7 cells and activated phagocytic activity of RAW264.7 cells. Inhibition of TLR2 and TLR4 blocked SBL-mediated production of immunomodulators in RAW264.7 cells. In addition, SBL-mediated production of immunomodulators was attenuated by JNK inhibition in RAW264.7 cells. SBL increased JNK phosphorylation, while Inhibition of TLR2 and TLR4 blocked SBL-mediated JNK phosphorylation in RAW264.7 cells. These results are thought to be evidence that SBL activates JNK through stimulation of TLR2 and TLR4 in macrophage to induce the production of immunomodulators. In LPS-stimulated RAW264.7 cells, SBL inhibited over-production of immunomodulators. Summarizing the results, SBL showed immunostimulatory activity under normal conditions and immunosuppressive activity under LPS-induced excessive immune response conditions.

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Scenario-based Learning: Experiences from Construction Management Courses

  • Lim, Benson Teck-Heng;Oo, Bee Lan
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.583-587
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    • 2015
  • Scenario-based learning (SBL) has been used in a variety of training situations across different disciplines. Despite its seemly widespread use in construction management discipline, very few attempts have been made to explore its effectiveness and the respective students' learning experience. Using a survey research design, this study aims to investigate students' perceptions on SBL approach in construction management courses. The specific objectives are: (i) to identify the characteristics of a favourable SBL environment, and (ii) to explore the students' learning experience and effectiveness of the SBL approach. The results show that the four characteristics of a favourable SBL environment are: effective team formulation, constant engagement with lecturer, working in a group, and incorporation of motivational incentive for participation. The students really appreciated the opportunities to apply concepts learnt in the lectures in their SBL group work. Also, they perceived that the SBL approach is effective in developing their reflective and critical thinking skills, analytic and problem-solving skills and their ability to work as a team. These findings should facilitate more critical approaches to similar form of teaching methods.

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Cell Signal Distribution Characteristics For High Density FeRAM

  • Kang, Hee-Bok;Park, Young-Jin;Lee, Jae-Jin;Ahn, Jin-Hong;Sung, Man-Young;Sung, Young-Kwon
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.4 no.3
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    • pp.222-227
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    • 2004
  • The sub-bitline (SBL) sensing voltage of a cell and total cell array can be measured by the method of SBL voltage evaluation method. The MOSAID tester can collect all SBL signals. The hierarchical bitline of unit cell array block is composed of the cell array of 2k rows and 128 columns, which is divided into 32 cell array sections. The unit cell array section is composed of the cell array of 64 rows and 128 columns. The average sensing voltage with 2Pr value of $5{\mu}C/cm^2$ and SBL capacitance of 40fF is about 700mV at 3.0V operation voltage. That is high compensation method for capacitor size degradation effect. Thus allowed minimum 2Pr value for high density Ferroelectric RAM (FeRAM) can move down to about less than $5{\mu}C/cm^2$.

Sea Buckthorn (Hippophae rhamnoides L.) Leaf Extracts Protect Neuronal PC-12 Cells from Oxidative Stress

  • Cho, Chi Heung;Jang, Holim;Lee, Migi;Kang, Hee;Heo, Ho Jin;Kim, Dae-Ok
    • Journal of Microbiology and Biotechnology
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    • v.27 no.7
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    • pp.1257-1265
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    • 2017
  • The present study was carried out to investigate the antioxidative and neuroprotective effects of sea buckthorn (Hippophae rhamnoides L.) leaves (SBL) harvested at different times. Reversed-phase high-performance liquid chromatography analysis revealed five major phenolic compounds: ellagic acid, gallic acid, isorhamnetin, kaempferol, and quercetin. SBL harvested in August had the highest total phenolic and flavonoid contents and antioxidant capacity. Treatment of neuronal PC-12 cells with the ethyl acetate fraction of SBL harvested in August increased their viability and membrane integrity and reduced intracellular oxidative stress in a dose-dependent manner. The relative populations of both early and late apoptotic PC-12 cells were decreased by treatment with the SBL ethyl acetate fraction, based on flow cytometry analysis using annexin V-FITC/PI staining. These findings suggest that SBL can serve as a good source of antioxidants and medicinal agents that attenuate oxidative stress.

Hybrid Genetic Algorithm for Facility Layout Problems with Unequal Area and Fixed Shapes (고정된 형태와 크기가 다른 설비의 배치를 위한 혼합 유전자 알고리듬)

  • Lee, Moon-Hwan;Lee, Young-Hae;Jeong, Joo-Gi
    • Journal of Korean Institute of Industrial Engineers
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    • v.27 no.1
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    • pp.54-60
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    • 2001
  • In this paper, a shape-based block layout (SBL) approach is presented to solve the facility layout problem with unequal-area and fixed shapes. The SBL approach employs hybrid genetic algorithm (Hybrid-GA) to find a good solution and the concept of bay structure is used. In the typical facility layout problem with unequal area and fixed shapes, the given geometric constraints of unequal-area and fixed shapes are mostly approximated to original shape by aspect ratio. Thus, the layout results require extensive manual revision to create practical layouts and it produces irregular building shapes and too much unusable spaces. Experimental results show that a SBL model is able to produce better solution and to create more practical layouts than those of existing approaches.

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Guideline for Preparation of Manuscript for Proceedings (신분당선 CBTC구간과 분당선 ATC구간의 절체운전에 대한 고찰)

  • Jang, Kwang-Dong;Cha, Ki-Ju;Kang, Deok-Won;Lee, Jong-Seong
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.2017-2022
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    • 2009
  • Sinbundang Line(SBL) Train moves the transition zone where is located between Jeongja station and Migeum station switched over from Communication Based Train Control (CBTC) system area to Automatic Train Control (ATC) system area and viceversa. The SBL train to move the between SBL and Bundang Line is needed to install the Specific Transmission Module (STM) on SBL Line for interface with Bundang Line; STM receives from speed code from Bundang Line. So we suggested the method to ensure mutual compatibility and reliability for train operation on each other signaling system.

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Computationally efficient variational Bayesian method for PAPR reduction in multiuser MIMO-OFDM systems

  • Singh, Davinder;Sarin, Rakesh Kumar
    • ETRI Journal
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    • v.41 no.3
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    • pp.298-307
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    • 2019
  • This paper investigates the use of the inverse-free sparse Bayesian learning (SBL) approach for peak-to-average power ratio (PAPR) reduction in orthogonal frequency-division multiplexing (OFDM)-based multiuser massive multiple-input multiple-output (MIMO) systems. The Bayesian inference method employs a truncated Gaussian mixture prior for the sought-after low-PAPR signal. To learn the prior signal, associated hyperparameters and underlying statistical parameters, we use the variational expectation-maximization (EM) iterative algorithm. The matrix inversion involved in the expectation step (E-step) is averted by invoking a relaxed evidence lower bound (relaxed-ELBO). The resulting inverse-free SBL algorithm has a much lower complexity than the standard SBL algorithm. Numerical experiments confirm the substantial improvement over existing methods in terms of PAPR reduction for different MIMO configurations.

Efficient Quantizer Design Algorithm for Sequence-Based Localization (SBL) Systems (시퀀스 기반 위치추정 시스템을 위한 효율적인 양자기 설계 알고리즘)

  • Park, Hyun Hong;Kim, Yoon Hak
    • Journal of IKEEE
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    • v.24 no.1
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    • pp.40-45
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    • 2020
  • In this paper, we consider an efficient design of quantizers at sensor nodes for sequence-based localization (SBL) systems which recently show a competitive performance for in-door positioning, Since SBL systems locate targets by partitioning the sensor field into subregions, each with an unique sequence number, we use the distance samples between sensors and the sequences for quantizer design in order to propose a low weight design process. Furthermore, we present a new cost function devised to assign the number of samples and the number of unique sequences uniformly into each of quantization partitions and design quantizers by searching the quantization partitions and codewords that minimize the cost function. We finally conduct experiments to demonstrate that the proposed algorithm offers an outstanding localization performance over typical designs while maintaining a substantial reduction of design complexity.

Illegal Issuing Practices of Switched Bill of Lading and Precautions against their Potential Risks (스위치선하증권의 불법적 발행 관행에 따른 위험과 그 대책)

  • Park, Sae-Woon
    • International Commerce and Information Review
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    • v.14 no.2
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    • pp.389-409
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    • 2012
  • The Switched Bill of Lading(SBL) has been in frequent use in recent years as intermediary trade increases with the growing number of companies' overseas subsidiaries. Its frequent use, though, has brought about disputes regarding its illegal issue. Although there are several legal cases regarding this, studies on this issue are hard to find. Therefore, this study tries to provide countermeasures and precautions against unlawful issues of SBL through examining the legal cases resulting from illegal issuing practices of SBL. When the Switched Bill of Lading is issued, the shipper, consignee, port of loading and unloading, and shipping date of the original bill of lading are usually changed. Statements which may put the shipper at a disadvantageous position may also be deleted and/or the bill of lading may be either divided or integrated when it is issued. However, if the carrier issues the SBL 1)without withdrawing original BL, 2)indicating the shipping date, port of loading and port of discharge falsely, or 3)deleting the statements which may give him disadvantages, it may be regarded as an illegal issue. These unlawful issues of SBL may pose a huge threat to the shipper, banks and the parties relating to the trade. That is, the shipper may take a substantial loss when the goods can be delivered to a third party by SBL without his collecting the proceeds. The issuing bank and the negotiating bank may also have their security rights to the goods hampered by the illegal and improper issue of SBL. In most cases, the carrier has no choice but to issue the SBL without collecting the original BL for fear of hurting the relationship with the intermediary traders. This practice of issuing more than two sets of BL may pose a potential risk to the carrier.

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Experimental investigation on small scale siphon breaker (소규모 사이펀 차단기에 대한 실험적 연구)

  • Ji, Dae-Yun;Kim, Sung hoon;Lee, Kwon-Yeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.5
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    • pp.1-8
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    • 2018
  • In this study, a small-scale siphon breaker experimental facility was designed to examine the validity of the Siphon Breaker Simulation Program (SBSP). To design the experimental facility, the simulation results of the C factor, Chisholm B coefficient, and Undershooting Height (UH) were obtained by SBSP. The major parts of the experimental facility were the upper tank, lower tank, downcomer, and Siphon Breaker Line (SBL). The area of the Upper tank was $0.09-m^2$ with a height of 0.65-m. The height of the downcomer was 1.6-m. Pressure transmitters and an electronic scale were used to obtain the experimental results. The experimental variables were the sizes of Loss of Coolant Accident (LOCA) and SBL. The experimental results were analyzed by UH. The SBSP well predicted the UH with an error of 2.5%. Overall, it is possible to design siphon breakers with various scales using SBSP.