• Title/Summary/Keyword: SB Factor

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Synergic Anti-Pruritic and Anti-Inflammatory Effects of Scutellariae Radix plus Flos Loncerae Extracts in Rat Peritoneal Mast Cell and Chemical Antigen-Induced Mice (렛트 복강 비만세포와 화학항원 유도 알레르기 마우스에서 황금과 금은화 추출물의 항가려움 및 항염증 상승효과)

  • Mok, Ji Ye;Jeon, In Hwa;Kim, Hyeon Soo;Shin, Jun Ho;Park, Yong Gyoun;Jang, Seon Il
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.1
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    • pp.83-91
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    • 2013
  • Pruritus is a unpleasant symptom in the skin that provokes the act of or desire to scratch. Mast cells are important effector cells in allergic reactions such as pruritus and inflammation. The purpose of this study was undertaken to investigate the synergic anti-pruritic and anti-inflammatory effects of Scutellariae Radix (SB) plus Flos Loncerae (FL) extracts in rat peritoneal mast cells (RPMCs), pruritogen-induced scratching mice and 2,4-dinitrofluorobenzene (DNFB)-induced allergic mice. We investigated the effect of SB, FL and SB plus FL extracts on the production of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$, and histamine in RPMCs, on the scratching behavior in ICR mice, and skin clinical serverity and inflammatory mediators in DNFB-induced allergic hairless mice. RPMCs stimulated with PMA plus A23187 or compound 48/80 significantly increased TNF-${\alpha}$, IL-$1{\beta}$ or histamine production compared with media control. However, TNF-${\alpha}$ IL-$1{\beta}$ or histamine levels increased by PMA plus A23187 or compound 48/80 treatment were significantly inhibited by SB, FL in a dose-dependent manner. Especially, SB plus FL pretreatment had a synergic inhibitory effects on stimulator-induced cytokines (TNF-${\alpha}$ and IL-$1{\beta}$) and histamine production. Moreover, SB plus FL administration had a synergic inhibitory effects on the scratching behavior induced by pruritogen (compound 48/80, histamine, serotonin, substance P) in ICR mice. Furthermore, SB plus FL administration had a synergic inhibitory effects on skin damage, inflammatory mediators, leukocyte and mast cell infiltration induced by DNFB in hairless mice. These results suggest that SB plus FL administration has a potential use as a medicinal plant for treatment against itching and inflammation-related skin disease.

Isolation, Identification, and Fermentation Characteristics of Bacillus sp. with High Protease Activity from Traditional Cheonggukjang (전통 청국장으로부터 protease 분비능이 우수한 Bacillus sp. 균주의 분리 동정 및 발효 특성)

  • Ahn, Yong-Sun;Kim, Yong-Suk;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.38 no.1
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    • pp.82-87
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    • 2006
  • Twenty one strains strongly producing protease were isolated from Korean traditional Cheonggukjang. Eight strains selected by sensory evaluation on Cheonggukjang prepared with isolated strains were identified with based on biochemical properties a and 16S rDNA sequencing. Identified strains were Bacillus subtilis MB4, and Bacillus amyloliquefaciens A1, A2, B1, MC1, SB2, SC1, and SD1. Protease activities, important strain selection factor, were higher in Cheongjukjang prepared with B. subtilis MB4 (179.6 Unit) and B. amyloliquefaciens SB2 (201.9 Unit) than commercial traditional Cheonggukjang (97.9 Unit). Sensory evaluation revealed Cheonggukjang prepared with B. subtilis MB4 had flavor very similar to commercial traditional Cheonggukjang. Cheonggukjang prepared with B. suhtilis MB4 (0.0006 Pa s) and commercial traditional Cheonggukjang (0.0002 Pa s) revealed lower viscosities than those of Cheonggukjang prepared with B. amyloliquefaciens SB2, MC1, B1, A1, SD1, A2, and SC1 (0.006 to 0.008 Pa s at 1001/s. Results show Cheonggukjang could be prepared using single strain of B. subtilis MB4, maintaining high protease activity and very similar sensory and viscosity qualities with those of commercial traditional Cheonggukjang.

The Analysis of Mechanism on Color Scheme and Emotional Affectivity Preferences according to Wood Material Finishing in the Cafe Images (카페 이미지에서 목재 마감재에 따른 색채배색과 감성 선호도 분석 메커니즘)

  • Choi, Jin-Kyung;Kim, Ju-Yeon
    • Journal of Korean Living Environment System
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    • v.24 no.5
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    • pp.654-664
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    • 2017
  • The use of environmentally friendly finishing materials allows us to create a space where we can feel nature and to have stability and peace in the city center. In this paper, we examined the sensitivity of people to the three café spaces where wooden finishing materials are used in the space elements that change according to people's demands for environmentally friendly space due to pollution of living environment. First, we examined the wood and finishing materials and emotional vocabulary through literature review and previous research. Second, the values of L *, a *, b* and sR, sG and sB values were extracted by using a line spectrophotometer (Ci6X). Third, we conducted a 7 - point scale questionnaire based on the extracted 13 pairs of emotional vocabulary. Using SPSS 21, frequency analysis by descriptive statistics, crossover analysis by visiting purpose and intention, and emotional lexical factor analysis were performed. Through the study, the following points were found. First, CB (The Coffee Bean), SB (Starbucks) and HS (Hollys Coffee) showed differences in CB (65%), SB (40%) and HS (37%) in the spatial analysis. Second, CB gave color similar to the color of wall and furniture wood, but HS changed the color or brightness of wood finishing color of furniture. HS or SB showed favorable use of wood color scheme. Third, SB (26.3%) and HS (19.7%) were selected by taste. Fourth, there were differences in the items of CB, 'local-exotic' and SB 'dark-bright' in the factor value. The use of wood finishing materials differed in the atmosphere evaluation depending on the spatial factors and the color of the furniture. However, in this study, there are many factors that are insufficient in the accuracy of the ratio of the applied wood finishing material to the space element and the amount of the survey. If we further study the evaluation of emotional image according to the ratio of wood finishing materials, we think that it is necessary to study now that interest in environmentally friendly is increasing.

Strength Estimation of Stylene-Butadien Latex Modified Concrete by Factorial Experimental Design (요인 실험분석에 의한 SB 라텍스 개질 콘크리트의 강도예측)

  • Yun, Kyong-Ku;Lee, Joo-Hyung;Hong, Chang-Woo
    • Journal of Industrial Technology
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    • v.21 no.B
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    • pp.307-315
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    • 2001
  • The purpose of this study was to provide the evaluation and prediction of strengths of SB latex modified concrete(LMC) using a statistical method and factorial experimental design method. The main experimental variables were as follows ; W/C ( 4 levels ; 31, 33, 35, 42%), S/a( 2 levels ; 55, 58%) and L/C(2 levels ; 5, 15%). The compressive strength and flexural strength of LMC were selected as a factor of response. The statistical method was carried out to analyze the results, together with factorial experimental design method and response surface method. The analysis showed that if L/C had been 15%, W/C appeared to be around 33% to achieve the design strength of $350kgf/cm^2$. In this case, the flexural strength and the slump came to around $68kgf/cm^2$ and 18cm, respectively. Eventhough the L/C varied, the design strength and W/C could be predictable together with slump value and flexural strength. As a result of series of experiments in this study, W/C and L/C were proved to be the main factors influencing on the compressive and flexural strength of LMC. Both of strength and slump values could be predictable from the mixing proportion of LMC.

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Microstructure and Piezoelectric Properties of Low Temperature Sintering (Na,K,Li)(Nb,Sb,Ta)O3 Ceramics (저온소결 (Na,K,Li)(Nb,Sb,Ta)O3계 세라믹스의 미세구조 및 압전특성)

  • Lee, Kab-Soo;Yoo, Ju-Hyun;Lee, Jie-Young
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.29 no.4
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    • pp.205-209
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    • 2016
  • In this paper, piezoelectric ceramics with the composition of $(Na_{0.525}K_{0.4425}Li_{0.0375})(Nb_{0.8975}Sb_{0.065}Ta_{0.0375})O_3+0.3wt%\;CoO+x\;CuO$ ($0.005{\leq}x{\leq}0.025$) (abbreviated to NKL-NST) were fabricated for ultrasonic sensor application. The effects of CuO addition and sintering on the microstructure and the piezoelectric properties of the NKL-NST ceramics were systematically studied. Excellent piezoelectric properties such as electromchanical coupling $factor(k_p)=0.415$, piezoelectric constant $(d_{33})=166pC/N$ and piezoelectric figure of merit $d_{{33}*}g_{33}=5.47pm^2/N$ were obtained from the 2.5 mol% CuO doped NKL-NST+0.3 wt%CoO ceramics sintered at $1,000^{\circ}C$ for 3 h.

Studies on the Multi-layered Coated Paper(II) -Effects of Binder in Pre-coated Layer on Properties of Top-coated Layer- (다층 도공지에 관한 연구(II) - 프리코팅층의 바인더가 탑층에 미치는 영향 -)

  • Choi, Ki-Soon;Shin, Woo-Seul;Kim, Sun-Kyung;Cho, Byoung-Uk;Lee, Yong-Kyu
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2011.10a
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    • pp.443-453
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    • 2011
  • This study was carried out in order to elucidate effects of types of binder used in pre-coated layer on optical properties and printability of top-coated layer. Coated papers with four different types of SB latex were prepared. Tg, particle size and gel contents of latices were of different. Optical properties and printability of coated paper including print mottle were evaluated. It was confirmed that properties of pre-coated layer distinctively affected final properties of top-coated layer. Tg was found to be the most influencing factor on the print mottle of coated paper: the SB latex with lower Tg and higher particle size resulted in a superior print mottle. These results indicate that final printability and properties of top-coated layer can be controlled by adjusting pre-coated layer.

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Effect of Sintering Temperature on the Dielectric and Piezoelectric Properties of (Na,K,Li)(Nb,Sb,Ta)O3 Ceramics (소성 온도가 (Na,K,Li)(Nb,Sb,Ta)O3 세라믹스의 유전 및 압전 특성에 미치는 영향)

  • Kim, You-Seok;Yoo, Ju-Hyun;Hong, Jae-Il;Lee, Jie-Young
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.26 no.11
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    • pp.806-809
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    • 2013
  • In this study, $(Na_{0.525}K_{0.443}Li_{0.037})(Nb_{0.883}Sb_{0.08}Ta_{0.037})O_3+0.10\;wt%Bi_2O_3+0.35\;wt%B_2O_3$ ceramics were prepared by conventional soild-state sintering process. The specimens were sintered at temperature range from $1,060^{\circ}C$ to $1,100^{\circ}C$. XRD (X-ray diffractron), SEM (scanning electron microscope) were used to analyze the crystal structure and microstructural sproperties of specimens. And also, $T_{O-T}$, TC were observed by the mesurement of temperature dependence of dielectric constant. Excellect physical properties of the piezoelectric constant $d_{33}$= 170 pC/N, electromechanical coupling factor kp= 0.312, Tc= $315^{\circ}C$ were obtained, respectively, from the specimen sintered at $1,080^{\circ}C$.

Effect of Sintering Time on the Piezoelectric Properties of (Na,K,Li)(Nb,Sb,Ta)O3 Ceramics ((Na,K,Li)(Nb,Sb,Ta)O3계 세라믹스의 소성시간이 압전특성에 미치는 영향)

  • Kim, Seung-Won;Yoo, Ju-Hyun
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.30 no.4
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    • pp.218-222
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    • 2017
  • In this paper, in order to develop excellent composition ceramics for a piezoelectric energy- harvesting device, we synthesized $0.99(Na_{0.52}\;K_{0.443}\;Li_{0.037})(Nb_{0.883}\;Sb_{0.08}\;Ta_{0.037})O_3$ + $0.01(Sr_{0.95}Ca_{0.05})TiO_3$ + $0.3\;wt%\;Bi_2O_3\;+\;0.3\;wt%\;Fe_2O_3\;+\;0.3\;wt%\;CuO$ (abbreviated as NKN-SCT) ceramics with different sintering times, using the ordinary solid-state reaction method. The effect of sintering time on the microstructure and piezoelectric properties was investigated. The ceramics with the sintering time of 7 h have the optimum values of the piezoelectric constant ($d_{33}$), piezoelectric voltage constant ($g_{33}$), planar piezoelectric coupling coefficient (kp), mechanical quality factor (Qm), and dielectric constant (${\varepsilon}r$): $d_{33}=314[pC/N]$, $g_{33}=20.07[10^{-3}mV/N]$, kp = 0.442, Qm = 93, ${\varepsilon}r=1,768$, all being suitable for a piezoelectric energy-harvesting device.

Piezoelectric and Dielectric Properties of Low Temperature Sintering (Na,K,Li)(Nb,Sb,Ta)O3 Ceramics Doped with CuO (CuO 첨가된 저온소결 (Na,K,Li)(Nb,Sb,Ta)O3계 세라믹스의 압전 및 유전 특성)

  • Lee, Gwang-Min;Yoo, Ju-Hyun;Lee, Jie-Young
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.28 no.4
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    • pp.229-233
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    • 2015
  • In this paper, in order to develop outstanding Pb-free piezoelectric composition ceramics, the $(Na_{0.525}K_{0.443}Li_{0.037})(Nb_{0.883}Sb_{0.08}Ta_{0.037})O_3+0.3wt%Bi_2O_3+0.4wt%Fe_2O_3+xwt%CuO$ (x= 0~0.8 wt%)(abbreviated as NKL-NST) lead-free piezoelectric ceramics have been synthesized using the ordinary solid state reaction method. The effects of CuO-doping on the structure and electrical properties of the NKL-NST ceramics were systematically studied. The results show that the ceramics exhibit a pure perovskite structure with orthorhombic phase at room temperature, and secondary phase was found in the ceramics. The 0.4 wt%CuO added ceramics sintered at $950^{\circ}C$ showed the optimum properties of piezoelectric constant($d_{33}$), planar piezoelectric coupling coefficient(kp) and mechanical quality factor(Qm) : $d_{33}=213$[pC/N], kp= 0.43, Qm= 423,respectively.

Dielectric and Piezoelectric Properties of (Na,K,Li)(Nb,Sb,Ta)O3 Ceramics as a Function of CuO Addition (CuO 첨가에 따른 (Na,K,Li)(Nb,Sb,Ta)O3 세라믹스의 유전 및 압전 특성)

  • Lee, KabSoo;Kim, YouSeok;Yoo, JuHyun;Mah, Sukbum
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.27 no.10
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    • pp.630-634
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    • 2014
  • $(Na_{0.525}K_{0.4425}Li_{0.0375})(Nb_{0.9975}Sb_{0.065}Ta_{0.0375})O_3+0.3 wt%CoO$ ceramics were fabricated as a function of CuO addition by traditional solid state sintering process in order to develop excellent lead-free piezoelectric ceramics composition. The addition of CuO in the LNKNTS composition ceramics can effectively enhance the densification of the ceramics, resulting in the oxygen vacancies as hardening effect. The excellent piezoelectric properties of electromechanical coupling factor($k{\small}_P$) of 0.378, piezoelectric constant($d_{33}$) of 152 pC/N were obtained from the 1.0 mol% CuO doped LNKNTS ceramics sintered at $1,020^{\circ}C$ for 3 h.