• Title/Summary/Keyword: SAG3

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Mechanical Behavior of Cable Net Structures Considering Sag Ratio (새그 비를 고려한 케이블 네트 구조물의 역학적 거동)

  • Park, Kang-Geun;Lee, Dong-Woo
    • Journal of Korean Association for Spatial Structures
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    • v.16 no.3
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    • pp.47-58
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    • 2016
  • Cable network system is a flexible lightweight structure which curved cables can transmit only tensile forces. The weight of cable roof dramatically can reduce when the length becomes large. The cable network system is too flexible, most cable systems are stabilized by pretension forces. The tensile force of cable system is greatly influenced by the sag ratio and pretension forces. Determining initial sag ratio of cable roof system is essential in a design process of cable structures. Final sag ratio and pretension depends on initial installed sag and on proper handling during installation. The design shape of cable system has an affect on the sag and pretension, and must be determined using well-defined design philosophy. This paper is carried out the comparative data of the deflection and tensile forces on the geometric non-linear analysis of cable network systems according to sag ratio. The study of cable network system is provided to technical informations for the design of a large span cable roof, analytical results are compared with the results of other researchers. Structural nonlinear analysis of systems having cable elements is relatively complex than other rigid structural systems because displacements are large as a reason of flexibility, initial prestress is applied to cables in order to increase the rigidity, and then divergence of nonlinear analysis occurs rather frequently. Therefore, cable network systems do not exhibit a typical nonlinear behavior, iterative method that can handle geometric nonlinearities are necessary.

Small Molecule-Based Strategy Promotes Nucleus Pulposus Specific Differentiation of Adipose-Derived Mesenchymal Stem Cells

  • Hua, Jianming;Shen, Ning;Wang, Jingkai;Tao, Yiqing;Li, Fangcai;Chen, Qixin;Zhou, Xiaopeng
    • Molecules and Cells
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    • v.42 no.9
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    • pp.661-671
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    • 2019
  • Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising for regenerating degenerated intervertebral discs (IVDs), but the low efficiency of nucleus pulposus (NP)-specific differentiation limits their clinical applications. The Sonic hedgehog (Shh) signaling pathway is important in NP-specific differentiation of ADSCs, and Smoothened Agonist (SAG) is a highly specific and effective agonist of Shh signaling. In this study, we proposed a new differentiation strategy with the use of the small molecule SAG. The NP-specific differentiation and extracellular matrix (ECM) synthesis of ADSCs were measured in vitro, and the regenerative effects of SAG pretreated ADSCs in degenerated IVDs were verified in vivo. The results showed that the combination of SAG and transforming growth factor-${\beta}3$ ($TGF-{\beta}3$) is able to increase the ECM synthesis of ADSCs. In addition, the gene and protein expression levels of NP-specific markers were increased by treatment with SAG and $TGF-{\beta}3$. Furthermore, SAG pretreated ADSCs can also improve the disc height, water content, ECM content, and structure of degenerated IVDs in vivo. Our new differentiation scheme has high efficiency in inducing NP-specific differentiation of ADSCs and is promising for stem cell-based treatment of degenerated IVDs.

A Novel Detection Technique for Voltage Sag in Distribution Lines Using the Wavelet Transform

  • Ko, Young-Hun;Kim, Chul-Hwan;Ahn, Sang-Pil
    • KIEE International Transactions on Power Engineering
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    • v.3A no.3
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    • pp.130-138
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    • 2003
  • This paper presents a discrete wavelet transform approach for determining the beginning and end times of voltage sags. Firstly, investigations in the use of some typical mother wavelets, namely Daubechies, Symlets, Coiflets and Biorthogonal are carried out and the most appropriate mother wavelet is selected. The proposed technique is based on utilizing the maximum value of Dl (at scale 1) coefficients in multiresolution analysis (MRA) based on the discrete wavelet transform. The results are compared with other methods for determining voltage sag duration, such as the Root Mean Square (RMS) voltage and Short Time Fourier Transform (STFT) methods. It is shown that the voltage sag detection technique based on the wavelet transform is a satisfactory and reliable method for detecting voltage sags in power quality disturbance analysis.

Three Phase Voltage Sag and Harmonics Compensator based on the Direct Filtering Algorithm (직접 필터링 알고리즘 기반의 3상 전압sag 및 고조파 전류 보상 시스템)

  • Kim, Jung-Kun;Lim, Young-Cheol;Jung, Young-Gook
    • Proceedings of the KIEE Conference
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    • 2002.11d
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    • pp.218-220
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    • 2002
  • 본 연구에서는 정상상태에서 고조파 전류와 순시전압 강하에 대한 보상성능이 우수한 3상 전압 Sag 및 고조파 전류 보상 시스템을 제안하고 있다. 제안된 시스템의 보상 알고리즘으로는 구현하기 쉽고 간단한 직접 필터링 알고리즘이 사용되고 있으며 하이브리드 직렬형 능동전력필터에 적용하였다. 제안된 알고리즘은 전원전압이 순간적으로 왜형과 sag가 발생되더라도 비선형 부하에 인가되는 전압은 일정한 정현파로 제어 가능하며 동시에 전원전류의 고조파와 기본파 무효전류도 보상 가능하다. 정상상태와 과도상태에서 전력전자전용 시뮬레이터인 PSIM에 의해 제안된 이론의 타당성을 입증하였다.

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Method to Estimate Expected Sag Frequency Considering the Operating Condition of Power System (전력계통 운전조건을 고려한 순간전압강하 추계 방법)

  • Son, Jeongdae;Lee, Kyebyung;Park, Chang-Hyun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.65 no.3
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    • pp.382-387
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    • 2016
  • This paper deals with the assessment of voltage sags regarding the variation of system operating conditions. In general, voltage sag assessment is performed by assuming the constant operating condition throughout the year. However, the assumption can lead to assessment errors in case of considerable changes of system operation condition. This paper presents a method to estimate ESF(expected sag frequency) considering the operating conditions according to the changes of power demand throughout the year.

Cable sag-span ratio effect on the behavior of saddle membrane roofs under wind load

  • Hesham Zieneldin;Mohammed Heweity;Mohammed Abdelnabi;Ehab Hendy
    • Wind and Structures
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    • v.36 no.3
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    • pp.149-160
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    • 2023
  • Lightness and flexibility of membrane roofs make them very sensitive to any external load. One of the most important parameters that controls their behavior, especially under wind load is the sag/span ratio of edge cables. Based on the value of the pretension force in the edge cables and the horizontal projection of the actual area covered by the membrane, an optimized design range of cable sag/span ratios has been determined through carrying on several membrane form-finding analyses. Fully coupled fluid structure dynamic analyses of these membrane roofs are performed under wind load with several conditions using the CFD method. Through investigating the numerical results of these analyses, the behavior of membrane roofs with cables sag/span ratios selected from the previously determined optimized design range has been evaluated.

Voltage Sag and Swell Generator with Thyristor Controlled Reactor (TCR을 이용한 Voltage Sag와 Swell 발생장치에 대한 연구)

  • Park, T.B.;Kwon, G.H.;Chung, Y.H.;Lee, J.;Lim, G.Y.
    • Proceedings of the KIEE Conference
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    • 2002.07a
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    • pp.25-27
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    • 2002
  • This paper describes a new economical voltage sag and swell generator suitable to the evaluations of high power custom power devices such as DVR (Dynamic Voltage Restorer) and DSTATCOM (Distribution Static Compensator). This system was designed to generate the several power quality disturbances in MVA power ratings - voltage sag and swell, under voltage, over voltage and harmonic distortions. The basic idea for voltage sag and swell is to use the voltage drop across a reactor, while the voltage swell is to use the step-up transformer and the TCR(Thyristor Controlled Reactor). In this paper, two identical 3 phase TCRs and a step-up transformer with tap changer are used. Additional harmonic filters are added to reduce the voltage distortion when TCRs are operated. Simulation results are given for several cases of voltage sag and swell generations.

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Landscape Preference and Image Property according to Middle Span and Sag Ratio of the Suspension Bridge (현수교의 중앙경간과 새그비에 따른 경관선호도와 이미지특성 분석)

  • Jang, Young-Ju;Son, Seung-Neo;Kum, Ki-Jung;Oh, Heung-Un
    • International Journal of Highway Engineering
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    • v.13 no.1
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    • pp.1-11
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    • 2011
  • This study is aimed at suggesting a plan for creating a landscape environment by grasping a landscape preference according to the change of middle span and sag ratio which is a consideration factor when designing the suspension bridge representing long-span bridges and image property of the bridge while applying SD method to a relation between landscape preference and image factor, and a connection of design element with image factor. An analysis on landscape preference about the bridge landscape showed from what the longer the length of middle span, the extent of sag ratio of preference decreased, the longer the middle span low sag ratio was preferred and the higher the landscape preference became. In landscape preference and image factor, the attribute of sag ratio with high landscape preference was all positively correlated with "stability", "plasticity", and "aesthetic" but an influence of "plasticity" was insignificant. In the relation between design element and image factor, the factor of middle span and sag ratio was more related to the factor of "stability" and the lower the sag ratio and the longer the middle span, the higher the "stability" was rated. This result showed the image property of "plasticity" was insignificant among the one of preference in landscape and to highlight the one of "plasticity" a complementary experiment was done with a change in balance and symmetry elements not in proportional element of middle span and sag ratio. The result showed the image property of "plasticity" was more highlighted in the suspension bridge of 3-tower and different bilateral symmetry at sag, and when designing the landscape of suspension bridge later on, the elements of balance and symmetry as well as the proportional element should be considered and reflected in the design.

Tat-Fused Recombinant Human SAG Prevents Dopaminergic Neurodegeneration in a MPTP-Induced Parkinson's Disease Model

  • Sohn, Eun Jeong;Shin, Min Jea;Kim, Dae Won;Ahn, Eun Hee;Jo, Hyo Sang;Kim, Duk-Soo;Cho, Sung-Woo;Han, Kyu Hyung;Park, Jinseu;Eum, Won Sik;Hwang, Hyun Sook;Choi, Soo Young
    • Molecules and Cells
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    • v.37 no.3
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    • pp.226-233
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    • 2014
  • Excessive reactive oxygen species (ROS) generated from abnormal cellular process lead to various human diseases such as inflammation, ischemia, and Parkinson's disease (PD). Sensitive to apoptosis gene (SAG), a RING-FINGER protein, has anti-apoptotic activity and anti-oxidant activity. In this study, we investigate whether Tat-SAG, fused with a Tat domain, could protect SH-SY5Y neuroblastoma cells against 1-methyl-4-phenylpyridinium ($MPP^+$) and dopaminergic (DA) neurons in the substantia nigra (SN) against 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP) toxicity. Western blot and immunohistochemical analysis showed that, unlike SAG, Tat-SAG transduced efficiently into SH-SY5Y cells and into the brain, respectively. Tat-SAG remarkably suppressed ROS generation, DNA damage, and the progression of apoptosis, caused by $MPP^+$ in SH-SY5Y cells. Also, immunohistochemical data using a tyrosine hydroxylase antibody and cresyl violet staining demonstrated that Tat-SAG obviously protected DA neurons in the SN against MPTP toxicity in a PD mouse model. Tat-SAG-treated mice showed significant enhanced motor activities, compared to SAG- or Tat-treated mice. Therefore, our results suggest that Tat-SAG has potential as a therapeutic agent against ROS-related diseases such as PD.

Quantitative Evaluation of the Impact of Low-Voltage Loads due to Repetitive Voltage Sags

  • Yun Sang-Yun;Kim Jae-Chul;Moon Jong-Fil;Kang Bong-Seok
    • KIEE International Transactions on Power Engineering
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    • v.5A no.3
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    • pp.293-299
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    • 2005
  • Automatic reclosing is a typical protection method in power distribution systems for the clearing of temporary faults. However, it has a fatal weakness in regards to voltage sags because it produces repetitive voltage sags. In this paper, we explored the repetitive impact of voltage sag due to the automatic reclosing of power distribution systems. The actual tests of low voltage loads were carried out for obtaining the susceptibility of voltage sags. The final results of the tests yielded power acceptability curves of voltage sag, and the curves transformed the 3-dimensional CBEMA (Computer Business Equipment Manufacturer Association) format. For the quantitative evaluation of the impact of repetitive voltage sags, an assessment formulation using the voltage sag contour was proposed. The proposed formulation was tested by using the voltage sag contour data of IEEE standard and the results of the test. Through the case studies, we verified that the proposed method can be effectively used to evaluate the actual impact of repetitive voltage sags.