• Title/Summary/Keyword: S1PR3

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The Luminescent Properties of SrTiO$_3$ :Al, Pr Red Phosphor (Al과 Pr이 첨가된 SrTiO$_3$ 적색 형광체의 발광 특성)

  • 박정규;류호진;박희동;최승철
    • Journal of the Korean Ceramic Society
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    • v.36 no.5
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    • pp.478-482
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    • 1999
  • SrTiO3 :Al, Pr phosphor as an oxide compound phosphor is expect to be applied for a field emission display(FED). In this phosphor the excitation spectrum shows a different tendency according to an addition Al3+ and Pr3+ In this excitation spectrum the main peak at 359 nm represent excitation level of Pr3+(1S0longrightarrow1D2 transition) and the absorption characteristic according to Ti/Sr molar ratio is influenced by the structure symmetry. The emission spectrum exhibits the red luminescence with the radiative decay of the 1D2 states(1D2 longrightarrow3H4 transition) The concentration quenching phenomena at 1D2 state shows up as Al3+ and Pr3+ ion concentration increases.

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Effect of Maintained Microorganisms against to The Phytoncide on Pr. intermedia (피톤치드 처리 후의 잔존 구강 세균이 Pr. intermedia에 미치는 영향)

  • Park, Jae-Bong;Auh, Q-Schick;Chun, Yang-Hyun;Hong, Jung-Pyo
    • Journal of Oral Medicine and Pain
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    • v.34 no.2
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    • pp.153-167
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    • 2009
  • The present study was performed to observe the effect of phytoncide on oral normal microflora and the inhibitory effect of the surviving resident oral bacteria on Pr. intermedia. In this study, saliva from each of 20 healthy subjects was treated with 1% phytoncide from Japanese Hinoki (Chamaecyparis obtusa Sieb. et Zucc.). Surviving salivary bacteria were isolated on blood agar plates and identified by 16S rDNA sequencing. In order to select inhibitory isolates against Pr. intermedia, the isolates from the phytoncide-treated saliva were cultured with Pr. intermedia. The results were as follows: 1. Among the 200 surviving resident oral bacterium, 148(74.0%) bacterium inhibit the growth of Pr. intermedia on blood agar plates. 2. The 200 surviving resident oral bacterium were 109 Streptococcus salivarius(54.5%), 25 Streptococcus sanguinis(12.5%), 15 Streptococcus mitis(7.5%). 3. Among the 148 bacteria which inhibit Pr. intermedia, Streptococcus salivarius was 85.3%(93/109), Streptococcus sanguinis was 64.0%.(16/25), Streptococcus mitis was 54.3%(8/15), Streptococcus parasanguinis was 66.7%(6/9), and Streptococcus Alactolyticus was 100%(8/8). Taken together, among the surviving resident oral bacterium, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus mitis were mainly observed to inhibit Pr. intermedia. and they may exert an additional inhibitory activity against the periodontopathic bacterium. Therefore, phytoncide can be used for preventing and ceasing the progress of periodontal disease and halitosis, and thus is expect to promote oral health.

Sex Differences Associated With Hepatitis B Virus Surface Antigen Seropositivity Unwareness in Hepatitis B Virus Surface Antigen-positive Adults: 2007-2012 Korea National Health and Nutrition Examination Survey

  • Jang, Suk-Yong;Jang, Sung-In;Bae, Hong-Chul;Shin, Jaeyong;Park, Eun-Cheol
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.2
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    • pp.74-83
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    • 2015
  • Objectives: To examine the sex-specific factors associated with being unaware of one's hepatitis B virus surface antigen (HBsAg) seropositivity status in a large, HBsAg-positive population of Koreans. Methods: In total, 1197 subjects aged 19 years or older who were HBsAg-positive according to data from the 2007-2012 Korea National Health and Nutrition Examination Survey were included. Subjects were considered unaware of their HBsAg seropositivity status if they answered that they had no knowledge of being previously infected by the hepatitis B virus (HBV) or diagnosed with HBV hepatitis. Multivariate Poisson regression models with robust variance estimate were used to assess the significance of the variables using weighted frequencies. Results: The majority (77.8%) of HbsAg-positive Korean adults (females, 81.9%; males, 74.6%) were unaware of their HBsAg seropositivity status. We found that sex (female: prevalence ratio [PR] 1.19), household income (low: PR, 1.15), marital status (never married: PR, 1.18), self-rated health (moderate: PR, 1.14; good: PR, 1.12), and alcohol use (at least 2-3 times/wk: PR, 1.21) were associated with being unaware. In females, age (50 to 59 years: PR, 1.29; ${\geq}70$ years: PR, 1.30), household income (low: PR, 1.37; middle-low: PR, 1.24), and marital status (never married: PR, 1.33) were associated with being unaware. In males, self-rated health (moderate: PR, 1.14; good: PR, 1.21) and alcohol use (at least 2-3 times/wk: PR, 1.21) were associated with being unaware. Conclusions: Factors related to the socioeconomic status of females and the health-related behaviors of males were found to be associated with being unaware of one's HBsAg seropositivity status.

Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease

  • Song, Jae-Hwi;Kim, Goon-Tae;Park, Kyung-Ho;Park, Woo-Jae;Park, Tae-Sik
    • Biomolecules & Therapeutics
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    • v.29 no.4
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    • pp.373-383
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    • 2021
  • Atherosclerosis is the deposition of plaque in the main arteries. It is an inflammatory condition involving the accumulation of macrophages and various lipids (low-density lipoprotein [LDL] cholesterol, ceramide, S1P). Moreover, endothelial cells, macrophages, leukocytes, and smooth muscle cells are the major players in the atherogenic process. Sphingolipids are now emerging as important regulators in various pathophysiological processes, including the atherogenic process. Various sphingolipids exist, such as the ceramides, ceramide-1-phosphate, sphingosine, sphinganine, sphingosine-1-phosphate (S1P), sphingomyelin, and hundreds of glycosphingolipids. Among these, ceramides, glycosphingolipids, and S1P play important roles in the atherogenic processes. The atherosclerotic plaque consists of higher amounts of ceramide, glycosphingolipids, and sphingomyelin. The inhibition of the de novo ceramide biosynthesis reduces the development of atherosclerosis. S1P regulates atherogenesis via binding to the S1P receptor (S1PR). Among the five S1PRs (S1PR1-5), S1PR1 and S1PR3 mainly exert anti-atherosclerotic properties. This review mainly focuses on the effects of ceramide and S1P via the S1PR in the development of atherosclerosis. Moreover, it discusses the recent findings and potential therapeutic implications in atherosclerosis.

Rainfall Estimation Using TRMM-PR/VIRS and GMS Data (TRMM-PR/VIRS와 GMS 자료를 이용한 강수량 추정에 관한 연구)

  • 김영섭;박경원
    • Korean Journal of Remote Sensing
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    • v.18 no.6
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    • pp.319-326
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    • 2002
  • Rainfall estimation was conducted based on TRMM-PR/VIES and GMS data. AWS rainfall data were used for various validation. General procedure is as follows; 1) Z-R relationship was made by the comparison of TRMM-PR and AWS data. 2) new algorithm was developed by the estimates from Z-R equation and TBB of VIRS. 3) rainfall was estimated through the substitution of GMS data for TBB of VIRS in the newly developed algorithm. Z-R relationship based on TRMM is $Z=303R^{0.72}$ with correlation coefficient 0.57. The newly developed algorithm is shown as correlation coefficient 0.67 and RMSE 17mm/hr. New algorithm shows the underestimating tendency in case of heavy rainfall event.

$Pr^{3+}-and$ $Pr^{3+}/Er^{3+}$-Doped Selenide Glasses for Potential $1.6{\mu}m$ Optical Amplifier Materials

  • Choi, Yong-Gyu;Park, Bong-Je;Kim, Kyong-Hon;Heo, Jong
    • ETRI Journal
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    • v.23 no.3
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    • pp.97-105
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    • 2001
  • $1.6\;{\mu}m$ emission originated from $Pr^{3+}:\;(^3F_3,\;^3F_4)\;{\longrightarrow}\;^3H_4$ transition in $Pr^{3+}-\;and\;Pr^{3+}/Er^{3+}$-doped selenide glasses was investigated under an optical pump of a conventional 1480 nm laser diode. The measured peak wavelength and fullwidth at half-maximum of the fluorescent emission are ~1650nm and 120nm, respectively. A moderate lifetime of the thermally coupled upper manifolds of ${\sim}212{\pm}10{\mu}s$ together with a high stimulated emission cross-section of ${\sim}(3{\pm}1){\times}10^{-20}\;cm^2$ promises to be useful for $1.6{\mu}m$ band fiber-optic amplifiers that can be pumped with an existing high-power 1480 nm laser diode. Codoping $Er^{3+}$ enhances the emission intensity by way of a nonradiative $Er^{3+}:\;^4I_{13/2}\;{\longrightarrow}\;Pr^{3+}:\;(^3F_3,\;^3F_4)$ energy transfer. The Dexter model based on the spectral overlap between donor emission and acceptor absorption describes well the energy transfer from $Er^{3+}$ to $Pr^{3+}$ in these glasses. Also discussed in this paper are major transmission loss mechanisms of a selenide glass optical fiber.

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C-H…H-Fe Dihydrogen Bonding: Synthesis and Structure of $trans-[FeH(NCS(i-Pr)-S)(dppe)_2]I$ $(dppe=Ph_2PCH_2Ch_2PPh_2)$ (C-H…H-Fe Dihydrogen 결합: $trans-[FeH(NCS(i-Pr)-S)(dppe)_2]I$ 착물의 합성 및 구조)

  • 이지화;이순원
    • Korean Journal of Crystallography
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    • v.11 no.1
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    • pp.10-15
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    • 2000
  • Compound trans-[FeH(NCS(i-Pr)-S)(dppe)₂](1) reacted with isopropyl iodide (i-PrI) to give an Fe(II)-organic isothiocyanide complex, trans-[FeH(NCS(i-Pr)-S)(dppe)₂]I (2). Compound 2 was structurally characterized, in which the hydride ligand appears to be involved in the "dihydrogen" bonding, M-H…H-C. Crystallographic data for 2: monoclinic space group P2₁/n, a=13.490(2)Å, b=17.269(3)Å, c=21.384(3)Å, β=90.682(7)°, Z=4, R(wR₂)=0.0348(0.0894).

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A Semi-graphical Analysis on the Sublattice Anisotropy of a Two Sublattice System with Uniaxial Anisotropy: Application to Pr2Fe14B

  • Kim, Y.B.;Jin-Han-Min
    • Journal of Magnetics
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    • v.3 no.3
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    • pp.74-77
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    • 1998
  • A method to analyze the anisotropy constants of a two sublattice system with uniaxial anisotropy has been investigated by extending the Sucksmith and Thompson's method to higher order anisotropy terms. Using the method, a set of anisotropy constants for Pr-sublattice of $Pr_2Fe_{14}B at 4.2K has been obtained as K_{1Pr}=5210 J/kg, K_{2Pr}=-7200 J/kg, K_{3Pr}=-770 J/kg, K_{4Pr}=4940 J/kg and K_{SPr}=700 J/kg for N_{PrFe}=2.2 T/Am^2kg^{-1}.$ The magnetization calculated by an energy minimum method by using the sublattice anisotropy constants well reproduced the experimental results and satisfied the simulation assumptions.

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Development of a Screening System for Plant Defense-Inducing Agent using Transgenic Tobacco Plant with PR-1a Promoter and GUS Gene

  • Oh, Sang-Keun;Lee, Seon-Woo;Kwon, Suk-Yoon;Choi, Do-Il
    • The Plant Pathology Journal
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    • v.21 no.3
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    • pp.288-292
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    • 2005
  • Pathogenesis-related protein-1a (PR-1a) is strongly induced in tobacco plants by pathogen attack, exogenous salicylic acid (SA) application and by other developmental processes. In order to develop a rapid screening system for the selection of plant defense-inducing compounds originated from various sources, we have transformed tobacco Samsun NN plants with a chimeric construct consisting of GUS $(\beta-glucuronidase)$. In the $T_1$ generation, three transgenic lines having stable GUS expression were selected for further promoter analysis. Using GUS histochemical assay, we observed strong GUS induction driven by PR-1a promoter in PR1a-GUS transgenic tobacco leaves in response to the exogenous application of SA or benzol (1,2,3) thiadiazole-7-carbothioic acid S-methyl ester (BTH), a SA­derivative compound. In addition, GUS expression was maintained locally or systemically in PR1a-GUS transgenic line $\#5\;T_2$ generation) until after 3 days when they were treated with same chemicals. Our results suggested that the PR1a-GUS reporter gene system in tobacco plants may be applicable for the large-scale screening of defense-inducing substances.

The Effects of Peucedani Radix Herbal Acupuncture at St36 on Ovalbumin-induced Asthma in C57BL Mouse (전호약침(前胡藥鍼)이 Ovalbumin-induced Asthma Mouse Model에 미치는 영향)

  • Roh, Hong-Pyo;Seol, In-Chan;Kim, Yoon-Sik
    • Journal of Acupuncture Research
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    • v.22 no.6
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    • pp.1-15
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    • 2005
  • Objectives : The aim of this study was to investigate the effect of Peucedani Radix herbal acupuncture(PR-HA) at St36(joksamni) on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with OVA(ovalbumin) for 12 weeks(once a week) C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (3times a week). One of the two experimental groups was just treated with needle-prick on St36 and the other group was treated with 1% concentrations of PR-HAS at St36, for the later 8 weeks (3times /week). Results : 1. The weight and total cells of lung of the mice group treated with PR-HA decreased significantly compared with those of control group. 2. Total Leukocytes and Eosinophils in BALF of the mice group treated with PR-HA decreased significantly compared with those of control group. 3. Eosinophils in BALF of the mice group treated with PR-HA in Photomicrographs decreased significantly compared with those of control group. 4. According to Histological analysis of lung sections, it decreased significantly adhension of collagen in PR-HA than those of control group 5. The concentration of IgE, IL-4, IL-5, in BALF and IL-4, IL-5, Il-13 in serum of the mice group treated with PR-HA decreased significantly compared with that of control group. 6. The number of Gr-1+/CD11b+, CD11b+, CD3-/CCR3+, CD4+, CD3e+/CD69+ , CD23+B220+ cells in the lungs of the mice group treated with PR-HA decreased significantly compared with those of control group. 7. The cytokine's manifestation of mRNA of the mice group treated with PR-HA with RT-PCR decreased significantly compared with that of control group. Conclusion : We conclude that PR-HA is effective on OVA-induced asthma of C57BL/6 mouse.

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