• Korean Journal of Psychosomatic Medicine
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• v.17 no.2
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• pp.82-89
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• 2009

Objectives : Anxiety is a common co-morbid symptom in patients with epilepsy, which can affect the treatment and prognosis of epilepsy patients. This study is designed to compare the characteristics of anxiety between epilepsy patients and normal controls and also analyze them in epilepsy patients by examining both seizure-related and socio-demographic variables. Methods : As cross-sectional study, 80 epilepsy patients were enrolled from January to July 2008. The State-Trait Anxiety Inventory-(STAI) was used to assess the characteristics of anxiety. STAI is composed of transitory episodes of anxiety-(state subscale of STAI ; STAI-S) and stable personality features presenting chronic levels of anxiety-(trait subscale of STAI ; STAI-T). As controls, 113 healthy age-and sex-matched people were included. Results : The mean score of STAI-S and STAI-T were not different in both groups(STAI-S ; p=0.998, STAIT ; p=0.343). Within patients, patients without occupational engagement showed higher STAI-S(p<0.001) and tendency to higher STAI-T(p=0.052). Patients with depression showed higher score in both modalities(STAIS and STAI-T ; p<0.001). Patients with aura showed higher STAI-T(p=0.031). Conclusions : STAI-S and STAI-T was not significantly different between patients and controls. Of 3 factors related to anxiety, higher STAI-T in patients with aura is likely to represent misunderstanding internal and external changes as an aura and worrying about impending seizure. Occupational engagement and depression had relation to both STAI-S and STAI-T and more concern is needed to evaluate the risk of anxiety and manage it appropriately.

• Korean Journal of Clinical Pharmacy
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• v.21 no.2
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• pp.131-137
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• 2011

The purpose of this study was to evaluate the clinical efficacy of a standardized special ethanol extract from Gynostemma pentaphyllum as a management for anxiety and stress of normal population. This is a two-arm, parallelgroup, randomized, double blind clinical trial comparing Gynostemma pentaphyllum extract 200 mg bid (GP-EX, n=48) or placebo bid (n=54). The main outcome measures were the decrease in anxiety sensitivity index (ASI), the State version (S-STAI) of the Stait-Trait Anxiety Inventory (STAI) and the Trait version (T-STAT) of the STAI from baseline over a 6 weeks treatment period. In more anxious group (S-STAI50 or ASI19), the anxiety in group with GP-EX was decreased significantly than one in normal population with placebo [S-STAI50: T-STAI = from $57.7{\pm}6.5$ ($mean{\pm}S.D.$) to $46.8{\pm}11.2$ in normal population with GP-EX, p=0.002 vs. from $54.1{\pm}9.9$ to $49.0{\pm}9.6$ in normal population with placebo, p>0.05; ASI19: T-STAI = from $47.2{\pm}12.0$ to $42.4{\pm}11.1$ in normal population with GP-EX, p=0.022 vs. from $48.7{\pm}11.5$ to $46.0{\pm}10.4$ in normal population with placebo, p>0.05]. The most frequently reported adverse reactions considered possibly related to treatment were mild gastrointestinal events. GP-EX is more effective than placebo and is well tolerated as a therapy for anxiety and stress of normal population.

• The Journal of Korean Medicine
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• v.42 no.3
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• pp.72-85
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• 2021

Objectives: The objective of this study was to investigate the correlation of the scores on the State-Trait Anxiety Inventory-I (STAI-I), State-Trait Anxiety Inventory-II (STAI-II), Beck's Depression Inventory (BDI), and Core Seven Emotions Inventory-short form (CSEI-s) scales with pain improvement. Methods: We retrospectively investigated the medical records of 66 traffic accident inpatients who satisfy the selection criteria. They had received Korean medical treatment including acupuncture, electroacupuncture, pharmacopuncture, herbal medicine, and Chuna during hospitalization. STAI-II, BDI, and CSEI-s scores on hospital day 1, and STAI-I and numerical rating scale(NRS) scores on hospital day 1, 4, 7, and 10 were used for analysis. Pain improvement was evaluated by difference in NRS scores between hospital day 1 and hospital day 4, 7, 10. Results: The STAI-I, BDI, and CSEI-s scores showed significant correlations with pain or pain improvement. Conclusions: This study may be used in the research on psychological state and pain management of traffic accident patients and for patient education. Large-scale, well-designed studies need to be conducted in future to strengthen the results in this regard.

• Anxiety and mood
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• v.2 no.2
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• pp.136-141
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• 2006

Objectives : This study aimed to investigate the therapeutic effect of combined biofeedback training with pharmacotherapy for patients with anxiety disorder. Methods : 12 patients with panic disorder and generalized anxiety disorder were enrolled this study. They were tested for State Trait Anxiety Inventory-State (STAI-S), State Trait Anxiety Inventory-Trait (STAI-T), Beck's Depression Inventory (BDI) and Symptom CheckList-90-Revision Somatization (SCL-90-R-SOM) before and after the biofeedback training program. Results : The score of STAI-T (p=0.023) and BDI (p=0.0018) were the significantly decreased after the biofeedback training program. In Female group, the score of STAI-T (p=0.028), STAI-S (p=0.028) and BDI (p=0.009) were significantly decreased after the biofeedback training program. In the group which age is lower than 40 years old, the score of BDI (p=0.046) were significantly decreased after the biofeedback training program. In Panic disorder group, the score of STAI-S (p=0.046) were significantly decreased after the biofeedback training program. Conclusion : The result of this study is useful for the treating the anxiety disorder patients using the biofeedback training program.

• Sleep Medicine and Psychophysiology
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• v.26 no.2
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• pp.104-110
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• 2019

Objectives: Insomnia patients who visited the psychiatric outpatient of a university department, were divided into those patients with insomnia alone and those with depression or anxiety disorder, along with insomnia. The study analyzed their demographic characteristics and the differences in State-Trait Anxiety Inventory (STAI) results among the patient groups. Methods: Patients who visited the psychiatric department in Konkuk University hospital from 1 January 2006 to 31 December 2018. If they were diagnosed with insomnia disorder based on DSM IV-TR and had undergone STAI, their electronic records were retrospectively analyzed. Based on the records, the patients were classified into those with insomnia disorder only, those with insomnia and anxiety disorder, and those with insomnia and depressive disorder. This study analyzed the demographic characteristics and STAI results of each group, and compared the differences among those groups. Results: During the period, 99 of 329 insomnia disorder patients who had performed STAI were diagnosed with depressive concurrent disorder and 61 with concurrent anxiety disorder. There was no difference in demographic characteristics of age and sex ratio among the three patient groups, and all had greater than 70% proportions of patients aged from 50s to 70s (71.8%, 77.1%, and 73.8% respectively). The average scores of STAI-I were 51.85 ± 10.15 for the patients with anxiety disorders and 54.18 ± 10.32 for those with depressive disorders, both of which were higher than the score of the patients with insomnia alone (44.55 ± 8.89). However, the score difference was not statically significant between the anxiety and depression groups. Similarly, in the STAI-II comparison, the averages of patients with anxiety or depressive disorders along with insomnia were 49.98 ± 8.31 and 53.19 ± 10.13 respectively, which were higher than that of the insomnia only group (42.71 ± 8.84), but there was no significant difference between the anxiety and depressive disorder groups. Conclusion: Although there were no differences in demographic data between the patients with insomnia only and those with accompanying depressive or anxiety disorder, the STAI-I and II scores were lower in the insomnia only group. In the future, it is necessary to consider other demographic characteristics including comorbidities and to conduct similar analyses with a larger sample.

• Journal of Oriental Neuropsychiatry
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• v.26 no.4
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• pp.357-364
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• 2015

Objectives: The purpose of this study was to examine the effects of Korean medical treatment for Restless Legs Syndrome (RLS). Methods: We examined the effects of Korean medical treatment for patients with RLS who visited the neuropsychiatric clinic of Korean medicine. We treated the patient with herbal-medication, acupuncture, oriental psychotherapy. IRLS, STAI-X1,X2, BDI-2, BAI, STAXI-S,T were compared before and after 4 and 8 weeks of treatment to determine whether the symptoms and mood of patients were improved. Results: After 4 weeks treatment (n=13), STAI-X1,X2, BDI-2, BAI, STAXI-S scores increased significantly; whereas, IRLS and STAXI-T scores decreased. After 8 weeks treatment (n=8), IRLS, STAI-X1,X2, BDI-2, BAI scores increased significantly; whereas, STAXI-S scores decreased.Conclusions The treatment of RLS with Korean medicine was clinically efficient and resulted in improvement of the symptoms as well as psychological problems.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.1
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• pp.16-27
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• 2001

Objectives : This study was aimed to investigate stress and coping strategy in the families of schizophrenic patient, and changes of knowledge, stress and coping strategy after brief program of family education compared with control group Methods : The education group consisted of twenty four people who were families with schizophrenic patients and attended the brief program of family education. The control group consisted of twenty two people with schizophrenic inpatients. Self-report questionnaires such as Family Coping Questionnaire(FCQ), Patient Rejection Scale(PRS), Worry Questionnaire, Knowledge Questionnaire, Beck Depression Inventory(BDI), and State-Trait Anxiety Inventory(STAI) were administered to the education group and the control group, twice at the pre-test and post-test. Results : 1) In the education group, scores of worry questionnaire, BDI and STAI-S at the post-test were significantly lower than those at the pre-test. Social interests score of FCQ and knowledge questionnaire score at the post-test were significantly higher than those at the pre-test. In FCQ factors, social interests associated with avoidance strategy score at the post-test was significantly higher than that at the pre-test. However, in the control group, there was no significant difference in all questionnaires. 2) In the education group, significant positive correlation existed between calculated differences of worry questionnaire and STAI-S, and between worry questionnaire and STAI-T, whereas significant negative correlation existed between positive communication of FCQ and PRS, and between knowledge questionnaire and STAI-S. In the control group, significant negative correlation existed between information of FCQ and PRS, and between positive communication of FCQ and PRS. 3) In the education group, significant positive correlation existed between calculated differences of worry questionnaire and age of patient, whereas significant negative correlation existed between knowledge questionnaire and duration of illness. However, in the control group, there was no significant correlation. Conclusion : The brief program of family education was effective in increasing knowledge about schizophrenia, decreasing worry and anxiety about the patients in families with schizophrenic patient. In the education group as knowledge about schizophrenia increased, anxiety about schizophrenic patient decreased, but there was no significant correlation in the control group. As relative's rejection feeling about schizophrenic patient decreased, positive communication strategy increased in both groups. However, the control group was more affected by rejection feeling than the education group.

• Journal of Oriental Neuropsychiatry
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• v.23 no.3
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• pp.63-76
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• 2012

Objectives : The aim of this study was to investigate the value and efficacy of BDI, STAI, STAXI, ISI, and SCL-90-R in correlation with depression, anxiety, and insomnia patients. Methods : A total of 39 patients, who were diagnosed with depression, anxiety, and insomnia were evaluated using BDI, STAI, STAXI, ISI, and SCL-90-R. They were then statistically analyzed. Results : 1. BDI scores of depression patients were significantly different from other patients. 2. BDI scores of depression patients had strong positive correlation with STAI-S, and STAI-T scores. 3. STAI-S scores of anxiety patients had positive correlation with BDI, and ISI scores. 4. SCL-90-R depression subscale scores of depression patients had strong positive correlation with somatization, obsessive compulsive, interpersonal sensitivity, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, global severity index, and positive symptom total subscale scores. 5. SCL-90-R anxiety subscale scores of anxiety patients had strong positive correlation with somatization, obsessive compulsive, depression, phobic anxiety, and global severity index subscale scores. Phobic anxiety subscale scores had strong positive correlation with anxiety, global severity index, and positive symptom total subscale scores. Conclusions : The result findings are expected to serve as a useful resource in future stress-related depression, anxiety, and insomnia case reports and clinical research in oriental neuropsychiatry.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.2
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• pp.155-165
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• 2021

Background: This study aimed to assess the course of anxiety and pain during lower third molar (LTMo) surgery and explore the role of mobile and single-channel electroencephalography under clinical and surgical conditions. Methods: The State-Trait Anxiety Inventory (STAI), Corah's Dental Anxiety Scale (DAS), and Interval Scale of Anxiety Response (ISAR) were used. The patient self-rated anxiety (PSA), the pain felt during and after surgery, EEG, heart rate (HR), and blood pressure (BP) were assessed. Results: The Attention (ATT) and Meditation (MED) algorithms and indicators evaluated in this study showed several associations. ATT showed interactions and an association with STAI-S, pain during surgery, PSA level, HR, and surgical duration. MED showed an interaction and association with DAS, STAI-S, and pain due to anesthesia. Preclinical anxiety parameters may influence clinical perceptions and biological parameters during LTMo surgeries. High STAI-Trait and PSA scores were associated with postoperative pain, whereas high STAI-State scores were associated with more pain during anesthesia and surgery, as well as DAS, which was also associated with patient interference during surgery due to anxiety. Conclusions: The findings suggest that single-channel EEG is promising for evaluating brain responses associated with systemic reactions related to anxiety, surgical stress, and pain during oral surgery.

• Anxiety and mood
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• v.7 no.2
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• pp.85-91
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• 2011

Objective : This study aimed to investigate the characteristics of the early maladaptive schemas in patients with panic disorder. Methods : Patients (n=35) included people who had met the DSM-IV-TR criteria for panic disorder. The normal control group (n=35) were those people who had no psychiatric disorder and had never experienced panic attack. The early maladaptive schemas and the severity of depression and anxiety were assessed by the Young Schema Questionnaire Short-form (YSQ-SF), the Beck Depression Inventory (BDI), and the Spielberger State-Trait Anxiety Inventory (STAI). Results : The scores on the STAI-S, STAI-T, and BDI were significantly higher in the patient group. Compared to the control group, the scores of vulnerability to harm and illness, and abandonment/instability schemas were significantly higher in the patient group. In the patient group, defectiveness/shame and subjugation schemas were found to predict BDI, dependent/incompetence, abandonment/instability schemas were found to predict STAI-S, and vulnerability to harm and illness, and abandonment/instability schemas were found to predict STAI-T. In normal controls, failure and insufficient self-control/self-discipline, failure, and emotion inhibition schemas were found to predict BDI, STAI-T, and STAI-S. Conclusions : Vulnerability to harm and illness and abandonment/instability schemas may be characteristic schema in patients with panic disorder.