Clinical Characteristic of Anxiety in People with Epilepsy

간질 환자에서 보이는 불안의 임상적 특징

  • Kim, Sung-Hyouk (Department of Neurology, Gachon University Gil Hospital) ;
  • Kim, Suk-Ju (Department of Neuropsychiatry, Gachon University Gil Hospital) ;
  • Heo, Seon-Hee (Department of Graduate School of Medicine, Gachon University of Medicine and Science) ;
  • Park, Hyeon-Mi (Department of Neurology, Gachon University Gil Hospital)
  • 김성혁 (가천의과학대학교 길병원 신경과학교실) ;
  • 김석주 (가천의과학대학교 길병원 신경정신과학교실) ;
  • 허선희 (가천의과학대학교 의학전문대학원) ;
  • 박현미 (가천의과학대학교 길병원 신경과학교실)
  • Received : 2009.10.03
  • Accepted : 2009.11.29
  • Published : 2009.12.15

Abstract

Objectives : Anxiety is a common co-morbid symptom in patients with epilepsy, which can affect the treatment and prognosis of epilepsy patients. This study is designed to compare the characteristics of anxiety between epilepsy patients and normal controls and also analyze them in epilepsy patients by examining both seizure-related and socio-demographic variables. Methods : As cross-sectional study, 80 epilepsy patients were enrolled from January to July 2008. The State-Trait Anxiety Inventory-(STAI) was used to assess the characteristics of anxiety. STAI is composed of transitory episodes of anxiety-(state subscale of STAI ; STAI-S) and stable personality features presenting chronic levels of anxiety-(trait subscale of STAI ; STAI-T). As controls, 113 healthy age-and sex-matched people were included. Results : The mean score of STAI-S and STAI-T were not different in both groups(STAI-S ; p=0.998, STAIT ; p=0.343). Within patients, patients without occupational engagement showed higher STAI-S(p<0.001) and tendency to higher STAI-T(p=0.052). Patients with depression showed higher score in both modalities(STAIS and STAI-T ; p<0.001). Patients with aura showed higher STAI-T(p=0.031). Conclusions : STAI-S and STAI-T was not significantly different between patients and controls. Of 3 factors related to anxiety, higher STAI-T in patients with aura is likely to represent misunderstanding internal and external changes as an aura and worrying about impending seizure. Occupational engagement and depression had relation to both STAI-S and STAI-T and more concern is needed to evaluate the risk of anxiety and manage it appropriately.

연구목적 : 불안은 간질 환자에서 흔히 동반되는 증상이며, 간질의 치료와 경과에 영향을 주는 요인으로 알려져 있다. 본 연구는 간질 환자의 불안과 간질의 관련성을 알아보고자 시행하였다. 방법 : 2008년 1월부터 7월까지 80명의 간질 환자를 대상으로 하였고 상태-특성 불안 척도(State-Trait Anxiety Inventory ; STAI)를 이용하여 불안을 평가하였다. 대조군으로 113명의 정상 성인을 포함시켰다. 결과 : 상태불안과 특성불안 점수의 평균은 환자군과 대조군에서 차이가 없었다. 환자군 내에서 직업이 없는 환자와 우울이 있는 환자는 상태불안, 특성불안이 모두 높은 점수를 보였고 전조증상이 있는 환자들은 특성불안의 점수가 높았다. 결론 : 비록 간질 환자의 불안 정도가 정상 대조군보다 높다는 결과를 얻지는 못했지만, 간질 환자의 불안이 증상과 예후에 미칠 가능성이 있음을 알 수 있었다.

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