• 대한수의학회지
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• 제31권3호
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• pp.319-327
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• 1991

Gingko biloba is one of the oldest trees on earth. It can be traced 300 million years or more into past. In recent years, this tree has become increasingly popular because of its longevity. Amount of comsumption of Gingko leaves in Korea is increased to produce drugs for blood circulating system's disorder. The workers who work at the company of product drug with Gingko leaves complain pruritus at belt position of west, however toxic substance from extracts of Gingko biloba was carried out to determine what kind of the toxic substance from extract could induce a contact dermatitis by means of histopathological study. Dried leaves of Korean G. biloba were exhaustively extracted with chloroform. The aqueous chloroform residue was extracted with hexane. After evaporation, the hexane extract was passed through a silica gel column chromatography, it was separated into 9 fractions by means of gradient solvent (benzene: acetone/ 98~93 : 2~7%). The 4th and 7th fraction were idendified as bilibol and gingkolic acid by silica gel thin layer chromatography and NMR spectrophotometer. The 4th and 7th fractions of Korean Gingko leaves have an irritant substances which can be induced ear swelling and increased thickness of stratum cornium of rabbit ear exposed with the fractions (3 time/3 day, $100{\mu}l$ of 50mg/ml ethyl alcohol). In the 4th fraction, the substance have induced the surface of ear to swell and mass of unknown cell like inflammatory cell were infiltrated within the stratum corneum, and the 7th fraction have the surface of ear to loss the hairs, and sebaceous gland and follicle of hair were infiltrated with inflammatory cells. and other fractions at all did not induced a certain contact dermatitis and also Deutschen drug of Gingko (named as Gerigeron) have induced the contact dermatitis such as dematitis of Korean Gingko extract.

• 한국식품조리과학회지
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• 제25권6호
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• pp.703-711
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• 2009

Arabica coffee is classified for trading according to the New York Board of Trade(NYBOT) green coffee classification. NYBOT's grading system is based on classification derived from a defect count on a 300 g sample. In the present study, green and roasted coffees were investigated for possible correlations between the content of defective beans and sensory characteristics. Sensory evaluation was performed by expert tasters used by the Specialty Coffee Association of America(SCAA) cupping method. For green coffee, the percentage of defective beans increased. as the coffee grade decreased. Black and sour beans were not found in the NY2 grade coffee out of all natural, pulped natural, and washed coffee samples. Sour and insect damage were found in more natural coffee samples as the green coffee grade decreased. Green and broken beans were found in more washed coffee samples as the green coffee grade decreased. Flavor, clean, uniformity, aftertaste, and overall sensory characteristics were significantly different among the NY2, NY3/4 and NY4/5 grade coffee in all natural, pulped natural and washed coffee samples. The natural coffee in the NY2 sample presented the highest body characteristic. The pulped natural coffee in the NY2 sample presented the highest sweetness and balance characteristics. The washed coffee in the NY2 sample presented the highest acidity and flavor characteristics. In conclusion, the percentage of defective beans increased as sensory characteristics decreased.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.95-95
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• 2013

박막 공정 기술은 반도체 및 디스플레이뿐만 아니라 대부분의 전자소자에 적용되는 매우 중요한 기술이다. 그 중, 마그네트론 스퍼터링 공정은 플라즈마를 이용하여 금속 및 세라믹 등의 벌크 물질을 박막으로 증착 가능한 가장 널리 사용되는 방법 중의 하나이다. 하지만, Fe, Co, Ni 같은 강자성체 재료는 공정이 불가능하며, 스퍼터링 타겟 효율이 40% 이하이고, 제한적인 방전압력 범위 및 전류 상승에 의한 높은 전압 인가 제한이 있다는 단점이 있다. 본 연구에서 사용된 고밀도 플라즈마 소스를 적용한 고효율 스퍼터링 시스템은 할로우 음극을 이용한 원거리에서 고밀도 플라즈마를 생성하여 전자석 코일을 통해 자석이 없는 음극으로 이온을 수송시켜 스퍼터링을 일으킨다. 따라서 강자성체 재료의 스퍼터링이 가능하며, 90% 이상의 타겟 사용 효율 구현 및 기존 마그네트론 스퍼터링 대비 고속 증착이 가능하다. 또한, $10^{-4}$ Torr 압력영역에서 방전 및 스퍼터링이 가능하다. 타겟 이온 전류를 타겟 인가 전압과 관계없이 0~4 A까지, 타겟 이온 전류와 상관없이 타겟 인가 전압을 70~1,000 V 이상까지 독립적으로 제어가능하다. 또한 TiN과 같은 질소 반응성 공정에서 반응성 가스인 질소를 40%까지 넣어도 타겟에 수송되는 이온의 양에 영향이 없다. 할로우 음극 방전 전류 40 A에서 발생된 플라즈마의 이온에너지 분포는 55 eV에서 가우시안 분포를 보였으며, 플라즈마 포텐셜인 sheath drop은 74 V 였다. OES를 통한 광학적 진단 결과, 전자석에 의한 이온빔 초점에 따라 플라즈마 이온화율을 1.8배까지 증가시킬 수 있으며, 할로우 음극 방전 전류가 60~100 A로 증가하면서 플라즈마 이온화율을 6배까지 증가 가능하다. 또한, 타겟 이온 전류와 관계없이 타겟 인가 전압을 300~800 V로 증가시킴에 따라 Ar 이온 밀도의 경우 1.4배 증가, Ti 이온 밀도의 경우 2.2배 증가시킬 수 있었으며, TiN의 경우 증착 속도도 16~44 nm/min으로 제어가 가능하다.

• 한국실내디자인학회논문집
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• 제21권6호
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• pp.12-22
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• 2012

This study was carried out to focus on the user-oriented design of patients' room in general hospital. The purpose of the study was to examine the users' evaluation on their patients' rooms in H General Hospital and to suggest how to improve the patients' room design. The users were inpatients, care givers, and nurses, 300 subjects of each 100 users in H hospital. They evaluated 26 items related to the patients' room design using by 5-points Likert scale. Also, they answered three elements which bothered them, what needed improvement, and what they feel ill at ease. The results were as followings; 1) The users evaluated positively the location and size of window. This implies that the current one is relatively ideal and deserve to be maintained. 2) The users responded negatively to the thermostat system and the space for care-givers. 3) The lack of space for care-givers and visitors, common use of refrigerator and bathroom, and the lack of space bothered the users. 4) Most users mentioned the lack of space in patients' room. This implies that it needs to consider the change of the person number per patient's room, from 5 persons to 4 ones. 5) The lacks of sleeping space, dining space, and bathroom space bothered the care-givers. This implies that the space for care-givers such as sleeping, dinging, and bathing should be considered in patients' room.

• 해양환경안전학회지
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• 제2권1호
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• pp.57-65
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• 1996

The latest date, No. 1 YouII was grounded and sunk into the sea at MAMHYUNGJEDO ( South brother Island) in Sep. 21. 1995, and M.V. Sea Prince of V.L.C.C also made a big oil poullution accident owing to Typhoon "Paei" at front sea of Yeu Choun on Jul. 25. 1995. The large or small scall scale of oil poullution accident frequently was occurred about 300-350 cases per ine(1) year. The countries advanced in marine relations like as, nited Kingdom and Japan, have perfect system The country of expert education, training and oil recovery equipments in oil poullution accidents. The large quantity oil skimming ship's basic condition need general skimming ship which was high speed and large quantity skimming ability , and hve to store the recovered oil into tanks This oil skimming shop are composit the skimmer whuch move up and down according to the wace movements, storage tank which storage the recovered oil in after side, transfer pump which transformed from flooding tank to separating tank and separating tank which separated the oil mixtures, Also there are cylindrical floated which keep the auto positing, gate which keep the auto positing, gate which protect and guide the recovering oil from sea and balance weight for skimmer balance. Also there are cylindrical floated which keep the auto positing, gate which protect and guide the recovering oil from sea and balance weight for skimmer balance. The important arrangement is twin arm which moved by two hinge and move te skimming unit by wave movement. In gate of inside, made long wear in the gate bellow position, there are also connected the flexible hose for oil mixtures drop. The separating tank composited with multi-divided bulkhead for ffective oil and sea water separating by settling and flotation principle. As use the above natural princile and equipment, we can remove the large quantity oil by developed oil skimming ship.ming ship.

• 설비공학논문집
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• 제21권1호
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• pp.16-22
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• 2009

In order to investigate $CO_2$ heat transfer coefficient and pressure drop by PAG oil concentration during $CO_2$ evaporation, the experiment on evaporation heat transfer characteristics in a mini-channels were performed. The experimental apparatus consisted of a test section, a DC power supply, a heater, a chiller, a mass flow meter, a pump and a measurement system. Experiment was conducted for various mass fluxes($300{\sim}800kg/m^{2}s$), heat fluxes($10{\sim}40kW/m^2$) saturation temperatures($-5{\sim}5^{\circ}C$), and PAG oil concentration(0, 3, 5wt%). The variation of the heat transfer coefficient was different according to the oil concentration. With the increase of the oil concentration, the evaporation heat transfer coefficient decreased and the delay of dryout by oil addition was found. Pressure drop increased with the increase of the oil concentration and heat flux, and the decrease of saturation temperature.

• 약학회지
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• 제30권3호
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• pp.149-156
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• 1986

Many experiments have showed that the sodium and potassium ion transporting system and the Na, $^+K^+$-ATPase activity of membrane fragments are inhibited by digitalis glycosides and that the pump may be associated with the pharmacological receptor for the drugs. The aim of our investigation is to elucidate the ouabain binding sites occupation in heart following infusion of ouabain to intact animals by the $^3H$-ouabain binding assay. Lethal dose and 26 percent of lethal dose of ouabain were infused to intact rabbit through ear vein. Microsomal fraction was fractionated from ouabain treated rabbit heart. $^3H$-ouabain binding to these fraction in vitro was studied by the Schwartz's method. $^3H$-ouabain binding to heart microsomal fraction was also studied following infusion of ginseng ethanol extract and caffeine to rabbits respectively. 1) The infusion of lethal dose ouabain (113$\mu\textrm{g}$/kg) inhibited the specific $^3H$-ouabain binding to rabbit heart microsomal fraction to the level of 60% (p<0.01) of control group and the infusion of 26% of lethal dose of ouabain led to the level of 79% (p<0.01) of the control group. 2) Time course of binding of 0.4$\mu{M}$ $^3H$-ouabain to microsomal fraction from rabbit heart following infusion of lethal and 26% of lethal dose of ouabain showed dose dependence at various incubation time. 3) Compared with control, only slight change of $K_d$ and $B_{max}$ was detected in in vitro $^3H$-ouabain binding after infusion of ginseng ethanol extract (300mg/kg) to rabbit. 4) In caffeine infusion group, $^3H$-ouabain binding yielded nearly the same results as control group.

• Natural Product Sciences
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• 제18권3호
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• pp.177-182
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• 2012

Oxidative stress potentially induces neurotoxicity which is believed to underlie several major age-related diseases of the central nervous system. This study sought to identify the cytoprotective effects of sixty-nine Cambodian plants against glutamate-induced cell death. Cultured HT22 cells were applied as an in vitro model, and neurotoxicity was induced in these neuronal cells by exposure to a determined concentration of glutamate. Sixty-nine plant sources, as Cambodia's indigenous species, were purchased from O'reusey Market, Phnom Penh, and extracted with ethanol. These extracts were screened for cytoprotective effects against glutamate-triggered neurotoxicity in HT22 cells at concentrations of 100 and 300 ${\mu}g/ml$. Of these, eight ethanol extracts, bark of Anacardium occidentale, bark and sapwood of Bauhinia pulla, flowers of Borassus flabellifer, stems and leaves of Coix lacryma-jobi, bark and sapwood of Diospyros nitida, sapwood of Dipterocarpus obtusifolius, stems of Oryza rufipogon, and fruits of Phyllanthus emblica, showed significant cytoprotective effects against glutamate-induced cell damage and degeneration in HT22 cells.

• Journal of Korean Neurosurgical Society
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• 제39권6호
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• pp.471-474
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• 2006

Objective : Neuroimaging data are of paramount importance in making correct diagnosis. We herein evaluate the clinical usefulness of image transfer using cellular phones to facilitate neurological diagnosis and decision-making. Methods : Selected images from CT, MRI scans, and plain films obtained from 50 neurosurgical patients were transferred by cellular phones. A cellular phone with a built-in 1,300,000-pixel digital camera was used to capture and send the images. A cellular phone with a 262,000 color thin-film transistor liquid crystal display was used to receive the images. Communication between both cellular phones was operated by the same wireless protocol and the same wireless internet service. We compared the concordance of diagnoses and treatment plans between a house staff who could review full-scale original films and a consultant who could only review transferred images. These finding were later analyzed by a third observer. Results : The mean time of complete transfer was $2{\sim}3\;minutes$. The quality of all images received was good enough to make precise diagnosis and to select treatment options. Transferred images were helpful in making correct diagnosis and decision making in 49/50 [98%] cases. Discordant result was caused in one patient by improper selection of images by the house staff. Conclusion : The cellular phone system was useful for image transfer and delivery patient's information, leading to earlier diagnosis and initiation of treatment. This usefulness was due to sufficient resolution of the built-in camera and the TFT-LCD, the user-friendly features of the devices, and their low cost.

• 기본간호학회지
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• 제20권2호
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• pp.147-156
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• 2013

Purpose: The study was done to define complementary and alternative medicine (CAM) use among primary brain tumor patients and factors influencing use. Methods: The study was conducted with convenience sampling in 5 neuro-oncology centers in Seoul and Gyeonggi Province. Data were collected using a 25-item questionnaire developed by the researchers. Results: Of 250 patients approached, 231 (92.4%) agreed to participate. Overall, 26.8% of the respondents used CAM and the average cost for CAM use was 300,000 KRW. More than 72% of CAM users did not disclose CAM use to their health care professionals. The most frequently used therapy was natural products including mushrooms. Logistic regression analysis revealed that an education level of university or higher (OR=2.92, 95% CI=1.56-5.44, p=.001), unemployment (OR=1.99, 95% CI=1.04-3.80, p=.037), and WHO grade III & IV tumors (OR=2.18, 95% CI=1.07-4.72, p=.048) were significant factors influencing CAM use. Conclusion: Three out of ten brain tumor patients spend substantial sum of money for CAM. In these situations, health care professionals should be aware of this phenomenon and provide adequate information and consultation to the patients.