• Journal of Fisheries and Marine Sciences Education
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• v.24 no.6
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• pp.763-780
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• 2012

The purpose of this study was to develop the teaching & learning model to increase the key competencies in the university. For this, the researcher suggested the draft of teaching & learning model in the university based on literature analysis and survey for key competencies education to professors and students. After that, the draft of the model was revised through the formative test by experts. And then, the revised model was verified through delphi survey and a final model was fixed. As the result of this study, features of the final model are as follows. First, this study identified that a core values of teaching and learning model for the key competencies education in the university is reinforcement of learner's thinking skills and enhancement of field oriented on learning contents and reinforcement of professor's role as a mentor, a facilitator, a motivator, and an informant. Second, The core learning activity's process of the teaching and learning model for the key competencies education in the university consists of the following in order: team-building, exploring problem, gathering and analysing informations, arranging of leaning outcomes, comprehensive arrangement and self-examination.

• Honam Mathematical Journal
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• v.26 no.3
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• pp.247-256
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• 2004

Buchmann and Williams[1] proposed a key exchange system making use of the properties of the maximal order of an imaginary quadratic field. $H{\ddot{u}}hnlein$ et al. [6,7] also introduced a cryptosystem with trapdoor decryption in the class group of the non-maximal imaginary quadratic order with prime conductor q. Their common techniques are based on the properties of the invertible ideals of the maximal or non-maximal orders respectively. Kim and Moon [8], however, proposed a key-exchange system and a public-key encryption scheme, based on the class semigroups of imaginary quadratic non-maximal orders. In Kim and Moon[8]'s cryptosystem, a non-invertible ideal is chosen as a generator of key-exchange ststem and their secret key is some characteristic value of the ideal on the basis of Zanardo et al.[9]'s quantity for ideal equivalence. In this paper we propose the methods for finding the non-invertible ideals corresponding to non-primitive quadratic forms and clarify the structure of the class semigroup of non-maximal order as finitely disjoint union of groups with some quantities correctly. And then we correct the misconceptions of Zanardo et al.[9] and analyze Kim and Moon[8]'s cryptosystem.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.4031-4036
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• 2012

Background: The negative signaling provided by interactions of the co-inhibitory molecule, programmed death-1 (PD-1), and its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2), is a critical mechanism contributing to tumor evasion; blockade of this pathway has been proven to enhance cytotoxic activity and mediate antitumor therapy. Here we evaluated the anti-tumor efficacy of AAV-mediated delivery of the extracellular domain of murine PD-1 (sPD-1) to a tumor site. Material and Methods: An rAAV vector was constructed in which the expression of sPD-1, a known negative regulator of TCR signals, is driven by human cytomegalovirus immediate early promoter (CMV-P), using a triple plasmid transfection system. Tumor-bearing mice were then treated with the AAV/sPD1 construct and expression of sPD-1 in tumor tissues was determined by semi quantitative RT-PCR, and tumor weights and cytotoxic activity of splenocytes were measured. Results: Analysis of tumor homogenates revealed sPD-1 mRNA to be significantly overexpressed in rAAV/sPD-1 treated mice as compared with control levels. Its use for local gene therapy at the inoculation site of H22 hepatoma cells could inhibit tumor growth, also enhancing lysis of tumor cells by lymphocytes stimulated specifically with an antigen. In addition, PD-1 was also found expressed on the surfaces of activated CD8+ T cells. Conclusion: This study confirmed that expression of the soluble extracellular domain of PD-1 molecule could reduce tumor microenvironment inhibitory effects on T cells and enhance cytotoxicity. This suggests that it might be a potential target for development of therapies to augment T-cell responses in patients with malignancies.

• Korean Journal of Materials Research
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• v.30 no.12
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• pp.641-649
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• 2020

A facile microwave assisted solvothermal process is designed for fabricating SnS nanoparticles decorated on graphene nanosheet, which used as visible light driven photocatalyst. Some typical characterization techniques such as XRD, FT-IR, SEM with EDX analysis, and TEM and BET analysis are used to analyse the physical characteristics of as-prepared samples. Spherical SnS nanoparticles are uniformly dispersed on the surface of graphene nanosheet due to ammonia, which can prevent the aggregation of graphene oxide. Meanwhile, microwave radiation provides fast energy that promotes the formation of spherical SnS nanoparticles within a short time. The visible light photocatalytic activity of as-prepared SnS-GR nanocomposites is analysed through photodegradation efficiency of methylene blue with high concentration. According to the higher photocatalytic property, the as-prepared SnS-GR nanocomposites can be expected to be an efficient visible light driven photocatalyst. After five cycles for decolorization, the rate decreases from 87 % to 78 % (about 9 %). It is obvious that the photocatalytic activity of SnS-GR nanocomposite has good repeatability.

• The Research Journal of the Costume Culture
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• v.22 no.3
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• pp.481-502
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• 2014

This study intended to identify the relationship between textile print designs for local apparel, and fashion trends. This was achieved by extracting trend key words and analyzing apparel textiles. The fashion trends and print trends from the 2010S/S season to the 2013F/W season as projected by two trend forecasters, the Samsung Fashion Institute and First View Korea, were extracted for a comparative analysis. In terms of clothing patterns, a total of 1,582 print designs purchased by local apparel brands targeting women in their 20s and 30s from print design companies including Italy's NEWAGE, MyDesign and England's Pattern, were analyzed. After classifying the designs according to the trend key words which had been extracted, the demands by season, trend dependency, and design preferences were analyzed to produce the following results. The major key words for textile print designs from the 2010S/S season to the 2013F/W season were Check & Stripe, Flower, Geometric, Natural, Ethnic, and Graphical. Patterns corresponding to those design key words were more prominent in recent designs. Considering the trends by season, the designs presented in the F/W season were found to be more likely to correspond to the trend key words than those in the S/S season. A general preference for nature-inspired designs was also found in the local print market.

• IEIE Transactions on Smart Processing and Computing
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• v.2 no.3
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• pp.168-175
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• 2013

Key escrow is a default property that is inherent in identity-based cryptography, where a curious private key generator (PKG) can derive a secret value shared by communicating entities in its domain. Therefore, a dishonest PKG can encrypt and decrypt ciphers or can carry out any attack on the communicating parties. Of course, the escrow property is not completely unwanted but is acceptable in other particular applications. On the other hand, in more civil applications, this key escrow property is undesirable and needs to be removed to provide maximum communication privacy. Therefore, this paper presents an escrow-free identity-based key agreement protocol that is also applicable even in a distinct PKG condition that does not use pairings. The proposed protocol has comparable computational and communicational performance to many other protocols with similar security attributes, of which their security is based on costly bilinear pairings. The protocol's notion was inspired by McCullagh et al. and Chen-Kudla, in regard to escrow-free and multi-PKG key agreement ideas. In particular, the scheme captures perfect forward secrecy and key compromise impersonation resilience, which were lacking in McCullagh et al.'s study, as well as all other desirable security attributes, such as known key secrecy, unknown key-share resilience and no-key control. The merit in the proposed protocol is the achievement of all required security requirements with a relatively lower computational overhead than many other protocols because it precludes pairings.

• Nuclear Engineering and Technology
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• v.52 no.1
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• pp.59-68
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• 2020

ECCMIX component was introduced in RELAP5/MOD3 for calculating the interfacial condensation. Compared to other existing components in RELAP5, user experience of ECCMIX component is restricted to developmental assessment applications. To evaluate the capability of the ECCMIX component, ECCS experiment was conducted which included single-phase and two-phase thermal mixing. The experiment was carried out with test sections containing a main pipe (70 mm inner diameter) and a branch pipe (21 mm inner diameter) under the atmospheric pressure. The steam mass flow in the main pipe ranged from 0 to 0.0347 kg/s, and the subcooled water mass flow in the branch pipe ranged from 0.0278 to 0.1389 kg/s. The comparison of the experimental data with the calculation results illuminated that although the ECCMIX component was more difficult to converge than Branch component, it was a more appropriate manner to simulate interfacial condensation under two-phase thermal mixing circumstance, while the two components had no differences under single-phase circumstance.

• BMB Reports
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• v.41 no.10
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• pp.733-738
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• 2008

Although previous studies have implicated a role for TC1 (C8orf4) in cancer cell proliferation, the molecular mechanism of its action is still largely unclear. In this study, we showed, for the first time, that the mRNA levels of TC1 were upregulated by mitogens (FBS/thrombin) and at least partially, through the ERK1/2 signaling pathway. Interestingly, the over-expression of TC1 promoted the $G_1$- to S-phase transition of the cell cycle, which was delayed by the deficiency of ERK1/2 signaling in fibroblast cells. Furthermore, the luciferase reporter assay indicated that the over-expression of TC1 significantly increased Cyclin D1 promoter-driven luciferase activity. Taken together, our findings revealed that TC1 was involved in the mitogen-activated ERK1/2 signaling pathway and positively regulated $G_1$- to S-phase transition of the cell cycle. Our results may provide a novel mechanism of the role of TC1 in the regulation of cell proliferation.

• International Journal of Naval Architecture and Ocean Engineering
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• v.6 no.3
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• pp.626-637
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• 2014

On ship, especially on large ship, the flexure deformation between Master (M)/Slave (S) Inertial Navigation System (INS) is a key factor which determines the accuracy of the integrated system of M/S INS. In engineering this flexure deformation will be increased with the added ship size. In the M/S INS integrated system, the attitude error between MINS and SINS cannot really reflect the misalignment angle change of SINS due to the flexure deformation. At the same time, the flexure deformation will bring the change of the lever arm size, which further induces the uncertainty of lever arm velocity, resulting in the velocity matching error. To solve this problem, a $H_{\infty}$ algorithm is proposed, in which the attitude and velocity matching error caused by deformation is considered as measurement noise with limited energy, and measurement noise will be restrained by the robustness of $H_{\infty}$ filter. Based on the classical "attitude plus velocity" matching method, the progress of M/S INS information fusion is simulated and compared by using three kinds of schemes, which are known and unknown flexure deformation with standard Kalman filter, and unknown flexure deformation with $H_{\infty}$ filter, respectively. Simulation results indicate that $H_{\infty}$ filter can effectively improve the accuracy of information fusion when flexure deformation is unknown but non-ignorable.

• International Journal of Control, Automation, and Systems
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• v.6 no.6
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• pp.915-927
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• 2008

Networked control systems(NCSs) have gained increasing attention in recent years due to their advantages and potential applications. The network Quality-of-Service(QoS) in NCSs always fluctuates due to changes of the traffic load and available network resources. To handle the network QoS variations problem, this paper presents an intelligent scheduling control method for NCSs, where the sampling period and the control parameters are simultaneously scheduled to compensate the effect of QoS variation on NCSs performance. For NCSs with network-induced delays and packet dropouts, a discrete-time switch model is proposed. By defining a sampling-period-dependent Lyapunov function and a common quadratic Lyapunov function, the stability conditions are derived for NCSs in terms of linear matrix inequalities(LMIs). Based on the obtained stability conditions, the corresponding controller design problem is solved and the performance optimization problem is also investigated. Simulation results are given to demonstrate the effectiveness of the proposed approaches.