• Title/Summary/Keyword: S/M ratio

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Cap Formation Process for MEMS Packages using Cu/Sn Rim Bonding (Cu/Sn Rim 본딩을 이용한 MEMS 패키지의 Cap 형성공정)

  • Kim, S.K.;Oh, T.S.;Moon, J.T.
    • Journal of the Microelectronics and Packaging Society
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    • v.15 no.4
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    • pp.31-39
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    • 2008
  • To develop the MEMS cap bonding process without cavity formation, we electroplated Cu/Sn rim structures and measured the bonding characteristics for the Cu/Sn rims of $25{\sim}400{\mu}m$ width. As the effective device-mounting area ratio decreased and the failure strength ratio increased for wider Cu/Sn rim, these two properties were estimated to be optimized for the Cu/Sn rim with 150 ${\mu}m$ width. Complete bonding was accomplished at the whole interfaces of the Cu/Sn packages with the rim widths of 25 ${\mu}m$ and 50 ${\mu}m$. However, voids were observed locally at the interfaces with the rim widths larger than 100 ${\mu}m$. Such voids were formed by local non-contact between the upper and lower rims due to the surface roughness of the electroplated Sn.

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Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling

  • Yang, Kyeong-Eun;Jang, Hyun-Jin;Hwang, In-Hu;Hong, Eun Mi;Lee, Min-Goo;Lee, Soon;Jang, Ik-Soon;Choi, Jong-Soon
    • Journal of Ginseng Research
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    • v.44 no.2
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    • pp.341-349
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    • 2020
  • Background: The replicative senescence of human dermal fibroblasts (HDFs) is accompanied by growth arrest. In our previous study, the treatment of senescent HDFs with Rg3(S) lowered the intrinsic reactive oxygen species (ROS) levels and reversed cellular senescence by inducing peroxiredoxin-3, an antioxidant enzyme. However, the signaling pathways involved in Rg3(S)-induced senescence reversal in HDFs and the relatedness of the stereoisomer Rg3(R) in corresponding signaling pathways are not known yet. Methods: We performed senescence-associated β-galactosidase and cell cycle assays in Rg3(S)-treated senescent HDFs. The levels of ROS, adenosine triphosphate (ATP), and cyclic adenosine monophosphate (cAMP) as well as the mitochondrial DNA copy number, nicotinamide adenine dinucleotide (NAD)+/1,4-dihydronicotinamide adenine dinucleotide (NADH) ratio, and NAD-dependent sirtuins expression were measured and compared among young, old, and Rg3(S)-pretreated old HDFs. Major signaling pathways of phosphatidylinositol 3-kinase/Akt, 5' adenosine monophosphate-activated protein kinase (AMPK), and sirtuin 1/3, including cell cycle regulatory proteins, were examined by immunoblot analysis. Results: Ginsenoside Rg3(S) reversed the replicative senescence of HDFs by restoring the ATP level and NAD+/NADH ratio in downregulated senescent HDFs. Rg3(S) recovered directly the cellular levels of ROS and the NAD+/NADH ratio in young HDFs inactivated by rotenone. Rg3(S) mainly downregulated phosphatidylinositol 3-kinase/Akt through the inhibition of mTOR by cell cycle regulators like p53/p21 in senescent HDFs, whereas Rg3(R) did not alter the corresponding signaling pathways. Rg3(S)-activated sirtuin 3/PGC1α to stimulate mitochondrial biogenesis. Conclusion: Cellular molecular analysis suggests that Rg3(S) specifically reverses the replicative senescence of HDFs by modulating Akt-mTOR-sirtuin signaling to promote the biogenesis of mitochondria.

A Study of Lorentz-Meutzner's Two Evaporator Refrigeration System Using Alternative Refrigerant Mixtures (대체혼합냉매를 사용하는 Lorentz-Meutzner의 이중 증발기 냉동 시스템의 성능에 관한 연구)

  • Park, Y.M.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.4 no.2
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    • pp.123-136
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    • 1992
  • A preliminary thermodynamic design model of two-evaporator refrigerator/freezer system is constructed. This system is based on Lorentz-Meutzner cycle using refrigerant mixtures. This model screens alternative refrigerant (R32, R125, R143a, R22, R134a, R152a, R124, R142b, R123) mixtures to select the best performance-giving refrigerant mixtures and its composition for the system. Also, it estimates the effects of cooling temperatures of intercoolers, evaporator's area ratio, cooling load ratio on the performance of the system. The COP of the system ranges from 1.4 to 1.6, which is superior to that of the single evaporator system charged with R12 by 13% to 29%. Among 15 mixtures, R22/R123, R143a/R123, R32/R142b, and R32/R124 (in the order of high COP) are most recommendable. For the case of R22/R123, R22 mass fraction more than 0.5(Load Ratio=1.0) or 0.7(Load Ratio=0.33) is recomended in order to replace R12 without reduction in volumetric capacity when keeping the compressor as the same one. COP has the highest value with X(R22)=0.7 and 0.8, respectively. For the case of R143a/R123, in the similar manner, mass fraction of R143a is more than 0.5 or 0.6 while best performance occurs at X(R143a)=0.8. Higher temperature intercooler is more important for the performance of the system than lower temperature intercooler. The area ratio of evaporators is roughly proportional to load ratio of the evaporators.

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Determination of Solidified Material's Optimum Mixing Ratio for Reservoir Embankment Reinforcement (저수지 제체 보강을 위한 고화재 최적 배합비 결정)

  • Jaegeun Woo;Jungsoon Hwang;Seungwook Kim;Seungcheol Baek
    • Journal of the Korean GEO-environmental Society
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    • v.25 no.6
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    • pp.5-12
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    • 2024
  • Currently, a grouting method that minimizes damage to the reservoir embankment by injecting solidification agent at low pressure is commonly used to ensure waterproofing and safety of the embankment, but the use of solidification agents can cause issues, such as a decrease in durability and a lack of clear method for determining the mixing ratio. In this study, when the base ground and solidification agent were stirred and mixed at various weight mixing ratios, the permeability coefficient and strength of the mixture were confirmed through laboratory tests, and the optimal mixing ratio was suggested through analysis of the test results. The specimen for the laboratory test was produced considering the mixing ratio of the solidification agent. The specimen for the permeability coefficient test was tested by producing one each of cohesionless and cohesive soil for a mixing amount of 1.5 kN/m3 of solidification agent, and the permeability test results confirmed that the water barrier performance was secured below the permeability coefficient value required by various design criteria. A total of 24 specimens for the strength test were produced, 3 for each of 5 mixing amounts for cohesive soil and 3 mixing amounts for cohesionless soil. The strength test results showed that the uniaxial compressive strength tends to increase linearly with increasing curing time for both cohesionless soil and cohesive soil when the mixing amount is less than 2.0 kN/m3. Therefore, the optimal mixing ratio applied to the site is determined to be mixing amount of 1.5 kN/m3 and 2.0 kN/m3. Finally, numerical analysis reflecting test results was conducted on design case for improvement projects for aging reservoirs embankment to verify the water barrier performance and safety improvement effects.

Convective Heat Transfer Characteristics on a Plate Cooled by Rectangular Water Jets (사각수분류에 의한 평판상에서의 대류열전달 특성)

  • Kim, Uen-Young;Jeon, Sung-Taek;Park, Jong-Suen;Lee, Doug-Bong
    • Solar Energy
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    • v.15 no.1
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    • pp.53-71
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    • 1995
  • Experiments have been conducted on a planar, free surface jet of water to investigate the effects of aspect ratios(AR=6.67, 15, 26.67), average nozzle velocity($V_0=3.3m/s{\sim}78m/s$) and nozzle-to-plate spacings($Z/W=6{\sim}40$) on the characteristics of heat transfer, when 3 rectangular waterjets impinging on a flat plate which has the uniform heat flux. the scondary peaks which produced by circular jets also produced by rectangular water jets. The position of the scondary peaks depends upon the aspect ratio of nozzle. The heat transfer coefficient was subjected to the influence of aspect ratio. The heat transfer correlations and best position of nozzles which produced maximum heat transfer coefficient at stagnation point are provided.

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Analysis of geological conditions and water bearing zones in front of tunnel face using TSP (TSP탐사를 이용한 터널 굴착면 전방 지질상태 및 함수대 분석)

  • Kyounghak Lim;Yeonjun Park
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.25 no.5
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    • pp.373-386
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    • 2023
  • To analyze the prediction of geological conditions and water-bearing zones, TSP was performed in the collapse zone of the fault zone. The results of the TSP were verified by comparing them to the face mapping results of the prediction zone. The rock quality prediction result of the TSP had an error of about 3 to 10 meters compared to the face mapping result, but the overall rock quality change and ground condition were analyzed to be relatively similar. In the water-bearing zones of the face mapping results, the Vp/Vs ratio ranges from 1.79 to 2.37 and the Poisson's ratio ranges from 0.27 to 0.39. In the sections other than the water-bearing zones, the Vp/Vs ratio ranges from 1.61 to 1.89, and the Poisson's ratio ranges from 0.19 to 0.3. As a result of analyzing the Vp/Vs ratio and Poisson's ratio in the water-bearing zones, it is analyzed that the sections with a Vp/Vs ratio of 2.0 or more and a Poisson's ratio of 0.3 or more have a high possibility of being water-bearing zones.

Performance Evaluation and Design of an Edible Fresh Corn Harvesting Machine (식용 풋옥수수 수확 시험장치 설계 및 성능평가)

  • Kang, Na Rae;Choi, Il Su;Kim, Young Keun;Choi, Yong;Yu, Seung Hwa;Woo, Jea Keun;Hyun, Chang Sik;Kim, Sung Kook
    • Journal of Drive and Control
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    • v.16 no.4
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    • pp.74-79
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    • 2019
  • In this study, an edible fresh corn harvest testing machine was designed and manufactured. And harvesting performance was analyzed through the field test. The testing machine is of the tractor attached type. It is connected to the tractor PTO shaft to transfer power to the each part of the harvesting machine. And it harvests fresh corn by one row through the processes of cutting, stem crushing, detaching, and collecting. The performance test was performed at PTO speed (540, 750, 1050 rpm, respectively), working speed (0.1, 0.15, 0.2 m/s, respectively), and cropping cultivation (row spacing·hill spacing 70·25 cm, 70·40 cm, 90·30 cm, respectively). The performance test was repeated three times in the 15 m section. The detachment loss ratio, uncollected crop ratio, damage ratio, and harvest ratio were analyzed. As a result of the performance test, it was analyzed that the PTO speed 540 rpm, running speed of 0.1 m/s, and row spacing·hill spacing 70·40 cm were the optimal condition.

Studies of the Thuja orientalis(4) -Effect of the Thuja biotae water extract on blood glucose, hydroperoxid cholesterol, triglyceride and fatty acid composition in rabbit- (측백열매에 관한 연구(4) -과피의 물추출액이 토끼의 혈장콜레스테롤, 혈당, 과산화지질 및 지방산 분포에 미치는 영향-)

  • Nam, Hyun-Keun;Chung, Young-Tae;Rho, Gi-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.18 no.4
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    • pp.371-374
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    • 1989
  • The effect of Thuja biotae water extract on lipid composition, blood glucose, cholesterol, triglyceride and lipid hydroperoxide was studied in rabbits. In the animalfed Thuja biotae water extract $1m{\ell}/kg\;or\;2m{\ell}/kg$, blood glucose, cholesterol, triglyceride and lipid hydroperoxide was lower values than the control group. The lipid composition of plasma was not great differencies, but palmitic acid $C_{16:0}$ was very elevated with higher than 50%, n-3/n-6 ratio was higher than 0.3 and p/s ratio was higher than 4.0. It was concluded that Thuja biotae water extract may be one of the blood glucose, cholesterol and triglyceride level lowering factor.

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Function of Blending Essential Oil in the Development of Anti-Dandruff Products

  • Yuk, Young Sam
    • International Journal of Internet, Broadcasting and Communication
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    • v.14 no.3
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    • pp.171-181
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    • 2022
  • Purpose: In this paper, we show our blending ratio of 10 types of Essential Oils that survives beneficial bacteria and kills harmful bacteria in the scalp, and we investigate the possibility of application of our blending ratio to the development of anti-dandruff products and the possibility of being used as a raw material for clinical beauty and customized cosmetics. Methods: The scalp microorganisms used in our study were M. furfur, S. epidermidis, E. coli, and P. nitroreducens. There are a total of 10 Essential Oils such as True Lavender, Lime, Roman chamomile, Rosemary camphor, Cedarwood, Geranium, Clove, Tea tree, Palmalosa, and Peppermint. The antibacterial test of the blended Essential Oil was carried out according to the test method of the standardized evaluation methodology of "Food and Food Additives Code". Since M. furfur is related to the growth of sebum in the scalp, in this study we used the fnLNB and the fnLNA with 20 ㎖ of whole fat cow milk added. Results: The blending ratio of EO, which inhibits dandruff-causing bacteria such as M. furfur, S. epidermidis, E. coli, and does not inhibit P. nitroreducens showing dominant growth in a healthy scalp, was B8(Clove 0.2%, Roman chamomile 0.5%, Tea tree 0.3%), B9(Geranium 0.1%, Palmarosa 0.1%, Roman chamomile 0.5%, Tea tree 0.3%), B10(Clove 0.1%, Geranium 0.1%, Palmarosa 0.1%, Roman chamomile 0.5%, Tea tree 0.2%). Conclusion: It is thought that the blending ratio of BEO obtained as a result of this study can provide a basis for use as an alternative to antibiotics in developing anti-dandruff drugs and emerge as a new alternative to solve scalp microbial imbalance. In order for EO to be used as a useful raw material for anti-dandruff preparation, researches on 1) Standardization (the effects of products differ according to the types, regions, climate, extraction methods, etc.), 2) Antimicrobial effects, 3) Safety, etc., must be established.

Time dependent equations for the compressive strength of self-consolidating concrete through statistical optimization

  • Hossain, K.M.A.;Lachemi, M.
    • Computers and Concrete
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    • v.3 no.4
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    • pp.249-260
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    • 2006
  • Self-consolidating concrete (SCC) in the fresh state is known for its excellent deformability, high resistance to segregation, and use, without applying vibration, in congested reinforced concrete structures characterized by difficult casting conditions. Such a concrete can be obtained by incorporating either mineral or chemical admixtures. This paper presents the results of an investigation to asses the applicability of Abram's law in predicting the compressive strength of SCC to any given age. Abram's law is based on the assumption that the strength of concrete with a specific type of aggregate at given age cured at a prescribed temperature depends primarily on the water-to-cement ratio (W/C). It is doubtful that such W/C law is applicable to concrete mixes with mineral or chemical admixtures as is the case for SCC where water to binder ratio (W/B) is used instead of W/C as the basis for mix design. Strength data of various types of SCC mixtures is collected from different sources to check the performance of Abram's law. An attempt has been made to generalize Abram's law by using various optimization methodologies on collected strength data of various SCC mixtures. A set of generalized equations is developed for the prediction of SCC strength at various ages. The performance of generalized equations is found better than original Abram's equations.