• 대한치과교정학회지
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• 제50권6호
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• pp.391-400
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• 2020

Objective: Increased gingival elasticity has been implicated as the cause of relapse following orthodontic rotational tooth movement and approaches to reduce relapse are limited. This study aimed to investigate the effects of sulforaphane (SFN), an inhibitor of osteoclastogenesis, on gene expression in gingival fibroblasts and relapse after rotational tooth movement in beagle dogs. Methods: The lower lateral incisors of five beagle dogs were rotated. SFN or dimethylsulfoxide (DMSO) were injected into the supra-alveolar gingiva of the experimental and control group, respectively, and the effect of SFN on relapse tendency was evaluated. Changes in mRNA expression of extracellular matrix components associated with gingival elasticity in beagles were investigated by real-time polymerase chain reaction. Morphology and arrangement of collagen fibers were observed on Masson's trichrome staining of buccal gingival tissues of experimental and control teeth. Results: SFN reduced the amount and percentage of relapse of orthodontic rotation. It also decreased the gene expression of lysyl oxidase and increased the gene expression of matrix metalloproteinase (MMP) 1 and MMP 12, compared with DMSO control subjects. Histologically, collagen fiber bundles were arranged irregularly and were not well connected in the SFN-treated group, whereas the fibers extended in parallel and perpendicular directions toward the gingiva and alveolar bone in a more regular and well-ordered arrangement in the DMSO-treated group. Conclusions: Our findings demonstrated that SFN treatment may be a promising pharmacologic approach to prevent orthodontic rotational relapse caused by increased gingival elasticity of rotated teeth in beagle dogs.

• 대한기계학회논문집B
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• 제28권8호
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• pp.976-983
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• 2004

In high-density hard disk drives, the slider should be made to fly close to the magnetic recording disk to generate better signal resolution and at an increasingly high velocity to achieve better data rate. The slider disk interaction in CSS (contact-start-stop) mode is an important source of particle generation. Contamination particles in the hard disk drive can cause serious problems including slider crash and thermal asperities. We investigated the number and the sizes of particles generated in the hard disk drive, operating at increasing disk rotational speeds, in the CSS mode. CNC (condensation nucleus counter) and PSS (particle size selector) were used for this investigation. In addition, we examined the particle components by using SEM (scanning electron microscopes), AES (auger electron spectroscopy), and TOF-SIMS (time of flight-secondary ions mass spectrometry). The increasing disk rotational speed directly affected the particle generation by slider disk interaction. The number of particles that were generated increased with the disk rotational speed. The particle generation rate increased rapidly at motor speeds above 8000 rpm. This increase may be due to the increased slider disk interaction. Particle sizes ranged from 14 to 200 nm. The particles generated by slider disk interaction came from the lubricant on the disk, coating layer of the disk, and also slider surface.

• Biotechnology and Bioprocess Engineering:BBE
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• 제9권5호
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• pp.374-378
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• 2004

The effects of various environmental factors such as pH (5, 6, 7, 8 and 9), temperature (30, 37 and $40^{\circ}C$) and rotational speed (150, 200 and 250 rpm) on the growth and the hepatitis B core antigen (HBcAg) production of Escherichia coli W3110IQ were examined in the present Study. The highest growth rate is achieved at pH 7, $37^{\circ}C$ and at a rotational Speed of 250 rpm which is 0.927 $h^{-1}$. The effect of pH on cell growth is more substantial compared to other parameters; it recorded a $123\%$ different between the highest growth rate (0.927 $h^{-1}$) at pH 7 and lowest growth at pH 5. The highest protein yield is achieved at pH 9, rotational speed of 250 rpm and $40^{\circ}C$. The yield of protein at pH 7 is $154\%$ higher compared to the lowest yield achieved at pH 5. There is about $28\%$ different of the protein yield for the E. coli cultivated at 250 rpm compared to that at 150 rpm which has the lowest HBcAg yield. The yield of protein at $40^{\circ}C$ is $38\%$ higher compared to the lowest yield achieved at $30^{\circ}C$.

• The Korean Journal of Physiology and Pharmacology
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• 제7권3호
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• pp.125-130
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• 2003

The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine the effect of chlorhexidine digluconate on differential rotational mobility of different positions of the number of membrane bilayer phospholipid carbon atoms. The six membrane components differed with respect to 2, 3, 6, 9, 12, and 16-(9-anthroyloxy)stearic acid (2-AS, 3-AS, 6-AS, 9-AS, 12-AS and 16-AP) probes, indicating different membrane fluidity. Chlorhexidine digluconate increased the rate of rotational mobility of hydrocarbon interior of the cultured Porphyromonas gingivalis outer membranes (OPG) in a dose-dependent manner, but decreased the mobility of surface region (membrane interface) of the OPG. Disordering or ordering effects of chlorhexidine digluconate on membrane lipids may be responsible for some, but not all of its bacteriostatic and bactericidal actions.

• 천문학회보
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• 제39권1호
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• pp.66.2-66.2
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• 2014

We carried out photometric observations of Maria family asteroids during 134 nights spanning from July 2008 to May 2013, and derived synodic rotational periods for 51 objects including obtained periods of 34 asteroids for the first time. In this study, we found that there is a significant excess of fast and slow rotators. The one-sample Kolmogorov-Smirnov test confirms that the spin rate distribution is not consistent with the Maxwellian at a 92% confidence level. From the correlations between rotational period, amplitude of lightcurve, and size, we conclude that rotational properties of Maria family have been changed considerably by the non-gravitational force such as the Yarkovsky and the YORP effect. Using the lightcurve inversion method, we successfully determined the pole orientation for the 13 Maria members, and found the excess of prograde objects versus retrograde with a ratio ($N_p/N_r$) of 3. This implies that retrograde rotators could have been ejected by the 3:1 resonance to the inner Solar System since the generation of Maria family. We estimate that approximately 37 - 75 kilometer-sized Maria asteroids have entered to near-Earth space every 100 Myr.

• 대한족부족관절학회지
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• 제18권3호
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• pp.119-123
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• 2014

Purpose: This study was designed to evaluate the clinical efficacy of temporary K-wire fixation in F-plate fixation for displaced intra-articular calcaneal fractures. Materials and Methods: Two groups (group 1 with F-plate fixation only and group 2 with temporary K-wire fixation and F-plate fixation) of patients were included in this study. The temporary K-wire was removed six weeks after the operation. Each group consisted of 33 cases. Rotational axis angles were measured radiographically and the foot and ankle outcome score (FAOS) was used for clinical assessment. Results: In group 1, the mean rotational axis angle was reduced from $27^{\circ}$ preoperatively to $5.59^{\circ}$ postoperatively and the angle at last follow-up was $9.94^{\circ}$. There was an increase in angle of $4.35^{\circ}$ between postoperative and the last follow-up measurement. In group 2, the mean rotational axis angle was reduced from $21.2^{\circ}$ preoperatively to $4.39^{\circ}$ postoperatively and the angle at last follow-up was $5.91^{\circ}$. There was an increase in angle of $1.52^{\circ}$ between postoperative and the last follow-up measurement. Significant difference in the changes of rotational axis angle was observed between the two groups. However, no significant difference in FAOS was observed between the two groups. Conclusion: Temporary K-wire fixation can prevent reduction loss when treating displaced intra-articular calcaneal fractures with an F-plate.

• 한국산학기술학회논문지
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• 제14권3호
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• pp.1252-1257
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• 2013

본 연구는 Homomixer의 회전속도에 따른 염화마그네슘 유화물의 제조특성을 비교하여 두부응고제로서 염화마그네슘유화물의 제조상 최적조건을 확립하기로 하였다. 염화마그네슘유화물의 입자는 Homomixer의 회전속도가 증가할수록 미세화 되었다. 입자크기는 $1{\sim}5{\mu}m$로 분포하고 있었다. 분산상의 입자크기가 미세화 할수록 점도의 증가와 보관 중 유상분리의 지연으로 상관관계가 있음을 나타내었다. 따라서 염화마그네슘유화물을 제조하는데 있어서 Homomixer의 회전속도는 10,000rpm 이상에서 제조하는 것이 두부응고제로서 두부의 조직 상태와 이수율 등이 가장 좋은 결과를 나타내었다.

• Structural Engineering and Mechanics
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• 제68권5호
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• pp.563-573
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• 2018

Temperature-induced responses, such as strains and displacements, are related to the boundary conditions. Therefore, it is required to determine the boundary conditions to establish a reliable bridge model for temperature-induced responses analysis. Particularly, bridge bearings usually present nonlinear behavior with an increase in load, and the nonlinear boundary conditions cause significant effect on temperature-induced responses. In this paper, the bridge nonlinear boundary conditions were simulated as bilinear translational or rotational springs, and the boundary parameters of the bilinear springs were identified based on the measured temperature-induced responses. First of all, the temperature-induced responses of a simply support beam with nonlinear translational and rotational springs subjected to various temperature loads were analyzed. The simulated temperature-induced strains and displacements were assumed as measured data. To identify the nonlinear translational and rotational boundary parameters of the bridge, the objective function based on the temperature-induced responses is then created, and the nonlinear boundary parameters were further identified by using the nonlinear least squares optimization algorithm. Then, a beam structure with nonlinear translational and rotational springs was simulated as a numerical example, and the nonlinear boundary parameters were identified based on the proposed method. The numerical results show that the proposed method can effectively identify the parameters of the nonlinear boundary conditions. Finally, the boundary parameters of a real arch bridge were identified based on the measured strain data and the proposed method. Since the bearings of the real bridge do not perform nonlinear behavior, only the linear boundary parameters of the bridge model were identified. Based on the bridge model and the identified boundary conditions, the temperature-induced strains were recalculated to compare with the measured strain data. The recalculated temperature-induced strains are in a good agreement with the real measured data.

• 한국항공우주학회지
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• 제46권11호
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• pp.921-933
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• 2018

관성항법장치 순수항법 성능을 개선하는 방법으로 관성센서 오차가 상호 상쇄되도록 관성센서뭉치를 회전시켜 항법 성능을 개선하는 방법이 있으며 이러한 원리로 동작하는 항법장치를 회전형 관성항법장치라 한다. 관성센서 오차에 의한 회전형 관성항법장치의 정확한 항법 성능 분석을 위해서는 이에 대한 이론적 오차해석이 요구되나 기존의 많은 연구에서는 지구회전 각속도 및 중력 가속도에 의한 영향을 무시하고 오차해석을 수행하여 회전형 관성항법장치의 정확한 항법 성능 분석이 수행되지 않았다. 본 논문에서는 링레이저 자이로 기반 회전형 관성항법장치의 정확한 항법 성능 분석을 위하여 지구회전 각속도 및 중력 가속도 항을 포함한 이론적인 오차해석을 수행하고 이를 기반으로 회전형 관성항법장치의 항법 성능 분석 결과를 제시하였다.

• 센서학회지
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• 제21권6호
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• pp.440-445
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• 2012

Contact-type Linear Encoder-like Capacitive Displacement Sensor (CLECDiS) is a novel displacement sensor which has wide measurable range with high resolution. The sensor, however, is very sensitive to relative rotational alignment between stator and mover of the sensor as well as its displacement. In addition to, there can be some disturbances in the relative rotational alignment, so some noises occur in the sensor's output signal by the disturbances. This negative effect of the high sensitivity may become larger as increasing sensitivity. Therefore, this negative effect of the high sensitivity has to be compensated and reduced to achieve nanometer resolution of the sensor. In this study, a new type capacitive linear encoder with a mechanical guide is presented to reduce the relative rotational alignment problem. The presented method is not only to reduce the alignment problem, but also to assemble the sensor to the stage conveniently. The method is based on a new type CLECDiS that has mechanical guide autonomously. In the presented sensor, when the device is fabricated by micro-machining, the guide-rail is also fabricated on the surface of the sensor. By the direct fabrication of the guide-rail with high precision micro-machining, errors of the guide-rail can be reduced significantly. In addition, a manual yaw alignment is not required to obtain large magnitude of the output signal after the assembly of the sensor and the stage. The sensor movement is going to follow the guide-rail automatically. The prototype sensor was fabricated using the presented method, and we verify the feasibility experimentally.