• Clinical and Experimental Pediatrics
• /
• v.59 no.11
• /
• pp.432-439
• /
• 2016

Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental risk factor for the development of childhood asthma. Respiratory viral infections have also been recognized as the most common cause of asthma exacerbation. The advent of molecular diagnostics to detect respiratory viruses has provided new insights into the role of human rhinovirus (HRV) infections in the pathogenesis of asthma. However, it is still unclear whether HRV infections cause asthma or if wheezing with HRV infection is simply a predictor of childhood asthma. Recent clinical and experimental studies have identified plausible pathways by which HRV infection could cause asthma, particularly in a susceptible host, and exacerbate disease. Airway epithelial cells, the primary site of infection and replication of HRV, play a key role in these processes. Details regarding the role of genetic factors, including ORMDL3, are beginning to emerge. This review discusses recent clinical and experimental evidence for the role of HRV infection in the development and exacerbation of childhood asthma and the potential underlying mechanisms that have been proposed.

• Journal of the Korea Safety Management & Science
• /
• v.16 no.1
• /
• pp.89-99
• /
• 2014

This paper reviewed the relationship between job demands/resources and safety compliance, and the mediating effect of job burnout. Based on the responses from 247 employees, the results of multiple regression analysis appeared as follow; 1) two demands factors(role ambiguity and role overload) effect positively on safety compliance. 2) job resources factors(autonomy and social support) effect negatively on safety compliance. 3) job burnout effects negatively on safety compliance. 4) job burnout mediates between 4 job demands/resources(role ambiguity and role overload, autonomy, social support) and safety compliance.

• The Journal of Fisheries Business Administration
• /
• v.40 no.3
• /
• pp.127-146
• /
• 2009

This study is to estimate the factor weights of the reasons for decreases in marine fishery resources using the Analytical Hierarchy Process. Furthermore, it classifies 20 fishes under a fishery resource recovery plan into various groups of fishes according to these factor weights using the non-hierarchial cluster analysis. The factors of decreases in marine fishery resources are identified as bio-ecological, technology-system, economic-business, and fishing village-society factors. Two of the most important factors of decreases in resource are turned out to be the economic-business and bio-ecological factors, estimated as 31% and 30% respectively. The technology-system and fishing village-society factors are estimated as 21% and 18% respectively. The study utilizes non-hierarchical cluster analysis in order to classify 20 fishes into 2, 3, and 4 groups. K-means cluster analysis is applied for grouping in conjunction with ANOVA to identify statistical differences in factors. Once again, the economic-business and bio-economic factors play main role in grouping 2-groups of fishes case. The third group of fishes in addition to the previous 2 groups of fishes appears as those 4 factors of decrease evenly play about the same role at a 3-groups of fishes case. Finally, the economic-business and bio-economic factors are turned out to be evenly important in the 4th group once there are 4-groups of fishes.

• Journal of Korean Foot and Ankle Society
• /
• v.11 no.2
• /
• pp.141-144
• /
• 2007

Purpose: To statistically evaluate the contributing role of the 3 radiographic factors (Obliquity, Asymmetry, Joint deviation) of the hallux valgus interphalangeus with comparison to the normal control group. Materials and Methods: The study is based on the standing foot AP radiographs of the 77 feet (56 patients) of the hallux valgus interphalangeus out of 119 feet of randomly sampled patients of the age range 20 to 60. Fractures or other foot disorders have been excluded. Obliquity, asymmetry and joint deviation factors formed by proximal and distal phalanges of hallux are measured by one observer and evaluated the statistical significance of the contribution of the 3 factors to the hallux interphalangeal angle (HIA). Results: The average age of the patients were 36.0 years old and average HIA was $14.5^{\circ}{\pm}2.8^{\circ}$. Obliquity was measured $4.8^{\circ}{\pm}2.90^{\circ}$, asymmetry $8.2^{\circ}{\pm}3.28^{\circ}$ and joint deviation $2.0^{\circ}{\pm}1.85^{\circ}$. All 3 factors showed the statistical significance as the contributing factors to the HIA and among them, the asymmetry played the biggest role (p<0.05). Conclusion: Hallux interphalangeal angle is formed by 3 radiographic factors (Obliquity, Asymmetry, Joint deviation), and among them the asymmetry factor plays the biggest role.

• Asian-Australasian Journal of Animal Sciences
• /
• v.29 no.8
• /
• pp.1065-1074
• /
• 2016

Growth factors play an important role during early ovarian development and folliculogenesis, since they regulate the migration of germ cells to the gonadal ridge. They also act on follicle recruitment, proliferation/atresia of granulosa cells and theca, steroidogenesis, oocyte maturation, ovulation and luteinization. Among the growth factors, the growth differentiation factor 9 (GDF9) and the bone morphogenetic protein 15 (BMP15), belong to the transforming growth factor beta (TGF-${\beta}$) superfamily, have been implicated as essential for follicular development. The GDF9 and BMP15 participate in the evolution of the primordial follicle to primary follicle and play an important role in the later stages of follicular development and maturation, increasing the steroidogenic acute regulatory protein expression, plasminogen activator and luteinizing hormone receptor (LHR). These factors are also involved in the interconnections between the oocyte and surrounding cumulus cells, where they regulate absorption of amino acids, glycolysis and biosynthesis of cholesterol cumulus cells. Even though the mode of action has not been fully established, in vitro observations indicate that the factors GDF9 and BMP15 stimulate the growth of ovarian follicles and proliferation of cumulus cells through the induction of mitosis in cells and granulosa and theca expression of genes linked to follicular maturation. Thus, seeking greater understanding of the action of these growth factors on the development of oocytes, the role of GDF9 and BMP15 in ovarian function is summarized in this brief review.

• The Journal of the Korea Contents Association
• /
• v.15 no.2
• /
• pp.419-432
• /
• 2015

This study analyzed the moderating role of the suitability factors of corporate strategies and information system strategies targeting small and medium sized transportation companies in Korea. The analytical result has found that the suitable factors of corporate strategies and information system strategies play the moderating role in the ERP introduction factors and internal performance. In other words, the suitability factors of corporate strategies and information system strategies were analyzed to play the moderating role in support of CEOs, education/training, users' IT capabilities, standardization/formulation of business, infrastructure of information technologies, and internal performance. The result of this study based on the above analytical results has found that introduction performance will be maximized when ERP packages are introduced in the small and medium-sized transportation companies and corporate strategies properly harmonize with the introduction strategies of ERP packages in the companies.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.23 no.3
• /
• pp.290-299
• /
• 2017

Purpose: The purpose of this study is to investigate nurses' role conflict and intention to remain and to identify factors that may influence this intention. Methods: Data were collected from 172 nurses in a 600-plus bed hospital on nurses' intention to remain, which included 47 items and nurses' role conflict, which included 82 items from a self-reported questionnaire. Data were analyzed by descriptive statistics and stepwise multiple regression using SPSS 22.0 Results: The mean of the role conflict frequency was 2.71(${\pm}.39$) and the mean severity was 2.86 (${\pm}.47$). The most significant item among the items of intention to remain was "a nurse's job is to help people." The intention to remain employed showed a significant difference in the duration of desired working period and subjective job satisfaction. The subjective job satisfaction of nurses was the most influential variable as a factor affecting the intention to remain, followed by frequency of role conflict in nursing practice. Conclusion: These results suggest that inadequate nursing environments in nursing practice require improvement and support the idea that nurses with positive attitudes of the nursing organization and theirs leaders reduce nurses' related fatigue.

• The Journal of the Korea Contents Association
• /
• v.6 no.2
• /
• pp.127-135
• /
• 2006

The object of this study is to improve the police administration service and the work performance of police officers, through the analytic ground to increase job satisfaction and to solve the role conflict by setting the role conflict as a main factor among many factors to influence the job satisfaction between the role conflict and the job satisfaction of police officers and explaining the factors of the role conflict.

• Journal of the Korean Home Economics Association
• /
• v.31 no.4
• /
• pp.141-155
• /
• 1993

The purpose of this study is to investigate Korean youth's motivations for parenthood and concepts of parental role and to examine closely the relationship with the sociodemographic variables(age, sex, religious orientation, growth region, father's occupational level, parental education degree). the subjects are 465 students of the three universities in National Capital region. The data are collected by questionnair methods and analyzed by t-test, F-test, factor analysis. The major findings are as follows: 1) The motivations for parenthood are classified into five factors. These are acquisition of social status factor, continuation of self factor, achevement and creativity factor, tradition factor, primary group ties factor. The korean youth think the most of achievement and creativity factor among five motivation factors. 2) The korean students have somewhat stereo-typed concepts of parental role and place the stress on training the behaviors of the child and encouraging the development of the child. 3) The sociodemographic variables to have relationship with the motivations for parenthood are age, sex, growth region and father and mother's educational degrees. And the variables related with the concepts of parental role are sex, father's occupational level. 4) There are relationships between traditional role concepts of a father and motivation of acquisition of social status factor and tradition factor. And traditional role concepts of a mother are related with motivations of acquisition of social status factor and primary group ties factor among the motivations for parenthood.

• The Journal of Korean Society for School & Community Health Education
• /
• v.22 no.3
• /
• pp.41-54
• /
• 2021

Objectives: This study aimed to confirm the degree of gender sensitivity, gender role conflict, nursing professionalism of nursing students and the factors that affect nursing professionalism. Methods: During Jan. 19 to Feb. 5 in 2021, the structured questionnaire was used for 187 nursing students by on-line research methods. Data were analyzed by descriptive analysis, mean comparison(t-test, ANOVA), correlation analysis(Pearson's correlation coefficient) and multiple regression using SPSS/WIN 25.0. Results: The gender sensitivity had positive relationship with nursing professionalism, and gender role conflict had negative relationship with nursing professionalism. And the prediction factors influencing nursing professionalism were major satisfaction, gender sensitivity and gender role conflict. The total variance was 8.2% by predictors. Conclusions: In order to improve the nursing professionalism of nursing students, various ways to increase the satisfaction level of major should be sought, and program should be prepared to improve gender sensitivity and reduce gender role conflict.