• Title/Summary/Keyword: Risk-benefit

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Treatment of Mycobacterium avium Complex Pulmonary Disease

  • Kwon, Yong-Soo;Koh, Won-Jung;Daley, Charles L.
    • Tuberculosis and Respiratory Diseases
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    • v.82 no.1
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    • pp.15-26
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    • 2019
  • The pathogen Mycobacterium avium complex (MAC) is the most common cause of nontuberculous mycobacterial pulmonary disease worldwide. The decision to initiate long-term antibiotic treatment is difficult for the physician due to inconsistent disease progression and adverse effects associated with the antibiotic treatment. The prognostic factors for the progression of MAC pulmonary disease are low body mass index, poor nutritional status, presence of cavitary lesion(s), extensive disease, and a positive acid-fast bacilli smear. A regimen consisting of macrolides (clarithromycin or azithromycin) with rifampin and ethambutol has been recommended; this regimen significantly improves the treatment of MAC pulmonary disease and should be maintained for at least 12 months after negative sputum culture conversion. However, the rates of default and disease recurrence after treatment completion are still high. Moreover, treatment failure or macrolide resistance can occur, although in some refractory cases, surgical lung resection can improve treatment outcomes. However, surgical resection should be carefully performed in a well-equipped center and be based on a rigorous risk-benefit analysis in a multidisciplinary setting. New therapies, including clofazimine, inhaled amikacin, and bedaquiline, have shown promising results for the treatment of MAC pulmonary disease, especially in patients with treatment failure or macrolide-resistant MAC pulmonary disease. However, further evidence of the efficacy and safety of these new treatment regimens is needed. Also, a new consensus is needed for treatment outcome definitions as widespread use of these definitions could increase the quality of evidence for the treatment of MAC pulmonary disease.

A Conceptual Design and Feasibility Analysis of a Window Cleaning Device (유리창 청소장치의 개념 디자인 및 경제적 타당성 예측)

  • Kim, Kyoon-Tai;Jun, Young-Hun
    • Journal of the Korea Institute of Building Construction
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    • v.20 no.6
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    • pp.537-543
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    • 2020
  • The window cleaning works are manpower-dependent and are performed in an unstable posture at high altitude, so that there is a risk of falling. Therefore, there is an urgent need to improve the safety of workers. In this study, a conceptual design was proposed for the cleaning of exterior windows of a building, and the economic feasibility of the proposed conceptual model was analyzed. The proposed model is designed to avoid protrusions such as window frames, and to be able to respond even if the shapes of the upper and lower parts are different. As a result of analyzing the economic feasibility of the designed conceptual model, the benefit cost ratio was 4.48, which was significantly higher than 1. Therefore, the economic feasibility of the proposed window cleaning device is expected to be sufficient. The results analyzed in this paper will be used in the development and marketing of the window cleaning device.

Cone-beam computed tomography artifacts in the presence of dental implants and associated factors: An integrative review

  • Terrabuio, Bianca Rodrigues;Carvalho, Caroline Gomes;Peralta-Mamani, Mariela;da Silva Santos, Paulo Sergio;Rubira-Bullen, Izabel Regina Fischer;Rubira, Cassia Maria Fischer
    • Imaging Science in Dentistry
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    • v.51 no.2
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    • pp.93-106
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    • 2021
  • Purpose: This study was conducted to review the literature regarding the types of cone-beam computed tomography (CBCT) artifacts around dental implants and the factors that influence their formation. Materials and Methods: A search strategy was carried out in the PubMed, Embase, and Scopus databases to identify published between 2010 and 2020, and 9 studies were selected. The implants included 306 titanium, titanium-zirconium, and zirconia implants, as well as 5 titanium cylinders. Results: The artifacts around the implants were the beam-hardening artifact, the streaking artifact, and band-like radiolucent areas. Some factors that influenced the formation of artifacts were the implant material, bone type, evaluated regions, distance, type of CBCT, field of view (FOV) size, milliamperage, peak kilovoltage (kVp), and voxel size. The beam-hardening artifact was the most widely reported, and it was minimized in protocols with a smaller FOV, larger voxels, and higher kVp. Conclusion: The risk and benefit of these protocols in individuals with dental implants must be considered, and clinical examinations and complementary radiographs play an essential role in implantology.

Perfecting the System for Assessment of the Financial Potential of a Transport Enterprise

  • Nesterov, Evgeny Aleksandrovich;Borisov, Andrei Viktorovich;Shadskaja, Irina Gennadievna;Shelygov, Aleksandr Vladimirovich;Sharonin, Pavel Nikolaevich;Frolov, Alexander Lvovich;Lebedeva, Olga Yevgenievna
    • International Journal of Computer Science & Network Security
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    • v.22 no.7
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    • pp.109-116
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    • 2022
  • The article is devoted to perfecting the system of management of the financial potential of transport enterprises. It is established that transport as an integral part of the state economy has to organically enter the market economy and provide sustainable transport services to national economy enterprises regardless of ownership, as well as ensure passenger transportation. It is also determined that in the conditions of market relations, transport highways must perform their functions with sufficient economic benefit to keep their material and technical resources in good order, conduct an investment policy with extensive use of scientific and technological progress, as well as a social policy guaranteeing the conditions for employees' motivated work. The study reveals an association between the financial and strategic goals of transport enterprises and the minimization of their economic risks, the prevention of bankruptcy and profit margin shortfalls. It is found that transport enterprises need to strive for the overall improvement of their financial potential through increasing the components of financial potential and assessing the impact of risk factors on them: the capacity of fixed assets, the capacity of financial resources, the capacity of services, and the capacity of credit opportunities. These are the elements of transport enterprises' financial potential that ensure its desired level. It is demonstrated that of critical importance in managing the financial potential of a transport enterprise is the role of financial resources, as a subject cannot reach the desired strategic goals without them.

Trends and Prospective of Environmental Health Research through SWOT Analysis (SWOT 분석을 통한 환경보건 연구의 동향과 전망 고찰)

  • Shin, Jihun;Ra, Jin-Sung;Kim, Ki-Tae;Lee, Jongdae;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.48 no.5
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    • pp.255-265
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    • 2022
  • Background: Research in environmental health (EH) is of crucial strategic importance for contemporary society. It is becoming even more critical in light of the increasingly rapid pace of environmental changes, opportunities, and threats. Objectives: This study aimed to identify trends and the prospective of environmental health research using SWOT analysis. Methods: The trends in environmental health research were reviewed in previous studies and reports. Reviewed manuscripts were searched for using the keywords of 'environmental health' and 'environmental hygiene' in the KCI (Korean Journal of Citation Index), KISS (Korean Academic Information), PubMed, and Google Scholar. Results: It is essential to center the EH research agenda around key priorities focusing on technological innovation, job creation, and the increasingly prominent role of the private sector. Given the rapidly evolving global sustainability agenda, greater clarity on the ever-increasing sources of complexity and growing expectations of the public might be needed. This requires the identification of criteria to identify EH research priorities with the ultimate goal of maximizing societal benefit. Public health relevance, such as extent and severity of health impact, level of exposure, and inequalities of effects, could be included. Conclusions: Considering the recent interest in and importance of environmental health, a comprehensive approach to environmental health research should be required through the application of the latest science and technology, citizen participation, and environmental health surveillance systems.

A Study on the Privacy Paradox in the IoT-based Smart Home Camera Usage Environment: Focusing on a Comparative Study of User Experience (IoT 기반 스마트 홈카메라 이용환경에서의 프라이버시 패러독스 현상에 관한 연구: 사용경험 비교연구를 중심으로)

  • Lyu, JinDan;Kwon, Sundong
    • Journal of Information Technology Applications and Management
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    • v.28 no.6
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    • pp.145-161
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    • 2021
  • Recently, as personal information utilization devices such as IoT, artificial intelligence, and wearable devices that focus on the individual have spread, privacy violations are also increasing. However, the privacy paradox of providing personal information to enjoy services while worrying is getting stronger. However, there are still preliminary studies on this. In this study, an intelligent home camera based on IoT technology was selected as a research object, and whether privacy paradox exists in the IoT environment, including smart home camera, was studied. To this end, the effect of perceived usefulness, a benefit factor of smart home camera use, and privacy concern, a risk factor, on intention to use was verified. In addition, it was investigated whether the relationship between privacy concerns and intention to use differs according to the presence or absence of use experience. In order to verify the research model, a survey was conducted with people with and without experience in using smart home cameras, and a total of 298 data samples were used for statistical analysis. As a result of the analysis, it was found that both perceived usefulness and privacy concerns had a positive effect on the intention to use, proving that privacy paradox exists in the IoT-based smart home camera environment. In addition, by analyzing the fact that privacy concerns have different effects on usage intentions depending on the user experience, it was verified that those with experience have a strong privacy paradox and those without experience have a weak privacy paradox. This study is meaningful because it seeks strategic implications to improve service and business performance by understanding the relationship between privacy attitudes and behaviors of IoT service providers, including smart home cameras.

Avian influenza virus surveillance in wild bird in South Korea from 2019 to 2022

  • Eun-Jee, Na;Su-Beom, Chae;Jun-Soo, Park;Yoon-Ji, Kim;Young-Sik, Kim;Jae-Ku, Oem
    • Korean Journal of Veterinary Service
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    • v.45 no.4
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    • pp.285-292
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    • 2022
  • Avian influenza viruses (AIVs) cause contagious diseases and have the potential to infect not only birds but also mammals. Wild birds are the natural reservoir of AIVs and spread them worldwide while migrating. Here we collected active AIV surveillance data from wild bird habitats during the 2019 to 2022 winter seasons (from September to March of the following year) in South Korea. We isolated 97 AIVs from a total of 7,590 fecal samples and found the yearly prevalence of AIVs was 0.83, 1.48, and 1.27, respectively. The prevalence of AIVs were generally higher from September to November. These findings demonstrate that a high number of wild birds that carry AIVs migrate into South Korea during the autumn season. The highest virus numbers were isolated from the species Anas platyrhynchos (72%; n=70), followed by Anas poecilorhyncha (15.4%; n=15), suggesting that each is an important host for these pathogens. Twenty-five hemagglutinin-neuraminidase subtypes were isolated, and all AIVs except the H5N8 subtype were found to be low-pathogenic avian influenza viruses (LPAIVs). Active surveillance of AIVs in wild birds could benefit public health because it could help to estimate their risk for introduction into animals and humans. Moreover, considering that 132 cases of human AIV infections have been reported worldwide within the last 5 years, active surveillance of AIVs is necessary to avoid outbreaks.

Domestic polysomnography operation status and problem analysis -Focusing on the characteristics of each type of medical institution- (국내 수면다원검사 운영현황 및 문제점 분석 -의료기관 유형별 특징을 중심으로-)

  • YU, TAE GYU
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.443-448
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    • 2023
  • Over the past five years, the number of patients with sleep disorders has increased by about 250,000 from 840,000 in 2017 to 1.09 million in 2021. In addition, sleep disorder is a factor that causes dementia risk factors, and furthermore, the population with sleep disorder is a very important policy issue in terms of stable health insurance financial management in the future in terms of national health management in the super-aging trend. Therefore, this study aims to establish an efficient treatment environment in medical institutions responsible for the current status of polysomnography and effective reimbursement policies for the recently increasing population with sleep disorders, and appropriate sleep management policies for future sleep disorders through correct implementation. We are trying to find out the actual condition and improvement plan through interviews with related organizations and experts.

Long-Term Management of Seizures after Surgical Treatment of Supratentorial Cavernous Malformations : A Retrospective Single Centre Study

  • Dziedzic, Tomasz A.;Koczyk, Kacper;Nowak, Arkadiusz;Maj, Edyta;Marchel, Andrzej
    • Journal of Korean Neurosurgical Society
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    • v.65 no.3
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    • pp.415-421
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    • 2022
  • Objective : Seizure recurrence after the first-ever seizure in patients with a supratentorial cerebral cavernous malformation (CCM) is almost certain, so the diagnosis and treatment of epilepsy is justified. The optimal method of management of these patients is still a matter of debate. The aim of our study was to identify factors associated with postoperative seizure control and assess the surgical morbidity rate. Methods : We retrospectively analysed 45 consecutive patients with a supratentorial CCM and symptomatic epilepsy in a single centre. Pre- and postoperative epidemiological data, seizure-related patient histories, neuroimaging results, surgery details and outcomes were obtained from hospital medical records. Seizure outcomes were assessed at least 12 months after surgery. Results : Thirty-five patients (77.8%) were seizure free at the long-term follow-up (Engel class I); six (13,3%) had rare, nocturnal seizures (Engel class II); and four (8.9%) showed meaningful improvement (Engel class III). In 15 patients (33%) in the Engel I group; it was possible to discontinue antiepileptic medication. Although there was not statistical significance, our results suggest that patients can benefit from early surgery. No deaths occurred in our study, and mild postoperative neurologic deficits were observed in two patients (4%) at the long-term follow-up. Conclusion : Surgical resection of CCMs should be considered in all patients with a supratentorial malformation and epilepsy due to the favourable surgical results in terms of the epileptic seizure control rate and low postoperative morbidity risk, despite the use of different predictors for the seizure outcome.

The Effect of Perceived Overqualification on Loyalty through Benefits and Risks of Workers (지각된 과잉자격이 직장인의 혜택과 위험을 통해충성도에 미치는 영향)

  • Noh Hyeyoung;Lee Sin-Bok
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.2
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    • pp.339-348
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    • 2023
  • Uncertainty in the employment market from the COVID-19 created incomplete employment. As a result, job seekers were required to have overqualifications than job requirements. In previous studies, overqualified workers by incomplete employment were not satisfied with their jobs. A representative result is the intention to change jobs. However, within COVID-19, the perceived overqualification of workers will appear differently. This is because in a rapidly increased employment competition environment due to COVID-19, it will appear as loyalty to maintain a stable job. As a result of this study, work experience was the greatest benefit and high risk for office workers. In addition, both the benefits and risks of overqualification affected loyalty. Unlike the negative impact as in previous studies, workers tried to remain stable at work in an unstable employment environment caused by COVID-19.