• Journal of Soil and Groundwater Environment
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• v.23 no.6
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• pp.54-72
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• 2018

This study reviewed standard operation procedures for fractionation and analytical methods of total petroleum hydrocarbons (TPH) in north america and european countries to aid proper establishment of risk assessment protocols associated with TPH exposure in Korea. In current, the TPH fraction methods established by Massachusetts Department of Environmental Protection (MassDEP) and Total Petroleum Hydrocarbon Criteria Working Group (TPHCWG) are most frequently employed worldwide. Both methods were developed on the basis of direct exposure of TPH from soil, although the method by TPHCWG also took into account the mobility of TPH. Volatile and extractable fractions of petroleum hydrocarbons were analyzed either separately or together. TPH fractionation methods were evaluated based on conservative toxicity values considering the uncertainty of risk assessment in light of current standard protocol for analyzing soil contaminants in Korea, and it was concluded that the method developed by MassDEP is more appropriate.

• Toxicological Research
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• v.35 no.2
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• pp.131-136
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• 2019

Ethylhexyl dimethyl para-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl dimethyl PABA is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5-2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that ethylhexyl dimethyl PABA is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that ethylhexyl dimethyl PABA inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of ethylhexyl dimethyl PABA following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of ethylhexyl dimethyl PABA in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% ethylhexyl dimethyl PABA, which is the maximum level allowed by the relevant domestic authorities.

• Journal of the Society of Disaster Information
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• v.18 no.4
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• pp.873-882
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• 2022

Purpose: The purpose of this paper is to analyze accidents and potential risks occurring at container terminals and to conduct on safety management plans tailored to container terminals. Method: A model for establishing a safety management plan is presented through a case study of container terminal risk assessment and literature analysis. Result: According to the 'Statistics of Accidents in the Harbor Handling Industry', 2,800 people were killed or injured during port work for 10 years from 2011 to 2021. This corresponds to an occupational accident rate of one person every 1.5 days. As a method of improving these accidents and disasters, a highly effective safety management plan should be established to prevent the recurrence of accidents in accordance with the Special Act on Port Safety. It is proposed to establish a safety management plan that reflects the risk assessment of container terminals, safety organization, safety budget, safety rules, and safety education.

• Journal of Environmental Impact Assessment
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• v.24 no.6
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• pp.549-560
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• 2015

The priorities of siting restriction was derived from quantification of environmental hazard according to industrial classification based on 'Chemical Ranking and Scoring System(CRS)' which is handling the discharge characteristics of 31 industrial classifications regulated from locating at 'Industrial Complex in Rural Area(ICRA)'. CRS that is utilizing the data of 'Pollutant Release and Transfer Registers(PRTR)' is applied to determine human health risk and ecological risk which are calculated by discharged amount and materials $LC_{50}$ according to water, soil and air media based on industrial classification. From this process, exposure assessment and toxicity assessment for integrating the adverse environmental impact and the mitigation effect of environmental risk according to the development of environmental technologies into establishing the rational landuse management method for the 31 industrial classifications regulated from locating at ICRA was analyzed. From the assessment result of the siting restriction removal at ICRA for 31 industrial classifications, based on 2012 year reference 6 industries that includes Manufacture of Guilt Coloration Surface Processing Steel Materials, Manufacture of Biological Product, Manufacture of Smelting Refining and Alloys of Copper, Dyeing and Finishing of Fibers and Yarns, Manufacture of Other Basic Iron and Steel n.e.c., Rolling Drawing and Extruding of Non-ferrous Metals n.e.c. are calculated as having relatively lower environmental hazards, thus it is judged that the siting restriction mitigation at ICRA is possible for the 6 industrial classifications that are not discharging the specific hazardous water contaminants during manufacturing process.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.2
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• pp.54-61
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• 2016

Studies on assessment tools for predicting cardiovascular disease risk (CDR), along with the studies to prevent CDR have been consistently reported. The validity of the Framingham risk score (FRS), a commonly known tool, has been verified through the precedent studies. In this study, we examined the differences of FRS according to the application of categories of LDL cholesterol (LDL-C) or Total cholesterol (TC), and attempted to evaluate the agreement of 10 yr CHD risk judgment based on the above-mentioned application. Excluding those diagnosed as cardiovascular diseases, data on subjects (755 men and 775 women) from the 2011 Korean National Health and Nutrition Examination Survey were used. We found differences of FRS and 10 yr CHD risk depending on the application of categories of LDL cholesterol (LDL-C) or Total cholesterol (TC). FRS of TC points were higher than those of LDL-C in both men and women. In classification of low risk (<10%), intermediate risk (10~19%), and high risk (${\geq}20%$), there were disagreements for 106 men and 26 women. Women showed almost perfect agreement from Coefficient of Cohen's Kappa (0.718 in men, and 0.884 in women). In assessment of 10 yr CHD risk, R-squared value from regression including TC was higher than that of LDC-C in both men and women (0.972 vs 0.885). From this result, we can draw a conclusion that correlation coefficients of FRS and CHD risk including TC were higher than those of LDC-C, and women showed a greater degree of agreement than men.

• Toxicological Research
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• v.19 no.4
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• pp.297-301
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• 2003

To investigate biomarker-based exposure to phthalates and related factors with demographics, 100 subjects who had participated in comprehensive health check-up were selected. We collected demographics through questionnaires and analyzed urine samples for 5 phthalates. Statistical likelihoods and regression methods were applied for data analysis using censored data. The highest levels of urine phthalates were 216$\mu\textrm{g}$/ml in di-isodecyl phthalate, 29.0$\mu\textrm{g}$/ml in di-butyl phthalate, 5.78$\mu\textrm{g}$/ml in di-(2-ethylhexyl) phthalate. The median values of di-(2-ethylhexyl) phthalate were 0.2340 $\mu\textrm{g}$/ml for male smokers, 0.0399 $\mu\textrm{g}$/ml for male non-smokers and 0.0085 $\mu\textrm{g}$/ml for female non-smokers, respectively. Di-(2-ethylhexyl) phthalate, benzyl butyl phthalate and di-isodecyl phthalate were higher in males than in females. In addition, mono-2-ethylhexyl phthalate was decreased with age. Our findings suggest that there might be significant demographic variations in exposure and/or metabolism of phthalates, and that health-risk assessment for phthalate exposure in humans should consider different potential risk groups.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.181-181
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• 2023

Flood is a major threat to human society, and scientific assessment of flood risk in human living areas is an important task. In this study, two different methods were used to evaluate the flood in Ulsan City, and the results were comprehensively compared and analyzed. Based on the fuzzy mathematics and VIKOR method of the multi-objective decision system, similar evaluation results were obtained in the study area. The results show that due to the large number of rivers in Ulsan City and the relatively high exposure index, the whole city faces a high risk of flooding. However, fuzzy mathematics theory pays more attention to the negative impact of floods on people, and the adaptability in the Nam-gu District is lower. In contrast, the VIKOR method pays more attention to the positive role of the economy and population in flood protection, and thus obtains a higher score. Both approaches demonstrate that the city of Ulsan faces a high risk of flooding and that its citizens and policymakers need to invest in preventing flood damage.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.2
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• pp.67-76
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• 2012

In this study, we established objective appraisal standard by applying newly made appraisal standard to those areas equipped with the protection system targeted to the Mobility handicapped announced in this edition (issue 5, volume 9(Oct., 2010)) beyond simple evaluation related to protector satisfaction. Additionally, we achieved efficient budget execution by conducting the preliminary estimation assessment regarding those areas on which recognition devices should be newly deployed. Through the assessment of the system coordination, the maximum safety distance is proved to be 72.2m. On the basis of this result, we applied dangerous grade to the deployment of recognition devices considering both psychological and accidental risk. With this, we proposed valuation basis to enable us to do future business. Based on this assessment standard, the degree of risk is proved to decrease by 35.2% compared to before conducting the demonstration project in terms of evaluation of comprehensive risk regarding intended areas. Additionally, we confirmed the fact that the degree of risk can decrease by 33.1% totally after having recognition devices built according to the deployment standard within budget. Furthermore, comprehensive risk can decrease up to 94% compared to the level of the demonstration project even though we spend 21.9% less of the existing budget. Hence, we can say that the deployment method of recognition devices related to the degree of risk is applied efficiently in the near future in terms of controlling comprehensive risk and cutting down budget through this study.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.30 no.4
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• pp.719-734
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• 2020

This paper proposes a new measurement scheme for estimating the processing level according to risk when performing de-identification in the use of personal information by practitioners in the organization in line with the recently revised Data 3 Act. Our proposed methods considered the surrounding circumstances surrounding the data, not just the data, for risk measurement, and divided the data situation into three categories more systematically so that it can be applied in all areas in a general-purpose environment, the data utilization environment, and the data (self) so that it can be calculated quantitatively based on each context risk according to the presented classification. The proposed method is designed to calculate the risk of existing de-identifiable information in a quantitative manner so that personal information controller in general organizations can use it in practice, not just in the qualitative judgment of experts.

• Journal of the Society of Naval Architects of Korea
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• v.49 no.6
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• pp.447-460
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• 2012

In this study, the shutdown system of the fuel gas supply system is designed based on the Safety Integrity Level of IEC 61508 and IEC 61511. First of all, the individual risk($10^{-4}$/year) and the risk matrix which are the risk acceptance criteria are set up for the qualitative risk assessment such as the HAZOP study. The natural gas leakage at the gas supply pipe is identified as the highest risk among the hazards identified through the HAZOP study and as a safety instrumented function the shutdown function for leakage was defined. SIL 2 and PFD($2.5{\cdot}10^{-3}$) for the shutdown function are determined by the layer of protection analysis(LOPA). The shutdown system(SIS) carrying out the shutdown function(SIF) is verified and designed according to qualitative and quantitative requirements of IEC 61508 and IEC 61511. As a result of SIL verification and SIS conceptual design, the shutdown system is composed of two gas detectors voted 1oo2, one programmable logic solver, and two shutdown valve voted 1oo2.