• Title/Summary/Keyword: Risk value

Search Result 2,503, Processing Time 0.035 seconds

Optimal Target Low-density Lipoprotein Level for Reducing the Risk of Atherosclerotic Cardiovascular Diseases: A Systematic Review and Meta-analysis

  • Min-Gyo Jang;Yeung-Eun Son;Hye Duck Choi;Junwoo Kim;Tae-Eun Kim;Kwang-Hee Shin
    • Korean Journal of Clinical Pharmacy
    • /
    • v.33 no.4
    • /
    • pp.270-277
    • /
    • 2023
  • Background: As per guidelines for treating dyslipidemia, the recommended low-density lipoprotein cholesterol (LDL-C) level in extremely high-risk patients, including those with coronary artery diseases is <55 mg/dL. Although this recommendation has been adopted in the guidelines for dyslipidemia in various countries, there is limited evidence of its efficacy in reducing cardiovascular diseases (CVDs), especially among East Asian patients. This study aimed to investigate whether an LDL-C value below 55 mg/dL is associated with decreased risk of CVDs. Methods: Seven clinical trials including 50,970 patients that compared intensive lipid-lowering therapy with less therapy or placebo in patients who had >6 months of follow-up, those with a sample size of ≥150 were selected as the final literature for analysis. Risk ratios (RR) using random effects were represented with 95% confidence intervals (CI) for the reliability of the results. Results: An LDL-C level of <55 mg/dL was related to significantly reduced events of major CVDs (RR: 0.88; 95% CI: 0.80-0.98) and myocardial infarction (RR: 0.81; 95% CI: 0.73-0.90) and a reduced risk of ischemic stroke (RR 0.79; 95% CI 0.69-0.89, mean follow-up=2 years). However, an LDL-C level below 55 mg/dL did not reduce the incidence of CVD in intensive therapy in East Asian patients. Conclusions: A goal LDL-C value below 55 mg/dL was identified to be related to a decreased risk of developing CVD. However, the relation to LDL-C below 55 mg/dL with a decreased risk of CVD was not observed in East Asian patients.

Measurement and Analysis of Risk Voltages in a Grounding System (접지계에서 위험전압의 측정과 분석)

  • Jin, Chang-Hwan;Park, Dae-Won;Seo, Jae-Seok;Kil, Gyung-Suk;Gil, Hyeong-Jun
    • Proceedings of the KSR Conference
    • /
    • 2011.10a
    • /
    • pp.3099-3103
    • /
    • 2011
  • In measurement of risk voltages; the step and touch voltage, the distance between the current electrode and the ground electrode recedes up to several hundred meters as the scale of grounding system increases. This paper dealt with the measurement method of risk voltage in a restricted space. The risk voltage was analyzed depending on the distance and the direction of the current electrode from the ground electrode in a $10[m]{\times}10[m]$ mesh grounding system. The average value of risk voltages measured at a point 20 [m] away from the current electrode was deviated below 5 [%] from that measured at 100 [m] point. Consequently, the evaluation of risk voltage of a large-scale grounding system buried in a spatially restricted place is available if the current electrode is installed in symmetry to the ground electrode.

  • PDF

Technology Innovation Activity and Default Risk of Firms : Focusing on a Mediation Effect of Profitability (기술혁신활동이 부도위험에 미치는 영향 : 수익성 매개효과를 중심으로)

  • Kim, Jinsu;Lee, HyunChul
    • Knowledge Management Research
    • /
    • v.11 no.1
    • /
    • pp.19-35
    • /
    • 2010
  • This study explores the effects of technology innovation activity on a profitability and the default risk of firms. Sample for this study consists of manufacturing firms listed on the Korea Stock Exchange from 1st January 2000 to 31st December 2007. We use of R&D ratio as a proxy of technology innovation activity. The default probability proxied for the default risk of firms is measured by the Merton's (1974) model where accounts for a market value of firms and a volatility of it. This study provides evidence that technology innovation activity has a positive effect on a profitability, but a negative effect on the default risk of firms. Our study also finds the significant mediation effect of profitability that the enhancement in profitability resulting from technology innovation activity lowers the default risk of firms.

  • PDF

A Study on Risk Response against Ship Fire using Robot

  • Park, Dea-Woo;Park, Young-Suk;Nam, Jae-Min
    • Journal of information and communication convergence engineering
    • /
    • v.9 no.2
    • /
    • pp.230-234
    • /
    • 2011
  • It is endeavoring for sea safety and fire[1] at sea prevention solidifying control of standard technology and safety supervision aspect in IMO[2] but sea accident and ship fire are happening continuously. Because using Robot in artistic talent of ship in this treatise, studied that correspond to Risk and manage. Attach fire perception sensor for Robot's Risk confrontation, and because using infrared rays sensor, TOUCH SWITCH, sound perception sensor, gas perception sensor, light perception sensor that is threaded in Robot and is achieved, controlled Robot, and establish Low-High value the speed of sound output use and DC MOTOR and COM SEN of when indicate Risk confrontation to Robot and establish Robot's Risk confrontation administration action.

Development of Risk-Based Inspection(RBI) Technology for LNG Plant Based on API RP581 Code (API RP 581 Code를 기반으로한 LNG 플랜트의 Risk-Based Inspection(RBI) 기술 개발)

  • Choi, Song-Chun;Choi, Jae-Boong;Hawang, In-Ju
    • Corrosion Science and Technology
    • /
    • v.11 no.5
    • /
    • pp.179-183
    • /
    • 2012
  • As one of promising solutions to overcome high oil price and energy crisis, the construction market of high value-added LNG plants is spotlighted world widely. The purpose of this study is to introduce LNG-RBI system to develop risk assessment technology with RAM(Reliability, Availability, Maintainability) modules against overseas monopolization. After analyzing relevant specific features and their technical levels, risk assessment program, non-destructive reliability evaluation strategy and safety criteria unification class are derived as core technologies. These IT-based convergence technologies can be used for enhancement of LNG plant efficiency, in which the modular parts are related to a system with artificial optimized algorithms as well as diverse databases of facility inspection and diagnosis fields.

Trend Analysis for Risk Management of Construction Project using P.M.I. Techniques (P.M.I. 기법을 이용한 국내 건설업체 리스크관리 실태 분석)

  • 정병화;정영식
    • Journal of the Korean Society of Safety
    • /
    • v.16 no.4
    • /
    • pp.115-122
    • /
    • 2001
  • Recently construction enterprises involves more occurred with increase of size and complxity of construction works. Risk management is one of the key project management process. Numerous tools are available to support the various phases of the risk management process. We present the results of a study designed to identify the tools that are most widely used and those that are associated with successful project management in general, and in effective project risk management in particular. The study is based on a questionnaire administered to a sample of project managers from construction enterprises. The response data was analyzed in order to find which tools are mon likely to be used in the those organizations that report better project management performance and in those that value the contribution of risk management processes.

  • PDF

Analysis of Farm Management Stabilization Effects Using Weather Derivatives for Apple Farmers in Kyeongpuk District (날씨파생상품을 이용한 경북지역 사과농가 경영안정 효과 분석)

  • Yun, Sung-Wuk;Choi, Jang-Hoon;Chung, Won-Ho
    • Korean Journal of Organic Agriculture
    • /
    • v.28 no.4
    • /
    • pp.459-475
    • /
    • 2020
  • This study analyzes weather derivatives as an alternative risk management tool to stabilize farm revenue to complement the existing crop insurance program which suffers from asymmetric information problems such as adverse selection, moral hazard, and verifiability. We estimated apple yield functions to observe the relationship between yields and weather indices such as temperature and precipitation. Based on the estimated yield functions we designed weather futures and options products underlying temperature and precipitation, and calculated the prices of futures and options by two different approaches, historical distribution and Monte Carlo simulation. We found that weather futures and options stabilize farm revenue based on the estimated four risk indicators: Coefficient of Variation, Value at Risk, Certainty Equivalence, and Risk Premium. As a result, weather derivatives could be considered as a potential farm risk management tool through studying more in legal and institutional strategies and developing various derivatives products.

A descriptive spatial analysis of bovine tuberculosis disease risk in 2015 in Gangwon-do, Republic of Korea

  • Kim, Eu-Tteum;Pak, Son-Il
    • Journal of Preventive Veterinary Medicine
    • /
    • v.41 no.2
    • /
    • pp.79-83
    • /
    • 2017
  • In this study, we used a choropleth map to explore the spatial variation of the risk of cattle herds being bovine tuberculosis (BTB) positive in Gangwon-do in 2015. The map shows that the risk of being BTB-positive was lower in provinces located in the middle of Gangwon-do (Wonju, Youngwol, Peongchang, and Kangneung) than in other provinces. In addition, one province located in the north (Goseong) had a low risk of BTB. The estimate for the intercept of the spatial lag model was 0.66, and the spatial autocorrelation coefficient (lambda) was 0.20 (Table 1). The Moran's I was 0.33 with p-value of 0.02. In 2015, provinces located in the North West (Hwacheon) and East (Donghae) of Gangwon-do had a higher BTB risk. We identified some specific provinces at low BTB-positive risk, information that may prove useful for control of BTB in the study area.

RISK FRAMEWORK FOR NEXT GENERATION NUCLEAR POWER PLANT CONSTRUCTION

  • John Walewski ;Stuart Anderson;Jaeheum Yeon;Amy Kim
    • International conference on construction engineering and project management
    • /
    • 2013.01a
    • /
    • pp.451-458
    • /
    • 2013
  • This research documents the initial findings and recommendations for developing a risk management tool to assess and quantify the risks associated with the construction of the next generation of nuclear power plants. The proposed tool builds upon the Construction Industry Institute's International Project Risk Assessment (IPRA) Best Practice. This paper provides an overview of the investigation to assess the unique risk elements pertaining to nuclear power plant construction and documents the preliminary findings from historical project performance data to better understand the function and use of the IPRA's Relative Impact value.

  • PDF

Driving Safety Analysis for vehicles Against High Wind on the Bridges Using Extreme Value Statistics (극치통계분석을 이용한 교량상판 풍하중에 대한 차량주행 안전도 평가)

  • Chung, Jee-Seung
    • Journal of the Korean Society of Safety
    • /
    • v.25 no.3
    • /
    • pp.112-117
    • /
    • 2010
  • This study presents a methodology to evaluate the driving safety of vehicles against localized high wind on the roads over the valleys or along the coasts. Risk level for vehicle accident is derived from the side slip caused by cross wind, and then safety criteria based on reliability for driving stability are defined. The level of safety is classified according to probability of exceeding against wind speed using the concept of extreme value statistics. To attain the safety level of vehicle on bridges, numerical simulations using Computational Fluid Dynamics(CFD) are performed. Based on this result, risk reduction and quality improvement is expected through analysis for each alternative in bridges design, construction and operation & maintenance stage with proposed process