• 한국환경농학회지
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• 제42권3호
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• pp.193-202
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• 2023

Residue monitoring of propiconazole (PCZ) in cabbage, shallot, and spinach was conducted under multi-trial greenhouse conditions. This study aimed to understand the fate of the applied fungicide in these vegetables. Furthermore, the associated health risk of PCZ in leafy vegetables was assessed through dietary risk assessment. Commercially available PCZ (22% suspension concentrate) was administered thrice according to the OECD fungicide application interval guideline. The plant samples were extracted using a slightly modified QuEChERS technique and analyzed using gas chromatography-tandem mass spectrometry. The average PCZ recovery was between 84.5% and 117.6%, with a <5% coefficient of variance. The dissipation of PCZ residue in cabbage, shallot, and spinach after 14 days was 96%, 90%, and 99%, respectively, with half-lives of <5 days. Meanwhile, dietary risk assessments of PCZ residues in the studied vegetables using the risk quotient (RQ) were significant < 100 (RQ < 100). Thus, the population groups considered in this study were not at substantial risk from consuming leafy vegetables sprayed with PCZ following critical, good agricultural practices.

• Fisheries and Aquatic Sciences
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• 제27권2호
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• pp.66-75
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• 2024

Heavy metals are naturally found in the ecosystem, and their presence in the freshwater river is increasing through anthropogenic activities which pose a threat to living beings. In this study, heavy metal concentrations (Zn, Mn, Cu, Cd, Cu, Cr, Pb, and Ni) in different organs (muscle, skin, and gill) of fish from the Padma River were evaluated to quantify, and compare the contamination levels and related human health risks. The results revealed that the heavy metal concentrations in the water, surface sediments, and fish taken from the Padma River were far below the WHO/USEPA's permitted limits. The estimated daily intake (EDI) value in muscle was less than the tolerable daily intake (TDI). The target hazard quotient (THQ) and hazard indexes (HI) were less than 1, showing that consumers face no non-carcinogenic risk (CR). CR values of Cu, Cd, Cr, Pb, and Ni ranged from 4.00 × 10^-8 to 6.35 × 10^-6, less than 10^-4, and total carcinogenic risk (CRt) values ranged from 9.85 × 10^-6 to 1.10 × 10^-5, indicating some pose a CR from consumption of those fish from the Padma River. To establish a more accurate risk assessment, numerous exposure routes, including inhalation and cutaneous exposure, should be explored.

• 한국토양비료학회지
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• 제49권5호
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• pp.584-588
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• 2016

The current study was carried out to investigate total and inorganic arsenic (As) concentrations in 112 rice samples (husked rice and polished rice) grown around the abandoned mining areas and to estimate the potential health risk through dietary intake of rice in Korea. Mean concentrations of total As in husked rice and polished rice were 0.23 and $0.13mg\;kg^{-1}$, respectively. Also, average inorganic As concentrations in husked rice and polished rice were 0.09 and $0.05mg\;kg^{-1}$, respectively. These levels are lower than the standard guideline value ($0.2mg\;kg^{-1}$) for inorganic As in polished rice recommended by Korea Ministry of Food and Drug Safety and Codex. For health risk assessment, the average values of cancer risk probability was $5.7{\times}10^{-5}$ which was less than the acceptable cancer risk of $10^{-6}{\sim}10^{-4}$ for regulatory purpose. Also, hazard quotient values were lower than 1.0. Therefore, these results demonstrated that human exposure to inorganic As through dietary intake of rice collected from abandoned mining areas might not cause adverse health effects.

• 한국환경보건학회:학술대회논문집
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• 한국환경보건학회 2004년도 International Conference Global Environmental Problems and their Health Consequences
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• pp.173-177
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• 2004

The acute toxicities of two major anti-pathogenic veterinary medicines, i.e., ciprofloxacin and enrofloxacin, and six benzimidazole anthelmintics, i.e., albendazole, thiabendazole, flubendazole, febantel, fenbendazole, and oxfendazole, were evaluated with a marine bacterium, Vibrio fischeri, and invertebrate Daphnia magna. These veterinary medical products have been widely used for farm animals, but their impact on aquatic fauna has seldom been investigated. In general, daphnids responded as much as 3 orders of magnitude more sensitively to the tested pharmaceuticals than the microbes. For Daphnia, the most toxic product among the tested anthelmintics was fenbendazole, followed by flubendazole > albendazole ${\approx}$ febantel > thiabendazole > oxfendazole. Daphnids' EC50 values obtained from 48 to 96 hrs of fenbendazole exposure ranged from 2.7 to 6.3 ug/L. The mixture toxicity of the test pharmaceuticals was generally additive in nature and was well predicted by a concentration addition model. Using the predicted no effect concentrations (PNECs) of the benzimidazole derivatives estimated from this study, and predicted environmental concentrations (PECs) of these pharmaceuticals, the risk quotients of each anthelmintics were calculated. Most of the test anthelmintic compounds resulted in risk quotients greater than 1. Especially, risk quotient for fenbendazole was 2,791, which strongly indicates this compound might cause severe ecological consequences, should no future action be taken. This study is the first report on the aquatic toxicities and potential ecological risk of major anthelmintic and antimicrobial veterinary products in Korea. The result of this study provides information necessary for conducting more detailed ecological risk assessment of pharmaceutical products in ambient water and guiding proper management decision.

• 대한환경공학회지
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• 제38권7호
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• pp.371-376
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• 2016

본 연구에서는 에폭시 수지 갱생 옥내급수관 수돗물에 대해 비스페놀-A 실태조사를 실시하였고, 비스페놀-A가 수돗물 음용에 있어 인체에 미치는 영향을 파악하기 위해 위해성 평가를 실시하였다. 원수 중 비스페놀-A는 50~118 ng/L로 채취된 모든 시료에서 정량한계 10 ng/L 이상으로 검출되었다. 이것은 주변지역의 하수 방류수나 지천에 의한 비스페놀-A 유입에 의한 것으로 판단된다. 정수에서의 비스페놀-A는 불검출되었으며, 고도정수처리 공정에서 모두 제거된 것으로 추정되었다. 응집-침전과정과 오존 및 염소에 의해 산화되어 제거되거나 다른 산화 부산물질로 변화한 것으로 판단된다. 옥내급수관 수돗물의 경우, 에폭시 갱생공사를 실시하지 않은 수돗물 모두에서 비스페놀-A는 검출되지 않았다. 그러나 에폭시 갱생공사를 실시한 옥내급수관 수돗물에서 비스페놀-A가 불검출에서 최대 521 ng/L로 범위로 검출되었으며, 채취된 시료의 68%가 정량한계 이상으로 검출되었다. 검출된 비스페놀-A의 최대값(521 ng/L)에 대한 위해도 지수 산정 결과, 위해도 지수(HQ)는 약 0.004로 수돗물 섭취에 의한 위해판단 기준값 0.1 이하로 나타나 음용에 안전한 것을 확인하였다.

• 대한환경공학회지
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• 제29권2호
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• pp.163-168
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• 2007

국내 5개 폐광산 지역의 갱내수 및 배출수에 대해 화학적 분석 및 생물학적인 독성 평가를 통한 생태 위해성 평가를 실시하였다. 본 연구에서 선정한 9가지 중금속의 화학적 분석 결과, 거의 모든 지점에서 높은 중금속 농도가 검출되었으며, 특히 송천, 낙동, 덕음 지역에서는 상대적으로 비소가 높게 검출되었고, 낙동 지역은 하류까지 전체적으로 각 항목의 중금속이 높은 농도로 존재하였다. 통합 방류수 독성 평가(WET)에 기초해 Vibrio fisheri, Selenastrum capricornutum, Daphnia magna를 이용한 생물학적 독성 평가 결과, 모든 지점에서 높은 독성이 나타났다. 유출수가 처음 흐르는 갱구에서 가장 높은 독성이 나타났으며, S. capricornutum에 대한 독성이 모든 지점에 걸쳐 $1.3\sim32.0$ TU 사이의 독성이 나타나 독성 민감도가 가장 높은 것으로 나타났다. 각각의 독성 평가 종에 따른 독성 미감도 차이는 폐광사의 위해성을 평가함에 있어 두 종 이상의 평가 종이 사용되어야 함을 의미한다. HQ(Hazard Quotient) 개념을 적용한 생태 위해성 평가 결과, 폐광산에서 분석된 대부분의 중금속에 대해 HQ 값이 1보다 훨씬 크게 나타났으므로, 폐광산의 중금속에 대한 영향은 심각한 정도의 위해도를 가지고 있다고 판단된다. 한편, 생물학적 독성은 유하 거리의 증가에 따라 감소하는 것으로 나타났다. 따라서, 폐광산의 복원이나 생태 위해성 평가 시 지점별로 희석률뿐 아니라 DOM, 경도 등 환경인자들이 고려되어야 할 것으로 판단된다.

• 대한영양사협회학술지
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• 제27권4호
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• pp.248-262
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• 2021

This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia risk factors. We developed the program including nutrition, exercise, cognitive training, vascular disease prevention, and motivation. One- hundred and fifty-three participants aged 60~79 years with at least 1 dementia risk factor were randomly assigned in a 1:1:1 ratio to the facility-based intervention (FMI), home-based intervention (HMI), and the control group. The nutrition education program consisted of 10 classes over 24 weeks: the FMI received 7 group sessions and three 1:1 sessions, the HMI received 4 group sessions and three 1:1 sessions with 3 homework sessions. The Nutrition Quotient for Elderly (NQ-E) and the Mini Nutritional Assessment (MNA) were used to evaluate nutritional status. The Repeatable Battery for the Assessment Neuropsychological Status (RBANS), Korean Mini-Mental State Examination (K-MMSE), and the Cognitive Complaint Interview (CCI) were used to evaluate cognitive functions. A total of 136 people completed the program with an 11.1% dropout rate. The NQ-E (P=0.009) and RBANS (P=0.001) scores significantly increased in the FMI (N=45) and HMI (N=49) groups compared to the control group (N=42) after the study. The changes in the score of MNA and CCI did not differ significantly between groups. In conclusion, the nutritional intervention which focused on the MIND diet as a part of a multi-domain intervention program had a positive effect on the improvement of healthy eating habits and cognitive function scores in the high-risk dementia group.

• Journal of Nutrition and Health
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• 제52권6호
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• pp.604-617
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• 2019

본 연구는 유아의 영양상태에 미치는 행동적 요인을 확인하기 위하여, 어린이 식행동 검사 (DBT)와 어린이영양지수 (NQ)를 활용하여 경산시 소재 어린이집과 유치원에 다니는 만 2~6세 유아의 부모 1,103명을 대상으로 식행동과 식품섭취상태를 평가하였다. 아이의 식행동을 접근회피성, 감각예민성, 과활동성 그리고 불규칙성의 4가지로 분류하고, 식행동 유형별 위험군을 분류하였다. 4가지 식행동 유형별 위험군 어린이들의 식습관과 영양섭취 수준을 파악하고자 양호군과 비교분석하여 유아의 영양상태에 영향을 미치는 식행동 요인을 규명하였다. 본 연구의 결과를 요약하면, 첫째, 조사대상자의 NQ점수는 절제요인 (80.5점), 규칙요인 (63.9점), 실천요인 (63.2점), 균형요인 (56.2점), 다양요인 (45.5점) 순으로 나타나 절제요인을 제외한 모든 요인에서 영양불량으로 판정되었으며, 5개 등급을 구분한 결과 하위등급 (22.2%)과 최하위등급 (12.6%)이 전체 조사대상자의 1/3에 달하였다. 둘째, 4가지 식행동 유형별 위험군을 판정한 결과, 감각예민성은 28.7%, 접근회피성은 26.4%, 불규칙성은 25.7%, 과활동성은 22.2%으로 나타났다. 셋째, 4가지 식행동 유형별 위험군 어린이들의 식습관과 영양섭취수준을 파악하고자 양호군 어린이들의 어린이 영양지수 (NQ)와 비교분석 한 결과, 각 식행동 유형별 뚜렷한 차이를 보였다. 접근회피성과 감각예민성 유형에서는 양호군에 비해 위험군이 균형과 다양요인 점수가 유의하게 낮았다. 균형요인의 세부항목 중 잡곡밥, 과일, 콩 또는 콩제품, 달걀 섭취와 다양요인의 세부항목 중 반찬을 골고루 섭취하는지, 채소반찬의 섭취 가짓수, 김치섭취에서 유의하게 낮은 섭취빈도를 나타냈다. 과활동성 유형에서는 양호군에 비해 위험군이 절제요인 점수가 유의하게 낮았다. 세부항목 중 단 음식 섭취에서 유의하게 높은 섭취 빈도를 보였다. 불규칙성 유형에서는 양호군에 비해 위험군이 다양과 규칙 및 실천요인에서 유의하게 낮은 점수를 나타냈다. 다양요인의 세부항목 중 반찬을 골고루 섭취하는지, 채소반찬의 섭취 가짓수, 김치섭취에서, 규칙요인 중 아침식사와 규칙적인 식사 빈도에서, 실천요인 중 음식 꼭꼭 씹어먹기와 식사 전 손씻기 빈도에서 유의하게 낮은 빈도를 나타냈다. 본 연구결과를 토대로 하여 기존의 획일적인 영양교육프로그램이 아닌 각 아이의 기질을 바탕으로 한 맞춤형 영양교육프로그램이 개발되는데 기초자료로 활용할 수 있기를 기대한다.

• 한국환경보건학회지
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• 제32권5호
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• pp.398-403
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• 2006

Indoor air quality can be affected by indoor sources, ventilation, decay and outdoor levels. Understanding the effectiveness of indoor air quality control depends on knowledge of the characteristics of air pollutants in indoor air, especially their quantities and persistence, and the relevance of indoor sources to these factors. Toluene within new and established houses has been determined and factors significant to its presence have been identified. A total of 30 selected houses in Seoul, Asan and Daegu areas that were constructed within 4 years and over 4 years of construction were measured the concentration of toluene from July to September in 2004. Toluene emission decay of double-exponential model exhibited good fit of $Y=276.37e^{-1.21x}(R^{2}=0.34,\;P=0.06)$ for 2 years and then $Y=51.54e^{-0.11x}(R^{2}=0.40,\;P=0.0)$ from 23 years in new houses. In case of living in new houses, noncarcinogenic health effects of exposure to toluene was 1.38 of hazard quotient (HQ) comparing to toluene reference dose of 0.13 mg/kg-day.

• 한국지하수토양환경학회지:지하수토양환경
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• 제26권3호
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• pp.37-49
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• 2021

There is domestic Soil Contamination Warning Standard (SCWS) as remediation standard concentration of contaminated soils. No risk should be observed at soil concentration less than SCWS. Therefore, SCWS was evaluated to confirm the risk assessment. Background Concentration of Soil (BGC) and target remediation concentration were also assessed. The results show that Excess Cancer Risk (ECR) of SCWS was the highest in the groundwater intake pathway (Adult: 6.27E-04, Child: 2.81E-04). Total Cancer Risk (TCR) was 7.76E-04 and 4.30E-04 for adult and child, exceeding reference value (10^-6). Hazard Quotient (Non-Carcinogenic Risk, HQ) was the highest in the indoor air inhalation pathway (Adult: 3.64E+03, Child: 8.74E+02). Hazard Index (Total Non-Carcinogenic Risk, HI) exceeded reference value 1. ECR of the BGC was the highest in the groundwater intake pathway (Adult: 1.71E-04, Child: 7.67E-05). TCR was 2.12E-04 for adults and 1.17E-04 for children, exceeding the reference value (10^-6). HQ was the highest in groundwater intake pathway (Adult: 4.10E-01, Child: 1.84E-01). HI was lower than reference value 1 (Adult: 4.78E-01, Child: 2.50E-01). The heavy metal affecting ECR was Arsenic (As). The remediation-concentration of As was 7.14 mg/kg which is higher than BGC (6.83 mg/kg). TCR of As should be less than reference value (10^-6), but it was higher for all of SCWS, BGC and target remediation concentration. Therefore, it is suggested that risk assessment factors should be re-evaluated to fit domestic environmental settings and SCWS should be induced to satisfy the risk assessment.