• Title/Summary/Keyword: Risk evaluation

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Effectiveness of Two-dose Varicella Vaccination: Bayesian Network Meta-analysis

  • Kwan Hong;Young June Choe;Young Hwa Lee;Yoonsun Yoon;Yun-Kyung Kim
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.55-63
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    • 2024
  • Purpose: A 2-dose varicella vaccination strategy has been introduced in many countries worldwide, aiming to increase vaccine effectiveness (VE) against varicella infection. In this network meta-analysis, we aimed to provide a comprehensive evaluation and an overall estimated effect of varicella vaccination strategies, via a Bayesian model. Methods: For each eligible study, we collected trial characteristics, such as: 1-dose vs. 2-dose, demographic characteristics, and outcomes of interest. For studies involving different doses, we aggregated the data for the same number of doses delivered into one arm. The preventive effect of 1-dose vs. 2-dose of varicella vaccine were evaluated in terms of the odds ratio (OR) and corresponding equal-tailed 95% confidence interval (95% CI). Results: A total of 903 studies were retrieved during our literature search, and 25 interventional or observational studies were selected for the Bayesian network meta-analysis. A total of 49,265 observed individuals were included in this network meta-analysis. Compared to the 0-dose control group, the OR of all varicella infections were 0.087 (95% CI, 0.046-0.164) and 0.310 (95% CI, 0.198-0.484) for 2-doses and one-dose, respectively, which corresponded to VE of 69.0% (95% CI, 51.6-81.2) and VE of 91.3% (95% CI, 83.6-95.4) for 1- and 2-doses, respectively. Conclusions: A 2-dose vaccine strategy was able to significantly reduce varicella burden. The effectiveness of 2-dose vaccination on reducing the risk of infection was demonstrated by sound statistical evidence, which highlights the public health need for a 2-dose vaccine recommendation.

Analysis of Autonomous Vehicles Risk Cases for Developing Level 4+ Autonomous Driving Test Scenarios: Focusing on Perceptual Blind (Lv 4+ 자율주행 테스트 시나리오 개발을 위한 자율주행차량 위험 사례 분석: 인지 음영을 중심으로)

  • Seung min Oh;Jae hee Choi;Ki tae Jang;Jin won Yoon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.23 no.2
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    • pp.173-188
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    • 2024
  • With the advancement of autonomous vehicle (AV) technology, autonomous driving on real roads has become feasible. However, there are challenges in achieving complete autonomy due to perceptual blind areas, which occur when the AV's sensory range or capabilities are limited or impaired by surrounding objects or environmental factors. This study aims to analyze AV accident patterns and safety issues of perceptual blind area that may occur in urban areas, with the goal of developing test scenarios for Level 4+ autonomous driving. It utilized AV accident data from the California Department of Motor Vehicles (DMV) to compare accident patterns and characteristics between AVs and conventional vehicles based on activation status of autonomous mode. It also categorized AV disengagement data to identify types and real-world cases of disengagements caused by perceptual blind areas. The analysis revealed that AVs exhibit different accident types due to their safe driving maneuvers, and three types of perceptual blind area scenarios were identified. The findings of this study serve as crucial foundational data for developing Level 4+ autonomous driving test scenarios, enabling the design of efficient strategies to mitigate perceptual blind areas in various scenarios. This, in turn, is expected to contribute to the effective evaluation and enhancement of AV driving safety on real roads.

Effect of Acupotomy Treatment for Lateral Epicondylitis: A Systematic Review and Meta-Analysis (외측상과염의 도침 치료에 대한 체계적 문헌고찰 및 메타분석)

  • Jong Chan Choi;Min Jun Ji;Kyung Jun Ser;Do Young Kwon;Jae Eun Yang;Ji Hyang Gu;Eun Jung Lee;Min Seok Oh
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.2
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    • pp.101-134
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    • 2024
  • Objectives The purpose of this study is to observe the effectiveness of acupotomy treatment for lateral epicondylitis by comparing it with various control groups. Methods We searched 11 domestic and international databases for systematic reviews and meta-analysis. The subjects were studies published from January 1, 2017 to September 1, 2023, and only randomised controlled trials were included. Results 208 studies were searched, of which 21 studies were finally selected. Among the studies published after 2017, the largest number of studies was published in 2019. The average number of participants per study was 72.28±20.26 and the average age was in the 40s. The most frequent intervention in the study was acupotomy alone, and the treatment most often mentioned as a control group was local nerve block. The most used evaluation tool is efficiency. Acupotomy+manipulation had statistically better effect than that of local nerve block in terms of pain (standard mean difference -1.87, 95% confidence interval, -2.18 to -1.57, p<0.00001) and elbow joint function (standard mean difference 2.25, 95% confidence interval, 1.65 to 2.86, p<0.00001). Conclusions As a result of the meta-analysis, the effect of acupotomy added manual therapy treatment was statistically significant compared to the local nerve block frequently used for lateral epicondylitis. Based on these results, it appears that more research on combination treatments other than acupotomy treatment will be needed. Also, it appears that more large-scale randomized controlled studies that strictly adhere to the standards for reporting interventions in controlled trials of acupuncture, risk of bias 2 criteria will be needed.

An Experimental Study on the Estimation Method of Overtopping Discharge at the Rubble Mound Breakwater Using Wave-Overtopping Height (월파고를 이용한 사석경사제의 월파량 산정방법에 관한 실험적 연구)

  • Dong-Hoon Yoo;Young-Chan Lee;Do-Sam Kim;Kwang-Ho Lee
    • Journal of Navigation and Port Research
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    • v.48 no.3
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    • pp.192-199
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    • 2024
  • Wave overtopping is a significant natural hazard that occurs in coastal areas, primarily driven by high waves, particularly those generated during typhoons, which can cause coastal flooding. The development of residential and commercial areas along the coast, driven by increasing social and economic demands, has led to a concentration of people and assets in these vulnerable areas. This, coupled with long-term sea level rise and an increase in typhoon frequency, has heightened the risk of coastal hazards. Traditionally, the evaluation of wave overtopping volumes has relied on directly measuring the collected volume of water that exceeds the crest height of structures through hydraulic model experiments. These experiments are averaged over a specific measurement period. However, in this study, we propose a new method for estimating individual wave overtopping volumes. We utilize the temporal variation of wave overtopping heights to develop an observation system that can quantitatively assess wave overtopping volumes in actual coastal areas. To test our method, we conducted hydraulic model experiments on rubble mound breakwaters, which are commonly installed along the Korean coast. We introduce wave overtopping discharge coefficients, assuming that the inundation velocity from the structure's crest is the long-wave velocity. We then predict overtopping volumes based on wave overtopping heights and compare and review the results with experimental data. The findings of our study confirm the feasibility of estimating wave overtopping volumes by applying the overtopping discharge coefficients derived in this study to wave overtopping heights.

The Value of Adding Ductography to Ultrasonography for the Evaluation of Pathologic Nipple Discharge in Women with Negative Mammography

  • Younjung Choi;Sun Mi Kim;Mijung Jang;Bo La Yun;Eunyoung Kang;Eun-Kyu Kim;So Yeon Park;Bohyoung Kim;Nariya Cho;Woo Kyung Moon
    • Korean Journal of Radiology
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    • v.23 no.9
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    • pp.866-877
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    • 2022
  • Objective: The optimal imaging approach for evaluating pathological nipple discharge remains unclear. We investigated the value of adding ductography to ultrasound (US) for evaluating pathologic nipple discharge in patients with negative mammography findings. Materials and Methods: From July 2003 to December 2018, 101 women (mean age, 46.3 ± 12.2 years; range, 23-75 years) with pathologic nipple discharge were evaluated using pre-ductography (initial) US, ductography, and post-ductography US. The imaging findings were reviewed retrospectively. The standard reference was surgery (70 patients) or > 2 years of follow-up with US (31 patients). The diagnostic performances of initial US, ductography, and post-ductography US for detecting malignancy were compared using the McNemar's test or a generalized estimating equation. Results: In total, 47 papillomas, 30 other benign lesions, seven high-risk lesions, and 17 malignant lesions were identified as underlying causes of pathologic nipple discharge. Only eight of the 17 malignancies were detected on the initial US, while the remaining nine malignancies were detected by ductography. Among the nine malignancies detected by ductography, eight were detected on post-ductography US and could be localized for US-guided intervention. The sensitivities of ductography (94.1% [16/17]) and post-ductography US (94.1% [16/17]) were significantly higher than those of initial US (47.1% [8/17]; p = 0.027 and 0.013, respectively). The negative predictive value of post-ductography US (96.9% [31/32]) was significantly higher than that of the initial US (83.3% [45/54]; p = 0.006). Specificity was significantly higher for initial US than for ductography and post-ductography US (p = 0.001 for all). Conclusion: The combined use of ductography and US has a high sensitivity for detecting malignancy in patients with pathologic nipple discharge and negative mammography. Ductography findings enable lesion localization on second-look post-ductography US, thus facilitating the selection of optimal treatment plans.

Governance research for Artificial intelligence service (인공지능 서비스 거버넌스 연구)

  • Soonduck Yoo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.24 no.2
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    • pp.15-21
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    • 2024
  • The purpose of this study is to propose a framework for the introduction and evaluation of artificial intelligence (AI) services not only in general applications but also in public policies. To achieve this, the study explores AI service management and governance toolkits, providing insights into how to introduce AI services in public policies. Firstly, it offers guidelines on the direction of AI service development and what aspects to avoid. Secondly, in the development phase, it recommends using the AI governance toolkit to review content through checklists at each stage of design, development, and deployment. Thirdly, when operating AI services, it emphasizes the importance of adhering to principles related to 1) planning and design, 2) the lifecycle, 3) model construction and validation, 4) deployment and monitoring, and 5) accountability. The governance perspective of AI services is crucial for mitigating risks associated with service provision, and research in risk management aspects should be conducted. While embracing the advantages of AI, proactive measures should be taken to address limitations and risks. Efforts should be made to efficiently formulate policies using AI technology to create high value and provide meaningful societal impacts.

Endovascular Treatment of Incidentally Found Multiple Aneurysms Originating from a Bronchial Artery: A Case Report (우연히 발견된 하나의 기관지 동맥에서 발생한 다발성 동맥류에 대한 혈관내 치료: 증례 보고)

  • Minhyeok Yoon;Jung Guen Cha;Jongmin Park;Sang Yub Lee;See Hyung Kim;Jihoon Hong;Byunggeon Park
    • Journal of the Korean Society of Radiology
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    • v.84 no.5
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    • pp.1191-1196
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    • 2023
  • Bronchial artery aneurysm (BAA) is a rare disease, and multiple aneurysms of a single bronchial artery are rarer. Regardless of the size of the lesion, it is at risk of rupture and can cause massive hemoptysis or severe pain. We report a rare case of bronchial artery embolization (BAE) of multiple aneurysms of a single bronchial artery. During medical examination, a 64-year-old female was diagnosed with multiple BAAs and endobronchial lesions in the right lower lung on CT 10 years prior to presentation to our hospital. Further evaluation of the lesions was recommended; however, the patient was lost to follow-up. The patient complained of dyspnea and visited our hospital, and the size of the BAA had increased on CT. BAE was done successfully using N-butyl-2-cyanoacrylate and detachable coils. Follow up CT after BAE showed significant decrease in extent of inflammatory lesion in the right lung.

A numerical analysis study on the effects of rock mass anisotropy on tunnel excavation (암반의 이방성이 터널 굴착에 미치는 영향에 대한 수치해석적 연구)

  • Ji-Seok Yun;Sang-Hyeok Shin;Han-Eol Kim;Han-Kyu Yoo
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.26 no.4
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    • pp.327-344
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    • 2024
  • In general tunnel design and analysis, rock masses are often assumed to be isotropic. Under isotropic conditions, material properties are uniform in all directions, leading to a higher evaluation of tunnel stability. However, actual rock masses exhibit anisotropic characteristics due to discontinuities such as joints, bedding planes, and faults, which cause material properties to vary with direction. This anisotropy significantly affects the stress distribution during tunnel excavation, leading to non-uniform deformation and increased risk of damage. Therefore, thorough pre-analysis is essential. This study analyzes the displacement and stress changes occurring during tunnel excavation based on rock anisotropy. A three-dimensional numerical analysis was performed, selecting anisotropy index and dip angles as variables. The results showed that as the anisotropy index increased, the displacement in the tunnel increased, and stress concentration became more pronounced. The maximum displacement and shear stress were observed where the dip planes met the tunnel.

A Comparative Study between Vocational Training Using Virtual Reality and Traditional Training: Focusing on Industrial Cranes (가상현실을 활용한 직업훈련과 전통적인 훈련과의 비교연구: 산업용크레인을 중심으로)

  • Seong-Yeon Mun;Hyun-Jung Oh;Sang-Joon Lee
    • Journal of Practical Engineering Education
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    • v.16 no.4
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    • pp.529-540
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    • 2024
  • In industrial sites, experiential virtual training contents are partially used to replace high-risk and high-cost training, and virtual training contents development is also becoming active along with the increasing demand for non-face-to-face industries. Existing studies mainly focused on quantitative research through surveys, and only measured the change in users' learning commitment. This study attempted to investigate the effect of the combination of theoretical education and virtual training on the improvement of actual job performance in a dual vocational training environment by conducting an experimental study. This study studied whether the combination of theoretical education and virtual training can improve the performance of vocational training in dual vocational training (comparative work and learning) in which companies and schools participate. The results of pre- and post-evaluation of vocational training using traditional vocational training and virtual training contents were compared with 24 vocational training trainees. As a result of the study, it was demonstrated that the outcome of virtual training education was higher than that of traditional vocational training, and the combination of virtual reality-based education was more effective in theoretical education. This study suggests that the virtual training content presents a new paradigm for industrial safety education, and through the interview results of trainees, it was confirmed that virtual training can lead to a change in attitude toward safety beyond just knowledge transfer. This contributes to the prevention of safety accidents in industrial sites and provides important implications for improving the quality of vocational training.

The Effect of Creative Musical on School Adaptation and Self-efficacy of School Maladjusted Adolescents (창작음악극이 학교부적응 청소년의 학교적응 및 자기효능감에 미치는 효과)

  • Kim, Hyun Jung
    • Journal of the International Relations & Interdisciplinary Education
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    • v.4 no.2
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    • pp.1-19
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    • 2024
  • This study examined the effects of creative musical on school adaptation and self-efficacy improvement of school maladjusted adolescents. The subjects of this study were 229 students classified as suspected school maladjustment groups through Wee class counselors and students who were judged as at-risk groups as a result of the emotional behavioral evaluation test conducted by the Office of Education. The study period consisted of 100 minutes per session once a week from May 1st to October 31st, 2023, and a total of 15 sessions were held. To verify the effectiveness, a self-efficacy scale (SES) of Kim A-young (2002)'s school adaptation scale and Sherer et al. (1982) was conducted before and after the creative musical, and the results were analyzed through the corresponding t-test. As a result of the study, the subject's school adaptation (p<.05) and the sub-factors of companionship (p<.05), school class (p<.05), and school rules (p<.05) all increased and were statistically significant after the creative musical compared to before. The subject's self-efficacy (p<.01) and the sub-factors of the study, general self-efficacy (p<.01), and social self-efficacy (p<.05) also increased and were statistically significant after the creative musical compared to before it was conducted. Therefore, this study revealed that creative musicals are effective in improving school adaptation and self-efficacy of school maladjusted adolescents.