• Nuclear Engineering and Technology
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• v.53 no.11
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• pp.3465-3473
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• 2021

For a long time, research into integrated deterministic-probabilistic safety assessment has been continuously conducted to point out and overcome the limitations of classical ET (event tree)/FT (fault tree) based PSA (probabilistic safety assessment). The current paper also attempts to assert the reason why a technical transformation from classical PSA is necessary with a re-interpretation of the categories of risk. In this study, residual risk was classified into interpolating- and extrapolating-censored categories, which represent risks that are difficult to identify through an interpolation or extrapolation of representative scenarios due to potential nonlinearity between hardware and human behaviors intertwined in time and space. The authors hypothesize that such risk can be dealt with only if the classical ETs/FTs are freely relocated, entailing large-scale computation associated with physical models. The functional elements that are favorable to find residual risk were inferred from previous studies. The authors then introduce their under-development enabling techniques, namely DICE (Dynamic Integrated Consequence Evaluation) and DeBATE (Deep learning-Based Accident Trend Estimation). This work can be considered as a preliminary initiative to find the bridging points between deterministic and probabilistic assessments on the pillars of big data technology.

• Journal of Navigation and Port Research
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• v.46 no.5
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• pp.400-408
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• 2022

Maritime transportation is one of the most complicated and hazardous business fileds. Maritime accidents still occur despite several precautions since maritime is exposed to natural factors more than any other industries. In this harsh environment as a part of their job, marine pilots often embark/disembark to/ from vessels and confront life-endangering personal accidents. In the maritime field, several risk assessments are applied. However, all of them could not evaluate occupational accident risk for maritime pilot specifically. This paper performs specific risk analysis using the bow-tie method based on past accident records. This paper aims to qualify root causes and quantify root causes by importance level according to occurrence probability. As a result of analysis, occupational accident occurrence probability is found to be 14%, indicating that accident occurrence rate is significantly high. Hence, the probability of root causes triggering accidents and accident occurrence probability can be ascertained so that preventive measurements can be implemented. Besides theoretical achievement, this paper provides safety awareness to marine pilots, Marine Pilot Organizations, and ship crew who play a key role during marine pilots' transfer.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.4B
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• pp.261-266
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• 2012

In this study, soil environmental impact assessment using risk-based approach was compared with that using concentration-based approach. For this, heavy metal contaminant exposure was characterized in an abandoned mine area. According to the estimated carcinogenic and non-carcinogenic risks, soil ingestion was identified as the most dominant exposure pathway. When contaminant concentrations exceeded the Korean Soil Contamination Warning Standards, their corresponding risk values also exceeded the Total Soil Risk Standard. Even the cases of satisfying the Korean Soil Contamination Warning Standards mostly showed higher risk levels than the Total Soil Risk Standard, re-confirming a more sensitivity of the risk-based assessment than concentration-based assessment. However, the in-depth analysis of the estimated non-carcinogenic risk values revealed a few cases for soil contact pathway showing contaminant concentrations higher than the Korean Soil Contamination Warning Standards although their non-carcinogenic risk values satisfied the level of Hazard Index Standard. The findings from this study support a necessity of shifting policy paradigm from concentration-based approach into risk-based approach for reliable risk assessment in abandoned mine areas, and also suggest a necessity of further fundamental studies regarding risk factors and standards.

• Journal of Radiation Protection and Research
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• v.48 no.2
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• pp.90-99
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• 2023

Background: Quantitative risk assessments should be accompanied by uncertainty analyses of the risk models employed in the calculations. In this study, we aim to develop a computational code named SUMRAY for use in cancer risk projections from radiation exposure taking into account uncertainties. We also aim to make SUMRAY publicly available as a resource for further improvement of risk projection. Materials and Methods: SUMRAY has two versions of code written in R and Python. The risk models used in SUMRAY for all-solid-cancer mortality and incidence were those published in the Life Span Study of a cohort of the atomic bomb survivors in Hiroshima and Nagasaki. The confidence intervals associated with the evaluated risks were derived by propagating the statistical uncertainties in the risk model parameter estimates by the Monte Carlo method. Results and Discussion: SUMRAY was used to calculate the lifetime or time-integrated attributable risks of cancer under an exposure scenario (baseline rates, dose[s], age[s] at exposure, age at the end of follow-up, sex) specified by the user. The results were compared with those calculated using another well-known web-based tool, Radiation Risk Assessment Tool (RadRAT; National Institutes of Health), and showed a reasonable agreement within the estimated confidential interval. Compared with RadRAT, SUMRAY can be used for a wide range of applications, as it allows the risk projection with arbitrarily specified risk models and/or population reference data. Conclusion: The reliabilities of SUMRAY with the present risk-model parameters and their variance-covariance matrices were verified by comparing them with those of the other codes. The SUMRAY code is distributed to the public as an open-source code under the Massachusetts Institute of Technology license.

• The Journal of Health Technology Assessment
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• v.1 no.1
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• pp.22-26
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• 2013

Objectives: Balancing benefits and risks through the drug life cycle has been discussed for many decades. The objective of this study was to review the processes and tools currently proposed for benefit-risk assessment of medicinal drugs. It aimed to establish scientific and efficient drug safety management system based on the synthetic analysis of benefit-risk evidence. Methods: We conducted a review of exiting literatures published by regulatory agencies or initiatives. Not only quantitative methodologies but also qualitative method were compared to understand their key characteristics for the benefit and risk assessment of drugs. Results: Recently, benefit-risk assessments have more structured approaches to decision making as part of regulatory science. Regulatory agencies such as European Medicines Agency, FDA have prepared plans to apply benefit-risk assessment to regulatory decision making. Also many initiatives such as IMI (Innovative Medicine Initiative) have conducted research and published reports about benefit-risk assessment. For benefit-risk assessment, four kinds of methods are necessary. Frameworks such as BRAT (Benefit Risk Action Team) framework, PrOACT-URL provide guidance for the whole process of decision-making. Metrics are measurements of risk benefit. The estimation techniques are methods to synthesis and combine evidences from various sources. The utility survey techniques are necessary to explicit preferences of various outcome from stakeholders. Conclusion: There is the lack of widely accepted, validated model for benefit-risk assessment. Nor there is an agreement among academia, industry, and government on methods for the quantitative valuation. It is also limited by available evidence and underlying assumptions. Nevertheless, benefit-risk assessment is fundamental to improve transparency, consistency and predictability for decision making through the structured systematic approaches.

• Journal of Radiation Protection and Research
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• v.42 no.2
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• pp.130-140
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• 2017

Background: With the need for a domestic level 3 probabilistic safety assessment (PSA), it is essential to develop a Korea-specific code. Health effect assessments study radiation-induced impacts; in particular, long-term health effects are evaluated in terms of cancer risk. The objective of this study was to analyze the latest cancer risk models developed by foreign organizations and to compare the methodology of how they were developed. This paper also provides suggestions regarding the development of Korean cancer risk models. Materials and Methods: A review of cancer risk models was carried out targeting the latest models: the NUREG model (1993), the BEIR VII model (2006), the UNSCEAR model (2006), the ICRP 103 model (2007), and the U.S. EPA model (2011). The methodology of how each model was developed is explained, and the cancer sites, dose and dose rate effectiveness factor (DDREF) and mathematical models are also described in the sections presenting differences among the models. Results and Discussion: The NUREG model was developed by assuming that the risk was proportional to the risk coefficient and dose, while the BEIR VII, UNSCEAR, ICRP, and U.S. EPA models were derived from epidemiological data, principally from Japanese atomic bomb survivors. The risk coefficient does not consider individual characteristics, as the values were calculated in terms of population-averaged cancer risk per unit dose. However, the models derived by epidemiological data are a function of sex, exposure age, and attained age of the exposed individual. Moreover, the methodologies can be used to apply the latest epidemiological data. Therefore, methodologies using epidemiological data should be considered first for developing a Korean cancer risk model, and the cancer sites and DDREF should also be determined based on Korea-specific studies.

• Journal of the Korean Society of Safety
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• v.34 no.4
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• pp.111-118
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• 2019

Accidents occurring due to natural disasters in chemical process facilities where technologies are concentrated can cause secondary damage. The concept of the relationship between natural disasters and highly intensive technologies has evolved into the Natech (Natural Hazards Triggered Technological Disaster) research. Currently, the number of earthquakes is increasing all over the Korean peninsula. To assess the risk of Natech when an earthquake has occurred in South Korea, the Rapid Natech Risk Assessment Tool (RAPID-N) developed by the European Commission's Joint Research Center (EC JRC) was used in the present study. The RAPID-N can be used for Natech risk assessment based on mapping and can be utilized for sufficient preparation for reduction of the effects of Natech accidents. A total of 261 chemical facilities actually existing in Pohang were initially analyzed to select eight facilities and the Pohang earthquake that occurred in 2017 was implemented in the RAPID-N utilizing the shake map. High risk areas were selected through Natech risk assessments for the selected eight work places and countermeasures for the areas were suggested. High risk areas exist depending on the location, since the damage influence ranges could be overlapped and each chemical facility has an independent probability of Natech. Therefore, studies on Natech emergency plans and emergency evacuation routes should be actively conducted considering such high risk areas. The present study was conducted to demonstrate the feasibility of Natech risk assessment in South Korea through the RAPID-N. These findings can be used as a reference material to lay a foundation for Natech risk assessment and related policies in South Korea.

• Journal of Aerospace System Engineering
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• v.16 no.3
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• pp.52-62
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• 2022

In the SORA methodology developed for the operational risk assessment of a specific category of operation of a UAS, the ground and the air risk levels are determined, and a SAIL indicating the level of assurance and integrity for the corresponding risk is assigned, and accordingly, the operational safety level for the proposed operation. Objectives should be demonstrated at an appropriate level of robustness. Because of the nature of the specific category of operation, people on the ground are the first risk subjects to be considered. The resulting ground risk class plays an important role in the allocation of SAIL. In this paper, the impact on SAIL and OSO according to the final risk level and the reduction of the level through the determination of the ground risk level and the application of mitigation measures among risk assessments for specific categories of UAV operation was investigated.

• Earthquakes and Structures
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• v.24 no.4
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• pp.275-288
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• 2023

Based on the crucial role of high-speed railway bridges (HSRBs) in the safety of high-speed railway operations, it is an important approach to mitigate earthquake hazards by proceeding with seismic risk assessments in their whole life. Bridge seismic risk assessment, which usually evaluates the seismic performance of bridges from a probabilistic perspective, provides technical support for bridge risk management. The seismic performance of bridges is greatly affected by the degradation of material properties, therefore, material damage plays a nonnegligible role in the seismic risk assessment of the bridge. The effect of material damage is not considered in most current studies on seismic risk analysis of bridges, nevertheless. To fill the gap in this area, in this paper, a nonlinear dynamic time-history analysis has been carried out by establishing OpenSees finite element model, and a seismic vulnerability analysis is carried out based on the incremental dynamic analysis (IDA) method. On this basis, combined with the site risk analysis, the time-dependent seismic risk analysis of an offshore three-span HSRB in the whole life cycle has been conducted. The results showed that the seismic risk probabilities of both components and system of the bridge increase with the service time, and their seismic risk probabilities increase significantly in the last service period due to the degradation of the material strength, which demonstrates that the impact of durability damage should be considered when evaluating the seismic performance of bridges in the design and service period.

• Transactions of the Korean hydrogen and new energy society
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• v.34 no.5
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• pp.505-513
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• 2023

Hydrogen infrastructure is expanding. High-capacity hydrogen refueling stations offer advantages because they can refuel a variety of light and heavy-duty vehicles, and multi-port refueling technology is developing to reduce charging time for heavy-duty vehicles. In this study, we suggest directions to lower the risk by analyzing the risk factors for each process involved in the installation of a high-capacity multi-port hydrogen refueling station in Changwon city. We conducted both qualitative and quantitative risk assessments of the equipment to evaluate the station. A hazard and operability study was performed for qualitative risk assessment, and PHAST/SAFETI were used for quantitative risk assessment. Quantitative risk assessment was used to calculate the consequence analysis of the facility to ensure secure design prior to station development and to predict individual and societal risks in various scenarios. As a result, the station's risk level was determined to be as low as reasonably practicable.