• Title/Summary/Keyword: Rg5

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Analysis of Ginseng Saponins by HPLC with Photoreduction Fluorescence Detection

  • Kim, Bae-Yuan;Lee, Mi-Young;Cho, Kyung-Hee;Park, Jeong-Hill;Park, Man-Ki
    • Archives of Pharmacal Research
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    • v.15 no.4
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    • pp.328-332
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    • 1992
  • A new high performance liquid chromatographic procedure is described for the analysis of ginseng saponins. Ginseng saponins were separated on Lichrosorb $NH_2$ column and anthraquinone-2, 6-disulfonate (AQDS) solution was added to the column effluent. The effluent was passed through 1.5m-PTFE capillary coiled around 10 W-UV lamp to reduce AQDS to highly fluorescent 9. 10-dihydroxyanthracene-2, 6-disulfonate which was detected by fluorescence detector. The detection limit for the ginsenoside $Rg_1$ by this method was found to be about 350 ng, the dynamic linear range was $10^2$ and the correlation coefficient of the calibration curve was 0.9999.

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Experimental Noise Separation of a Diesel Engine (디젤 엔진소음 (1) ; 실험적 소음 분리기법)

  • 강종민;안기환;박해성;조우흠
    • Journal of KSNVE
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    • v.7 no.5
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    • pp.757-764
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    • 1997
  • The well-developed noise separatrion techniques are applied to the V8 RG8 Diesel engine for the engine noise reduction of a commercial vehicle. For various loads and engine RPM's, the contribution of the combustion oriented noise and the mechanically induced noise was calculated under the small variations of the injection timing. For the given Diesel engine the mechanical noise is dominant for low rpm, and the contribution of the combustion noise becomes greater as the rpm increases. The combustion noise is dominant around 2kHz range or under 50% loading condition.

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Effect of Korean Red Ginseng Polysaccharide on Lipolytic Action of Toxohormone-L from Cancerous Ascites Fluid (고려홍삼 다당체 성분이 암독소 호르몬-L의 체지방 분해작용에 미치는 영향)

  • 이성동;신유정
    • The Korean Journal of Food And Nutrition
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    • v.8 no.2
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    • pp.110-115
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    • 1995
  • This study was devised to observe the inhibitory effects of ethanol treatment precipitate (crude acidic polysaccharide) from Korean red ginseng on a lipolytic action of Toxohormone-L which has been known as lipolytic and anorexigenic factors. Toxohormone-L was obtained by partial purification of the ascites fluid from mice which had been inoculated with sarcoma-180. The yields of crude acidic polysaccharide from Korean red ginseng was 63.5%. In vitro, at the concentration of 500rg /ml, the inhibition rate of lipolysis by the crude acidic polysaccharide of Korean red ginseng was 38.8% and the total inhibitory activity per gram of ginseng material was 4,928 nit. In vivo, the red ginseng polysaccharide(40mg/ml in saline soon.) 16ul/g of body weight was injected to the sarcoma-180 bearing mice once In 3 days until death. The effects against the extension of life span was little but body weight gain of sarcoma-180 bearing mice decreased significantly by administration of Korean red ginseng polysaccharide compared to those of the control group.

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Effects of Ginsenosides on the Glutamate Release and Intracellular Calcium Levels in Cultured Rat Cerabeller Neuronal Cells

  • Oh, Seikwan;Kim, Hack-Seang;Seong, Yeon-Hee
    • Archives of Pharmacal Research
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    • v.18 no.5
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    • pp.295-300
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    • 1995
  • These studies were designed to examine the effects of ginsenosides on glutamate neurotansmission. In primary cultures of rat cerebellar granule cells, ginsenosides (Rb1, Rc did not Rg1, $500\mug/ml$) increased glutamate release which was measured by HPLC. but HPLC, but Re did not shwo an elevation of glutamate release. However, all of these ginsenosides down-regulated N-methyl-D-aspartate (NMDA)-induced glutamate release. Rc strongly increased glutamate release and elevated intracellular clcium concentrations $([Ca_{2+}]_i)$ which was measured by ratio fluorometry with FURA-2AM. These results indicate that ginsenosides have a homeostatic effect on glutamate neurotransmission, and there is a structure-function relationship among the ginsenosides tested.

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경량전철의 전원공급선에 의해 발생되는 자기장 차폐해석

  • Song MK;Oh YS;Kim DH;Joo MS;Rho SK;Lee SJ;Park JD;Chung SG;Jeong RG;Cho HS
    • Proceedings of the KSR Conference
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    • 2003.10c
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    • pp.547-551
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    • 2003
  • This paper presents the magnetic fields shielding properties of the light rail transit which are produced by the ripple-shaped currents in the power lines. To analyze these properties, the equivalent circuit model of the DC power supply system at the light rail transit system was induced by MATLAB-SIMULINK, and with the calculated results of the ripple-shaped currents, the magnetic fields shielding properties of the light rail transit were analyzed. The results are as follows. First The frequency of the ripple-shaped currents is 200[Hz] and its magnitude is 1.5[A]. Second the magnetic fields produced by the ripple-shaped currents of the DC power supply systems are well shielded by the aluminum made body of the light rail transit.

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Hydraulic and Structural Analysis for APR1400 Reactor Vessel Internals against Hydraulic Load Induced by Turbulence

  • Kim, Kyu Hyung;Ko, Do Young;Kim, Tae Soon
    • International Journal of Safety
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    • v.10 no.2
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    • pp.1-5
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    • 2011
  • The structural integrity assessment of APR1400 (Advanced Power Reactor 1400) reactor vessel internals has been being performed referring the US Nuclear Regulatory Commission regulatory guide 1.20 comprehensive vibration assessment program prior to commercial operation. The program is composed of a hydraulic and structural analysis, a vibration measurement, and an inspection. This paper describes the hydraulic and structural analysis on the reactor vessel internals due to hydraulic loads caused by the turbulence of reactor coolant. Three-dimensional models were built for the hydraulic and structural analysis and then hydraulic loads and structural responses were predicted for five analysis cases with CFX and ANSYS respectively. The structural responses show that the APR1400 reactor vessel internals have sufficient structural integrity in comparison with the acceptance criteria.

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Airflow visualization and an interactive method for segmentation of 3D nasal airway (상호작용 기반 3차원 비강 모델 분할 및 가시화)

  • Seo, An-Na;Heo, Go-Eun;Kim, S.K.;Kim, Jee-In
    • Proceedings of the Korean Information Science Society Conference
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    • 2012.06c
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    • pp.320-322
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    • 2012
  • 코 내부의 복잡한 기하학적 형상으로 인해 nasal airway의 분리는 많은 어려움을 겪고 있다. 본 논문은 velocimetry of nasal airflow 와 코 수술 계획을 위하여 3차원 공간에서 nasal airway를 interactive semiautomatic으로 분리하고 시각화하는 방법을 제안한다. 제안하는 방법은 ROI(Region-Of-Interest)와 multi-seed 3d region growing(MS3RG)기법을 적용하여 비강을 분리하며 볼륨렌더링 기법을 이용하여 분리된 영역을 3차원 공간에서 직관적으로 확인 할 수 있다. 또한 분리된 3차원 비강 모델은 유동흐름 실험을 위하여 3차원 프린터를 통해 실제 모형으로 제작 가능하다. 그리하여 CT dataset(512*512*175)을 가지고 매뉴얼 세그멘테이션에서 5시간 정도 걸리던 작업을 반자동 세그멘테이션 방법을 이용할 경우 최대 3분 이내에 분리 작업을 완료할 수 있으며 수치해석 실험 및 물리 실험에 이용할 수 있다.

Assessment of the Strong Motion Duration Criterion of Synthetic Accelerograms (내진설계를 위한 인공지진파 강진지속시간 기준의 평가)

  • Huh, Jung-Won;Jung, Ho-Sub;Kim, Jae-Min;Chung, Yun-Suk
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2006.03a
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    • pp.133-140
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    • 2006
  • This paper addresses a fundamental research subject to complement and improve current domestic design specifications for the strong motion duration criterion and the envelop function of artificial accelerograms that can be applied to the earthquake-proof design of nuclear structures. The criteria for design response spectra and strong motion duration suggested by WRC RG 1.60 and ASCE Standard 4-98 are commonly being used in the profession, and they are first compared with each other and reviewed. By applying 152 real strong earthquake records that are over magnitude of 5 in the rock sites to the strong motion duration criterion in ASCE 4-98, an empirical regression model that predicts the strong motion duration as a function of earthquake magnitude is then developed. Using synthetically generated earthquake time histories for the five cases whose strong motion durations vary from 6 to 15 seconds, a seismic analysis is conducted to identify effects of the strong motion durations on the seismic responses of nuclear structures.

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Antimicrobial Activity and Characteristics of Amblytropis pauciflora Kitagawa Extract (털새동부 추출물의 항균효과 및 특성)

  • 김현수
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.5
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    • pp.993-999
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    • 1998
  • Methanol extract of roots of Amblytropis pauciflora Kitagawa showed the antimicrobial activity to three test strains. Antimicrobial spectra of various extracts of Amblytropis pauciflora Kitagawa were tested against 24 strains of bacteria and fungi. The crude methanol extract inhibited the growth of 12 strains of bacteria and Asp. fumigatus with the exception of yeasts. The properties of the antimicrobial substance were very stable under heat(at 12$0^{\circ}C$), acid(pH 3.0) and alkali(pH 11.0) treatment. Only the root harvested in spring showed the antimicrobial activity. Among the components extracted by butanol, ginseng saponin Rg1 and various saponin-like materials were detected by TLC analysis using a plate of silica gel 60F254. The antimicrobial compound was purified by methanol extraction, activated charcoal column chromatography, Sep-pak(C18) pretreatment and reverse phase HPLC. The purified compound was detected at 13.520 min as a single peak(about 98% purity) through the HPLC analysis.

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