• Journal of Microbiology and Biotechnology
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• v.33 no.4
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• pp.419-429
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• 2023

Ultraviolet C (UV-C, 200-280 nm) light has germicidal properties that inactivate a wide range of pathogenic and spoilage microorganisms. UV-C has been extensively studied as an alternative to thermal decontamination of fruit juices. Recent studies suggest that the efficacy of UV-C irradiation in reducing microorganisms in fruit juices is greatly dependent on the characteristics of the target microorganisms, juice matrices, and parameters of the UV-C treatment procedure, such as equipment and processing. Based on evidence from recent studies, this review describes how the characteristics of target microorganisms (e.g., type of microorganism/strain, acid adaptation, physiological states, single/composite inoculum, spore, etc.) and fruit juice matrices (e.g., UV absorbance, UV transmittance, turbidity, soluble solid content, pH, color, etc.) affect the efficacy of UV-C. We also discuss the influences on UV-C treatment efficacy of parameters, including UV-C light source, reactor conditions (e.g., continuous/batch, size, thickness, volume, diameter, outer case, configuration/arrangement), pumping/flow system conditions (e.g., sample flow rate and pattern, sample residence time, number of cycles), homogenization conditions (e.g., continuous flow/recirculation, stirring, mixing), and cleaning capability of the reactor. The collective facts indicate the immense potential of UV-C irradiation in the fruit juice industry. Existing drawbacks need to be addressed in future studies before the technique is applicable at the industrial scale.

• Journal of TMJ Balancing Medicine
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• v.13 no.1
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• pp.1-12
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• 2023

Objectives: This study was performed to review the research trends in the treatment of anorexia nervosa (AN) in Traditional Chinese Medicine (TCM). Methods: Studies were searched through The China National Knowledge Infrastructure (CNKI) database. The search term for the subject were 'Eating Disorder', and 'Anorexia Nervosa'. Clinical research that conducted TCM treatment for AN patients were included. Studies were analyze according to study design, therapy method, diagnostic criteria, population and intervention. Results: 23 articles were selected. According to study design, studies were classified into two randomized controlled trial (RCT), three single group before-and-after studies, and 18 case reports. According to therapy method, they included 19 herbal medicine studies, two acupuncture treatment studies, and two complex treatment studies. The most common pattern identification was 'liver depression with spleen deficiency' (肝鬱脾虛), and the most used herb was 'Root of Bupleurum falcatum' (柴胡). Most of the studies showed effective results in increasing appetite and weight. Conclusions: The results of our study demonstrate that TCM treatments for AN has been effective in alleviating chief symptoms. However, in terms of evidence-based medicine, lack of RCT on TCM treatments for AN and absence of objective diagnostic criteria in case reports are limitations. Therefore well-designed further clinical studies should be performed based on the results of this study are recommended.

• IMMUNE NETWORK
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• v.20 no.3
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• pp.21.1-21.10
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• 2020

TLRs are pattern recognition receptors (PRRs) whose cytoplasmic signalling domain is similar to that of IL-1. The extracellular domain of TLRs serve as the binding site of pathogen associated molecular patterns. TLRs are found on both plasma and endosomal membranes and they mainly exert their function by activating genes which lead to production of inflammatory factors. The latest TLR to be discovered, TLR10 is a unique TLR which exhibit anti-inflammatory properties. TLR10 is found on the plasma membrane with other TLRs namely TLR1, TLR2, TLR4, TLR5 and TLR6. Studies have revealed that TLR10 is found on the same gene cluster with TLR1 and TLR6 and is also a coreceptor of TLR2. Up to date, TLR10 is the only TLR which exhibit anti-inflammatory property. Previously, TLR10 was thought to be an "orphan receptor" but much recent studies have identified ligands for TLR10. Currently there is no review article on TLR10 that has been published. In this narrative review, we are going to give an account of TLR10, its functions mainly as an anti-inflammatory PRR and its possible applications as a target in therapeutics.

• Journal of Oriental Neuropsychiatry
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• v.26 no.4
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• pp.383-406
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• 2015

Objectives: People with tension-type headache generally take pain relievers, but long term dependency causes problems as well as side effects. The present study aimed to provide clinical evidence of herbal medicine for tension-type headache by systematic review of randomized controlled trials on the effect of herbal medicine for tension-type headache. Methods: Randomized or quasi-randomized controlled trials that verified effects of herbal medicine intervention on patients with tension-type headache were included in the study. A literature search of English, Japanese, Chinese, Korean databases was performed. The selected literature were assessed by Jadad scale and Risk of Bias. Results: Herein, 40 reports were selected from a total of 157. Meta-analyses of 2 trials indicated that the effective rate was significantly higher in the herbal medicine treatment group, as compared to the placebo control (risk ratio: 1.49, 95% confidence interval (CI): 1.23 to 1.80, p<0.0001, I²=0%). Four trials that compared herbal medicine with routine care with routine care only group showed a significantly higher effective rate of benefits for herbal medicine with routine care, as compared to routine care only (RR: 1.57, 95% CI: 1.18 to 2.10, p=0.002, I²=0%). Conclusions: The effective rate was significantly higher than control and adverse events were less in the treatment group. Pattern analysis (辨證) indicated that the studies on wind-fire pattern (風火證) were highest. Yougeun-bang (柔筋方) in prescription and Paeoniae Radix Alba (白芍藥) in medicinal herbs were most used. This finding could be widely utilized in future clinical practice and form the basis for the development of clinical practice guidelines in advance.

• Journal of The Korean Association For Science Education
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• v.44 no.1
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• pp.39-55
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• 2024

This study aimed to examine research trends related to Natural Language Processing (NLP) in science education by analyzing 37 domestic and international documents that utilized NLP techniques in the field of science education from 2011 to September 2023. In particular, the study systematically analyzed the content, focusing on the main application areas of NLP techniques in science education, the role of teachers when utilizing NLP techniques, and a comparison of domestic and international perspectives. The analysis results are as follows: Firstly, it was confirmed that NLP techniques are significantly utilized in formative assessment, automatic scoring, literature review and classification, and pattern extraction in science education. Utilizing NLP in formative assessment allows for real-time analysis of students' learning processes and comprehension, reducing the burden on teachers' lessons and providing accurate, effective feedback to students. In automatic scoring, it contributes to the rapid and precise evaluation of students' responses. In literature review and classification using NLP, it helps to effectively analyze the topics and trends of research related to science education and student reports. It also helps to set future research directions. Utilizing NLP techniques in pattern extraction allows for effective analysis of commonalities or patterns in students' thoughts and responses. Secondly, the introduction of NLP techniques in science education has expanded the role of teachers from mere transmitters of knowledge to leaders who support and facilitate students' learning, requiring teachers to continuously develop their expertise. Thirdly, as domestic research on NLP is focused on literature review and classification, it is necessary to create an environment conducive to the easy collection of text data to diversify NLP research in Korea. Based on these analysis results, the study discussed ways to utilize NLP techniques in science education.

• The Research Journal of the Costume Culture
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• v.17 no.5
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• pp.849-865
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• 2009

This research is a study of fashion design that applied formative features of formal beauty of architecture into clothing design; we focused on Gaudi's architectural style as well as Art Nouveau style that became popular from the end of the 19th century to the beginning of the 20th century. We noted that in general the simple and flat features of cloth impose a limitation on the expression of formal features in clothing design, but a unique diversity of designs can be achieved, evoking a sense of freshness by an ideal combination of flat patterns and draping. The aim of this research is to present a possibility of extending the sphere of design expression by creating three-dimensional clothes with pattern-cutting skills and applications of three-dimensional patterns as well as flat patterns found in Gaudi's works of architecture that are distinguished in curvaceousness and formal beauty. As for the research method, we reviewed previous studies by making a close review of books, papers, the pictures and web sites related to this topic. We made our clothes on the basis of this theoretical consideration. We found the following points. First, by presenting a work of fashion inspired by architectural designs, we realized that formal beauty in architect can become a motive for clothing design in a broad scale by noting the formal images, decoration details, and formative features of architectural works. Second, the characteristic lines of Gaudi's architecture are suitable to be adapted for expressing the detailed lines of decoration in clothes. Third, we can express formative beauty in clothes by highlighting the variation of shapes and lines through various attempts of change in background pattern, even though there is a limitation in the availability of cloth material because we must choose pieces of cloth with right texture and thickness that can be cut and sewn appropriately to express formative beauty. Fourth, we confirmed that it was possible to create unique formative designs by a creative application of both flat and three-dimensional cutting.

• Fashion & Textile Research Journal
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• v.20 no.3
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• pp.343-352
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• 2018

The objective of this study is to investigate the market of fitness compression wear as well as to design an optimal fitness compression wear by analyzing the muscle and movement characteristics of the elderly women in Korea. In this regard, research for functional garments is needed to increase muscle activity of elderly people during physical exercise. Firstly, we investigated the brand, design, size, material, and pattern of fitness wear based on the market survey. Secondly, we identified preference, evaluation items, evaluation method, and pattern design method based on the literature review. Finally, in addition, the motion type, range, angle to improve the muscle strength of the elderly were investigated and the maximum muscle strengths of each motion were analyzed by using 2007 Size Korea data (n = 386). It is also designed for muscle fatigue through exercise and rapid fatigue recovery after exercise. The evaluation methods for fitness compression wear were classified as motor functionality, physiological comfort, pattern and material suitability evaluations. The muscle strength at leg (pushing force) and waist (lifting force) of the ages of 60 to 69 years old showed 239.3 N and 274.5 N, respectively, which were the lowest forces compared to younger age groups. By applying these results to the design process of fitness wear, it is anticipated that the fitness wear will have a proper fit to the body shape of elderly people in South Korea as well as it can increase muscle efficiency to promote physical capability and healthy life for senior people.

• Journal of the Korea Fashion and Costume Design Association
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• v.19 no.2
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• pp.15-28
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• 2017

Today, modern people are exposed to various environmental pollutants such as harmful substances and stress, which can compromise health. Therefore, a healing culture that seeks to enjoy human life based on the healing of body and mind is attracting great attention. The purpose of this study is to develop environmentally friendly natural dyeing considering a healing concept with four elements: color, dye, material, and pattern. The research methods and scope are based on a theoretical review of healing and research on the literature of bedding related to natural dyes, national and international books, the Internet, etc., and naturally dyed bedding. This paper presents actual production research. The results of this study are as follows. First, the elements of color, dyeing, material and pattern were developed through the process of a bedding design development model that applies a healing concept and can be commercialized as a healing bedding product. Second, a healing color proposal was expressed in an intermediate color system of pink, ocher, lavender, and indigo colors for emotional stability, warmth, calmness, comfort and softness. Third, eco-friendly bedding using natural dyes with medicinal efficacy can obtain the healing effect of the natural treatment method, which can aid healthy sleep. Fourth, the pattern used in the bedclothes was a motif of Sarasa embroidery, flower embroidery, ribbon embroidery, and wave quilting motifs to provide psychological stability as a healing concept in the sleeping environment. The natural healing bedding with the healing concept proposed in this study has natural treatment that is beneficial to human health and the development of bedding with natural dyes will lead to an increase of demand for the sleeping environment.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.21 no.4
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• pp.149-160
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• 2010

In 1997, Lavagnino defined four stages of technology trends in libraries; but, he left a question about the fifth stage. Based on literature review, the following; Web technology, open source application, library consortia, digitization, wireless, and social media are the main trends in the fifth stage. Analyzing the job advertisements (ads) dating from 2006 to 2010 in systems librarianship, the analysis showed that there are three patterns. The first pattern is that the title of 'system librarian' is no longer specific to managing only the ILS at many libraries. The second pattern - network management skills - is not highly required in the job ads. And the last pattern - especially academic institutions which have archive or special collection departments - was looking for a systems librarian. In addition, Web technology has evolved as the most required skill according to the advertisements, as well as inter-personal skills in a team environment.

• Health Policy and Management
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• v.25 no.4
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• pp.323-332
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• 2015

Background: Antibiotic resistance has been becoming serious challenge to human beings. Overuse of antibiotics, especially, for infants is concerned, but studies are very few for the prescribing pattern of antibiotic use for infants. This study analyzes prescribing patterns of antibiotics in outpatients of preschool children with acute respiratory tract infections in South Korea. Methods: Data are used from 2011 Health Insurance Review & Assessment Services-pediatric patients sample. Inclusion criteria is outpatient children (0 to 5 years) with top five frequent diseases. Prescription rates are analyzed by types of disease, provider, specialty, region, and ages. Binary or multinomial logit models are used to analyze determinants of providers' prescription pattern. Results: The main findings are as follows. First, distributions of prescription rates are shown as L-shape or M-shape depending on the types of disease. Second, the prescription variation is so large among providers, where providers are polarized as a group with low prescription rates and the other group with high prescription rates, though the shapes are shown diversified across types of disease. Third, prescription rates appear to be lower in pediatrics and higher in ENT (ear-nose-throat). Fourth, broad spectrum antibiotics are widely used among children. Finally, the logit analysis shows similar results with descriptive statistics, but partly different results across types of disease. Conclusion: Antibiotics for respiratory tract infections of infants are used excessively with a large variation among providers, and especially broad spectrum antibiotics are used. The prescription guideline for antibiotics should be provided for each specific disease to reduce antibiotic resistance in the future.