• Korean System Dynamics Review
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• 제16권2호
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• pp.5-32
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• 2015

Last year, a disastrous accident happened on the sea. Car ferry Se-wol which was on its way from In-cheon to Je-ju sank in the middle of the western sea. 304 passengers were drowned at the sea in the accident. There were no passengers who were waiting on board ship rescued in the accident. This study is to review the pattern of decision making in the middle of saving a life, right after Se-wol was about to sink. The starting point of this study is decision making on the rescue by rescue corps with no expert knowledge at the initial stage. When it comes to saving victims, there was no expert on rescue on the sea. Failure in rescue at Se-wol disaster lets us find a vicious circle of positive feedback loop. Experts with no experience act like well-qualified persons. Unqualified persons(leaders) have no expertise. Those who pretend to be expert occupy the important post in the hierarchy. It means we could not accumulate expertise of know-how in rescue division. That's why a vicious circle of positive feedback is formed in areas of disasters. It is necessary to train experts in Government Organizations to weaken the vicious circle of positive feedback.

• The Journal of Internal Korean Medicine
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• 제35권3호
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• pp.332-342
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• 2014

Objectives: This study was investigated in order to analyse the characteristics of recent Chinese medicine treatment of gastric cancer, and provide literature basis for the development of effective therapy of gastric cancer by reviewing Chinese journals. Methods: The literature on Chinese medicine treatment of gastric cancer were collected, analyzed and summarized from the China National Knowledge Infrastructure (CNKI) from 2000 to 2013. Results: Physicians have not shown consistent opinion with the pattern identification of gastric cancer. Recently, traditional Chinese Medicine patent prescriptions have been much used in the treatment of gastric cancer, which is classified into the reinforcement of healthy qi and elimination of the pathogenic factors. Chinese medicine combined with western medicine can improve the immune system and quality of life, while reducing toxic side effects. Conclusions: Further studies on traditional Chinese Medicine are needed to increase the survival rate of gastric cancer and effectiveness of combination therapy with western medicine.

• Quality Improvement in Health Care
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• 제17권1호
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• pp.69-78
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• 2011

Objectives : The purpose of this study was to determine whether the published AMI report card could reduce in-patient mortality, 7-day after discharge mortality, and length of stay (LOS). Methods : Interrupted time-series intervention analysis was used to evaluate the impact of the report card for AMI care quality in November 2005 in terms of risk-adjusted in-patient mortality, risk-adjusted 7-day after discharge mortality, and DRGs case-mix LOS using the claim data of Health Insurance Review and Assessment Service. Results : Public disclosure of AMI care quality decreased risk-adjusted in-patient mortality and DRGs case-mix LOS by 0.00050% per month and 0.042 days per month respectively, however there was no effect on risk-adjusted 7-day after discharge mortality. Patterns of effect of public disclosure on AMI outcomes were a fluctuating pattern on risk-adjusted mortalities and a pulse impact for 1 month on DRGs case-mix LOS. Conclusions : We found the public disclosure of AMI care quality had decreasing effects on risk-adjusted in-patient mortality and DRGs case-mix LOS, but the size of the effect was marginal.

• Asian-Australasian Journal of Animal Sciences
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• 제8권6호
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• pp.533-555
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• 1995

Direct-fed microbials (DFM) have been used to enhance milk production in lactating cattle and to increase feed efficiency and body weight gain in growing ruminants. Primary microorganisms that have been used as DFM for ruminants are fungal cultures including Aspergillus oryzae and Saccharomyces cerevisiae and lactic acid bacteria such as Lactobacillus or Streptococcus. Attempts have been made to determine the basic mechanisms describing beneficial effects of DFM supplements. Various modes of action for DFM have been suggested including : stimulation of ruminal microbial growth, stabilization of ruminal pH, changes in ruminal microbial fermentation pattern, increases in digestibility of nutrients ingested, greater nutrient flow to the small intestine, greater nutrient retention and alleviation of stress, however, these responses have not been observed consistently. Variations in microbial supplements, dosage level, production level and age of the animal, diet and environmental condition or various combinations of the above may partially explain the inconsistencies in response. This review summarizes production responses that have been observed under various conditions with supplemental DFM and also corresponding modification of ruminal fermentation and other changes in the gastrointestinal tract of ruminant animals.

• Journal of Acupuncture Research
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• 제20권3호
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• pp.154-165
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• 2003

Objective : to research the trend of the study related to Bee venom and o establish the hereafter direction for the study on Bee Venom therapy. Methods : We reviewed the domestic papers published last ten years(1992-2001). Results: 1.We have searched 53 papers in 7 journals and the pattern of study was as follow: the experimental studies were 33, the clinical studies were 10 and the reviewed studies were 10. 2. The experimental studies were 2 papers of analysis of Bee Venom, 3 papers of safety assessment, 1 paper on production of antibody against Bee Venom and 26 paper of safety assessment. 3. Bee Venom used in studies was made in Korea, China and U.S.A.. There were differences of component and effect according to the place of production. 4. There were the experimental studies of LD50 in mouse, acute toxicity, local irritation test, antigenicity and pyrogen test of Bee Venom. Conclusions : We need more studies of unification of term about Bee Venom, difference according to the place of production, clinical safety and effects.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제11권2호
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• pp.61-66
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• 1989

Osteopetrosis (Albers-Schonberg disease) is a rare disease characterized by generaized sclerosis of bones, hepatoslenomegaly, pancytopenia, multiple fracture, blindness. The disease shows characteristic radiographic feature and two rather well-defined pattern have been recognized. We experienced a case of osteopetrosis in a 31 year old man, who has had pus discharge and fetid odor after extraction of upper maxillary molar. We made a brief review of literature.

• Herbal Formula Science
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• 제16권2호
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• pp.47-69
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• 2008

Objectives : The purpose of this study is to inspect trends of the papers of osteoporosis in the field of herbal medicines and to establish the future direction for evaluation and development of natural medicines. Methods : We reviewed 80 oriental medicine papers in Korean journals published between 1994 and 2008. Results : There were 6 review, 2 clinical paper, 72 experimental papers and we confirmed that the drugs used in the experiments are almost yang-invigorating drugs which are good for kidney deficiency pattern Conclusions : We found out some of the herbal extracts are very efficacious for osteoporosis. More studies of oriental medicinal herbs are needed for developing anti-osteoporosis drugs with these basic data.

• Toxicological Research
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• 제23권3호
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• pp.197-205
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• 2007

Cancer metastasis is a major determinant of cancer patient mortality. Mounting evidence favors a strong positive role for $TGF-{\beta}$ in human cancer progression. The complex pattern on cross-talk of $TGF-{\beta}$ and the related other signaling pathways is an important area of investigation that will ultimately contribute to understanding of the bifunctional role of $TGF-{\beta}$ in cancer progression. This review summarizes some of the current understanding of $TGF-{\beta}$ signaling with a major focus in its contribution to the tumor cell invasion and metastasis. Five issues are addressed in this review: (1) $TGF-{\beta}$ signaling, (2) $TGF-{\beta}$ and EMT, (3) $TGF-{\beta}$ and MMP, (4) $TGF-{\beta}$ and Ras, and (5) Role of $TGF-{\beta}$ in invasion and metastasis. Due to the bifunctional cellular effects of $TGF-{\beta}$, as a tumor promoter and a tumor suppressor, more precisely defined $TGF-{\beta}$ signaling pathways need to be elucidated. According to the current literature, $TGF-{\beta}$ is clearly a major factor stimulating tumor progression through a complex spectrum of the interplay and cross-talk between various signaling molecules. Understanding the role of $TGF-{\beta}$ in invasion and metastasis will provide valuable information on establishing strategies to manipulate $TGF-{\beta}$ signaling which should be a high priority for the development of anti-metastatic therapeutics.

• Journal of Physiology & Pathology in Korean Medicine
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• 제25권4호
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• pp.708-714
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• 2011

This study was aimed to review the trend of case reports of neuropsychiatry disease. The case reports were collected by retrieving Journal of Oriental Neuropsychiatry and analyzing period were from 1990 to 2010. We analyzed them for publish year, research institution, patients, sorts of diseases, pattern identification diagnosis, instrument, treatment period, sorts of treatments, and treatment with western medicine. We analyzed 142 case reports and there were many kinds of neuropsychiatry diseases and instruments that were evaluated the process. The reserchers used various treatment with oriental medicine. However, the number of case reports have decreased since the year of 2008. Most of the research institutions were university and general oriental medical hospital and the portion of private hospitals was only 2.11%. For the development of practical clinical trial of oriental medicine, we needs more qualifying case report. We hope more reserchers for psychiatry disease of oriental medicine will be interested in the publication of case report and this will serve to produce advance of oriental medicine.

• Journal of Fashion Business
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• 제8권2호
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• pp.116-125
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• 2004

In the history of western costume, women's hairstyle and headdress have been fluently studied but men's headgear has not. To study and manufacture headgear designs and details, which indicate varieties in forms and ornaments, can be utilized for the fashion currently in vogue. Purpose: the purpose of the study is to investigate one of the headgear, the hat in terms of shift in design and manufacturing method, and to study through manufacturing in order to do a literature review by era and to provide information as the source in new design. Study method and scope: Like previously manufactured and presented bonnet of women's headdress or headgear, the hat in the study was manufactured on the basis of literature review and portrait analysis. Target era is from the late 16th century to the early 17th century when the hat was used. The hat to be manufactured was selected by investigating the details such as hair style and hat features using literature. The pattern of the selected hat was analyzed, and velvet, silk, and wool were used as the materials as in the literature. Ornaments used similar things as in the photos.