• Animal cells and systems
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• v.9 no.4
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• pp.181-190
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• 2005

BIRPs (BIR containing Proteins) which contain one to three BIR domains constitute a highly conserved family from yeast to human. BIR domains mediate the interaction of BIRPs with various other proteins. Some of the members acquire a Ring domain which acts as an E3 ubiquitin ligase. The first member of BIRPs identified in the baculovirus was found as an inhibitor of apoptosis and most of the family members in the other species have been recognized to have the same function which bind to and inhibit caspases, thereby suppresses apoptotic cell death. But an increasing number of evidences indicate that BIRPs are involved in various cellular events such as cell division, control of cell cycle, signal transduction, cell migration, innate immunity as well as regulation of apoptosis. In this review, we summarize the structural and functional features of the BIRPs, especially focus on the various functions of BIRPs unrelated to regulation of apoptosis by the recent findings.

• Journal of The Korean Society of Clinical Toxicology
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• v.2 no.1
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• pp.37-40
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• 2004

In emergency department, the clinicians occasionally meet some patients with toxicity caused by ingestion of unknown wild edible greens or herbal agents. Due to there was few quantitative or qualitative studies about the mechanism or clinical features of these materials, it' s hard to approach to the patients and start the initial management in emergency department. Authors experienced the case of poisoning by Scopolia Japonica ingestion. We report this case with review of Scopolia Japonica.

• Journal of Institute of Control, Robotics and Systems
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• v.18 no.3
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• pp.201-207
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• 2012

Jumping is considered as a suitable way for realizing fast locomotion on the ground. As for the issue of developing mobile robots that can jump up and forward enough for accomplishing useful missions, this paper first introduces two types of jumping principles that are found in biological animals or insects. We also present how the principles are applied to several jumping robot examples that include outcomes for the past a few years and also our recent one. Design ideas and features of the robots are explained and compared in order to discuss important issues and guidelines for the design of jumping robots.

• International Commerce and Information Review
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• v.8 no.1
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• pp.337-356
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• 2006

The Korea-US dispute on telecom standards has shown the inability of existing trade rules that can be applicable to standardization policy in telecom services sector. It has entailed plenty of dissenting but unsolved trade issues, including legal jurisdiction over technical standards on telecom services and their compatibility with WTO agreements. Question remains how US will cope with this tricky trade puzzle. This paper points out that Korea-US negotiations on telecom standards have provided US with a momentum to think seriously over the necessity of further rule-setting on telecom standards, and FTAs are the rescue train for US to ride on for that purpose. That is to say, US is taking advantage of FTA as a means to promote its national commercial goals by creating trade rules, which seek to deprive its trading partners of regulatory autonomy in telecom standardization. Based upon the research output, it is very important for Korean government in the upcoming Korea-US FTA negotiations to ensure facilitating public policy objectives in telecom standardization as possible as it can, and not to adopt the provision of international standards in the existing US' FTAs.

• Annals of Clinical Neurophysiology
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• v.17 no.2
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• pp.45-52
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• 2015

The paraproteinemia is a disorder in which a single clone of plasma cells (monoclonal gammopathy) is responsible for the proliferation of monoclonal proteins (M-proteins). Approximately 10% of patients with idiopathic peripheral neuropathy have monoclonal gammopathy. Some M-proteins have the properties of an antibody to the components of peripheral nerve myelin, but the pathophysiological relationship between the neuropathy and the M-protein is often obscure. The relationship between peripheral neuropathy and monoclonal gammopathy requires the appropriate neurological and hematological investigations for precise diagnosis and treatment. In this review, we provide an update on the causal associations between peripheral neuropathy and monoclonal gammopathy as well as characteristics of clinical and electrophysiologic features.

• Journal of the Korea Safety Management & Science
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• v.3 no.2
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• pp.33-49
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• 2001

This article is concerned with various aspects of establishing the global standard for occupational safety and health management system (OHSMS). The notion, main features, and brief history of the OHSMS are presented. The OHSAS 18000, its assets and liabilities, are reviewed as a prototype of the global standard. It is also addressed the possibility of combining ISO 9000(quality management system), 14000(environmental management system) and the OHSMS into the integrated management system (IMS) as a whole. The concepts of internal and external customers are presented to explain why the environment, safety and health should be incorporated into the notion of total quality 'Participation of the members' and 'standardization of the 4Ms (Man, Machine, Materials and Method)'are emphasized as the major enablers of the IMS. Finally, the industrial, academic and governmental roles are discussed for developing the IMS and setting it down into the Korean industries.

• KSCI Review
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• v.15 no.1
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• pp.185-190
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• 2007

An image retrieval system is a piece of software that searches identical or similar images based on various image-specific features. This paper proposes a trademark image retrieval system that uses image colors and forms. In the proposed system, input images are segmented into several other regions, and color distribution histograms for different regions are extracted for use as color information. The proposed system uses form information through the preprocessing process such as boundary surface extraction, centroid extraction, angular sampling and, and through calculating the sums of the distances between the centroid and the boundary surfaces, standard deviations, and the ratios between long and short axes. Like this, the color and form information extracted is used to perform retrieval through measuring similarity.

• Tuberculosis and Respiratory Diseases
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• v.43 no.2
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• pp.262-266
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• 1996

Intradural extramedullary spinal metastasis from systemic tumor is extremely rare but epidural extramedullary cord tumor metastasis from the lung is relatively common. A 57 year-old male patient was admitted to department of internal medicine and neurosurgery in Chonbuk National University Hospital because of coughing, low back pain radiate to the right great toe, and numbness of the right calf area. Spinal MRI scan revealed round oval shaped mass lesion on just below the level of the conus medullaris. Authors present the clinical, histologic, radiologic features of spinal intradural metastatic tumor and operative total removal followed by chemothrapy with an extensive review of literatures.

• STI Policy Review
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• v.3 no.1
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• pp.139-161
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• 2012

The United States National Innovation system has many distinctive aspects and its government research institutes (GRI's) play a variety of important roles within the overall system. This paper reviews issues pertaining to U.S. GRI's but within the broader concept of US science and technology policy. After presenting an overview of the GRI's in this broader context, the paper presents a brief historical analysis of changes in the roles and deployment of U.S. GRI's. After identifying unique features of GRI's (ones that separate the U.S. GRI's from other nations) the paper concludes by identifying the ways in which the U.S. experience may be relevant to other nations such as Korea. The lessons include the competition-cooperation with large-scale and multidisciplinary university research centers, the use of GRI's to promote sharing and efficiencies in fundamental scientific equipment and resources, and the ability of GRI's to accelerate the development of science and technology.

• Molecules and Cells
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• v.38 no.10
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• pp.836-842
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• 2015

G protein-coupled receptors (GPCRs) constitute the largest and the most physiologically important membrane protein family that recognizes a variety of environmental stimuli, and are drug targets in the treatment of numerous diseases. Recent progress on GPCR structural studies shed light on molecular mechanisms of GPCR ligand recognition, activation and allosteric modulation, as well as structural basis of GPCR dimerization. In this review, we will discuss the structural features of GPCRs and structural insights of different aspects of GPCR biological functions.