• Journal of the Korean Society of Costume
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• v.59 no.6
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• pp.140-155
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• 2009

This study tries to find out the special twine technique of flat string and refers to historical documents, records, artifacts of excavated articles, and real materials. In Japan weaved cloth is called Jomul or Jonue and these methods were brought to Japan from Korea during Aska Period(645${\sim}$710) and Nara Period(710${\sim}$794). Among those knot methods, the 1/1 knot was written as a Shillajo on a documentary record at Heian Period, Engisik, and Samdaesillok which is a historic document from King Saiya to King Gowooko(858${\sim}$887). Also 2/2 knot weaving was recorded as Goryeojo that the technique originated for a long time in Japan. During the Joseon Dynasty, Gunmok was written as Dahoi, and Gwangdahoe, which means wide and flat Gunmok, was the name of Dae(Belt). The frame for the twine Gwangdahoe is no longer in Korea, but only can be found in Japan as a Goraiwoochi loom for Shillajo and Goryeojo from Korea. There are currently artifacts by the techniques of Shillajo and Goryeojo that were excavated in 15${\sim}$17C in Korea. Therefore this study was looked into the artifacts from 6${\sim}$8C in $Sh{\"{O}}so$-in, and the features of Dae (Belt) weaved by Shillajo and Goryeojo case method. Gwangdahoe excavated artifacts in the mid Jeosun Dynasty was restored by the process of Goryeojo weaving method.

• Korean Journal of Head & Neck Oncology
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• v.31 no.2
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• pp.6-10
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• 2015

Background and Objective : Papillary thyroid microcarcinoma(PTMC) is known as slow growing cancer with good prognosis. However, extrathyroidal extension may increase the risk of cervical lymph node metastasis and local invasion to surrounding structures. The aim of this study was to assess the characteristic features of the tumor invading the posterior thyroid capsule. Material and Methods : We made a retrospective review of 123 PTMC patients with thyroid capsule invasion, pathologically staged as T3 or T4. 74 patients (60.2%) had invasion to posterior thyroid capsule (group A) while 49 patients (39.8%) had invasion to-anterior thyroid capsule or anterior wall of trachea (group B). We assessed the clinicopathologic factors of the patients according to the location of capsular invasion of PTMC. Results : There was no difference regarding age, gender, T and N classification and incidence of lymph node metastasis between two groups. Local invasion rate to recurrent laryngeal nerve was 6.8% in patients with posterior thyroid capsule invasion, while the incidence was zero in those with capsular invasion to other locations Conclusion : Increased risk of local invasion to the recurrent laryngeal nerve should be considered in patients with PTMC presenting invasion of the posterior capsule.

• Journal of Life Science
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• v.14 no.6 s.67
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• pp.1028-1039
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• 2004

During the past 65 million years, Alu sequences have been amplified through RNA-polymerase IIIderived transcripts, and have reached the copy number of about 1.4 million in primate genomes. They are the largest family among mobile genetic elements in human genome and consist of ten percent of the human genome. Alu sequences are thought to be functionless genetically, but many researchers have proved new function and disease implication. Alu elements make the genome insertional mutation, Alu-mediated recombination events, and unexpected splicing site and change gene structures, protein sequences, splicing motifs and expression patterns. In this review, the structure and origin of Alu, consensus sequences of Alu subfamilies, evolution and distribution of Alu, and their related diseases were described. We also indicated new research direction of Alu elements in relation to evolution and disease.

• The Korean Journal of Cytopathology
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• v.9 no.2
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• pp.213-219
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• 1998

Glycogen-rich clear ceil carcinoma of the breast is an unusual variant of carcinoma with a recorded incidence of $1.4{\sim}3%$ of breast carcinomas. The cytologic characteristics have not been well described. We report two cases of glycogen-rich clear cell carcinoma with corresponding fine needle aspiration(FNA) cytologic findings and compare them to infiltrating ductal carcinoma and other clear ceil malignancies with a review of literature. One was a 62-year-old woman exhibiting a palpable mass of the right breast. The smears showed atypical tight cell clusters and individually scattered single cells containing leanly or clear abundant cytoplasm with well defined cytoplasmic margins. Mild to moderate nuclear pleomorphism and a prominent nucleolus were present. The other was a 42-year-old woman who was admitted with a right breast mass. The smears showed moderately cellular, tightly cohesive tumor cells. The cytoplasmic outline was generally well demarcated. The tumor cells Contained foamy to clear abundant cytoplasm with large and small vacuoles. The nuclear pleomorphism was marked. Both tumors resected by modified radical mastectomy, were diagnosed as glycogen-rich clear cell carcinoma. Histologically, the clear cell nature of tumor cells were not characteristic enough to predict this type of the tumor. Some cytologic features can be distinguished other clear cell breast cancer from glycogen-rich carcinoma. Recognition of these unusual patterns in a breast FNAC should raise the suspicion of a clear cell carcinoma including glycogen-rich subtype. Cytological localization of glycogen using PAS and D-PAS staining may permit the correct Identification and differential diagnosis of this tumor.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.965-975
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• 2004

The writer reviewed on Chojop and came to conclusions as follows. Symptoms of Chojop is appeared digestive ailment such as belching, nausea, regurgitation of acid, stomachache etc., if being serious, felt oppressed with palpitating in chest and uneasiness at times. In Dangaesimbub written by Chujinhyung, the causes of Chojop were mainly regarded as phlegmatic fire(痰火) and suggested the way of treatment. The causes of Chojop are movable fire with phlegm, insufficiency of blood caused by thinking to excess, and Shinyanghohan(腎陽虛汗) that is piled cold phlegm by voidance and coldness of Renal Yang, but the main cause is brought to a conclusion as phlegmatic fire. The phlegmatic fire is come from being in discord with the spleen and the stomach, or from in harmony between vigor and blood according to essence and vital energy which are disturbed by combined feelings. That is caused by disharmony between inner and outer conditions according to individuals. The distinctive features in shapes of Chojop are revealed to shapes such as manlike woman, womanlike man, wearing darkish or reddish color between two eyebrows, being almond eyed, strong eyebrows, being sunk the upper part of the nose bridge, lots of facial blots, Dam-body, Ki type, Shin type, Birds group, and Yangmyung type. The doctors can prescribe Whadamchungwhatang to Yangmyung type, Yanghyulsamul-tang for patients with strong eyebrows so flourishing blood and vigor, Hyangsapyungwuisan for patients belong to Birds group, Soshikchungul-tang for Ki type, and Palmiwhan for man belonged to Bangkwang-body with voidance and coldness of Renal Yang chiefly.

• Archives of Plastic Surgery
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• v.43 no.1
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• pp.59-65
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• 2016

Background In East Asia, the foot is the most common site of cutaneous melanoma. The purpose of this study was to investigate the differences between cutaneous melanoma of the foot and melanomas of other sites. Methods We studied 52 patients who underwent surgical treatment for cutaneous melanoma of the foot from September 2000 to January 2015. Through a retrospective review of their medical records, we collected data relating to their sex, age, histopathological subtype, Clark level, tumor thickness, lymph node involvement, stage, and survival rate, and we compared these parameters to those of 61 patients treated for melanoma of other sites. Moreover, we analyzed the surgical procedures, complications, and mortality rates associated with cutaneous melanoma on various parts of the foot. Results Melanoma of the foot differed from other melanomas only in the histopathological subtype. Other clinical features, including survival rate, did not differ significantly between the two groups heel was the most common site of melanoma of the foot (22 cases, 42.3%). The method of reconstruction varied depending on the region involved. Conclusions A comparison of melanoma of the foot to other melanomas showed that melanoma of the foot was associated with a significantly different distribution of histological subtypes. Consistent with previous findings, we found that the acral lentiginous subtype was the most common among melanomas of the foot. Furthermore, in contrast with previous studies, we did not find a worse prognosis or lower survival rate for melanoma of the foot in comparison with other melanomas.

• Pediatric Infection and Vaccine
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• v.8 no.2
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• pp.222-228
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• 2001

The frequency and severity of intestinal tuberculosis are decreased due to socioeconomic development, pasteurization of milk and more effective anti-tuberculous chemotherapy. But in recent year, HIV-infected patients are known to be at high risk of developing tuberculosis. The pathogenesis of intestinal tuberculosis is dependent on a immune state and nutritional status of the patient, the tuberculosis amount of sputum and tuberculosis toxicity. The diagnosis of intestinal tuberculosis is usually difficult because of non-specific clinical features and radiological signs. Chronic diarrhea in intestinal tuberculosis is able to produce a malnutrition, marasmus, kwashiorkor or the combined form. The treatment is anti-tuberculous chemotherapy for 12~24 months, but operation should be considered to intestinal perforation, obstruction, fistula formation and massive bleeding. The study about kwashiorkor in intestinal tuberculosis is rare in recent years, we should remind that tuberculosis is still prevalent disease in Korea. We report a ten year-old boy with ileocecal tuberculosis who presented with kwashiorkor, severe malnutrition with review of literature.

• Journal of Trauma and Injury
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• v.24 no.2
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• pp.129-135
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• 2011

Purpose: During August 2010, a natural gas fuel cylinder on a bus exploded in downtown Seoul, injuring 20 citizens. This kind of blast injury has never been reported in Korea before. Thus, the goal of this study was to review the clinical features of these victims to help physicians manage similar cases and to understand the risk factors associated with blast injuries in everyday life. Methods: Twenty (20) victims who visited nearby emergency departments, and 3 peoples left hospital without care. Seventeen (17) victims were included in this study, and the following factors were investigated: age, sex, type of hospital, diagnosis of injury, injury mechanism, position of victim (in-bus/out of bus), classification of injury severity with START (simple triage and rapid treatment), and classification of injury according to the mechanism of the blast injury. Results: The victims included 8 males (47%), 9 females (53%). The mean age was $37.5{\pm}12$. Thirteen (13) victims were transferred to two tertiary hospitals, and 4 were transferred to two secondary hospitals. The types of injury were 3 fractures, 2 ligaments injuries, 6 contusions, 4 abrasions, and 3 open wounds (one of them was combined fracture). According to START classification, 17 victims were 1 immediate, 11 minor, 5 delayed, and no death. Classifications according to the mechanism of the blast injury were 1 primary injury, 6 secondary injuries (2 of them combined other mechanism), 3 tertiary injuries and 9 quaternary injuries. Conclusion: Trauma care physicians should be familiar with not only the specific types of injuries from blast accidents, but also the potential accidents that may occur in public facilities.

• The Korean Journal of Community Living Science
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• v.18 no.1
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• pp.189-204
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• 2007

This review was to suey the status of agricultural diseases, injuries and accidents among England, the USA, France, Japan, and Korea. For this purpose, detailed research objectives were to analyze the current national status of agricultural diseases, injuries and accidents in Korea and four foreign countries. To do so, related literature such as books, theses, articles, and web documents were collected and analyzed. The implications for industry and agricultural safety and health, diseases, occupational injuries and accidents of farmers thereby derived were as follows: 1) efforts on unifying administrative systems, 2) special support and management systems focusing on neglected subjects, 3) committees for collecting opinions and suggesting alternative policies on the behalf of various financiers, 4) aligned strategies including vision, goals, and long-term plans about national safety and health projects, 5) development of supporting systems considering the features of agriculture, 6) systematized national surveys about occupational injuries and accidents for basic statistics and national studies, 7) active prevention efforts against occupational injuries and accidents, and 8) specialized funds for the safety and health of farmers.

• Journal of Pharmaceutical Investigation
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• v.40 no.spc
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• pp.75-82
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• 2010

Specific diseases like cancer and acquired immune deficiency syndrome (AIDS) occur at various organs including lymphatics and spread through lymphatic system. Thus, if therapeutic agents for such diseases are more distributed or targeted to lymphatic system, we can obtain several advantages like reduction of systemic side effect and increase of efficacy. For these reasons, much interest has been focused on the nature of lymphatics and a lot of studies for lymphatic delivery of drugs have been carried out. Because lymphatics consist of single layer endothelium and have high permeability compared with blood capillaries, especially, the studies using nano-sized carriers have been performed. Polymeric nano-particle, liposome, and lipid-based vehicle have been adopted for lymphatic delivery as carriers. According to the administration route and the kind of carrier, the extent of lymphatic delivery efficiency of nano-sized carriers has been changed and influenced by several factors such as size, charge, hydrophobicity and surface feature of carrier. In this review, we summarized the key factors which affect lymphatic uptake and the major features of carriers for achieving the lymphatic delivery. Lymphatic delivery of drug using nano-sized carriers has many fold improved ability of lymphatic delivery compared with that of conventional dosage forms, but it has not shown whole lymph selectivity yet. Even though nano-sized carriers still have the potential and worth to study as lymphatic drug delivery technology as before, full understanding of delivery mechanism and influencing factors, and setting of pharmacokinetic model are required for more ideal lymphatic delivery of drug.