• Journal of Life Science
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• v.27 no.12
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• pp.1515-1522
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• 2017

Most people have a desire to live longer. According to ancient Chinese and Korean mythology, Dongfang Shuo (Dongbang Sahk) lived for 18,000 years. According to a WHO report, the average longevity of humans has extended from 50-odd years in the 1960s to 75-85 years in 2016. Parabiosis, the joining to circulatory systems of two animals, was described as early as the 1860s. It provides a powerful experimental model to investigate the effects of one animal on its partner animal in vivo. Research on reverse aging is an immensely popular in parabiosis studies. In this review, the origin of the parabiosis model and important historical findings based on parabiosis models are presented. Surprising and debated discoveries in aging research are also introduced. Using heterochronic parabiosis of connecting circulatory systems of a young mouse and old mouse, various groups claim to have identified a reverse aging factor, growth differentiation factor 11 (GDF11), which was significantly reduced in blood of old mice. Although the potential existence of any one factor or factors that could reverse aging remains to be confirmed, studies have shown that the parabiosis model is powerful enough to detect reverse aging factors.

• Journal of the Korean Operations Research and Management Science Society
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• v.42 no.1
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• pp.29-41
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• 2017

Korea is expected to become a super-aged society by 2050. Given an aging population and the increasing pressure for the early retirement, a sufficient social safety net for elderly population becomes important. The Korean government introduced public reverse mortgage program in 2007, which is a product for aging seniors and the elderly, The number of reverse mortgage subscribers has also steadily grown. The demand continues to grow, but the reverse mortgage over a long period of time is a highly uncertain and risky product in the position of guarantee or lending institution. Thus, suitable demand prediction of the reverse mortgage subscribers is necessary for stable and sustainable operation. This study uses a Bass diffusion model to forecast the long-term demand for reverse mortgage and provides insight into reverse mortgage by forecasting demand for stability and substantiality of the loan product. We represent the projections of new subscribers on the basis of the data obtained from Korea Housing Finance Corporation. Results show that potential market size of Korean reverse mortgage reaches approximately 760,000-1,160,000 households by 2020. We validate the results by comparing the estimate of the cumulative number of subscribers with that found in literature.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.20 no.3
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• pp.197-201
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• 2007

The accelerated aging test equipment which is possible to apply voltage and temperature at the same time, is fabricated to predict lifetime of high capacity thyristor in short time. The variations of the forward/reverse breakdown voltage and the leakage current are investigated as an aging diagnostic tool. Lifetimes of the devices which are predicted from the reverse breakdown voltage with an accelerated aging time, have shown 3-15 years.

• BMB Reports
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• v.47 no.1
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• pp.8-14
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• 2014

Telomerase plays a pivotal role in the pathology of aging and cancer by maintaining genome integrity, controlling cell proliferation, and regulating tissue homeostasis. Telomerase is essentially composed of an RNA component, Telomerase RNA or TERC, which serves as a template for telomeric DNA synthesis, and a catalytic subunit, telomerase reverse transcriptase (TERT). The canonical function of TERT is the synthesis of telomeric DNA repeats, and the maintenance of telomere length. However, accumulating evidence indicates that TERT may also have some fundamental functions that are independent of its enzymatic activity. Among these telomere-independent activities of hTERT, the role of hTERT in gene transcription has been investigated in detail. Transcriptional regulation is a fundamental process in biological systems. Several studies have shown a direct involvement of hTERT in gene transcription. This mini-review will focus on the role of hTERT in gene transcription regulation, and discuss its possible mechanisms.

• Journal of the Korean Society of Industry Convergence
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• v.25 no.6_2
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• pp.1119-1125
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• 2022

The depletion of resources and waste disposal caused by the continuous development of industry have emphasized the need to reduce consumption and production, recycle and reuse, and the importance of remanufacturing has increased in recent years. The spindle part of the aging planner miller, which is currently being remanufactured, is one of the factors that has the greatest impact on the performance of the machine tool. When designing the spindle part of the spindle shaft, there are considerations such as the configuration size bearing performance of the main shaft, but the diameter of the main shaft, the dangerous speed bearing, and the arrangement that affect the machining accuracy should be basically considered. As such, various studies have been conducted on the design of machine tool spindle spindles, but research on the reverse engineering of existing aging machine tool spindle spindles is poor. Reverse engineering is designing in the direction of improving performance by extracting specifications from already finished products, and first scanning the reverse engineered object through a 3D scanner, 3D modeling is performed based on the collected data, and then the process of deriving improvement plans by reverberating to improve performance by identifying wear and damage conditions is followed. Therefore, in this study, the purpose of this study is to provide data on reverse engineering by deriving improvement plans through optimal design for the bearing position of the aging planar Miller spindle spindle using central composite programming.

• Journal of Korean Institute of Industrial Engineers
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• v.40 no.2
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• pp.205-214
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• 2014

As a result of the rapid economic growth and birth control policy, China is experiencing low fertility rates and increasing life expectancy, which makes Chinese population aging very quickly and unprepared for their retired life. The reverse mortgage may be an attractive option for the elderly because it is a loan against a house that they do not have to pay back as long as they live there. In this paper, in order to introduce the reverse mortgage scheme in China the factors that could influence the demand of reverse mortgage are reviewed and the Chinese market environment is analyzed. Then the principal component analysis is performed in order to recommend the regions or cities that have higher potential for successful implementation of a reverse mortgage than any other ones in China.

• Journal of the Korean Society for Heat Treatment
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• v.6 no.4
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• pp.213-222
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• 1993

This research was performed to investigate the transformation behavior and shape memory effect of Cu-13.5Al-4.5Ni(wt%) alloy with various aging temperature and time. The results obtained in this study are as follows: Transformation temperature was very increased when aging temperature is at $250^{\circ}C$. The variation of transformation temperature in first reverse transformation cycle and second was very significant, but there was little difference in case of 2nd and 3rd. Transformation temperature at various aging temperature was increased with increasing of aging temperature and time. Microvickers hardness was increased with increasing of aging temperature and time. It was found that ${\alpha}$ and ${\gamma}_2$ phase were created by aging of long time at high temperature.

• Journal of the Korean housing association
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• v.16 no.5
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• pp.49-56
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• 2005

This study will focus on status and structure of Japanese public reverse mortgage that has been changed since 1980. Especially, on newly introduced long-term supporting system for living fund after 2003. Private housing construction companies studied preceding cases of real estate products with reverse mortgage theory and also induced learning point from the change of Japanese public reverse mortgage market. From this on the purpose of this study is suggesting a better plan for successful reverse mortgage introduction in Korea. The data and articles of Japanese reverse mortgage are used for this study, also reverse mortgage related data are collected from web-site and research reports from the inside and outside of the country. From the total postal survey in September, 2004, the system contents after Year 2003 are described here. As described above, reverse mortgage is a way to support public social pension system and expected to play an important role as an assisting method for stable housing and supporting living cost to the aged. Eventually, it is necessary to find a way for introducing a public reverse mortgage as a welfare system for low income people.

• Journal of Korean Society of Rural Planning
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• v.15 no.2
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• pp.69-80
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• 2009

The purpose of this paper is to estimate the regional economic impact of reverse mortgage system based on farmer's net asset of house and farmland together. The regional economic impact was estimated by using inter-regional input-output model. Major findings are as follows: 1) The result of input-output analysis shows that 49,130 million won of production effect, 20,040 million won of value added effect, and 24,759 number of employment effect, 2) Since the result shows that the elderly spend most of the reverse mortgage money for their living expenses, it seems necessary to adopt net asset based reverse mortgage system to improve and stabilize farmers' living conditions and regional economy.

• The Journal of Asian Finance, Economics and Business
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• v.1 no.4
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• pp.5-13
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• 2014

This study contributes to addressing the problem of an aging population by providing important information that determines feasible monthly payments for the clients of Chinese reverse mortgage products and by promoting the implementation of reverse mortgages in China. The variables used in this study include mean values obtained from time series data, of the rate of increase of housing prices, and the probability value, interest rate, and mortality rate obtained through the geometric Brownian motion (GBM). For mortality rates, China Life Insurance female mortality rates (2000-2003) were used. This study aims to apply the main variables that affect reverse mortgage products in a monthly payment model based on Chinese financial market conditions, and determine loan values. In this study, Shanghai's reverse mortgage monthly payments, by age levels, were calculated through the loan-to-value (LTV) and payment (PMT) methods to evaluate the value of the reverse mortgages. Based on the optimal combination of the three factors of payment amount, loan interest rates, and the level of acceptance of prices, efforts must be made to extract the best value for the elderly. Only in this way can the interests of both lenders and borrowers be protected, by increasing the market share and economies of scale of the reverse mortgage industry and effectively improving the living standards of the elderly.