• Title/Summary/Keyword: Return of function

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Mathematical Modeling and Simulation on the Control of Heart rate by Baroreceptor Control System in the Cardiovascular System (심혈관 시스템의 압수용체에 의한 심박동 제어의 수학적 모델링 및 시뮬레이션)

  • Choi, B.C.;Lee, S.J.;Eom, S.H.;Nam, G.K.;Lee, Y.W.;Jun, K.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.80-85
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    • 1996
  • The various function of the cardiovascular system(CVS) and the dynamic characteristics on each part of human body can be acquired in the electric analog circuit model. According to the performed outcome by other researchers, viscos resistance, flow inertia, and vascular compliance in the CVS are analogous to resister, inductor, and capacitor in electric circuit, so the CVS models were represented by the electric circuit models. these approaches were to propose the suitable models interest part of body and to simulate the various characteristics on the CVS. In this paper, the electric circuit model considering the characteristics of morphologic structure is represented, the parameter values of model is sotted up, and the dynamic characteristics of the the CVS is simulated using VisSim, one of the simulation tools. The observed simulation results are similar to the cardiovascular functions of nomal adults who have no heart failure. Besides, the simulation is operated to observe the pathophysiological abnomal symptoms(for example, bleeding within a certain period). The controller by baroreceptor, which is one of controllers to control the CVS, is appended in the model. and the dynamic response characteristics and the procedure to return normal state is observed in simulation when the bleeding last within a certain period.

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Revenge of the Flesh: The Return of Sexual and Racial Otherness in Faulkner's Absalom, Absalom! ('육체의 복수' -포크너의 『압살롬, 압살롬!』에 나타난 성적, 인종적 타자의 귀환)

  • Kwon, Jieun
    • Journal of English Language & Literature
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    • v.58 no.4
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    • pp.701-721
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    • 2012
  • This paper aims to revisit William Faulkner's Absalom, Absalom! by focusing on the corporeal body and its role in dismantling the Southern ideology of white patriarchy. The latter, which is represented by Thomas Sutpen and his attempt to establish a white male dynasty, is a symbolic space in which the corporeal body turns into a symbolic one through the process of inscribing social ideologies on it. However, this symbolic space is also a contending site between the two bodies. The symbolic body of Sutpen cannot entirely erase its corporeal traces, and therefore the corporeal body, which is buried but nonetheless existent, threatens to undermine rules and premises of the symbolic order. Given that, this paper approaches Faulkner's critique of the Southern white patriarchal ideology from the tension that the corporeal body and the symbolic body create. The 'flesh' roughly corresponds to racial and sexual otherness, namely black flesh and the homoerotic desire of male body. Although they-as the matter of race and that of gender - function in different levels of signification, they still share a common purpose in revealing the logical paradox within Sutpen's symbolic order. The idea of pure whiteness that Sutpen subscribes to is a concept that prerequisites the existence of blackness. Likewise, his idea of male homosociality based upon patriarchal legacy stands precariously on the verge of disintegrating into homoetoricism. As internal otherness that Sutpen's symbolic order cannot fully incorporate, the corporeal body functions to indicate the limitation of Sutpen's Design and its body-signification process.

MEDU-Net+: a novel improved U-Net based on multi-scale encoder-decoder for medical image segmentation

  • Zhenzhen Yang;Xue Sun;Yongpeng, Yang;Xinyi Wu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.18 no.7
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    • pp.1706-1725
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    • 2024
  • The unique U-shaped structure of U-Net network makes it achieve good performance in image segmentation. This network is a lightweight network with a small number of parameters for small image segmentation datasets. However, when the medical image to be segmented contains a lot of detailed information, the segmentation results cannot fully meet the actual requirements. In order to achieve higher accuracy of medical image segmentation, a novel improved U-Net network architecture called multi-scale encoder-decoder U-Net+ (MEDU-Net+) is proposed in this paper. We design the GoogLeNet for achieving more information at the encoder of the proposed MEDU-Net+, and present the multi-scale feature extraction for fusing semantic information of different scales in the encoder and decoder. Meanwhile, we also introduce the layer-by-layer skip connection to connect the information of each layer, so that there is no need to encode the last layer and return the information. The proposed MEDU-Net+ divides the unknown depth network into each part of deconvolution layer to replace the direct connection of the encoder and decoder in U-Net. In addition, a new combined loss function is proposed to extract more edge information by combining the advantages of the generalized dice and the focal loss functions. Finally, we validate our proposed MEDU-Net+ MEDU-Net+ and other classic medical image segmentation networks on three medical image datasets. The experimental results show that our proposed MEDU-Net+ has prominent superior performance compared with other medical image segmentation networks.

Effect of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) on Neutropenia Occuring during Radiotherapy (GM-CSF가 방사선 치료시 발생한 호중구감소증에 미치는 영향)

  • Jang Ji Young;Choi Ihl Bohng;Chung Su Mi;Kim In Ah;Kay Chul Seong;Kim Chun Chu;Shin Kyung Sub
    • Radiation Oncology Journal
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    • v.13 no.1
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    • pp.79-85
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    • 1995
  • Purpose : To assess the efficacy of recombinant human granulocyte-macrophage colony-stimulating factor(GM-CSF) in the neutropenia by radiotherapy. Materials and Methods : Eleven patients with various solid tumor were treated with a daily subcutaneous dose of GM-CSF(3-7microgram/kg) for 5days during the radiotherapy. Before and during the course of the study all the patients were monitored by the recording of physical examination, the complete blood count with differential and reticulocyte count and liver function test. Eight patients received prior or concurrent chemotherapy. Results : In 10 patients, the neutrophilic nadir was significantly elevated and the lenght of time that Patients had a neutrophil count below $10^3/mm^3$ a threshold known to be critical to acquiring infective complications was shortened following GM-CSF injection. A significant rise (two fold or greater) of neutrophil count was seen in 10 of 11 patients. In most patients, discontinuation of GM-CSF resulted in a prompt return of granulocyte counts toward baseline. However the neutrophil count remained elevated over $10^3/mm^3$ during radiation therapy, and radiotherapy delays were avoided. Other peripheral blood components including monocytes and platelets also increased after GM-CSF treatment. No significant toxicity was encountered with subcutaneous GM-CSF treatment. Conclusion : GM-CSF was well tolerated by subcutaneous route and induced improvement in the neutropenia caused by radiotherapy.

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Foreign Language Education of Korean Peninsula: Insights from Nogeldae (『노걸대』 분석을 통해서 바라본 우리 반도의 외국어 교육)

  • Kim, Jeong-ryeol
    • The Journal of the Korea Contents Association
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    • v.17 no.6
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    • pp.408-414
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    • 2017
  • This paper aims to investigate the value and resilience of Nogeoldae which was written at the end of Koryo dynasty and has been used as the most important foreign language education materials throughout the 500 years of Chosun dynasty. To this end, 106 volumes of dialogues, 12 of meeting, 17 of lodging, 21 of Daedo bound, 34 of Daedo lives and 11 of return in Nogeoldae are analyzed by an average length of the sentences, an average length of words, type-token ratio, number of words before main verbs and number of words before nouns to identify the progressive degree of the complexity. The result of the analysis shows that Nogeoldae presents a desired progressive complexity found in modern foreign language textbooks.

Differential gene expression profiles of periodontal soft tissue from rat teeth after immediate and delayed replantation: a pilot study

  • Chae, Yong Kwon;Shin, Seo Young;Kang, Sang Wook;Choi, Sung Chul;Nam, Ok Hyung
    • Journal of Periodontal and Implant Science
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    • v.52 no.2
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    • pp.127-140
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    • 2022
  • Purpose: In dental avulsion, delayed replantation usually has an uncertain prognosis. After tooth replantation, complex inflammatory responses promote a return to periodontal tissue homeostasis. Various types of cytokines are produced in the inflammatory microenvironment, and these cytokines determine the periodontal tissue response. This study aimed to identify the gene expression profiles of replanted teeth and evaluate the functional differences between immediate and delayed replantation. Methods: Maxillary molars from Sprague-Dawley rats were extracted, exposed to a dry environment, and then replanted. The animals were divided into 2 groups according to the extra-oral time: immediate replantation (dry for 5 minutes) and delayed replantation (dry for 60 minutes). Either 3 or 7 days after replantation, the animals were sacrificed. Periodontal soft tissues were harvested for mRNA sequencing. Hallmark gene set enrichment analysis was performed to predict the function of gene-gene interactions. The normalized enrichment score (NES) was calculated to determine functional differences. Results: The hallmark gene sets enriched in delayed replantation at 3 days were oxidative phosphorylation (NES=2.82, Q<0.001) and tumor necrosis factor-alpha (TNF-α) signaling via the nuclear factor kappa light chain enhancer of activated B cells (NF-κB) pathway (NES=1.52, Q=0.034). At 7 days after delayed replantation, TNF-α signaling via the NF-κB pathway (NES=-1.82, Q=0.002), angiogenesis (NES=-1.66, Q=0.01), and the transforming growth factor-beta signaling pathway (NES=-1.46, Q=0.051) were negatively highlighted. Conclusions: Differentially expressed gene profiles were significantly different between immediate and delayed replantation. TNF-α signaling via the NF-κB pathway was marked during the healing process. However, the enrichment score of this pathway changed in a time-dependent manner between immediate and delayed replantation.

Intraoperative Nerve Monitoring during Minimally Invasive Esophagectomy and 3-Field Lymphadenectomy: Safety, Efficacy, and Feasibility

  • Srinivas Kodaganur Gopinath;Sabita Jiwnani;Parthiban Valiyuthan;Swapnil Parab;Devayani Niyogi;Virendrakumar Tiwari;C. S. Pramesh
    • Journal of Chest Surgery
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    • v.56 no.5
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    • pp.336-345
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    • 2023
  • Background: The objective of this study was to demonstrate the safety, efficacy, and feasibility of intraoperative monitoring of the recurrent laryngeal nerves during thoracoscopic and robotic 3-field esophagectomy. Methods: This retrospective analysis details our initial experience using intraoperative nerve monitoring (IONM) during minimally invasive 3-field esophagectomy. Data were obtained from a prospectively maintained database and electronic medical records. The study included all patients who underwent minimally invasive (video-assisted thoracic surgery/robotic) transthoracic esophagectomy with neck anastomosis. The patients were divided into those who underwent IONM during the study period and a historical cohort who underwent 3-field esophagectomy without IONM at the same institution. Appropriate statistical tests were used to compare the 2 groups. Results: Twenty-four patients underwent nerve monitoring during minimally invasive 3-field esophagectomy. Of these, 15 patients underwent thoraco-laparoscopic operation, while 9 received a robot-assisted procedure. In the immediate postoperative period, 8 of 24 patients (33.3%) experienced vocal cord paralysis. Relative to a historical cohort from the same institution, who were treated with surgery without nerve monitoring in the preceding 5 years, a 26% reduction was observed in the nerve paralysis rate (p=0.08). On follow-up, 6 of the 8 patients with vocal cord paralysis reported a return to normal vocal function. Additionally, patients who underwent IONM exhibited a higher nodal yield and a decreased frequency of tracheostomy and bronchoscopy. Conclusion: The use of IONM during minimally invasive 3-field esophagectomy is safe and feasible. This technique has the potential to decrease the incidence of recurrent nerve palsy and increase nodal yield.

Stock Market Forecasting : Comparison between Artificial Neural Networks and Arch Models

  • Merh, Nitin
    • Journal of Information Technology Applications and Management
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    • v.19 no.1
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    • pp.1-12
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    • 2012
  • Data mining is the process of searching and analyzing large quantities of data for finding out meaningful patterns and rules. Artificial Neural Network (ANN) is one of the tools of data mining which is becoming very popular in forecasting the future values. Some of the areas where it is used are banking, medicine, retailing and fraud detection. In finance, artificial neural network is used in various disciplines including stock market forecasting. In the stock market time series, due to high volatility, it is very important to choose a model which reads volatility and forecasts the future values considering volatility as one of the major attributes for forecasting. In this paper, an attempt is made to develop two models - one using feed forward back propagation Artificial Neural Network and the other using Autoregressive Conditional Heteroskedasticity (ARCH) technique for forecasting stock market returns. Various parameters which are considered for the design of optimal ANN model development are input and output data normalization, transfer function and neuron/s at input, hidden and output layers, number of hidden layers, values with respect to momentum, learning rate and error tolerance. Simulations have been done using prices of daily close of Sensex. Stock market returns are chosen as input data and output is the forecasted return. Simulations of the Model have been done using MATLAB$^{(R)}$ 6.1.0.450 and EViews 4.1. Convergence and performance of models have been evaluated on the basis of the simulation results. Performance evaluation is done on the basis of the errors calculated between the actual and predicted values.

Efficient Verifiable Top-k Queries in Two-tiered Wireless Sensor Networks

  • Dai, Hua;Yang, Geng;Huang, Haiping;Xiao, Fu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.6
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    • pp.2111-2131
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    • 2015
  • Tiered wireless sensor network is a network model of flexibility and robustness, which consists of the traditional resource-limited sensor nodes and the resource-abundant storage nodes. In such architecture, collected data from the sensor nodes are periodically submitted to the nearby storage nodes for archive purpose. When a query is requested, storage nodes also process the query and return qualified data as the result to the base station. The role of the storage nodes leads to an attack prone situation and leaves them more vulnerable in a hostile environment. If any of them is compromised, fake data may be injected into and/or qualified data may be discarded. And the base station would receive incorrect answers incurring malfunction to applications. In this paper, an efficient verifiable top-k query processing scheme called EVTQ is proposed, which is capable of verifying the authentication and completeness of the results. Collected data items with the embedded information of ordering and adjacent relationship through a hashed message authentication coding function, which serves as a validation code, are submitted from the sensor nodes to the storage nodes. Any injected or incomplete data in the returned result from a corresponded storage node is detected by the validation code at the base station. For saving communication cost, two optimized solutions that fuse and compress validation codes are presented. Experiments on communication cost show the proposed method is more efficiency than previous works.

A Study on the Development of the Medical Gowns for Interns and Residents at a University Hospital -Focus on Pockets and Movement Adaptability- (대학종합병원 전공의 가운 개발에 관한 연구 -수납 및 활동성을 중심으로-)

  • Yun, Hee-Young;Choi, Hei-Sun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.34 no.5
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    • pp.819-830
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    • 2010
  • This study proposes medical gowns for interns and residents that address the functions of utility and activity. Based on the questionnaires, the prototype focused on the pockets for practical use and movement adaptability. Functional pockets were made by increasing pocket sizes and separating pockets with sections according to use. An inside pocket and a loop for an identification tag was placed on the chest pocket and the side seam pocket were oblique lined. To resolve horizontal stress on the back of the gown,6 cm action pleats were added at both ends of the bladebone. The elbow area was tucked up to improve the workplace activities. To reduce hamper on the gown hemline, slits were added along the gown side seam. The front button was changed into an inside button closure. The cuffs, belt, and back waist belt were removed due to occupational cases of inconvenience. The length of the sleeves was adjusted with belts to improve the movement of the arms. In accordance with design preference, the gown was designed to be knee-length with wrist length sleeves. Blue colored (2.5PB 3/12: by Munsell) material was inserted to reduce the contamination on the neck, cuffs, front closure, and hemline area. The planning cloth of the experimental gown was designed to improve activity function, cleaning, and comfort from light materials. The field test (with 30 doctors at university hospitals and the objective assessment with 9 subject groups)were done by the valuation between the existing gown and the prototype. The results showed that the prototype had to be modified by decreasing the pocket size, expanding the usage of the penholder, and simplify front pockets in order to maintain unity. The loop for the identification tag, inside pocket, and the blue colored material had to be removed. The front closure of the gown had to return to its original state.