• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5169-5173
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• 2015

To determine the efficacy of postoperative adjuvant chemotherapy with paclitaxel plus cisplatin (Taxol + DDP, TP therapy) for stage IIA esophageal squamous cell carcinoma (ESCC) and to investigate the expression of RUNX3 in lymph node metastasis-negative esophageal cancer and its relationship with medical prognosis, a retrospective summary of clinical treatment of 143 cases of stage IIA esophageal squamous cell carcinoma patients was made. The patients were divided into two groups, a surgery alone control group (52 patients) and a chemotherapy group that received postoperative TP therapy (91 patients). The disease-free and 5 year survival rates were compared between the groups and a multivariate analysis of prognostic factors was performed. The same analysis was performed for cases classified as RUNX3 positive and negative, with post-operative specimens assessed by immunohistochemistry. Although the disease-free and 5 year survival rates in control and chemotherapy groups did not significantly differ and there was no significance in RUNX3 negative cases, postoperative adjuvant chemotherapy in the chemotherapy group was shown to improve disease-free and 5 year survival rate compared to the control group in RUNX3 positive cases. On Cox regression multivariate analysis, postoperative adjuvant chemotherapy (P<0.01) was an independent prognostic factor for RUNX3 positive cases, suggesting that postoperative TP may be effective as adjuvant chemotherapy for stage IIA esophageal cancer patients with RUNX3 positive lesions.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.4
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• pp.196-207
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• 2015

Purpose : To observe effects of Korean Medicine treatment for genital warts.Methods : In a single private clinic from February 2014 to February 2015, we did retrospective chart review for 326 patients with genital warts who had been treated by Korean Medicine. Korean Medicine treatment included herbal treatment and herbal ointment.Results : A total of 326 patients were enrolled in this study: 62.7%(n=219) male, 32.8%(n=107) female. In the type of diagnosis, new diagnosis was 45.4%(n=148) and recurrent disease was 54.6%(n=178). Complete clearance was achieved 63.2%(n=206) and treatment period was 3.5 months(range:1-9). Partial clearance-good was 15%(n=49), partial clearance-poor was 4.9%(n=16), non response was 16.9%(n=55) and the average treatment period was 4.3 months(range:1-14). In complete clearance group, female and the prevalence of less than 1 year were statistically significant(p<0.05). There was no recurrence of genital warts after TKM treatment during follow-up period(4-13months).Conclusion : This study suggest that Korean Medicine may be an effective treatment for genital warts.

• Korean Journal of Health Education and Promotion
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• v.31 no.2
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• pp.55-64
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• 2014

Objectives: This study is to identify the effects of utilizing a telemedicine service system on patients with hypertension at home in rural areas. Methods: The study was designed to be a retrospective case-control study. The subjects of this study were 152patients with hypertension who were managed by community health practitioner posts; using telemedicine service system group (n=76), usual care group (n=76). The data was collected through EMR (electric medical record) from September to December, 2013, and analyzed by descriptive statistics of $x^2$/t-test and ANCOVA. Results: The analysis showed that telemedicine service system was an effective way to deal with body weight (F=4.723, p=.031) and BMI (F=5.225, p=.024). Conclusions: This study provides evidence for utilizing the telemedicine service system based on information technology as intervention method in the hypertension management.

• Journal of Veterinary Clinics
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• v.25 no.6
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• pp.476-481
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• 2008

A retrospective study of 17 dogs with hyperadrenocorticism (HAC) was performed to evaluate the clinical and clinicopathological outcomes in dogs with pituitary-dependent HAC or adrenal gland-dependent HAC. Sixteen dogs were monitored at day 10, 30 and 90 then every 3 month after first presentation. In each examination, physical examination and ACTH stimulation test and client questionnaire were performed. In 17 cases, eight dogs were successfully treated with mitotane therapy (median dose 16.7 mg/kg; range 5.3 to 50 mg/kg, SID); another one dog showed favorable response, but the clients declined to further treatment before the full control of the disease had been achieved; four dogs showed poor response to treatment. One dog was euthanized due to septicemia. These results showed canine HAC can be medically managed successfully without side effects at the doses used in this study.

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.4
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• pp.233-238
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• 2019

The aim of this study was to investigate the effect of Korean medicine treatments on pain reduction and functional improvement of patients after rotator cuff surgery. We studied 10 patients who had admitted to Dunsan Korean Medical hospital after have being diagnosed as rotator cuff tear and got a surgery at other hospital from April 30, 2014 to April 30, 2019. This study was conducted as retrospective study which analyzes patient's medical records. Statistical analysis was performed using the IBM SPSS statistics 24 program. We used Numeric Rating Scale to evaluate pain reduction, Range of Motion to evaluate shoulder functional improvement and Five-point likert scale to evaluate the patient's satisfaction. The result showed that Korean medicine treatments statistically significantly reduced pain on the patients after rotator cuff surgery. Although there were improvement of Range of Motion, it wasn't statistically significant. In conclusion, we found that the Korean medicine treatments showed a positive effect on pain reduction of patients after rotator cuff surgery and got a high satisfaction.

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.4
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• pp.219-225
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• 2019

The objective of this study is to observe the effectiveness of complex Korean Medicine treatments on pain reduction of patients after meniscal surgery. We analyzed 16 patients who have been diagnosed as Meniscal injury on Magnetic Resonance Imaging(MRI) scan and had admitted to Dunsan Korean Medical hospital from January 30, 2014 to April 30, 2019. The analysis was conducted as retrospective study which analyzes patient's medical records. Statistical analysis was performed using the IBM SPSS statistics 25 program. We used Numeric Rating Scale to evaluate pain reduction, Five-point likert scale to asses treatment satisfaction. The result showed that there were statistically significant pain reduction on the postoperative meniscal injury patients treated with complex Korean Medicine treatments. In conclusion, we found that the complex Korean Medicine treatments showed a positive effect on pain reduction of postoperative meniscal injury patients. Further research is required to confirm the effectiveness of Korean Medicine treatment.

• Clinics in Shoulder and Elbow
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• v.24 no.1
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• pp.36-41
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• 2021

Chronic shoulder pain not relieved by either conservative or surgical management is referred to as chronic refractory shoulder pain. This is a retrospective case series where chronic refractory shoulder pain patients were treated either with peripheral nerve stimulation (PNS) or with pulsed radiofrequency (p-RF) therapy to the suprascapular nerve. Both patients receiving PNS reported 100% pain relief for the first month. At the 3- and 6-month follow-ups, one patient continued to experience 100% relief while the other reported 90% relief. One patient undergoing p-RF experienced about 90% pain relief at both 1- and 3-month intervals and 0% relief at the 6-month interval. The other patient with p-RF experienced 33% relief at 1-month and 0% relief thereafter. No patient reported any complications. The results of previous randomized controlled trials evaluating the efficacy of p-RF administered to the suprascapular nerve were mixed, and there is a lack of published studies on PNS effects. Neuromodulation of the suprascapular nerve can be effective for chronic refractory shoulder pain patients. Larger scale randomized controlled trials comparing PNS and p-RF are needed to better understand their respective therapeutic capacity.

• The Journal of Internal Korean Medicine
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• v.31 no.3
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• pp.437-447
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• 2010

Obejectives : To investigate the clinical effect of electroacupuncture and bee venom acupuncture for benign prostatic hyperplasia(BPH) symptoms. Methods : Among 39 outpatients who were treated at a BPH clinic, 8 were finally selected for analysis by charts-review, retrospectively. They were treated by electroacupuncture and bee venom acupuncture more than 3 times. We estimated the effectiveness of the treatments by using the International Prostate Symptom Score (IPSS) questionnaire and checking their nocturia frequency. On the basis of these variables, we analyzed the statistical significations of symptom improvements. Results : Among 8 patients, the IPSS and nocturia frequency showed significant improvement after the final treatment compared with baseline (P = .0078, P = .0078). The IPSS significantly decreased even after the 1st treatment and also after the 2nd treatment compared with the baseline (P = .0078, P = .0078). The IPSS at post final-treatment, post 1st- and post 2nd treatment also showed significant improvement compared with IPSS at baseline in 6 severe symptomatic patients(P = .031, P = .031, P = .031). Nocturia frequency decreased after the 1st treatment compared with baseline and showed significant improvement between baseline and post 2nd treatment (P = .0078). Conclusions : In a retrospective and cross-sectional study investigating the clinical effects of electroacupuncture and bee venom acupuncture on BPH, these treatments proved to have significant therapeutic effects, particularly for various symptoms involving frequent nocturia.

• The Journal of Internal Korean Medicine
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• v.38 no.6
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• pp.930-943
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• 2017

Objectives: The purpose of this study was to investigate the clinical effects of HongYi pharmacopuncture monotherapy on female voiding dysfunction. Methods: Korean medical practitioners who used HongYi pharmacopuncture to treat female patients complaining of dysuria were surveyed. They performed a retrospective chart review of 31 female patients who visited their Korean medical clinic for dysuria. General characteristics, marital status, urologic medical history, International Prostate Symptom Score (IPSS), International Consultation on Incontinence Modular Questionnaire-Female Lower Urinary Tract Symptoms (ICIQ-FLUTS), and related adverse events were examined. Results: Of 31 cases received, 29 were selected for analysis. Two cases were excluded because treatment was not continued through four weeks. In all cases, IPSS and ICIQ-FLUTS scores were significantly decreased after treatment. Adverse reactions occurred during treatment in four cases. Conclusions: These results suggest that treatment by HongYi pharmacopuncture is effective in improving lower urinary tract symptoms in women. Further studies will be needed for evaluation of clinical responses, to evaluate the safety and efficacy of HongYi pharmacopuncture treatment for female patients complaining of dysuria.

• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.1
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• pp.66-72
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• 2016

This retrospective observational study was aimed to assess that Shinchubogun-tang (Shenzhuibujian-tang ; SBT) improves the symptoms related to lumbar disc herniation. We analyzed the medical records of 36 patients, who were satisfied with inclusion and exclusion criteria. The patients were diagnosed with lumbar disc herniation and prescribed with SBT in addition to Korean medical common treatments at Dunsan Korean Medicine Hospital of Daejeon University from January 1st, 2013 to November 30th, 2015. The effects of SBT was evaluated by comparing before and after taking SBT through 0-10 visual analogue scale(VAS) of the symptoms including lower back pain, radiating pain, and lower extremity numbness. The average period of common Korean medicine treatment before SBT prescription was 9.78 days and then the patients received SBT along with common Korean medicine treatment for 13.17 days on average. SBT plus common korean medicine treatment group significantly decreased VAS score of lower back pain from 5.40±1.62 to 3.28±1.70 (p<0.01), radiating pain from 5.60±1.42 to 2.35±1.79 (p<0.01), lower extremity numbness from 5.77±1.52 to 2.55±1.85(p<0.01). These results demonstrated that SBT might have a potential on improvement of lumbar disc herniation by reducing the symptoms of lower back pain, radiating pain, and lower extremity numbness.