• Title/Summary/Keyword: Retina structure

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Simulator Development and Analysis for Signal Flow Pathway in Vertebrate Retina (척추동물 망막의 신호 전달 경로 시뮬레이터 개발 및 분석)

  • Baek, Seungbum;Jang, Young-Jo;Cho, Kyoungrok
    • The Journal of the Korea Contents Association
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    • v.18 no.11
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    • pp.655-664
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    • 2018
  • Retina transforms the external light into electrical signal that stimulates visual cortex of the brain. Electrical modeling of the retina is useful to understand its structure and action that is a prerequisite to implement the retina as a hardware device. This paper introduces a 2-D electrical network model of vertebrate's retina considering signal pathway of retinal cells and synapses. We implemented a simulator of the retina based on the electrical network model to analyze its operation under various circumstances. Compared to the prior studies, It might contribute designing of artificial retina device in terms of that this study specifically observed input and output reactions of each cell and synapse node under various light intensity on the retina.

The Structure of Visual Cells in the Retina of the Pond Loach, Misgurnus anguillicaudatus (Pisces; Cobitidae)

  • Kim, Chi-Hong;Kim, Jae-Goo;Park, Jong-Young
    • Applied Microscopy
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    • v.45 no.4
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    • pp.254-258
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    • 2015
  • A histological study on the retina of Misgurnus anguillicaudatus was carried out by light microscopy and scanning electron microscopy as part of getting information about relation between its habitat and visual cells. The visual cells of the retina in M. anguillicaudatus, a bottom-dwelling freshwater pond loach in stagnant or slow waters such as swamps, reservoirs and paddy fields, consists of double cones and large rods. The cones form a row mosaic pattern in which the partners of double cones are linearly oriented with a large rod. In a double cone, the two members are unequal such that one cone may be longer than the other.

Three Dimensional Reconstruction of Cellular Structure in Drosophila Retina Using High Voltage Electron Microscopy (초고압전자현미경을 이용한 초파리 망막 세포의 3차원 구조)

  • Mun, Ji-Young;Lee, Kyung-Eun;Han, Sung-Sik
    • Applied Microscopy
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    • v.39 no.2
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    • pp.185-189
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    • 2009
  • Studies about the structure of Drosophila melanogaster retinal cell using electron microscopy have been carried out in details since 1960s. However, these results can have limitations in functional research because of two-dimensional structure. In this study, the adult retina of Drosophila melanogaster was investigated by employing high pressure freezing method, serial sections, high voltage electron microscopy, and 3-dimensional reconstruction method. From there results, mitochondria, microtubules, and nuclei were reconstructed as 3-dimensional structure using IMOD program. The 3D structure of these organelles showed that mitochondira mainly located in distal region near lens, and microtubule mainly located in distal and basal region. The 3D reconstruction of these organelles can be used for a critical evaluation in the dynamic change of cellular organelles caused by functional abnormality like retinal degeneration.

A novel reitna chip with simple wiring for edge extraction (가장자리 검출을 위한 상호연결을 가진 망막칩)

  • ;;;Masahiro Ohtani;Hiroo Yonezy
    • Proceedings of the IEEK Conference
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    • 2000.11c
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    • pp.153-156
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    • 2000
  • A novel silicon retina chip based on the information processing in the vertebrate retina was designed. The chip has a novel wiring structure in which all pixels are connected through the channel of MOS transistors, which simplifies a wiring structure compared with conventional resistive networks. The proposed structure minimizes the pixel area and certainly increases a fill factor since each pixel consists of only two photodiodes and three MOS transistors. It also enables the chip to operate over a wide range of light intensity by adjusting its conductance with the gate voltage. Simulation results with SPICE showed that the chip could extract the edge of input images successfully.

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High-Speed SD-OCT for Ultra Wide-field Human Retinal Three Dimensions Imaging using GPU (병렬처리 그래픽 기술 기반의 Spectral Domain-Optical Coherence Tomography를 이용한 3차원 광 대역 망막 촬영)

  • Park, Kibeom;Cho, Nam Hyun;Wijesinghe, Ruchire Eranga Henry;Kim, Jeehyun
    • Journal of Biomedical Engineering Research
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    • v.34 no.3
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    • pp.135-140
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    • 2013
  • We have developed an ultra wide-field of view Optical Coherence Tomography(OCT) which has capability to 2D and 3D views of cross-sectional structure of in vivo human retina. Conventional OCT has a limitation in visualizing the entire retina due to a reduced field of view. We designed an optical setup to significantly improve the lateral scanning range to be more than 20 mm. The entire human retinal structure in 2D and 3D was reported in this paper with the developed OCT system. Also, we empirically searched an optimized image size for real time visualization by analyzing variation of the frame rate with different lateral scan points. The size was concluded to be $1024{\times}2000{\times}300$ pixels which took 9 seconds for visualization.

Study on the Fine Structure of Retina of Anterior Lateral Eyes in Pardosa astrigera L. Koch (Aranea: Lycosidae) (별늑대거미 (Pardosa astrigera L. Koch) 전측안(前側眼) 망막(綱膜)의 미세구조(微細構造)에 관한 연구)

  • Jeong, Moon-Jin;Moon, Myung-Jin
    • Applied Microscopy
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    • v.24 no.3
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    • pp.1-9
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    • 1994
  • Pardosa astrigera possessed eight eyes arranged in three rows on the frontal carapace. A pair of small anterior lateral eyes (ALE) flanked each side by an anterior median eyes (AME) lay along the anterior margin that was situated on the anterior row of clypeus. The anterior lateral eye was composed of cornea, vitreous body, and retina. Cornea was made up mainly of exocuticle lining the cuticle. Lens in anterior lateral eye was biconvex type which bulged into the cavity of the eyecup. Outer and inner central region of lens were approximately spherical with radius of curvature $5.6{\mu}m$ and $12.5{\mu}m$, respectly. Vitreous body formed a layer between the cuticular lens and retina. They formed biconcave shape. Retina of the anterior lateral eyes was composed of three types of cells: visual cells, glia cells, and pigment cells. The visual cells were unipolar neuron, as were the receptor of the posterior lateral eye. But cell body was unique to the anterior lateral eyes. They were giant cell, relatively a few in number, and under the layer of vitreous bodies. Each visual cell healed rhabdomeres for a short stretch beneath the cell body. Rhabdomes were irregulary pattern in retina and electron dense pigment granules scattered between the rhabdomes. Glia cell situated at the cell body of visual cell and glia cell process reached to rhabdomere portion. Below the rhabdome, tapetum were about $30{\mu}m$ distance from lens, which composed of 4-5 layers. It was about $25{\mu}m$ length that intermediate segment of distal portion of visual cell. Electron dense pigment granules between the intermediate segment were observed.

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The Effect of Laser Irridation on the Ultrastructure of Retina (Laser 조사가 망막의 미세구조에 미치는 영향)

  • Kim, Douk Hoon;Mun, Jung Hak
    • Journal of Korean Ophthalmic Optics Society
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    • v.1 no.1
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    • pp.15-22
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    • 1996
  • The fine structure of retinal tissue was studied to investigate on effect of Laser irridation on the ICR mouse with electron microscope. The results obtained were as follows: 1. At the normal groups, the most retinal layers were a complex structure, consisting of several specific cells and nerve fiver. 2. In the increasing time of Laser irridation, each cell layer of retina was not uniform of the structure and band. The visual cells were severely heterochromatin swelling of cytoplasm, irregular shape & heterochromatin of nuclear, and disappear of some cytoplasm. The nucleus and nerve fiber of retinal layer was a very irregular shape, formation of vesicle, not identify of each intercellular boundary. The pigment epithelial cells were not an uniform, a large vesicle formation of cytoplasm, and a condensation & very irregular shape of nucleus.

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Information Processing in Primate Retinal Ganglion

  • Je, Sung-Kwan;Cho, Jae-Hyun;Kim, Gwang-Baek
    • Journal of information and communication convergence engineering
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    • v.2 no.2
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    • pp.132-137
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    • 2004
  • Most of the current computer vision theories are based on hypotheses that are difficult to apply to the real world, and they simply imitate a coarse form of the human visual system. As a result, they have not been showing satisfying results. In the human visual system, there is a mechanism that processes information due to memory degradation with time and limited storage space. Starting from research on the human visual system, this study analyzes a mechanism that processes input information when information is transferred from the retina to ganglion cells. In this study, a model for the characteristics of ganglion cells in the retina is proposed after considering the structure of the retina and the efficiency of storage space. The MNIST database of handwritten letters is used as data for this research, and ART2 and SOM as recognizers. The results of this study show that the proposed recognition model is not much different from the general recognition model in terms of recognition rate, but the efficiency of storage space can be improved by constructing a mechanism that processes input information.

Design and Fabrication of $8{\times}8$ Foveated CMOS Retina Chip for Edge Detection (물체의 윤곽검출을 위한 $8{\times}8$ 방사형 CMOS 시각칩의 설계 및 제조)

  • Kim, Hyun-Soo;Park, Dae-Sik;Ryu, Byung-Woo;Lee, Soo-Kyung;Lee, Min-Ho;Shin, Jang-Kyoo
    • Journal of Sensor Science and Technology
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    • v.10 no.2
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    • pp.91-100
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    • 2001
  • A $8{\times}8$ foveated (log-polar) retina chip for edge detection has been designed and fabricated using CMOS technology. Retina chip performs photo-input sensing, edge extraction and motion detection and we focused edge extraction. The pixel distribution follows the log-polar transform having more resolution in the center than in the periphery and can reduce image information selectively. This kind of structure has been already employed in simple image sensors for normal cameras, but never in edge detection retina chip. A scaling mechanism is needed due to the different pixel size from circumference to circumference. A mechanism for current scaling in this research is channel width scaling of MOS transistor. The designed chip has been fabricated using standard $1.5{\mu}m$ single-poly double-metal CMOS technology.

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Retina-Motivated CMOS Vision Chip Based on Column Parallel Architecture and Switch-Selective Resistive Network

  • Kong, Jae-Sung;Hyun, Hyo-Young;Seo, Sang-Ho;Shin, Jang-Kyoo
    • ETRI Journal
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    • v.30 no.6
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    • pp.783-789
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    • 2008
  • A bio-inspired vision chip for edge detection was fabricated using 0.35 ${\mu}m$ double-poly four-metal complementary metal-oxide-semiconductor technology. It mimics the edge detection mechanism of a biological retina. This type of vision chip offer several advantages including compact size, high speed, and dense system integration. Low resolution and relatively high power consumption are common limitations of these chips because of their complex circuit structure. We have tried to overcome these problems by rearranging and simplifying their circuits. A vision chip of $160{\times}120$ pixels has been fabricated in $5{\times}5\;mm^2$ silicon die. It shows less than 10 mW of power consumption.

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