• Journal of Ginseng Research
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• v.44 no.2
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• pp.341-349
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• 2020

Background: The replicative senescence of human dermal fibroblasts (HDFs) is accompanied by growth arrest. In our previous study, the treatment of senescent HDFs with Rg3(S) lowered the intrinsic reactive oxygen species (ROS) levels and reversed cellular senescence by inducing peroxiredoxin-3, an antioxidant enzyme. However, the signaling pathways involved in Rg3(S)-induced senescence reversal in HDFs and the relatedness of the stereoisomer Rg3(R) in corresponding signaling pathways are not known yet. Methods: We performed senescence-associated β-galactosidase and cell cycle assays in Rg3(S)-treated senescent HDFs. The levels of ROS, adenosine triphosphate (ATP), and cyclic adenosine monophosphate (cAMP) as well as the mitochondrial DNA copy number, nicotinamide adenine dinucleotide (NAD)⁺/1,4-dihydronicotinamide adenine dinucleotide (NADH) ratio, and NAD-dependent sirtuins expression were measured and compared among young, old, and Rg3(S)-pretreated old HDFs. Major signaling pathways of phosphatidylinositol 3-kinase/Akt, 5' adenosine monophosphate-activated protein kinase (AMPK), and sirtuin 1/3, including cell cycle regulatory proteins, were examined by immunoblot analysis. Results: Ginsenoside Rg3(S) reversed the replicative senescence of HDFs by restoring the ATP level and NAD⁺/NADH ratio in downregulated senescent HDFs. Rg3(S) recovered directly the cellular levels of ROS and the NAD⁺/NADH ratio in young HDFs inactivated by rotenone. Rg3(S) mainly downregulated phosphatidylinositol 3-kinase/Akt through the inhibition of mTOR by cell cycle regulators like p53/p21 in senescent HDFs, whereas Rg3(R) did not alter the corresponding signaling pathways. Rg3(S)-activated sirtuin 3/PGC1α to stimulate mitochondrial biogenesis. Conclusion: Cellular molecular analysis suggests that Rg3(S) specifically reverses the replicative senescence of HDFs by modulating Akt-mTOR-sirtuin signaling to promote the biogenesis of mitochondria.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.32 no.2
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• pp.109-115
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• 2014

The aim of the study is to present a method to build an octree and to query from it for huge 3D point clouds of which volumes correspond or surpass the main memory, based on the memory-efficient octree developed by Han(2013). To the end, the method directly refers to 3D point cloud stored in a file on a hard disk drive instead of referring to that duplicated in the main memory. In addition, the method can save time to rebuild octree by storing and restoring it from a file. The memory-referring method and the present file-referring one are analyzed using a dataset composed of 18 million points surveyed in a tunnel. In results, the memory-referring method enormously exceeded the speed of the file-referring one when generating octree and querying points. Meanwhile, it is remarkable that a still bigger dataset composed of over 300 million points could be queried by the file-referring method, which would not be possible by the memory-referring one, though an optimal octree destination level could not be reached. Furthermore, the octree rebuilding method proved itself to be very efficient by diminishing the restoration time to about 3% of the generation time.

• Journal of the Economic Geographical Society of Korea
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• v.13 no.1
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• pp.111-125
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• 2010

For a shift to a new paradigm that allows restoring solidarity among class, gender, and race, it is necessary to closely investigate the differences between Marxist view and poststructuralist view which provide theoretical basis for labor movement and for feminist movement, respectively. However, little effort has been devoted to this task. This paper critically compares two best wellknown geographers; Harvey's class-centered theory and Gibson-Graham's post-structuralist feminist approach by focusing on their understandings of "difference". David Harvey argues that racial/gender discrimination is another form of class-exploitation and puts priority on the solidarity based on the commonality of labor. On the contrary Gibson-Graham argues that the privileging of class above all else marginalizes other political dimension, and proposes the deconstruction of hegemonic discourse of capitalism and the construction of "community economies", Based on the critical survey of both theories, I propose that understanding the role that spatiality plays in capital accumulation process is the key to compromise two different approaches.

• Journal of Environmental Policy
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• v.6 no.2
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• pp.47-70
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• 2007

In recent days, people's requests about water resources have been developed from managing quality and quantity of water resources to forming a river environment by restoring normal function of river. To meet these requests, it is necessary to establish the concept of environmental flows. In Korea, the environmental flows was introduced as a concept of river maintenance flows in a sense of river management. The function of river maintenance flows has been changed according to what the major issue is in that age such as navigation, water quality, and prevention of saline water intrusion. As the assesment of river maintenance flows in Korea focused mainly on the function of water usage oriented in human, it could not be defined and emphasized in a sense of ecosystem as a pure meaning of environmental flows. And while the existing river maintenance flows are included the assesment of flows, there is not a practical procedure to supply them and the efficient management in a sense of environment is not performed. The environmental flows should be further developed from the river maintenance flows and changed to a new concept focused on maintaining the health of ecosystem. In other words, the environmental flows should be defined as a necessary flows for maintaining the function of river and its original value, and be considered on the same or higher value of flows for maintenance of economic activity, recreation, and power generation.

• The KIPS Transactions:PartA
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• v.12A no.6 s.96
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• pp.515-522
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• 2005

This paper presents a method for effectively modeling inlay/onlay prostheses restoring a tooth that are partially destroyed. An inlay/onlay is composed of internal surface adhering to an abutment, and external surface revealed to the outside sight. Internal surfaces are modeled using Minkowski sum expanding the grinded surface parts of abutments so that the internal surfaces can adhere to the abutments with closer contact. In modeling external surfaces, we exploit 3D mesh deformation techniques: DMFFD(direct manipulation free-form deformation)[19] and MWD(multiple wires deformation)[17] with three kinds of informations: standard teeth models, mesh data obtained by scanning a plaster cast of a patient's tooth, FGP(functionally guided plane) measuring the occlusion of the patients's teeth. The standard teeth models are used for building up the basic shapes of external surfaces, while the plaster fast and FGP data are used for reflecting the unique properties of adjacent md occlusal surfaces of the patients's teeth, which are slightly different to each other but very important for correct functioning. With these informations as input data, the adjacent and occlusal surfaces are automatically generated as mesh data using the techniques of DMFFD and m, respectively. Our method was implemented so that inlay/onlay prostheses fan be designed more accurately by visualizing the generated mesh models with requirements by dentists.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.17 no.1
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• pp.45-64
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• 2014

This study was carried out to offer the ecological data for restoring and maintaining a local stream by analyzing the vegetation and flora in Geumsan Stream and Gisa Stream, Geumsan-gun, Chungcheongnam-do, Korea. As a result of comparison of realities of land use near Geumsan Stream and Gisa Stream, in Geumsan Stream, the ratio of residential areas, commercial and business places, and places of transportation facilities was high. With these types of land use aggregating densely in the center, farmlands were formed on both sides. On the other hand, in Gisa Stream, farmlands were distributed evenly in all sections. As a result of comparison of flora of the two streams, Geumsan Stream had a total of 166 taxons including 53 families, 131 genuses, 139 species, 23 varieties, and 4 forms, and Gisa Stream had a total of 142 taxons including 42 families, 111 genuses, 116 species, 21 varieties, and 5 forms. As a result of calculation of the Naturalization Index and Urbanization Index, the indices were analyzed to be 23.5% and 12.1% in Geumsan Stream and to be 21.8% and 9.7% in Gisa Stream, respectively. Hence, Geumsan Stream showed higher figures in both evaluation indices than those of Gisa Stream. In addition, as a result of calculation of the Actual Urbanization Index, which is the index supplemented by considering the species pool and area, it could be known that Geumsan Stream (0.0285) was urbanized more than Gisa Stream (0.0107) by about 2.7 times. A total of 18 plant communities were classified in Geumsan Stream and Gisa Stream. In Geumsan Stream, 14 vegetation types were identified, and it was analyzed that there are various vegetation types including Phalaris arundinacea community, Zoysia japonica community, Phragmites japonica-Phalaris arundinacea community, etc. evenly distributed. 11 vegetation types were identified in Gisa Stream, and it was examined that Phragmites japonica community is widely distributed in all sections.

• Journal of the Society of Disaster Information
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• v.13 no.3
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• pp.398-404
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• 2017

In this study, the field investigation was carried out in an area damaged by flood, which recently occurred in Chungcheong region, in order to establish a disaster safety village in a rural area. In addition, the history and characteristics of a village in Garisan-ri, Inje-gun, Gangwon-do that experienced loss of life and property caused by flood in 2006 were analyzed through monitoring. The village was restored and has been operated as a disaster prevention experience village for the purpose of disaster prevention, and its structural and non-structural status was monitored during the analysis. Based on the results, application measures for establishing a disaster safety village in a rural area in future were examined. At the time of restoring food damage, the residents' participation was actively reflected in the process of establishing the disaster prevention experience village in Garisan-ri. The village has been currently operated until now as an example of disaster safety village in rural regions, and various activities including training and educational programs are carried out in order to reinforce the disaster prevention capability of residents. The findings of this study can be used for establishing a disaster safety village in a rural area based on such characteristics.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.5
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• pp.608-614
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• 2018

In addition to the diffusion of ICT technology, various protocols of short range wireless communication technology are being applied for efficient information operation. However, due to limitations of short-range wireless communication, communication is not smooth in places where frequency environment is poor, such as frequency confusion and warehouse type factory. When an alternative is needed. The development of LED technology and expansion of infrastructure through LED based visible light communication is attracting attention as an alternative and spreading the usage in wide range now a days. In addition, the infrastructure has been expanded with solar panels in response to the development of smarthome built-in with renewable energy. In this situation, visible light communication using PD has been limitedly applied in a near environment where the receiving angle of the PD and the ambient light ensure the LoS and the influence of the ambient light is small. In order to solve this problem, we have implemented visible light communication using LED lighting with large current infrastructure and solar panel with large receiving area, and proposed a circuit for restoring accurate data even in ambient light. Through this study results, it is expected that visible light communication can be more widely used and this result used as the base data for visible light communication research using the solar panel as the receiver.

• Journal of Soil and Groundwater Environment
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• v.19 no.3
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• pp.25-32
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• 2014

The amount of TPH contaminated soil treated at off-site remediation facilities is ever increasing. For the recycle of the treated-soil on farmlands, it is necessary to restore biological and physico-chemical soil characteristics and to remove residual TPH in the soil by an economic polishing treatment method such as phytoremediation. In this study, a series of experiments was performed to select suitable plant species and to devise a proper planting method for the phyto-restoration of TPH-treated soil. Rye (Secale cereale) was selected as test species through a germination test, among 5 other plants. Five 7-day-old rye seedlings were planted in a plastic pot, 20 cm in height and 15 cm in diameter. The pot was filled with TPH-treated soil (residual TPH of 1,118 mg/kg) up to 15 cm, and upper 5 cm was filled with horticulture soil to prevent TPH toxic effects and to act as root growth zone. The planted pot was cultivated in a greenhouse for 38 days along with the control that rye planted in a normal soil and the blank with no plants. After 38 days, the above-ground biomass of rye in the TPH-treated soil was 30.6% less than that in the control, however, the photosynthetic activity of the leaf remained equal on both treatments. Soil DHA (dehydrogenase activity) increased 186 times in the rye treatment compared to 10.8 times in the blank. The gross TPH removal (%) in the planted soil and the blank soil was 34.5% and 18.4%, respectively, resulting in 16.1% increase of net TPH removal. Promotion of microbial activity by root exudate, increase in soil permeability and air ventilation as well as direct uptake and degradation by planted rye may have contributed to the higher TPH removal rate. Therefore, planting rye on the TPH-treated soil with the root growth zone method showed both the potential of restoring biological soil properties and the possibility of residual TPH removal that may allow the recycle of the treated soil to farmlands.

• Korean Journal of Soil Science and Fertilizer
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• v.38 no.4
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• pp.194-201
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• 2005

Silicate (Si) fertilizers are well-known for soil amendment and to improve rice productivity as well as nitrogen efficiency. In this study, we investigated the possible reduction level of nitrogen fertilization for rice cultivation by amending Si fertilizer application. Field experiments were carried out to evaluate the productivity of rice (Oryza sativa L.) on a silt loam soil, where three levels of nitrogen (0, 110 and $165kg\;ha^{-1}$) were selected and Si fertilizer as a slag type was applied at 0, 1 and 2 times of the recommendation level (available $SiO_2\;130mg\;kg^{-1}$). Application of Si fertilizer increased significantly the rice yield and nitrogen efficiency. With increasing N uptake of rice, 1 and 2 times of recommended levels of Si fertilization could decrease nitrogen application level to about 76 and $102kg\;N\;ha^{-1}$ to produce the target yield, the maximum yield in the non-Si amended treatment. Silicate fertilizer improved soil pH and significantly increased available phosphate and Si contents. Conclusively, the Si fertilizer could be a good alternative source for soil amendment, restoring the soil nutrient balance and to reduce the nitrogen application level in rice cultivation.