• Proceedings of the Earthquake Engineering Society of Korea Conference
• /
• 2001.09a
• /
• pp.200-207
• /
• 2001

This paper introduces a methodology of seismic fragility analysis and discusses the basic input variables, focusing on the conservatism and variability of reference response spectrum. The procedures to consider the composite modal damping in the seismic fragility analysis is presented and its effects on the seismic capacity of structure is evaluated through an example analysis of the nuclear power plant structure which has typical composite modal damping characteristics. Two seismic fragility analyses were performed to obtain the seismic capacities which evaluated by considering the composite modal damping and the single damping characteristics. The results showed that the seismic fragility analysis without considering the different values of composite modal damping may considerably overestimate the seismic capacity of coupled structures.

• Proceedings of the Korea Concrete Institute Conference
• /
• 1997.10a
• /
• pp.627-632
• /
• 1997

Recently, the prestressed concrete box girder bridges are increasingly built at various locations in the world. The mechanical and structural behavior of prestressed concrete brides varies because of time-dependent material properties and sequential change of structural system due to stepwise construction. The time-dependent behavior of concrete is of importance in the design and construction of segmentally constructed and cast-in-place prestressed concrete box girder bridges. The structural response is affected b variations in creep, shrinkage properties of concrete. In this study, the example of time-dependent deformations is extended to establish how the variability in concrete properties affects the accuracy of the calculated deformations in such a bridge, and finally the results are discussed.

• Communications for Statistical Applications and Methods
• /
• v.16 no.6
• /
• pp.1031-1036
• /
• 2009

Under recent dramatic declines in response rates, various procedures have been considered among survey practitioners to reduce nonresponse in order to avoid its potential impairment to the inference. In the random digit dialing telephone surveys, substantial efforts are often required to obtain the initial contact for the screener interview. To reduce a burden with higher data collection costs, refusal conversion can be administered only to a random portion of the sample, reducing nonresponse (bias) with an expense of sample variability increment due to the associated weight adjustment. In this paper, we provide ways to determine the optimal subsampling rate using a linear cost model. Our approach for refusal subsampling is to predetermine a random portion from the full sample and to apply refusal conversion efforts if needed only to the subsample.

• Journal of the Korean Regional Science Association
• /
• v.12 no.2
• /
• pp.79-97
• /
• 1996

Local dispute resolution has evolved in response to the need for effective ways to cope with the increasing numbers and types of local disputes. Where resources are limited, where the activities of individeuals or communities affect other individuals or communities, and where interests deviate or compete, disputes are likely to emerge. Efforts to resolve local disputes vary in their particulars but generally have certain elements in common. Therefore, this study focuses upon the fundamental directions and strategies for resolving local disputes. More specifically, the purpose of this study is to examine the causes of local disputes, to suggest fundamental directions for resolving local disputes, and then to explore the strategies for resovling local disputes. In the face of rising local disputes, planners need to become more aware of the possibilities for consensual dispute than one potential path to consensus. In spite of this variability, desirable strategies in local dispute resoultion processes can be identified.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.47 no.6
• /
• pp.3-14
• /
• 2005

Accurate estimation of the spatial distribution of rainfall is critical to the successful modeling of hydrologic processes. The objective of this study is to evaluate the applicability of spatially distributed rainfall data. Spatially distributed rainfall was calculated using Kriging method and Thiessen method. The application of spatially distributed rainfall was appreciated to the runoff response from the watershed. The results showed that for each method the coefficient of determination for observed hydrograph was $0.92\~0.95$ and root mean square error was $9.78\~10.89$ CMS. Ordinary Kriging method showed more exact results than Simple Kriging, Universal Kriging and Thiessen method, based on comparison of observed and simulated hydrograph. The coefncient of determination for the observed peak flow was 0.9991 and runoff volume was 0.9982. The accuracy of rainfall-runoff prediction depends on the extent of spatial rainfall variability.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 2007.04a
• /
• pp.465-470
• /
• 2007

In order to investigate the stochastic behavior of Mindlin plate under imperfection in the material and geometrical parameters, a stochastic finite element formulation is proposed. The effects of inter-correlations between random parameters on the response variability are also observed. The contribution from the random Poisson ratio is taken into account adopting a stochastic decomposition scheme. which expands the constitutive matrix into an infinite series of sub-matrices. In order to demonstrate the adequacy of the proposed scheme, a square plate with simple and fixed support is taken as an example, and the results are compared with those given in previous research in the literature as well as with the results of Monte Carlo analysis.

• Structural Engineering and Mechanics
• /
• v.33 no.4
• /
• pp.529-537
• /
• 2009

A key parameter in the design of a laterally loaded pile is the determination of its performance level. Performance level of a pile is usually expressed as the maximum head deflection and bending moment. In general, uncertainties in the performance of a pile originates from many factors such as inherent variability of soil properties, inadequate soil exploration programs, errors taking place in the determination of soil parameters, limited calculation models as well as uncertainties in loads. This makes it difficult for practicing engineers to decide for the reliability of laterally loaded piles both in cohesive and cohesionless soils. In this paper, limit state functions and consequent performance functions are obtained for single concrete piles to predict the maximum bending moment, a widely accepted design criterion along with the permissible pile head displacement. Analyses were made utilizing three dimensional finite element method and soil-structure-interaction (SSI) effects were accounted for.

• Water Engineering Research
• /
• v.4 no.1
• /
• pp.31-43
• /
• 2003

The impacts of climate change on soil moisture in sub - Arctic watershed simulated by using the hydrologic model. A range of arbitrary changes in temperature and precipitation are applied to the runoff model to study the sensitivity of soil moisture due to potential changes in precipitation and temperature. The sensitivity analysis indicates that changes in precipitation are always amplified in soil moisture with the amplification factor for flow. The change in precipitation has effect on the soil moisture in the catchment. The percentage change in soil moisture levels can be greater than the percentage change in precipitation. Compared to precipitation, temperature increases or decreases alone have impacts on the soil moisture. These results show the potential for climate change to bring about soil moisture that may require a significant planning response. They are also indicative of the fact that hydrological impacts affecting water supply may be important in consider-ing the cost and benefits of potential climate change.

• Toxicological Research
• /
• v.7 no.2
• /
• pp.257-265
• /
• 1991

실험동물을 이용한 생식독성시험 결과를 기초로 하여 화학물질의 인체내 최기형성 발현 잠재력을 추정하는 질적인 독성평가는 비교적 용이하다. 그러나 인체에 실제로 적용할 수 있는 생식 독성 평가를 위해서는 양적인 독성평가가 요구되는데 여러가지 기본원칙의 불일치성과 검색기술등의 부조으로 아직 학문적인 평가가 어려운 실정이다. 따라서 본 seminar에서는 양적인 독성 평가의 어려운 문제점에 대한 세계적 연구추세를 소개하는 일례로서, 독일 베를린 자유대 독성학 연구소에서 다년간 수행된, 약제의 동물실험결과를 토대로 최기형 효과에 대한 평가시 고려해야 할 제반요소와 원칙에 대해 다음과 같이 소개하고자 한다.

• Biomolecules & Therapeutics
• /
• v.14 no.4
• /
• pp.183-188
• /
• 2006

The field of cytochrome P450 pharmacogenomics has progressed rapidly during the past 25 years. Recently, conjugating enzymes including sulfotransferase, acetyltransferase, glucuronosyltransferase and glutathione transferase have been also extensively studied. All the major human drug-metabolizing P450 enzymes and some conjugating enzymes have been identified and cloned, and the major gene variants that cause inter-individual variability in drug response and are related to adverse drug reactions have been identified. This information now provides the basis for the use of predictive pharmacogenomics to yield drug therapies that are more efficient and safer. Today, we understand which drugs warrant dosing based on pharmacogenomics to improve drug treatment. It is anticipated that genotyping could be used to personalize drug treatment for vast numbers of subjects, decreasing the cost of drug treatment and increasing the efficacy of drugs and health in general. It is assumed that such personalized P450 gene-based treatment which is so-called tailor(order)-made drug therapy would be relevant for 10-20% of all drug therapy in the future.