• 대한전자공학회논문지SD
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• 제38권2호
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• pp.122-127
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• 2001

간섭계를 이용하는 작업에서 가장 중요한 요구사항은 간섭 필드의 안정성을 높게 유지하는 것이며 이는 안정된 간섭패턴을 이용한 측정에 있어서 정밀성을 확보해 준다. 그러나 진동과 같은 위상잡음에 의해 안정성을 유지하기 힘들다. 본 논문에서는 BaTiO₃의 SPPCM 특성을 이용하여 마흐젠더 간섭계와 같은 전통적인 간섭계 측정시 발생 가능한 위상잡음의 영향을 줄여 안정된 간섭 패턴 확보 방법을 제안하였다. 또한 BaTiO₃로 빛을 입사시킬 때 구형렌즈를 기울여 입사빔을 원형이 아닌 타원형으로 입사시켜 원형 입사의 경우에 비해 SPPCM의 응답시간과 반사율을 개선하였다. 그리고 실험을 통해 결과를 확인하였다.

• Journal of Oral Medicine and Pain
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• 제40권3호
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• pp.89-95
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• 2015

All living organisms have a biological clock that orchestrates every biological process and function, and this internal clock operates following a circadian rhythm. This biological clock is known to influence various clinical indicators such as blood pressure and body temperature. Also, the fluctuation of signs and symptoms of diseases including pain disorders are affected by circadian rhythm. It has been reported that the pain intensity of various somatic and neuropathic pain disorders show unique pain patterns that depend on the passage of time. The generation of pain patterns could be explained by extrinsic (e.g., physical activity, tactile stimulation, ambient temperature) and also intrinsic factors (neural and neuroendocrine modulation) that are related to the circadian rhythm. It is important to recognize and identify the individual pain pattern in pain therapy to approve treatment outcome. Moreover, chronotherapeutics which considers pain patterns and pharmacokinetics in context of the circadian rhythm could produce greater analgesia in response to medication. However, only a limited number of studies handle the issue of pain patterns according to circadian rhythm and chronotherapeutics in the orofacial region. The present review intends to reflect on the most recent and relevant data concerning the bidirectional relation between pain disorders of the orofacial region and circadian patterns.

• 한국수소및신에너지학회논문집
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• 제20권5호
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• pp.378-383
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• 2009

Hydrogen is the primary fuel in fuel cell systems. Because of high inflammation and explosion possibility of hydrogen, fuel cell systems require safety measures to prevent hydrogen hazard upon leakage. In this study, a model enclosure was made by referring to a commercial residential fuel cell system and hydrogen leakage experiments and computational simulations were conducted therein. Hydrogen was injected into the cavity through leakage holes located at the bottom while its flow rate was precisely controlled using MFC. The transient sensor signals from hydrogen sensors installed inside the enclosure were recorded and analyzed. The hydrogen sensor signals showed different delay times depending on their position relative to a leakage point, which indicated that hydrogen generally moves upward and accumulates at the upper region of a closed cavity. The inflammable regions with hydrogen concentration over 4% LEL were observed to locate near the leakage hole initially, and broaden towards the upper cavity region afterward. The simulation result showed that detection time at the hydrogen sensor was similar to the pattern of experimental results. However, the maximum concentration of hydrogen had a gap between experiment and simulation at detect point due to measurement errors and reaction rate.

• 한국환경과학회지
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• 제16권12호
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• pp.1345-1353
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• 2007

The effect of salicylic acid(SA) on antioxidant system and protective mechanisms against UV-B induced oxidative stress was investigated in cucumber(Cucumis sativus L.) leaves. UV-B radiation and SA were applied separately or in combination to first leaves of cucumber seedlings, and dry matter accumulation, lipid peroxidation and activities of antioxidant enzymes were measured in both dose and time-dependant manner. UV-B exposure showed reduced levels of fresh weight and dry matter production, whereas SA treatment significantly increased them. SA noticeably recovered the UV-B induced inhibition of biomass production. UV-B stress also affected lipid peroxidation and antioxidant enzyme defense system. Malondialdehyde(MDA), a product of lipid peroxidation, was greatly increased under UV-B stress, showing a significant enhancement of a secondary metabolites, which may have antioxidative properties in cucumber leaves exposed to UV-B radiation. Combined application of UV-B and SA caused a moderate increase in lipid peroxidation. These results suggest that SA may mediate protection against oxidative stress. UV-B exposure significantly increased SOD, APX, and GR activity compared with untreated control plants. Those plants treated with 1.0 mM SA showed a similar pattern of changes in activities of antioxidant enzymes. SA-mediated induction of antioxidant enzyme activity may involve a protective accumulation of $H_2O_2$ against UV-B stress. Moreover, their activities were stimulated with a greater increase by UV-B+SA treatment. The UV-B+SA plants always presented higher values than UV-B and SA plants, considering the adverse effects of UV-B on the antioxidant cell system. ABA and JA, second messengers in signaling in response to stresses, showed similar mode of action in UV-B stress, supporting that they may be important in acquired stress tolerance. Based on these results, it can be suggested that SA may participates in the induction of protective mechanisms involved in tolerance to UV-B induced oxidative stress.

• Journal of Ecology and Environment
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• 제35권3호
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• pp.177-188
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• 2012

We analyzed crown development in Aucuba japonica Thunb. var. japonica resulting from the responses of phytoelements to habitat light conditions over a long period of time. Over the years, the degree of extension unit (EU) dimorphism and the degree of anisophylly were higher under shaded conditions than in brighter conditions. An overall temporally increasing pattern in the degree of EU dimorphism was found while no clear-cut trend was found in the case of anisophylly. EU length and number of leaves per EU co-varied in a spatio-temporal context. The number of terminal buds and their sizes acted as the key initiators of morphological differences of phytoelements which were further amplified following bud break. Leaf area density was displayed mostly in the apex peripheral layer of the crown and the apex layer received most of the incident light. There was a tradeoff between annual leaf production and mean leaf size. Depending on the heterogeneity of irradiance level within a crown, correlative growth inhibition caused higher EU mortality at brighter sites. Due to high mortality, shorter EUs had a mere role in the construction of structural framework of the crown except for the formation of some gaps. There was a strong convergence of EU dimorphism, anisophylly, EU extension growth and variations in leaf size towards formation of functional crown to reduce potential self-shading. Depending on the irradiance level, Aucuba japonica Thunb. var. japonica showed two different modes of crown expansion. At the brighter sites, individual crown expansion was progressive while at the darker sites, individual crown expanded in a diminishing manner and maintained a stable size. A plant's "growth diminishing phase" appeared earlier at shaded sites than brighter sites.

• BMB Reports
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• 제51권10호
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• pp.508-513
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• 2018

Fibronectin fragments found in the synovial fluid of patients with osteoarthritis (OA) induce the catabolic responses in cartilage. Nuclear high-mobility group protein Box 1 (HMGB1), a damage-associated molecular pattern, is responsible for the regulation of signaling pathways related to cell death and survival in response to various stimuli. In this study, we investigated whether changes induced by 29-kDa amino-terminal fibronectin fragment (29-kDa FN-f) in HMGB1 expression influences the pathogenesis of OA via an HMGB1-modulated autophagy signaling pathway. Human articular chondrocytes were enzymatically isolated from articular cartilage. The level of mRNA was measured by quantitative real-time PCR. The expression of proteins was examined by western blot analysis, immnunofluorescence assay, and enzyme-linked immunosorbent assay. Interaction of proteins was evaluated by immunoprecipitation. The HMGB1 level was significantly lower in human OA cartilage than in normal cartilage. Although 29-kDa FN-f significantly reduced the HMGB1 expression at the mRNA and protein levels 6 h after treatment, the cytoplasmic level of HMGB1 was increased in chondrocytes treated with 29-kDa FN-f, which significantly inhibited the interaction of HMGB1 with Beclin-1, increased the interaction of Bcl-2 with Beclin-1, and decreased the levels of Beclin-1 and phosphorylated Bcl-2. In addition, the level of microtubule-associated protein 1 light chain 3-II, an autophagy marker, was down-regulated in chondrocytes treated with 29-kDa FN-f, whereas the effect was antagonized by mTOR knockdown. Furthermore, prolonged treatment with 29-kDa FN-f significantly increased the release of HMGB1 into the culture medium. These results demonstrated that 29-kDa FN-f inhibits chondrocyte autophagy by modulating the HMGB1 signaling pathway.

• 산업경영시스템학회지
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• 제39권1호
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• pp.25-30
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• 2016

It is critical to forecast the maximum daily and monthly demand for power with as little error as possible for our industry and national economy. In general, long-term forecasting of power demand has been studied from both the consumer's perspective and an econometrics model in the form of a generalized linear model with predictors. Time series techniques are used for short-term forecasting with no predictors as predictors must be predicted prior to forecasting response variables and containing estimation errors during this process is inevitable. In previous researches, seasonal exponential smoothing method, SARMA (Seasonal Auto Regressive Moving Average) with consideration to weekly pattern Neuron-Fuzzy model, SVR (Support Vector Regression) model with predictors explored through machine learning, and K-means clustering technique in the various approaches have been applied to short-term power supply forecasting. In this paper, SARMA and intervention model are fitted to forecast the maximum power load daily, weekly, and monthly by using the empirical data from 2011 through 2013. $ARMA(2,\;1,\;2)(1,\;1,\;1)_7$ and $ARMA(0,\;1,\;1)(1,\;1,\;0)_{12}$ are fitted respectively to the daily and monthly power demand, but the weekly power demand is not fitted by AREA because of unit root series. In our fitted intervention model, the factors of long holidays, summer and winter are significant in the form of indicator function. The SARMA with MAPE (Mean Absolute Percentage Error) of 2.45% and intervention model with MAPE of 2.44% are more efficient than the present seasonal exponential smoothing with MAPE of about 4%. Although the dynamic repression model with the predictors of humidity, temperature, and seasonal dummies was applied to foretaste the daily power demand, it lead to a high MAPE of 3.5% even though it has estimation error of predictors.

• Radiation Oncology Journal
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• 제2권2호
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• pp.191-202
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• 1984

Biological behavior and treatment results of 33 patients with Adenoid Cystic Carcinoma (ACC) in the Head and Neck at Yonsei Cancer Confer for 10 years between 1971 and 1980 were retrospectively analysed. Most common, primary site was minor salivary glands such as maxillary sinus, nasal cavity and base of tongue. The typical biological behavior of these tumors was very slowly in growth with long time of duration(mean 19 months) from 1 month to 10 years and more frequent of nerve invasion but rare invasion of neck nodes. Local control and failure pattern in the results of treatment, 16 of 17 patients with irradiation alone were seen complete or partial response but 5 cases of locoregional recurrence, 2 cases of failure of neck node and 4 cases of distant metastasis as lung and brain. On the other hand, among 10 cases of surgery and postoperative irradiation, 2 cases of locoregional failure and 3 cases of distant metastasis as lung and bone. 2 of 4 cases with surgery alone were recurred within primary site. Actuarial overall NED survival at 3 ana 10 years were $52.6\%$ and $42.8\%$, respectively. Survival rate of 10 Patients with surgery and Postoperative irradiation was more high than 17 Patients of radiation alone. Therefore, we have known that surgery with postoperative adjunctive irradiation is most effective treatment modality of adenoid cystic carcinoma in the head and neck. Primary site, treatment modality and with or without nerve ana bone invasion have influenced on prognosis.

• 한국농촌생활과학회지
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• 제5권1호
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• pp.1-8
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• 1994

온랭 열 자극에 대하여 인체의 말초 혈류량과 심박수가 어떻게 반응하는가를 관찰하기 위하여 건강한 성인 여자 4명을 피험자로 실험군과 비교군으로 나누어 실험을 실시하였다. 실험군은 온랭열 자극의 단기 훈련을 12회 실시하고 비교군은 실험군의 초기와 말기 2회 실시하여 얻은 결과를 비교ㆍ검토하여 다음과 같은 결과를 얻었다. $\circled1$ 실험군에서의 손가락 혈류량의 초기 반응은 훈련 후에 민감해졌다. $\circled2$ 심박수는 냉수 노출시보다 온수 노출시 증가하였다. $\circled3$ 실험군과 비교군간에는 혈류량의 변화 형태와 심박수에 차이가 있었다. 이상에서 E-군과 C-군의 혈류량과 심박수에서 차이를 나타낸 것은 단기 훈련 효과에 의한 것으로 추정된다.

• 한국수자원학회논문집
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• 제33권4호
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• pp.427-435
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• 2000

침수지에 대한 신속하고 정확한 지도의 제작은 홍수재해 복구와 관리 및 예방을 위한 중요한 자료로 사용된다. 타 위성영상에 비하여 기상조건에 관계없이 영상자료의 획득이 용이한 레이더 영상을 이용하여 침수지 조사와 홍수후의 농경지 복구 상태를 파악하고자 하였다. 1999년 여름 경기도 북부 지역에 발생한 홍수 사상을 사례지로 하여 C-band RADARSAT 위성영상을 이용하였고, 침수 시점인 8월 4일 영상과 그 전후 영상을 포함하여 세 시기의 영상을 이용하였다. 영상의 기하보정 및 잡음 제거 등 전처리 과정을 거친 후 세 시기의 영상에서 나타나는 여러 지표물들의 레이더반사신호의 변화를 분석하였다. 수면, 논, 밭 산림 등의 다양한 지표물의 시기별 반사신호를 분석한 결과, 침수되었던 논에서 뚜렷한 반사신호의 차이를 관찰할 수 있었다. 또한 홍수 이후의 영상인 8월 14일 영상을 함께 분석함으로써 침수되었던 논의 복구상태에 따른 차이를 구분할 수 있었고, 이러한 결과는 세 시기의 칼라합성영상에서도 쉽게 판독되었다.