• Title/Summary/Keyword: Response Time Index

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Use of the In Vivo Single-cell Gel Electrophoresis Assay for Evaluating Genotoxicity in Clam (Single-cell Gel Electrophoresis Assay에 의한 대합에서의 In Vivo 유전독성 평가)

  • Kim Il-Yang;Hyun Chang-Kee
    • Toxicological Research
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    • v.20 no.3
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    • pp.225-232
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    • 2004
  • The suitability of the single cell gel electrophoresis (SCGE) assay as a test for the monitoring of genotoxicity of aquatic environment was evaluated. The SCGE assay was employed to detect DNA damage induced in clam (Spisula sachalinensis) exposed to a direct mutagen, N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or an indirect mutagen, benzo[a]pyrene (B[a]P). The cells of gill and digestive glands were isolated from clam by homogenization, which was the optimized cell dissociation method, and the level of DNA damage was assessed and expressed as mean tail length. In the gill cells, significant dose- and time-dependent increase was observed in the mean tail length at the concentration from 0.01 to 0.5 ppm MNNG for 96 h. The linear correlation between relative dam-age index (RDI) values was suggested to provide criteria of genotoxicity monitoring for direct acting mutagen. The dose- and time-dependent responses of the digestive glands cells were less sensitive than those of the gill cells. In contrast, the genotoxic response resulting from the exposure of 0.01~1.0 ppm B[a]P to clam revealed a higher sensitivity in the digestive glands cells than the gill cells. The comparison between the time profiles of genotoxic responses in clam and carp, the latter had been obtained in our previous study, indicated that the metabolism of genotoxic compounds in the two aquatic organisms were quite different each other. We conclude that the SCGE assay has the potential as a screening test for routine genotoxicity monitoring of aquatic organisms because of its higher sensitivity and simplicity.

Input AC Voltage Sensorless Control for a Three-Phase Z-Source PWM Rectifier (3상 Z-소스 PWM 정류기의 입력 AC 전압 센서리스 제어)

  • Han, Keun-Woo;Jung, Young-Gook;Lim, Young-Cheol
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.62 no.3
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    • pp.355-364
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    • 2013
  • Respect to the input AC voltage and output DC voltage, conventional three-phase PWM rectifier is classified as the voltage type rectifier with boost capability and the current type rectifier voltage with buck capability. Conventional PWM rectifier can not at the same time the boost and buck capability and its bridge is weak in the shoot- through state. These problems can be solved by Z-source PWM rectifier which has all characteristic of voltage and current type PWM rectifier. By shoot-through duty ratio control, the Z-source PWM rectifier can buck and boost at the same time, also, there is no need to consider the dead time. This paper proposes the input AC voltage sensorless control method of a three-phase Z-source PWM rectifier in order to accomplish the unity input power factor and output DC voltage control. The proposed method is estimated the input AC voltage by using input AC current and output DC voltage, hence, the sensor for the input AC voltage detection is no needed. comparison of the estimated and detected input AC voltage, estimated phase angle of the input voltage, the output DC voltage response for reference value, unity power factor, FFT(Fast Fourier Transform) of the estimated voltage and efficiency are verified by PSIM simulation.

Processing Sliding Windows over Disordered Streams (비순서화된 스트림 처리를 위한 슬라이딩 윈도우 기법)

  • Kim, Hyeon-Gyu;Kim, Cheol-Ki;Kim, Myoung-Ho
    • Journal of KIISE:Databases
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    • v.33 no.6
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    • pp.590-599
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    • 2006
  • Disordered streams cause two issues in processing sliding windows: i) how to place input tuples into a buffer in an increasing order efficiently and ii) how to determine a time point to process the windows from input tuples in the buffer. To address these issues, we propose a structure and method of operators for processing sliding windows. We first present a structure of the operators using an index to handle input tuples efficiently. Then, we propose a method to determine the time point to process the windows, which is called a mean-based estimation. In the proposed method, users can describe parameters required for estimation in a query specification, which provides a way for users to control the properties of query results such as the accuracy or the response time according to application requirements. Our experimental results show that the mean-based estimation provides better adaptivity and stability than the one used in the existing method.

Big Data Model for Analyzing Plant Growth Environment Informations and Biometric Informations (농작물 생육환경정보와 생체정보 분석을 위한 빅데이터 모델)

  • Lee, JongYeol;Moon, ChangBae;Kim, ByeongMan
    • Journal of Korea Society of Industrial Information Systems
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    • v.25 no.6
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    • pp.15-23
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    • 2020
  • While research activities in the agricultural field for climate change are being actively carried out, smart agriculture using information and communication technology has become a new trend in line with the Fourth Industrial Revolution. Accordingly, research is being conducted to identify and respond to signs of abnormal growth in advance by monitoring the stress of crops in various outdoor environments and soil conditions. There are also attempts to analyze data collected in real time through various sensors using artificial intelligence techniques or big data technologies. In this paper, we propose a big data model that is effective in analyzing the growth environment informations and biometric information of crops by using the existing relational database for big data analysis. The performance of the model was measured by the response time to a query according to the amount of data. As a result, it was confirmed that there is a maximum time reduction effect of 23.8%.

An Ergonomic Research on Injurious Factors Causing Musculoskeletal Disorders at a Bakery Workplace (인간공학적 접근을 통한 제빵업의 근골격계 질환 유해요인 조사)

  • 양성환;조문선;강필
    • Journal of the Korea Safety Management & Science
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    • v.6 no.2
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    • pp.35-48
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    • 2004
  • The purpose of this study is to find injurious factors and to propose an improvement plan on workers' musculoskeletal disorders at a bakery workplace through analyzing the symptom, work posture and quantitative estimate. For this study, a survey and ergonomic estimate methods were adopted. According to the survey, it was analyzed that 429 workers corresponding to 68.2% of the response have been experienced the symptoms of musculoskeletal disorders such as an ache, prickle and numbness. The result of QEC analysis shows that shoulder and waist are highly exposed to musculoskeletal disease. The result of RULA analysis shows that injurious factors of muscle, weight and repeated operations are a little higher than those of operation posture. The result of SI estimate shows that pre-treatment of making bread requiring highly repeated operation gets the highest point of 81, on the other hand, chocolate-coating job requiring relatively low speed and short time gets the point of 4.5. Based on the analyzed results, improvement plan to prevent the musculoskeletal disorders against injurious working process of a bakery workplace. The goal of this study is to propose the improved scheme that prevents the workers against musculoskeletal disorders. A questionnaire and an ergonomic assessment method were adopted to analyze the symptoms of workers' musculoskeletal disorders, and an analysis of working postures and a quantitative assessment on various processes were performed to find out harmful factors of workplace.

Identification of Fractional-derivative-model Parameters of Viscoelastic Materials Using an Optimization Technique (최적화 기법을 이용한 점탄성물질의 분수차 미분모델 물성계수 추정)

  • Kim, Sun-Yong;Lee, Doo-Ho
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.12 s.117
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    • pp.1192-1200
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    • 2006
  • Viscoelastic damping materials are widely used to reduce noise and vibration because of its low cost and easy implementation, for examples, on the body structure of passenger cars, air planes, electric appliances and ships. To design the damped structures, the material property such as elastic modulus and loss factor is essential information. The four-parameter fractional derivative model well describes the dynamic characteristics of the viscoelastic damping materials with respect to both frequency and temperature. However, the identification procedure of the four-parameter is very time-consuming one. In this study a new identification procedure of the four-parameters is proposed by using an FE model and a gradient-based numerical search algorithm. The identification procedure goes two sequential steps to make measured frequency response functions(FRF) coincident with simulated FRFs: the first one is a peak alignment step and the second one is an amplitude adjustment step. A numerical example shows that the proposed method is useful in identifying the viscoelastic material parameters of fractional derivative model.

Analysis on running safety of train on bridge with wind barriers subjected to cross wind

  • Zhang, T.;Xia, H.;Guo, W.W.
    • Wind and Structures
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    • v.17 no.2
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    • pp.203-225
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    • 2013
  • An analysis framework for vehicle-bridge dynamic interaction system under turbulent wind is proposed based on the relevant theory of wind engineering and dynamics. Considering the fluctuating properties of wind field, the stochastic wind velocity time history is simulated by the Auto-Regressive method in terms of power spectral density function of wind field. The bridge is represented by three-dimensional finite element model and the vehicle by a multi-rigid-body system connected by springs and dashpots. The detailed calculation formulas of unsteady aerodynamic forces on bridge and vehicle are derived. In addition, the form selection of wind barriers, which are applied as the windbreak measures of newly-built railways in northwest China, is studied based on the suggested evaluation index, and the suitable values about height and porosity rate of wind barriers are studied. By taking a multi-span simply-supported box-girder bridge as a case study, the dynamic response of the bridge and the running safety indices of the train traveling on the bridge with and without wind barriers are calculated. The limit values of train speed with respect to different wind velocities are proposed according to the allowance values in the design code.

Dynamic characteristics of curved inhomogeneous nonlocal porous beams in thermal environment

  • Ebrahimi, Farzad;Daman, Mohsen
    • Structural Engineering and Mechanics
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    • v.64 no.1
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    • pp.121-133
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    • 2017
  • This paper proposes an analytical solution method for free vibration of curved functionally graded (FG) nonlocal beam supposed to different thermal loadings, by considering porosity distribution via nonlocal elasticity theory for the first time. Material properties of curved FG beam are assumed to be temperature-dependent. Thermo-mechanical properties of porous FG curved beam are supposed to vary through the thickness direction of beam and are assumed to be temperature-dependent. Since variation of pores along the thickness direction influences the mechanical and physical properties, porosity play a key role in the mechanical response of curved FG structures. The rule of power-law is modified to consider influence of porosity according to even distribution. The governing equations of curved FG porous nanobeam under temperature field are derived via the energy method based on Timoshenko beam theory. An analytical Navier solution procedure is used to achieve the natural frequencies of porous FG curved nanobeam supposed to thermal loadings with simply supported boundary condition. The results for simpler states are confirmed with known data in the literature. The effects of various parameters such as nonlocality, porosity volume fractions, type of temperature rising, gradient index, opening angle and aspect ratio of curved FG porous nanobeam on the natural frequency are successfully discussed. It is concluded that these parameters play key roles on the dynamic behavior of porous FG curved nanobeam. Presented numerical results can serve as benchmarks for future analyses of curve FG nanobeam with porosity phases.

Comparative Analysis for Real-Estate Price Index Prediction Models using Machine Learning Algorithms: LIME's Interpretability Evaluation (기계학습 알고리즘을 활용한 지역 별 아파트 실거래가격지수 예측모델 비교: LIME 해석력 검증)

  • Jo, Bo-Geun;Park, Kyung-Bae;Ha, Sung-Ho
    • The Journal of Information Systems
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    • v.29 no.3
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    • pp.119-144
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    • 2020
  • Purpose Real estate usually takes charge of the highest proportion of physical properties which individual, organizations, and government hold and instability of real estate market affects the economic condition seriously for each economic subject. Consequently, practices for predicting the real estate market have attention for various reasons, such as financial investment, administrative convenience, and wealth management. Additionally, development of machine learning algorithms and computing hardware enhances the expectation for more precise and useful prediction models in real estate market. Design/methodology/approach In response to the demand, this paper aims to provide a framework for forecasting the real estate market with machine learning algorithms. The framework consists of demonstrating the prediction efficiency of each machine learning algorithm, interpreting the interior feature effects of prediction model with a state-of-art algorithm, LIME(Local Interpretable Model-agnostic Explanation), and comparing the results in different cities. Findings This research could not only enhance the academic base for information system and real estate fields, but also resolve information asymmetry on real estate market among economic subjects. This research revealed that macroeconomic indicators, real estate-related indicators, and Google Trends search indexes can predict real-estate prices quite well.

Evauation of the Nutritive Quality of Proteins by Using Slope-Ratio Assay (경사비율 방법에 의한 단백질의 영양가 평가)

  • 오훈일
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.3
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    • pp.197-202
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    • 1991
  • Young rats were fed diets containing three different proteins : lactalbumin, soy and peanut protein, each fed at levels from zero to over 35% of the diet over a 2-week time period. Response was measured at the amount of body weight gain in relation to total nitrogen consumption as a measure of dose. The slopes of the regression of the proteins in the linear range were compared to that of the standard lactalbumin. The relative growth index of soy and peanut protein was calculated to be 78.4 and 55.7, respectively. Thus, it is concluded that the slop-ratio assay is a very useful method for the evaluation of the nutritional quality of proteins under well-designed experimental conditions.

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